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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | A Cost Analysis of Supply Chain Flexibility Configurations 显示文摘 | APRILE D CLAUDIO A C GIANNOCCARO L | 2006 | International Journal of Services Teehnol-ogy and Management2006，7，5： | 1 |
| 3 | Obtaining CeO2-ZrO2 mixed oxides by coprecipitation:role of preparation conditions显示文摘 | Sonia L Claudio A T Roberto R A | 2005 | Applied Catalysis B:Environmental2005，58，34： | 1 |
| 4 | Modeling the contribution of specific grinding pressure for the calculation of HPGR product size distribution 显示文摘 | Claudio L S Vladmir K A Leonard G A | 2009 | Minerals Engineering2009，22，78： | 1 |
| 5 | Phthalate exposure associated with self-reported diabetes among Mexican women显示文摘 | Katherine Svensson Raúl U. Hernández-Ramírez Ana Burguete-García Mariano E. Cebrián Antonia M. Calafat Larry L. Needham Luz Claudio Lizbeth López-Carrillo | 2011 | Environmental Research2011，，6： | 1 |
| 6 | Differential host gene expression in ceils infected with highly pathogenic H5N1 avian influenza viruses显示文摘 | Luciana S Claudio L A Carlos E | 2008 | Veterinary Immunology and Immunopathology2008，125，： | 1 |
| 7 | Newcastle dis ease:Evolution of genotypes and the related diagnostic challenges显示文摘 | Patti J M Eduardo L D Claudio L A | 2010 | Infect Genet Evol2010，10，： | 1 |
| 8 | Cationic rhodium (Ⅰ) complexes containing 4, 4'-disubstituted 2,2'-bipyridines: A systematic variation on electron density over the metal centre 显示文摘 | Paulo E A R Claudio L D | 2006 | J Organomet Chem2006，691，： | 1 |
| 9 | Botanical origin and chemical composition of Brazilian propolis 显示文摘 | Yong K P Severino M A Claudio L A | 2002 | Food Chemistry2002，，50： | 1 |
| 10 | Mechanisms ofAutoimmune Neuropathies显示文摘 | Brosnan C F Claudio L Tansey F A | 1990 | Ann Neurol1990，27，： | 1 |
| 11 | Point of collapse methods applied to AC/DC power systems显示文摘 | Claudio A C Fernando LA Christopher L D | 1992 | IEEE Trans on Power System1992，7，2： | 1 |
| 12 | Modeling and predictive control of a new injection system for compressed natural gas engines显示文摘 | Paolo L Bruno M Claudio A | 2008 | Control Engineering Practice2008，16，10： | 1 |
| 13 | Performance of modified montmorillonite clay in mercury adsorption process and thermodynamic studies显示文摘 | Denis L G Claudio A Rubia R V | 2008 | Inorganic Chemistry Communications2008，11，1： | 1 |
| 14 | Adsorption of mercury cation on chemically modified clay显示文摘 | Denis L G Rubia R V Claudio A | 2009 | Materials Research Bulletin2009，44，3： | 1 |
| 15 | Genetic susceptibility to lead poisoning 显示文摘 | Onalaja A O Claudio L | 2000 | Environ Health Perspect2000，108，1： | 1 |
| 16 | Towards the efficiency limits of silicon solar cells: How thin is too thin? 显示文摘 | Piotr K Claudio A L | 2015 | Solar Energy Mater Solar Cells2015，143，： | 1 |
| 17 | Glycerol acetals as anti- freezing additives for biodiesel显示文摘 | Paulo H R Valter L C Claudio J A | 2010 | Bioresource technology2010，101，15： | 1 |
| 18 | Obtaining CeO2-ZrO2 mixed oxides by coprecipitation:role of preparation conditions显示文摘 | Sonia L Claudio A T Roberto R A | 2005 | Applied Catalysis B:Environmental2005，58，20： | 1 |
| 19 | Characterization of P30,a highly antigenic membrane and secreted protein of African swine fe-ver virus显示文摘 | Claudio L Carlos A Aleiandro B | 2010 | Virology2010，189，： | 1 |
| 20 | (;haracterization of P30,a highly antigenic membrane and secreted pro- tein of African swine fever virus显示文摘 | Claudio L Carlos A Aleiandro B | 1992 | Virology1992，189，： | 1 |
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