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| 1 | Adherence to immunosuppressor medication in renal transplanted patients显示文摘Non-adherence is a priority public health concern. Non-adherence means not taking medications, missing medications, taking too much, not taking enough, wrongtiming, wrong dose and/or wrong pill, but may also refer to missing appointments, not booking appointments, not doing blood work, not returning calls and/or refusal to follow the treatment regimen. In renal transplantation, adherence to immunosuppressive medication is a fundamental requisite in order to preserve graft function, since non-adherence is one of the main causes for late acute rejection, incomplete recovery after rejection treatment, chronic graft dysfunction, graft loss, and death. Transplantation failure due to treatment nonadherence is economically, socially, ethically and morally unjustifiable. This is a very prevalent issue: in some studies, its incidence is as high as 70% of patients. The self-reported nonadherence levels found in certain studies, including those performed immediately after transplantation show the need for early and continued intervention after kidney transplantation in order to maximise adherence and consequently clinical outcomes. There is not a single method to assess non adherence, thus combining several measures increases diagnostic accuracy. Electronic monitoring with a microdevice that records each time a pill bottle is opened is considered the 'gold standard' for measuring adherence, but selfreport at a confidential interview was the best measure of adherence. Thus non-adherence risk can be effectively assessed using clinically available assessment tools. Medication Adherence Scale, Brief Medical Questionnaire, Immunosuppressant Therapy Adherence Scale, Immunosuppressant Therapy Barrier Scale, Long-Term Medication Behavior Self-Efficacy Scale and Simplified Medication Adherence Questionnaire are some of the self-reported questionnaires. There are multiple factors associated with non-adherence in immunosuppressant therapy: Younger patients(adolescent, especially), poor health coverage, poor social support, unmarried, no family, non-Caucasian, immigrant, lower income, lower socioeconomic class, greater parental distress and lower family cohesion; complex medical regimens, higher number of drugs, longer time after transplant, toxicity, side effects, poor tolerance to medication, higher number of physicians involved, poor provider-patient rapport; psychological(dependency, high levels of anxiety and hostility, poorer behavioral functioning and greater distress in children) and psychiatric(depression) illnesses, low self-efficacy with medicine intake, perception of immunosuppressive therapy as not been necessary to preserve kidney function, forgetfulness, rebelliousness, poor perception of health, poor satisfaction, low Health-related quality of life, addictions, lack of coping strategies and avoidance behavior; patient morbidity: comorbidity, receiving a transplant from a live donor, retransplantation, and noninsulin-dependent diabetes. The most frequent strategies to promote medication-taking must focus on modifiable risk factors. Reasons for non-adherence are complex and diverse and any successful intervention aimed at improving adherence must be multidimensional. Although effective intervention strategies are needed to improve immunosuppressant therapy adherence, few intervention studies have been conducted in the adult renal transplant population. In this study, we perform an exhaustive review of the different strategies reported in the literature. A number of key reasons for non-adherence are also provided. | Francisco Ortega Carmen Díaz-Corte Covadonga Valdés | 2015 | World Journal of Clinical Urology2015，4，1： | 5 |
