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| 1 | Fault plane parameters of Tancheng M81/2 earthquake on the basis of present-day seismological data显示文摘The great Tancheng earthquake of M81/2 occurred in 1668 was the largest seismic event ever recorded in history in eastern China.This study determines the fault geometry of this earthquake by inverting seismological data of present-day moderate-small earthquakes in the focal area.We relocated those earthquakes with the double-difference method and found focal mechanism solutions using gird test method.The inversion results are as follows:the strike is 21.6°,the dip angle is 89.5°,the slip angle is 170°,the fault length is about 160 km,the lower-boundary depth is about 32 km and the buried depth of upper boundary is about 4 km.This shows that the seismic fault is a NNE-trending upright right-lateral strike-slip fault and has cut through the crust.Moreover,the surface seismic fault,intensity distribution of the earthquake,earthquake-depth distribution and seismic-wave velocity profile in the focal area all verified our study result. | Cuiying Zhou Guiling Diao Jie Geng Yonghong Li Ping Xu Xinliang Hu Xiangdong Feng | 2010 | Earthquake Science2010，23，6： | 7 |
| 2 | Accelerated anaerobic dechlorination of DDT in slurry with Hydragric Acrisols using citric acid and anthraquinone-2,6-disulfonate(AQDS)显示文摘The application of electron donor and electron shuttle substances has a vital influence on electron transfer,thus may affect the reductive dechlorination of 1,1,1-trichoro-2,2-bis(p-chlorophenyl)ethane(DDT) in anaerobic reaction systems.To evaluate the roles of citric acid and anthraquinone-2,6-disulfonate(AQDS) in accelerating the reductive dechlorination of DDT in Hydragric Acrisols that contain abundant iron oxide,a batch anaerobic incubation experiment was conducted in a slurry system with four treatments of(1) control,(2) citric acid,(3) AQDS,and(4) citric acid + AQDS.Results showed that DDT residues decreased by 78.93%–92.11% of the initial quantities after 20 days of incubation,and 1,1-dichloro-2,2-bis(4-chlorophenyl)-ethane(DDD) was the dominant metabolite.The application of citric acid accelerated DDT dechlorination slightly in the first 8 days,while the methanogenesis rate increased quickly,and then the acceleration effect improved after the 8th day while the methanogenesis rate decreased.The amendment by AQDS decreased the Eh value of the reaction system and accelerated microbial reduction of Fe(III) oxides to generate Fe(II),which was an efficient electron donor,thus enhancing the reductive dechlorination rate of DDT.The addition of citric acid + AQDS was most efficient in stimulating DDT dechlorination,but no significant interaction between citric acid and AQDS on DDT dechlorination was observed.The results will be of great significance for developing an efficient in situ remediation strategy for DDT-contaminated sites. | Cuiying Liu Xianghua Xu Jianling Fan | 2015 | Journal of Environmental Sciences2015，27，12： | 5 |
| 3 | BRCA1 affects global DNA methylation through regulation of DNMT1显示文摘在 CpG 岛的全球 DNA hypomethylation 结合了本地 hypermethylation 是为乳癌的一个特点,然而,位于这个变化下面的机制留下逃犯。在这研究,我们证明 DNMT1,编码 methylation 维护酶,是 BRCA1 的一个 transcriptional 目标。BRCA1 通过一个潜在的 OCT1 地点和绑定绑在 DNMT1 基因的倡导者为维持 transcriptional 被要求在老鼠和人的房间的倡导者的活跃配置。我们进一步证明 BRCA1 的那损害功能在在 premaligant 阶段在一个 BRCA1 变异的老鼠模型检验的纸巾的几种类型导致全球 DNA hypomethylation,印的 genomic 的损失,和一种开的染色质配置。BRCA1 缺乏也与几 protooncogenes 的显著地增加的表达式层次被联系,包括 c-Fos,哈地岬,和 c-Myc,与在肿瘤的一个更高的表达式,当时乳房的上皮的房间显示了的 premalignant 在肿瘤和控制之间的一个中间的状态。在人的临床的样品,有 DNMT1 的减少的层次的 BRCA1 相互关联的减少的表示,和 CpG 岛的减少的 methylation。因此, BRCA1 通过断然调整 DNMT1 表示阻止全球 DNA hypomethylation,并且这为联系 BRCA1 的乳癌形成提供机制之一。 | Vivek Shukla Xavier Coumoul Tyler Lahusen Rui-Hong Wang Xiaoling Xu Athanassios Vassilopoulos Cuiying Xiao Mi-Hye Lee Yan-Gao Man Mutsuko Ouchi Toru Ouchi Chu-Xia Deng | 2010 | Cell Research2010，20，11： | 5 |
