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| 1 | Detail control strategies for topology optimization in architectural design and development显示文摘With the ability to generate forms with high efficiency and elegant geometry,topology optimization has been increasingly used in architectural and structural designs.However,the conventional topology optimization techniques aim at achieving the structurally most efficient solution without any potential for architects or designers to control the design details.This paper introduces three strategies based on Bi-directional Evolutionary Structural Optimization(BESO)method to artificially pre-design the topological optimized structures.These strategies have been successfully applied in the computational morphogenesis of various structures for solving practical design problems.The results demonstrate that the developed methodology can provide the designer with structurally efficient and topologically different solutions according to their proposed designs with multi-filter radii,multi-volume fractions,and multi-weighting coefficients.This work establishes a general approach to integrating objective topology optimization methods with subjective human design preferences,which has great potential for practical applications in architecture and engineering industry. | Xin Yan Dingwen Bao Yufang Zhou Yimin Xie Tong Cui | 2022 | Frontiers of Architectural Research2022,11,2: | 4 |
| 2 | Co-Expression of XIAP and Cyclin D1 Complex Correlates with a Poor Prognosis in Patients with Hepatocellular Carcinoma显示文摘 | Yufang Che Fei Ye Ruliang Xu Haitao Qing Xinying Wang Fei Yin Miao Cui David Burstein Bo Jiang David Y. Zhang | 2012 | The American Journal of Pathology2012,,5: | 1 |
| 3 | Apoptosis of circulating lymphocytes induced by whole body γ-irradiation and its mechanism显示文摘 | Cui Yufang Gao Yabing Yang Hong | 1999 | J Environ Pathol Toxicol Oncol1999,18,: | 1 |
| 4 | Real-time immunoassay of ferritin using surface Plasmon resonance biosensor 显示文摘 | Cui Xiaoqiang Yang Fan Sha Yufang | 2003 | Talanta2003,60,: | 1 |
| 5 | NCL-based mitochondrial-targeting fluorescent probe for the detection of Glutathione in living cells显示文摘Glutathione(GSH) plays a critical role in maintaining cellular redox homeostasis in biological system.Mitochondrion is a pivotal organelle for cellular aerobic respiration and its disorder is associated with impaired redox balance, leading to cell death. In this work, we designed and synthesized a non-invasive“off-on” mitochondrial-targeting fluorescent probe QZ for the detection of GSH in living cells. Based on the mechanism of native chemical ligation(NCL) and fluorescence resonance energy transfer(FRET), a rhodamine B derivative, QZ was prepared, by choosing aromatic thioester bond as the selective reaction site. QZ exhibited excellent detection capability for GSH over Cys and Hcy. Upon addition of GSH to QZ solution, a remarkably enhanced fluorescence was observed with a limit of detection of 2.98 μmol/L.Furthermore, QZ was found to possess the specific mitochondrial localization ability in cell imaging experiments. Moreover, with exogenous and endogenous stimulations, QZ could image GSH in living cells. | Tongxia Jin Mengyu Cui Dan Wu Weiping Zhu Yufang Xu Xuhong Qian | 2021 | Chinese Chemical Letters2021,32,12: | 1 |
| 6 | Molecular mechanism of damage and repair of mouse thymus lymphocytes induced by radiation显示文摘 | Cui Yufang Yang Hong Wu Shuxia | 2002 | CMJ2002,115,: | 1 |
| 7 | Robust Trajectory and Communication Design for Angle-Constrained Multi-UAV Communications in the Presence of Jammers显示文摘This paper studies a multi-unmanned aerial vehicle(UAV)enabled wireless communication system,where multiple UAVs are employed to communicate with a group of ground terminals(GTs)in the presence of potential jammers.We aim to maximize the throughput overall GTs by jointly optimizing the UAVs’trajectory,the GTs’scheduling and power allocation.Unlike most prior studies,we consider the UAVs’turning and climbing angle constraints,the UAVs’three-dimensional(3D)trajectory constraints,minimum