| 2 | Non-alcoholic Steatohepatitis (NASH) and Hepatocellular Carcinoma显示文摘 | Antonio Cuadrado Aitor Orive Covadonga García-Suárez Agustín Domínguez Jose Carlos Fernández-Escalante Javier Crespo Fernando Pons-Romero | 2005 | Obesity Surgery2005，，3： | 4 |
| 3 | A DNA methylation signature associated with aberrant promoter DNA hypermethylation of DNMT3B in human colorectal cancer显示文摘 | Covadonga Huidobro Rocío G. Urdinguio Ramón María Rodríguez Cristina Mangas Vincenzo Calvanese Pablo Martínez-Camblor Cecilia Ferrero Adolfo Parra-Blanco Luis Rodrigo álvaro J. Obaya Laura Suárez-Fernández Aurora Astudillo Henar Hernando Esteban Ballestar | 2011 | European Journal of Cancer2011，，14： | 1 |
| 4 | Antibody-mediated neutralization of African swine fever virus: Myths and facts显示文摘 | José M. Escribano Inmaculada Galindo Covadonga Alonso | 2012 | Virus Research2012，，： | 1 |
| 5 | Visualization of the African swine fever virus infection in living cells by incorporation into the virus particle of green fluorescent protein-p54 membrane protein chimera显示文摘 | Bruno Hernaez Jose M. Escribano Covadonga Alonso | 2006 | Virology2006，，1： | 1 |
| 6 | The African swine fever virus dynein-binding protein p54 induces infected cell apoptosis显示文摘 | Bruno Hernáez Gema D??az-Gil Mónica Garc??a-Gallo José Ignacio Quetglas Ignacio Rodr??guez-Crespo Linda Dixon José M Escribano Covadonga Alonso | 2004 | FEBS Letters2004，，1： | 1 |
| 7 | 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase and Isoprenylation Inhibitors Induce Apoptosis of Vascular Smooth Muscle Cells in Culture显示文摘 | Carlos Guijarro Luis Miguel Blanco-Colio Monica Ortego Covadonga Alonso Alberto Ortiz Juan Jose Plaza Cristina Diaz Gonzalo Hernandez Jesus Egido | 1998 | Circulation Research1998，，5： | 1 |
| 8 | Yeast Species Associated with Orange Juice: Evaluation of Different Identification Methods 显示文摘 | Covadonga R A Jacqueline K B Lorrie M F | 2002 | Applied Environmental Microbiolgy2002，68，： | 1 |
| 9 | 综述非洲猪瘟病毒显示文摘非洲猪瘟(African swine fever,ASF)是一种具有高度传染性的猪病毒病。在家猪中可导致接近100%的高死亡率。ASF是由ASF病毒(ASF Virus,ASFV)引起,ASFV是一种较大的双链DNA病毒,主要在巨噬细胞的细胞质中复制,ASFV是Asfarviridae科Asfivirus属唯一的成员。ASFV的天然宿主包括野猪和Ornithodoros属的节肢动物媒介。ASFV在其储存宿主的感染通常是无症状的,并且发展为持续感染。相反,ASFV对家猪的感染可导致致命的出血热,目前且无有效疫苗。确定ASFV毒力相关基因,以及探索病毒逃避宿主免疫应答的机制,公认为是影响疫苗开发的关键步骤。此外,病毒产物与宿主的相互作用与病毒复制紧密相关,为寻找防治该疾病的潜在靶标提供有效信息。 | 刘颖昳(编译) Inmaculada Galindo Covadonga Alonso | 2019 | 猪业科学2019，36，9： | 1 |
| 10 | Direct Measurement of Proximal Isovelocity Surface Area by Single-Beat Three-Dimensional Color Doppler Echocardiography in Mitral Regurgitation: A Validation Study显示文摘 | Jose Alberto de Agustín Pedro Marcos-Alberca Covadonga Fernandez-Golfin Alexandra Gon?alves Gisela Feltes Ivan Javier Nu?ez-Gil Carlos Almeria Jose Luis Rodrigo Leopoldo Perez de Isla Carlos Macaya Jose Zamorano | 2012 | Journal of the American Society of Echocardiography2012，，8： | 1 |
| 11 | Yeast Species Associated with Orange Juice: Evaluation of Different Identication Methods 显示文摘 | Covadonga R A Burns J K Friedrich L M | 2002 | Applied and Environmental Microbiology2002，68，4： | 1 |
| 12 | Non-alcoholic Steatohepatitis (NASH) and Hepatocellular Carcinoma显示文摘 | Antonio Cuadrado Aitor Orive Covadonga García-Suárez Agustín Domínguez Jose Carlos Fernández-Escalante Javier Crespo Fernando Pons-Romero | 2005 | Obesity Surgery2005，，3： | 1 |
| 13 | Population-Based Study of Out-of-Hospital Sudden Cardiovascular Death: Incidence and Causes of Death in Middle-Aged Adults显示文摘 | Benito Morentin Covadonga Audicana | 2010 | 2010，，1： | 1 |
| 14 | Yeast species associated with orange juice:Evaluation of different identification methods显示文摘 | Covadonga R Arias Jacqueline K | 2002 | Appl Environ Microbiol2002，，4： | 1 |