| 4 | Linkage map and QTL mapping of red flesh locus in apple using a R1R1×R6R6 population显示文摘The red flesh in apple fruit is a desired trait by consumers and it is associated to the anthocyanin content,which is mainly controlled by MdMYB10 with a R6 promoter.In this study,a high-density linkage group was constructed using the‘Fuji’x‘Red3’population which contained homozygous alleles R1R1 and R6R6,respectively.The linkage group consists of 7630 SNPs along 17 linkage groups,spanning 2270.21 cM,with an average density of 0.30 cM permarker.The cyanidin-3-galactoside concentration was used as the phenotypic data in QTL analysis.Moreover,one QTL peak which was flaked by two markers,marker2187260 to marker2173766,with LOD scores of 4.49 was detected.This QTL ranged from 0 to 40.79 cM on the top of linkage group(LG16).In addition one candidate molecular marker(marker2175442)in this QTL was identified,which was significant correlated with the flesh cyanidin-3-galactoside concentration.These genetic findings enrich the breeding basis of fruit flesh coloration in apple. | Chengquan Yang Guangya Sha Tao Wei Baiquan Ma Cuiying Li Pengmin Li Yangjun Zou Lingfei Xu Fengwang Ma | 2021 | Horticultural Plant Journal2021，7，5： | 4 |
| 5 | Impaired DNA Damage Response, Genome Instability, and Tumorigenesis in SIRT1 Mutant Mice显示文摘 | Rui-Hong Wang Kundan Sengupta Cuiling Li Hyun-Seok Kim Liu Cao Cuiying Xiao Sangsoo Kim Xiaoling Xu Yin Zheng Beverly Chilton Rong Jia Zhi-Ming Zheng Ettore Appella Xin Wei Wang Thomas Ried Chu-Xia Deng | 2008 | Cancer Cell2008，，4： | 1 |
| 6 | Interplay among BRCA1, SIRT1, and Survivin during BRCA1-Associated Tumorigenesis显示文摘 | Rui-Hong Wang Yin Zheng Hyun-Seok Kim Xiaoling Xu Liu Cao Tyler Lahusen Mi-Hye Lee Cuiying Xiao Athanassios Vassilopoulos Weiping Chen Kevin Gardner Yan-Gao Man Mien-Chie Hung Toren Finkel Chu-Xia Deng | 2008 | Molecular Cell2008，，1： | 1 |
| 7 | Hepatic-Specific Disruption of SIRT6 in Mice Results in Fatty Liver Formation Due to Enhanced Glycolysis and Triglyceride Synthesis显示文摘 | Hyun-Seok Kim Cuiying Xiao Rui-Hong Wang Tyler Lahusen Xiaoling Xu Athanassios Vassilopoulos Guelaguetza Vazquez-Ortiz Won-Il Jeong Ogyi Park Sung Hwan Ki Bin Gao Chu-Xia Deng | 2010 | Cell Metabolism2010，，3： | 1 |
| 8 | Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance显示文摘 | Wang Rui-Hong Kim Hyun-Seok Xiao Cuiying Xu Xiaoling Gavrilova Oksana Deng Chu-Xia | 2011 | Journal of Clinical Investigation2011，，11： | 1 |
| 9 | Dielectric Breakdown Model for an Electrically Semi-Permeable Penny-Shaped Crack in Three-Dimensional Piezoelectric Media显示文摘The dielectric breakdown(DB) model for a penny-shaped crack under a semipermeable boundary condition in a three-dimensional piezoelectric medium is studied.An approximate analytical solution is derived by using the boundary integral equation with extended displacement discontinuity,and the corresponding boundary element method with double iterative approaches is developed to analyze the semi-permeable crack.The effect of electric boundary conditions on crack faces is discussed on the basis of DB model.By comparing the DB model with the polarization saturation(PS) model for different piezoelectric materials,some interesting phenomena related to the electric yielding zone and local J-integral are observed. | Minghao Zhao Huayang Dang Guangtao Xu Cuiying Fan | 2016 | Acta Mechanica Solida Sinica2016，29，5： | 1 |
