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| 1 | The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate显示文摘 | Patrick S. Ward Jay Patel David R. Wise Omar Abdel-Wahab Bryson D. Bennett Hilary A. Coller Justin R. Cross Valeria R. Fantin Cyrus V. Hedvat Alexander E. Perl Joshua D. Rabinowitz Martin Carroll Shinsan M. Su Kim A. Sharp Ross L. Levine Craig B. Thompson | 2010 | Cancer Cell2010，，3： | 2 |
| 2 | Clinical determinants of aspirin resistance in diabetes显示文摘 | Hussein N. Yassine Grace Davis-Gorman Craig S. Stump Stephen S. Thomson Justin Peterson Paul F. McDonagh | 2010 | Diabetes Research and Clinical Practice2010，，1： | 1 |
| 3 | Diagnosis, assessment, and treatment of bone turnover abnormalities in renal osteodystrophy显示文摘 | Kevin J Martin Klaus Olgaard Jack W Coburn Giorgio M Coen Masafumi Fukagawa Craig Langman Hartmut H Malluche James T McCarthy Shaul G Massry Otto Mehls Isidro B Salusky Justin M Silver Miroslaw T Smogorzewski Eduardo M Slatopolsky Linda McCann | 2004 | American Journal of Kidney Diseases2004，，3： | 1 |
| 4 | Dendronized linear polymers via'click chemistry'显示文摘 | Brett Helms Justin L Mynar Craig J Hawk | 2004 | Journal of the American Chemical Society2004，126，15： | 1 |
| 5 | The natural environment, innova- tion, and finn performance: A comparative study显示文摘 | Craig Justin Dibrell Clay | 2006 | Family Business Review2006，19，4： | 1 |
| 6 | Empowering leadership: An examination of mediating mechanisms within a hierarchical structure显示文摘 | Robert P. Vecchio Joseph E. Justin Craig L. Pearce | 2010 | The Leadership Quarterly2010，，3： | 1 |
| 7 | Voxel size and measures of individual resorption cavities in three-dimensional images of cancellous bone显示文摘 | Evgeniy V. Tkachenko Craig R. Slyfield Ryan E. Tomlinson Justin R. Daggett David L. Wilson Christopher John Hernandez | 2009 | Bone2009，，3： | 1 |
| 8 | Improving diabetic and hypertensive retinopathy with a medical food containing L-methylfolate: a preliminary report显示文摘Background:Homocysteine and vitamin D may play a role in the development of diabetic and hypertensive retinopathy in patients with diabetes mellitus(DM)and hypertension.Supplementing food with L-methylfolate and vitamin D theoretically may improve diabetic and hypertensive retinopathy,however,the outcome of these nutritional approaches has not been fully examined.A retrospective case review was done of cases of retinopathy reversal in patients on Ocufolin^(TM) and a similar nonprescription multivitamin,Eyefolate^(TM).In this study,they were administered L-methylfolate(2.7 mg and 3.0 mg,respectively)and vitamin D3(4500 IU each).These dosages are significantly above the RDA but well below levels associated with toxicity.Case presentation:Seven patients had nonproliferative diabetic retinopathy(NPDR)and some of them had hypertension.One patient had only hypertensive retinopathy.All patients were instructed to take Ocufolin^(TM)medical food as a food supplement.Baseline genetic testing for MTHFR polymorphisms was conducted.Fundus photography was used to document the fundus condition of the enrolled eyes in 8 NPDR patients at the initial and follow-up visits.Microaneurysms(MA)and exudates were observed to be improved in some trial patients.All subjects had one or more MTHFR polymorphisms.All had diabetic retinopathy,hypertensive retinopathy,or both.MAs were resolved,and exudates were decreased in 8/8 cases after taking the medical food.Retinal edema was found in 2/8 cases and improved or resolved in both cases after taking the medical food or the supplement.The best corrected visual activity was stable or improved in 8/8 cases.Conclusion:We report a series of diabetic and hypertensive retinopathy cases with MTHFR polymorphisms and the improvement of retinal microvasculature(mainly MAs)in serial fundus photography after taking a medical food or supplement containing L-methylfolate and vitamin D.It appears that the use of nutritional supplements and medical foods containing L-methylfolate and vitamin D may be effective in facilitating the improvement of diabetic and hypertensive retinopathy. | Jianhua Wang Craig Brown Ce Shi Justin Townsend Giovana Rosa Gameiro Peng Wang Hong Jiang | 2019 | Eye and Vision2019，6，1： | 1 |
| 9 | Balanced Scorecards to Drive the Strategic Planning of Family Firms显示文摘 | JUSTIN CRAIG KEN MOORES | 2005 | FAMILY BUSINESS REVIEW2005，，2： | 1 |