| 15 | Yeast species associated with orange juice: evaluation of different identification methods显示文摘 | Covadonga R Jacqueline K Burns S | 2002 | Appl Environ Microb2002，，4： | 1 |
| 16 | Financial risk prediction using rough sets tools: a case study 显示文摘 | Santiago Eibe Raquel Del Saz Covadonga Fernandez Oscar Marbfn Ernestina Menasalvas Concepci6n P6rez | 2005 | Rough Sets Fuzzy Sets Data Mining And Granular Computing2005，，42： | 1 |
| 17 | Identification and characterization of an intervening sequence within the 23S ribosomal RNA gence of Edwardsiella ictaluri 显示文摘 | Yin Feng Z Covadonga R A | 2007 | Systematic and Applied Microbiology2007，30，： | 1 |
| 18 | Policy Learning, Policy Diffusion, and the Making of a New Order 显示文摘 | Meseguer Covadonga | 2005 | Annals of the American Academy of Political and Social Science2005，598，1： | 1 |
| 19 | Theoretical and experimental study on the fluidity performance of hard-to-fluidize carbon nanotubes-based CO_(2) capture sorbents显示文摘Carbon nanotubes-based materials have been identified as promising sorbents for efficient CO_(2)capture in fluidized beds,suffering from insufficient contact with CO_(2)for the high-level CO_(2)capture capacity.This study focuses on promoting the fluidizability of hard-to-fluidize pure and synthesized silica-coated amine-functionalized carbon nanotubes.The novel synthesized sorbent presents a superior sorption capacity of about 25 times higher than pure carbon nanotubes during 5 consecutive adsorption/regeneration cycles.The low-cost fluidizable-SiO_(2)nanoparticles are used as assistant material to improve the fluidity of carbon nanotubes-based sorbents.Results reveal that a minimum amount of 7.5 and 5 wt%SiO_(2)nanoparticles are required to achieve an agglomerate particulate fluidization behavior for pure and synthesized carbon nanotubes,respectively.Pure carbon nanotubes+7.5 wt%SiO_(2)and synthesized carbon nanotubes+5 wt%SiO_(2)indicates an agglomerate particulate fluidization characteristic,including the high-level bed expansion ratio,low minimum fluidization velocity(1.5 and 1.6 cm·s^(–1)),high Richardson−Zaki n index(5.2 and 5.3>5),and lowΠvalue(83.2 and 84.8<100,respectively).Chemical modification of carbon nanotubes causes not only enhanced CO_(2)uptake capacity but also decreases the required amount of silica additive to reach a homogeneous fluidization behavior for synthesized carbon nanotubes sorbent. | Mahsa Javidi Nobarzad Maryam Tahmasebpoor Mohammad Heidari Covadonga Pevida | 2022 | Frontiers of Chemical Science and Engineering2022，16，10： | 0 |
| 20 | Enhanced capacity to CO2 sorption in humid conditions with a K-doped biocarbon显示文摘Solid sorbents with enhanced capacity and selectivity towards CO2 are crucial in the design of an efficient capture process.Among the possible alternatives,K2CO3-doped activated carbons have shown high CO2 capture capacity and rapid carbonation reaction rate.In this work,a sustainable and low-cost approach is developed with a biomass-based activated carbon or biocarbon as support.The CO2 capture performance in cyclic sorption–desorption operation and the sorption kinetics have been investigated under different scenarios in a purpose-built fixed-bed set-up.Independent of the H2O concentration in the flue gas,a constant relative humidity(~20%)in the K2CO3-doped biocarbon bed promoted the carbonation reaction and boosted the CO2 sorption capacity(1.92 mmol/g at 50℃ and 14 kPa partial pressure of CO2).Carbonation is slower than physical adsorption of CO2 but wise process design could tune the operation conditions and balance capture capacity and sorption kinetics. | Nausika Querejeta FernANDo Rubiera Covadonga Pevida | 2019 | Journal of Energy Chemistry2019，28，7： | 0 |
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