| 10 | Impaired DNA Damage Response, Genome Instability, and Tumorigenesis in SIRT1 Mutant Mice显示文摘 | Rui-Hong Wang Kundan Sengupta Cuiling Li Hyun-Seok Kim Liu Cao Cuiying Xiao Sangsoo Kim Xiaoling Xu Yin Zheng Beverly Chilton Rong Jia Zhi-Ming Zheng Ettore Appella Xin Wei Wang Thomas Ried Chu-Xia Deng | 2008 | Cancer Cell2008，，4： | 1 |
| 11 | Effect of enzymatic extraction conditions on the yield and the polymerization degree of procyanidins显示文摘Grape seeds are rich sources of procyanidin(PCs)known for potential health benefi ts.In this study,PCs were extracted from defatted grape seeds by enzymatic method in which pectinase and cellulase were used.The enzyme extraction process was further optimized by single factor experiment and response surface methodology.The optimal conditions were as follows:ethanol concentration of 70%,extraction time of 70 min,extraction temperature of 35℃,liquid/solid ratio of 103:1(mL/g),pectinase/cellulase ratio of 1:1,enzyme/solid ratio of 1:314 w/w.Under the above conditions,the extraction yields and mean degree of polymerisation(mDP)of PCs reached 47.18 mg/g dry material weight and 11.2,respectively.Compared with other extraction methods,enzyme extraction can obtain PCs with higher yield and lower mDP.According to the antioxidant activity test,PCs extracts with lower mDP showed better ability to clear 1,1-Diphenyl-2-picrylhydrazyl radical(DPPH).Enzymatic extraction was an effi cient method to obtain oligomeric procyanidin which has stronger antioxidant activity. | Shijie Sun Xiong Chen Zhaoyang Pei Lulu Xu Cuiying Qin Jing Han | 2020 | Journal of Polyphenols2020，2，1： | 0 |
| 12 | Visualization of the Oncolytic Alphavirus M1 Life Cycle in Cancer Cells显示文摘Oncolytic alphavirus M1 has been shown to selectively target and kill cancer cells,but cytopathic morphologies induced by M1 virus and the life cycle of the M1 strain in cancer cells remain unclear.Here,we study the key stages of M1 virus infection and replication in the M1 virus-sensitive HepG2 liver cancer cell line by transmission electron microscopy,specifically examining viral entry,assembly,maturation and release.We found that M1 virus induces vacuolization of cancer cells during infection and ultimately nuclear marginalization,a typical indicator of apoptosis.Specifically,our results suggest that the endoplasmic reticulum participates in the assembly of nucleocapsids.In the early and late stage of infection,three kinds of special cytopathic vacuoles are formed and appear to be involved in the replication,maturation and release of the virus.Taken together,our data displayed the process of M1 virus infection of tumor cells and provide the structural basis for the study of M1 virus-host interactions. | Jia Dan Lin Nie Xudong Jia Cuiying Xu Jing Cai Yuan Lin Jun Hu Wenbo Zhu Yinyin Li Dong Chen Ying Liu Cheng Hu Guangmei Yan Jiankai Liang Qinfen Zhang | 2021 | Virologica Sinica2021，36，4： | 0 |
| 13 | Correction to:Visualization of the Oncolytic Alphavirus M1 Life Cycle in Cancer Cells显示文摘Correction to:Virologica Sinica(2021)http://gffzzd3cc09b8251d45dfsvwwnqv6pwuu56fxn.ffgz.tsg.suse.edu.cn/10.1007/s12250-020-00339-7 In the original version of Fig.6,published on January 22,2021,the names of image panels(row 2 to row 5)were mislabeled during figure layout.The corrected figure is shown below.The original article has been corrected. | Jia Dan Lin Nie Xudong Jia Cuiying Xu Jing Cai Yuan Lin Jun Hu Wenbo Zhu Yinyin Li Dong Chen Ying Liu Cheng Hu Guangmei Yan Jiankai Liang Qinfen Zhang | 2021 | Virologica Sinica2021，36，4： | 0 |