| 10 | Water and salinity stress in grapevines: early and late changes in transcript and metabolite profiles显示文摘 | Grant R. Cramer Ali Ergül Jerome Grimplet Richard L. Tillett Elizabeth A. R. Tattersall Marlene C. Bohlman Delphine Vincent Justin Sonderegger Jason Evans Craig Osborne David Quilici Karen A. Schlauch David A. Schooley John C. Cushman | | 0，2007，： | 1 |
| 11 | Novel double contrast MRI technique for intramyocardial detection of percutaneously transplanted autologous cells显示文摘 | Dmitri V.Baklanov Ebo D.Demuinck Craig A.Thompson Justin D.Pearlman | 2004 | Magn Reson Med2004，，6： | 1 |
| 12 | Imaging findings of femoroacetabular impingement syndrome显示文摘 | Douglas P. Beall Clifford F. Sweet Hal D. Martin Craig L. Lastine David E. Grayson Justin Q. Ly Jon R. Fish | 2005 | Skeletal Radiology2005，，11： | 1 |
| 13 | A Novel Model of Urinary Tract Differentiation, Tissue Regeneration, and Disease: Reprogramming Human Prostate and Bladder Cells into Induced Pluripotent Stem Cells显示文摘 | Mohammad Moad Deepali Pal Anastasia C. Hepburn Stuart C. Williamson Laura Wilson Majlinda Lako Lyle Armstrong Simon W. Hayward Omar E. Franco Justin M. Cates Sarah E. Fordham Stefan Przyborski Jane Carr-Wilkinson Craig N. Robson Rakesh Heer | 2013 | European Urology2013，，： | 1 |
| 14 | Politywide Analysis and Imperial Political Economy:The Relationship between Valley Political Complexity and Administrative Centers in the Wari Empire of the Central Andes显示文摘 | Jennings Justin Craig Nathan | 2001 | Joumal of Anthropological Archaeology2001，20，4： | 1 |
| 15 | The Effect of Grape Seed Extract on Cardiovascular Risk Markers: A Meta-Analysis of Randomized Controlled Trials显示文摘 | Harm H.H. Feringa Dayne A. Laskey Justine E. Dickson Craig I. Coleman | 2011 | Journal of the American Dietetic Association2011，，8： | 1 |
| 16 | Nalbuphine-induced psychosis treated with naloxone显示文摘 | LAURA A. SIEMIANOWSKI JUSTIN P. ROSENHECK CRAIG B. WHITMAN | 2014 | American Journal of Health-System Pharmacy2014，，9： | 1 |
| 17 | Nutritional and medical food therapies for diabetic retinopathy显示文摘Diabetic retinopathy(DR)is a form of microangiopathy.Reducing oxidative stress in the mitochondria and cell membranes decreases ischemic injury and end-organ damage to the retina.New approaches are needed,which reduce the risk and improve the outcomes of DR while complementing current therapeutic approaches.Homocysteine(Hcy)elevation and oxidative stress are potential therapeutic targets in DR.Common genetic polymorphisms such as those of methylenetetrahydrofolate reductase(MTHFR),increase Hcy and DR risk and severity.Patients with DR have high incidences of deficiencies of crucial vitamins,minerals,and related compounds,which also lead to elevation of Hcy and oxidative stress.Addressing the effects of the MTHFR polymorphism and addressing comorbid deficiencies and insufficiencies reduce the impact and severity of the disease.This approach provides safe and simple strategies that support conventional care and improve outcomes.Suboptimal vitamin co-factor availability also impairs the release of neurotrophic and neuroprotective growth factors.Collectively,this accounts for variability in presentation and response of DR to conventional therapy.Fortunately,there are straightforward recommendations for addressing these issues and supporting traditional treatment plans.We have reviewed the literature for nutritional interventions that support conventional therapies to reduce disease risk and severity.Optimal combinations of vitamins B1,B2,B6,L-methylfolate,methylcobalamin(B12),C,D,natural vitamin E complex,lutein,zeaxanthin,alpha-lipoic acid,and n-acetylcysteine are identified for protecting the retina and choroid.Certain medical foods have been successfully used as therapy for retinopathy.Recommendations based on this review and our clinical experience are developed for clinicians to use to support conventional therapy for DR.DR from both type 1 diabetes mellitus(T1DM)and type 2 diabetes mellitus(T2DM)have similar retinal findings and responses to nutritional therapies. | Ce Shi Peng Wang Shriya Airen Craig Brown Zhiping Liu Justin H.Townsend Jianhua Wang Hong Jiang | 2020 | Eye and Vision2020，7，1： | 1 |