UAV-to-UAV(U2U)distance constraint,and the GTs’transmit power requirements.However,the formulated problem is a mixed-integer non-convex problem and is intractable to work it out with conventional optimization methods.To tackle this difficulty,we propose an efficient robust iterative algorithm to decompose the original problem be three sub-problems and acquire the suboptimal solution via utilizing the block coordinate descent(BCD)method,successive convex approximation(SCA)technique,and S-procedure.Extensive simulation results show that our proposed robust iterative algorithm offers a substantial gain in the system performance compared with the benchmark algorithms. | Yufang Gao Yang Wu Zhichao Cui Wendong Yang Guojie Hu Shiming Xu | 2022 | China Communications2022,19,2: | 1 |
| 8 | SARS-CoV-2 immunity and functional recovery of COVID-19 patients 1-year after infection显示文摘The long-term immunity and functional recovery after SARS-CoV-2 infection have implications in preventive measures and patient quality of life.Here we analyzed a prospective cohort of 121 recovered COVID-19 patients from Xiangyang,China at 1-year after diagnosis.Among them,chemiluminescence immunoassay-based screening showed 99%(95%CI,98–100%)seroprevalence 10–12 months after infection,comparing to 0.8%(95%CI,0.7–0.9%)in the general population.Total anti-receptor-binding domain(RBD)antibodies remained stable since discharge,while anti-RBD IgG and neutralization levels decreased over time.A predictive model estimates 17%(95%CI,11–24%)and 87%(95%CI,80–92%)participants were still 50%protected against detectable and severe re-infection of WT SARS-CoV-2,respectively,while neutralization levels against B.1.1.7 and B.1.351 variants were significantly reduced.All non-severe patients showed normal chest CT and 21%reported COVID-19-related symptoms.In contrast,53%severe patients had abnormal chest CT,decreased pulmonary function or cardiac involvement and 79%were still symptomatic.Our findings suggest long-lasting immune protection after SARS-CoV-2 infection,while also highlight the risk of immune evasive variants and long-term consequences for COVID-19 survivors. | Yan Zhan Yufang Zhu Shanshan Wang Shijun Jia Yunling Gao Yingying Lu Caili Zhou Ran Liang Dingwen Sun Xiaobo Wang Zhibing Hou Qiaoqiao Hu Peng Du Hao Yu Chang Liu Miao Cui Gangling Tong Zhihua Zheng Yunsheng Xu Linyu Zhu Jin Cheng Feng Wu Yulan Zheng Peijun Liu Peng Hong | 2021 | Signal Transduction and Targeted Therapy2021,6,11: | 0 |
| 9 | Tuning coherent phonon dynamics in two-dimensional phenylethylammonium lead bromide perovskites显示文摘Organic-inorganic layered perovskites are two-dimensional quantum well layers in which the layers of lead halide octahedra are stacked between the organic cation layers.The packing geometry of the soft organic molecules and the stiff ionic crystals induce structural deformation of the inorganic octahedra,generating complex lattice dynamics.Especially,the dielectric confinement and ionic sublattice lead to strong coupling between the photogenerated excitons and the phonons from the polar lattice which intensively affects the properties for device applications.The anharmonicity and dynamic disorder from the organic cations participate in the relaxation dynamics coupled with excitations.However,a detailed understanding of this underlying mechanism remains obscure.This work investigates the electron–optical phonon coupling dynamics by employing ultrafast pump-probe transient absorption spectroscopy.The activated different optical phonon modes are observed via systematic studies of(PEA)_(2)PbBr_(4) perovskite films on the ultrafast lattice vibrational dynamics.The experimental results indicate that solvent engineering has a significant influence on lattice vibrational modes and coherent phonon dynamics.This work provides fresh insights into electron-optical phonon coupling for emergent optoelectronics development based on layered perovskites. | Minghuan Cui Chaochao Qin Zhongpo Zhou Yuanzhi Jiang Shichen Zhang Zeye Yuan Mingjian Yuan Kun Yu Yuhai Jiang Yufang Liu | 2023 | Nano Research2023,16,2: | 0 |