| 14 | Sound propagation in glass-ceramic显示文摘The acoustic theory of the suspensions is applied to the studyof acoustic proper ties of glass-ceramic.The relations between thesound speed and the sound attenuation with the crystallinity inglass-ceramic are derived.The theoretical results are verified by theultrasonic experiments. | ZHENG Hong ZHAO Mingzhou XU Yongchen(Pohl Institute of Solid State Physics, Tongji University)FENG Cuiying(Measure & Analysis Center, Tongji University) | 1990 | Chinese Journal of Acoustics1990，9，4： | 0 |
| 15 | Structural insights into ligand recognition and selectivity of somatostatin receptors显示文摘Somatostatin receptors(SSTRs)play versatile roles in inhibiting the secretion of multiple hormones such as growth hormone and thyroid-stimulating hormone,and thus are considered as targets for treating multiple tumors.Despite great progress made in therapeutic development against this diverse receptor family,drugs that target SSTRs still show limited efficacy with preferential binding affinity and conspicuous side-effects.Here,we report five structures of SSTR2 and SSTR4 in different states,including two crystal structures of SSTR2 in complex with a selective peptide antagonist and a non-peptide agonist,respectively,a cryo-electron microscopy(cryo-EM)structure of Gi1-bound SSTR2 in the presence of the endogenous ligand SST-14,as well as two cryo-EM structures of Gi1-bound SSTR4 in complex with SST-14 and a small-molecule agonist J-2156,respectively.By comparison of the SSTR structures in different states,molecular mechanisms of agonism and antagonism were illustrated.Together with computational and functional analyses,the key determinants responsible for ligand recognition and selectivity of different SSTR subtypes and multiform binding modes of peptide and non-peptide ligands were identified.Insights gained in this study will help uncover ligand selectivity of various SSTRs and accelerate the development of new molecules with better efficacy by targeting SSTRs. | Wenli Zhao Shuo Han Na Qiu Wenbo Feng Mengjie Lu Wenru Zhang Mu Wang Qingtong Zhou Shutian Chen Wei Xu Juan Du Xiaojing Chu Cuiying Yi Antao Dai Liaoyuan Hu Michelle YShen Yaping Sun Qing Zhang Yingli Ma Wenge Zhong Dehua Yang Ming-Wei Wang Beili Wu Qiang Zhao | 2022 | Cell Research2022，32，8： | 0 |
| 16 | Enhanced anaerobic degradation of hexachlorobenzene in a Hydragric Acrisol using humic acid and urea显示文摘Humic substances acting as an electron shuttle and nitrogen transformation process influence remarkably the electron transfer in anaerobic reaction systems and thus may affect the reductive dechlorination of hexachlorobenzene(HCB). In order to develop an efficient agricultural strategy for the remediation of organochlorine-contaminated soils, a batch incubation experiment was conducted to study the effects of humic acid, urea, and their interaction on the reductive dechlorination of HCB in a Hydragric Acrisol with high iron oxide content. After 44 d of anaerobic incubation, the five treatments, sterile control,control, humic acid, urea, and humic acid + urea decreased HCB residues by 28.8%, 47.8%, 64.7%, 57.8%, and 71.3%, respectively. The amendment of humic acid or urea significantly decreased soil Eh values and accelerated Fe(Ⅲ) reduction to Fe(Ⅱ), thus promoting markedly reductive dechlorination of HCB. Humic acid had a larger dechlorination effect than urea. Since there was a synergistic interaction between humic acid and urea that accelerated HCB dechlorination, the treatment having both amendments together was the most efficient for HCB dechlorination. The results showed that the combination of NH4^(+)_(-)N supplied by a fertilizer and humic substance is a feasible strategy for the remediation of organochlorine-contaminated soils with abundant iron oxide. | Cuiying LIU Jianling FAN Xianghua xu Yu Wu | 2021 | Pedosphere2021，31，1： | 0 |
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