| 18 | A 24 hour naproxen dose on gastrointestinal distress and performance during cycling in the heat显示文摘Using a double-blind,randomized and counterbalanced,cross-over design,we assessed naproxen's effects on gastrointestinal(GI)distress and performance in eleven volunteers(6 male,5 female).Participants completed 4 trials:1)placebo and ambient);2)placebo and heat;3)naproxen and ambient;and 4)naproxen and heat.Independent variables were one placebo or 220 mg naproxen pill every 8 h(h)for 24 h and ambient(22.7±1.8℃)or thermal environment(35.7±1.3℃).Participants cycled 80 min at a steady heart rate then 10 min for maximum distance.Perceived exertion was measured throughout cycling.Gastrointestinal distress was assessed pre-,during,post-,3 h post-,and 24 h post-cycling using a GI index for upper,lower,and systemic symptoms.No statistically significant differences occurred between conditions at any time for GI symptoms or perceived exertion,distance,or heart rate during maximum effort.A 24 h naproxen dose did not significantly affect performance or cause more frequent or serious GI distress when participants were euhydrated and cycling at moderate intensity in a thermal environment. | Dawn M.Emerson J.Mark Davis Stephen CL.Chen Toni M.Torres-McGehee Craig E.Pfeifer Charles C.Emerson Joseph D.Bivona Justin V.Stone | 2020 | Sports Medicine and Health Science2020，2，1： | 0 |
| 19 | Concomitant atopic dermatitis and narcolepsy type 1:psychiatric implications and challenges in management显示文摘Atopic dermatitis(AD)and narcolepsy type 1(NT1)are two distinct diseases that have not been classically shown to be related.The potential connection between the known immunological aetiology of AD and the proposed autoimmune pathophysiology of dysregulation in NT1;however,is the subject of ongoing speculation and debate with advances in gene sequencing and technology.Here,we present a case of a patient with concomitant refractory AD and NT1 and review the current research on their immunological relationship and the challenges in management relative to disease burden and psychiatric comorbidities. | Justin Chin Craig Bearison Nanette Silverberg Mary Lee Wong | 2019 | General Psychiatry2019，32，5： | 0 |
| 20 | Nutritional and medical food therapies for diabetic retinopathy显示文摘Diabetic retinopathy(DR)is a form of microangiopathy.Reducing oxidative stress in the mitochondria and cell membranes decreases ischemic injury and end-organ damage to the retina.New approaches are needed,which reduce the risk and improve the outcomes of DR while complementing current therapeutic approaches.Homocysteine(Hcy)elevation and oxidative stress are potential therapeutic targets in DR.Common genetic polymorphisms such as those of methylenetetrahydrofolate reductase(MTHFR),increase Hcy and DR risk and severity.Patients with DR have high incidences of deficiencies of crucial vitamins,minerals,and related compounds,which also lead to elevation of Hcy and oxidative stress.Addressing the effects of the MTHFR polymorphism and addressing comorbid deficiencies and insufficiencies reduce the impact and severity of the disease.This approach provides safe and simple strategies that support conventional care and improve outcomes.Suboptimal vitamin cofactor availability also impairs the release of neurotrophic and neuroprotective growth factors.Collectively,this accounts for variability in presentation and response of DR to conventional therapy.Fortunately,there are straightforward recommendations for addressing these issues and supporting traditional treatment plans.We have reviewed the literature for nutritional interventions that support conventional therapies to reduce disease risk and severity.Optimal combinations of vitamins B1,B2,B6,L-methylfolate,methylcobalamin(B12),C,D,natural vitamin E complex,lutein,zeaxanthin,alpha-lipoic acid,and n-acetylcysteine are identified for protecting the retina and choroid.Certain medical foods have been successfully used as therapy for retinopathy.Recommendations based on this review and our clinical experience are developed for clinicians to use to support conventional therapy for DR.DR from both type 1 diabetes mellitus(T1DM)and type 2 diabetes mellitus(T2DM)have similar retinal findings and responses to nutritional therapies. | Ce Shi Peng Wang Shriya Airen Craig Brown Zhiping Liu Justin HTownsend Jianhua Wang Hong Jiang | 2022 | Eye and Vision2022，8，6： | 0 |
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