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| 1 | Human mesenchymal stem cells overexpressing pigment epitheliumderived factor inhibit hepatocellular carcinoma in nude mice(摘要)显示文摘 | Gao, Y Yao, A Zhang, W Lu, S Yu, Y Deng, L Yin, A Xia, Y Sun, B Wang, X | 2010 | 南京医科大学学报(自然科学版)2010，30，8： | 25 |
| 2 | An ABA-mimicking ligand that reduces water loss and promotes drought resistance in plants显示文摘Abscisic 酸(骆驼毛的织物) 是最重要的荷尔蒙让植物抵抗干旱和另外的不能生活的压力。骆驼毛的织物直接绑在骆驼毛的织物受体的 PYR/PYL 家庭,导致类型 2C 磷酸酶(PP2C ) 和下游的骆驼毛的织物发信号的激活的抑制。骆驼毛的织物由小分子发信号的干预能帮助植物克服象干旱,寒冷和土壤咸度那样的不能生活的压力,这被想象。然而,由植物酶的化学不稳定性和快速的分解代谢限制骆驼毛的织物本身的实际申请。这里,我们报导一件小分子骆驼毛的织物的鉴定模仿(AM1 ) 那充当骆驼毛的织物受体的家庭的多重成员的有势力使活跃之物。在 Arabidopsis, AM1 激活高度类似于由骆驼毛的织物导致了那的一个基因网络。有 AM1 的处理禁止种子萌芽,阻止叶水损失,并且支持干旱抵抗。我们与 PYL2 骆驼毛的织物受体和 HAB1 PP2C 在建筑群解决了 AM1 的水晶结构,它表明 AM1 调停交往的 gate-latch-lock 网络,在骆驼毛的织物界限 receptor/PP2C 建筑群被保存的一个结构的特征。一起,这些结果证明一件单个小分子骆驼毛的织物模仿能激活多重骆驼毛的织物受体并且保护植物免受水损失和干旱应力的伤害。而且, AM1 复杂水晶结构为设计 ABA-mimicking 小分子的下一代提供一个结构的基础。 | Minjie Cao Xue Liu Yan Zhang Xiaoqian Xue X EdwardZhou Karsten Melcher Pan Gao Fuxing Wang Liang Zeng Yang Zhao Pan Deng Dafang Zhong Jian-Kang Zhu H Eric Xu Yong Xu | 2013 | Cell Research2013，23，8： | 17 |
| 3 | Gastroesophageal reflux: the features in elderlypatients显示文摘AIM To compare the features ofgastroesophageal reflux disease between elderlyand younger patients.METHODS Twenty-four hour pH-monitoring andendoscopy were P6rformed for the 66 elderlypatients with typical gastroesophageaI refluxsymptoms, and the results were compared with112 symptomatic younger patients.RESULTS The results of 24-h pH-monitoringand endoscopy showed that the elderly patientshad pathological reflux and reflux esophagitismore frequently than the younger patients.P6rcentage time with pH< 4 in elderly patientswith reflux esophagitis was 32.5% in 24 hours,as compared with 12.9% in the younger patientswith reflux esophagitis (P < 0 .05 ). The elderlypatients with reflux esophagitis have longerP6riOds of acid reflux in both upright and Supinepositions than the younger patients. Endoscopyshowed that 20 .8% of elderIy patients had grade Ⅲ / Ⅳ esophagitis, whereas only 3.4% ofyounger patients had grade Ⅲ/ Ⅳ esophagitis(P < 0.002 ). Percentages of grades Ⅰ /Ⅱesophagitis in the two groups were 12.5% and26. 5%, respectiveIy (P< 0. 002 ).CONCLUSION Elderly patients, as comparedwith younger patients, have more severegastroesophageal reflux and esophageal lesions.The incompetence of lower esophageal sphincter and the presence of hiataI hernia may beimportant factors leading to the difference in incidence and severity of reflux esophagitisbetween elderly and younger patients. | Huang X Zhu HM Deng CZ Porro GB Sangaletti O Pace F | 1999 | World Journal of Gastroenterology1999，5，5： | 12 |
| 4 | 柑桔黄龙病的鉴定和柯赫氏定理(英文)显示文摘黄龙(梢)病被认为是世界柑橘生产上的毁灭性病害已超过一个世纪,但该病害的病原学至今还没有清晰地建立起来。根据16S rRNA基因序列分析,一组被称为'Candidatus Liberibacter species'的难培养细菌被认为与黄龙病相关。然而,要确定'Ca.Liberibacter spp.'是黄龙病病原的柯赫氏定理并没有真正完成。令我们担忧的是,近年来有些文献频频指出'Ca.Liberibacter spp.'是黄龙病的病原,其实该细菌与柑橘寄主的直接病理反应还没有完全确定。我们建议,在黄龙病病原学清楚之前,文献报道在这方面需要有准确的阐述。 | Chen J Deng X Civerolo E L Lee R F Jones J B Zhou C Hartung J S Manjunath K L Brlansky R H | 2011 | 植物病理学报2011，41，2： | 10 |
| 5 | 大气细颗粒物可通过长链非编码RNA途径促进肺癌细胞的迁移侵袭显示文摘长期暴露于大气细颗粒物(PM2.5)可能造成或加剧包括肺癌在内的多种疾病,但机制尚未完全清楚。新发现的长链非编码RNA虽然不能编码蛋白质,却能调控多种生命活动并参与肿瘤的发生发展。研究者将肺腺癌A549细胞暴露于PM2.5混悬的DMEM细胞培养基,构建肺癌细胞暴露PM2.5模型;实时荧光定量PCR检测长链非编码RNA loc146880的表达水平; | 李欣洋 张遵真 Deng X Feng N Zheng M | 2017 | 环境卫生学杂志2017，7，5： | 6 |
| 6 | 新型冠状病毒感染合并高血压住院患者使用肾素血管紧张素系统阻断剂与病重及死亡风险的相关性显示文摘目前,缺乏关于新型冠状病毒疾病(coronavirus disease 2019,COVID-19)合并高血压患者在住院期间使用血管紧张素转换酶抑制剂(angiotensin converting enzyme inhibitor,ACEI)或血管紧张素受体拮抗剂(angiotensin receptor blocker,ARB)是否增加病重或死亡风险的数据。本研究回顾性纳入2020年1月15日至3月15日于武汉中心医院住院的COVID-19患者1 178例。 | 袁源(摘译) 叶鹏(审校) Li J Wang X Chen J Zhang H Deng A | 2020 | 中华高血压杂志2020，28，6： | 6 |
| 7 | Auxiliary principle and iterative algorithms for generalized set-valued strongly nonlinear mixed variational-like inequalities显示文摘 | Huang N J Deng C X | 2001 | J Math Anal Appl2001，256，： | 2 |
| 8 | Overview to the Hard X-ray Modulation Telescope (Insight-HXMT) Satellite显示文摘As China’s first X-ray astronomical satellite, the Hard X-ray Modulation Telescope (HXMT), which was dubbed as Insight-HXMT after the launch on June 15, 2017, is a wide-band(1-250 ke V) slat-collimator-based X-ray astronomy satellite with the capability of all-sky monitoring in 0.2-3 Me V. It was designed to perform pointing, scanning and gamma-ray burst(GRB)observations and, based on the Direct Demodulation Method (DDM), the image of the scanned sky region can be reconstructed.Here we give an overview of the mission and its progresses, including payload, core sciences, ground calibration/facility, ground segment, data archive, software, in-orbit performance, calibration, background model, observations and some preliminary results. | Shuang-Nan Zhang TiPei Li FangJun Lu LiMing Song YuPeng X u CongZhan Liu Yong Chen XueLei Cao QingCui Bu Zhi Chang Gang Chen Li Chen TianXiang Chen YiBao Chen YuPeng Chen Wei Cui WeiWei Cui JingKang Deng YongWei Dong Yuan Yuan Du MinXue Fu GuanHua Gao He Gao Min Gao MingYu Ge YuDong Gu Ju Guan Can Gungor ChengCheng Guo DaWei Han Wei Hu Yue Huang Jia Huo ShuMei Jia LuHua Jiang WeiChun Jiang Jing Jin YongJie Jin Bing Li ChengKui Li Gang Li MaoShun Li Wei Li Xian Li XiaoBo Li XuFang Li YanGuo Li ZiJian Li ZhengWei Li XiaoHua Liang JinYuan Liao GuoQing Liu HongWei Liu ShaoZhen Liu XiaoJing Liu Yuan Liu YiNong Liu Bo Lu XueFeng Lu Tao Luo Xiang Ma Bin Meng Yi Nang JianYin Nie Ge Ou JinLu Qu Na Sai RenCheng Shang GuoHong Shen Liang Sun Ying Tan Lian Tao YouLi Tuo Chen Wang ChunQin Wang GuoFeng Wang HuanYu Wang Juan Wang WenShuai Wang YuSa Wang XiangYang Wen BaiYang Wu BoBing Wu Mei Wu GuangCheng Xiao ShaoLin Xiong LinLi Yan JiaWei Yang Sheng Yang YanJi Yang QiBin Yi Bin Yuan AiMei Zhang ChunLei Zhang ChengMo Zhang Fan Zhang HongMei Zhang Juan Zhang Qiang Zhang ShenYi Zhangs Shu Zhang Tong Zhang WanChang Zhang Wei Zhang WenZhao Zhang Yi Zhang YiFei Zhang YongJie Zhang Yue Zhang Zhao Zhang Zhi Zhang ZiLiang Zhang HaiSheng Zhao XiaoFan Zhao ShiJie Zheng JianFeng Zhou YuXuan Zhu Yue Zhu RenLin Zhuang | 2020 | Science China(Physics,Mechanics & Astronomy)2020，63，4： | 2 |
| 9 | Broadly cross-reactive mimotope of hypervariable region 1 of hepatitis C virus derived from DNA shuffling and screened by phage display library显示文摘 | Zhang X X Deng Q Zhang S Y | 2002 | Biotechnol Appl Biochem2002，35，3： | 2 |
| 10 | Pathogenetic factors affecting gastroesophageal refluxin patients with esophagitis and concomitant duodenal ulcer:a multivariate analysis显示文摘Pathogeneticfactorsafectinggastroesophagealrefluxinpatientswithesophagitisandconcomitantduodenalulcer:amultivariateanalysisZH... | Zhu, HM Huang, X Deng, CZ Porro, GP Pace, F Sangaletti, O | 1998 | World Journal of Gastroenterology1998，4，2： | 2 |
| 11 | A novel Ru-B/SiO_2 amorphous catalyst used in benzene-selective hydrogenation显示文摘 | Xie S H Qiao M H Li H X Wang W J Deng J-F | | 0，，： | 2 |
| 12 | A dynamic system approach to speech enhancement using the H∞ filtering algorithm显示文摘 | SHEN X M DENG L | 1999 | IEEE Trans on Speech and Audio Processing1999，7，4： | 1 |
| 13 | Intergeneric somatic hybrid plants fromprotoplast fusion of Fortunella crassifolia Meiwa with Citrus sinensis ‘Valencia' 显示文摘 | Deng X X Grosser J W Gimtter F G Jr | 1991 | Scientia Hort1991，49，： | 1 |
| 14 | Multifrequency large amplitude pulse voltammetry: A novel electrochemical method for electronic tongue显示文摘 | Tian S Y Deng S P Chen Z X | 2007 | Sensor and Actuator B: Chem2007，123，2： | 1 |
| 15 | Mierqstructure and mechanical behavior of porous sintered steels 显示文摘 | Chawla N Deng X | 2005 | Materials Science and Engineering A2005，390，12： | 1 |
| 16 | 2D structure with rectangular grids woven by coordination chains and pseudo-metal wires 显示文摘 | ZHANG H X KANG B S DENG L R | 2001 | Inorg Chem Commun2001，4，： | 1 |
| 17 | Chromosomal polymorphism of mandarin vole,Microtus mandariaus(Rodentia)显示文摘 | WANG J X ZHAO X F DENG Y | 2003 | Hereditas2003，135，1： | 1 |
| 18 | Generalized R -KKM theorems in topological space and their applications显示文摘 | DENG L XIA X | 2003 | J Math Anal App2003，285，2： | 1 |
| 19 | Research of thermal stability of nano - copper particles 显示文摘 | Liu W M Deng X Y Zhang Z K | 2004 | PTCA (Part A: Physical Testing)2004，40，2： | 1 |
| 20 | Immobilization of trypsin on superparamagnetic nanoparticles for rapid and effective proteolysis显示文摘 | Li Y Xu X Deng C | 2007 | J Proteome Res2007，6，9： | 1 |
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