|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Mycophenolate mofetil for drug-induced vanishing bile duct syndrome显示文摘Amoxicillin/clavulanate is associated with liver injury, mostly of a cholestatic pattern. While outcomes are usually benign, progression to cirrhosis and death has been reported. The role of immunosuppressive therapy for patients with a protracted course is unclear. We report the case of an elderly patient who developed prolonged cholestasis secondary to amoxicillin/clavulanate. Vanishing bile duct syndrome was confirmed by sequential liver biopsies. The patient responded to prednisone treatment, but could not be weaned off corticosteroids, even when azathioprine was added. Complete withdrawal of both prednisone and azathioprine was possible by using mycophenolate mofetil, an inosine monophosphate dehydrogenase inhibitor. Sustained remission has been maintained for more than 3 years with low-dose mycophenolate mofetil. | S Simona Jakab A Brian West Dennis M Meighan Robert S Brown Jr William B Hale | 2007 | World Journal of Gastroenterology2007，13，45： | 8 |
| 2 | Land cover changes and fragmentation in mountain neotropical ecosystems of Oaxaca, Mexico under community forest management显示文摘Changes in land cover have a direct impact on forest ecosystem goods and services. In this study, changes in land cover in Sierra de Juarez–Oaxaca ecosystems were estimated using a consistent processing of Landsat images and OBIA methodology. Additionally, landscape analyses using FRAGSTAT were conducted. In 2014, Sierra de Juarez–Oaxaca was covered by approximately 84% of forests, mainly pine-oak and cloud forests. After extensive deforestation until 2001, this trend was reversed and the forest cover surface area in 2014 was slightly higher than in 1979. The comparison of the landscape structure of the forested and agricultural lands suggests an increase in habitat heterogeneity. However, interspersion and juxtaposition indices, showing the patch shape by patch area and perimeter, were similar throughout the study period(1979–2014). Social and economic drivers can explain this situation: namely, community organization, forest enterprises, payment for ecosystem services programs, and changes of agricultural activity. Communities in the Sierra of Oaxaca have reforested degraded lands, created community forest enterprises, and preserved the forest under conservation schemes like those proposed by the Mexican payment for ecosystem services programs. However, their sustainable management faces internal challenges and has become highly dependent on political and institutional decisions beyond their control. | Rafael M~a Navarro Cerrillo Dennis J.Esteves Vieira Susana Ochoa-Gaona Bernardus H.J.de Jong M~a del Mar Delgado Serrano | 2019 | Journal of Forestry Research2019，30，1： | 4 |
| 3 | 利用抗高血压药相关的遗传变异发现其潜在的功效和副作用显示文摘通过研究药物靶蛋白基因的自然变异可以了解药物的功效。本研究旨在利用这种方法探索抗高血压药的潜在副作用和再利用潜力。研究者首先确定了血管紧张素转换酶抑制剂(angiotensin converting enzyme inhibitor,ACEI)、β受体阻滞剂和钙拮抗剂的合适代表基因。 | 刘青(译) 叶鹏(校) Gill D Georgakis MK Koskeridis F Jiang L Feng Q Wei WQ Theodoratou E Elliott P Denny JC Malik R Evangelou E Dehghan A Dichgans M Tzoulaki I | 2019 | 中华高血压杂志2019，0，9： | 3 |
| 4 | Epistaxis in end stage liver disease masquerading as severe upper gastrointestinal hemorrhage显示文摘AIM:To describe the prevalence,diagnosis,treatment,and outcomes of end stage liver disease(ESLD) patients with severe epistaxis thought to be severe upper gastrointestinal hemorrhage(UGIH).METHODS:This observational single center study included all consecutive patients with ESLD and epistaxis identified from consecutive subjects hospitalized with suspected UGIH and prospectively enrolled in our databases of severe UGIH between 1998 and 2011.RESULTS:A total of 1249 patients were registered for severe UGIH in the data basis,461(36.9%) were cirrhotics. Epistaxis rather than UGIH was the bleeding source in 20 patients. All patients had severe coagulopathy. Epistaxis was initially controlled in all cases. Fifteen(75%) subjects required posterior nasal packing and 2(10%) embolization in addition to correction of coagulopathy. Five(25%) patients died in the hospital,12(60%) received orthotopic liver transplantation(OLT),and 3(15%) were discharged without OLT. The mortality rate was 63% in patients without OLT.CONCLUSION:Severe epistaxis in patients with ESLD is(1) a diagnosis of exclusion that requires upper endoscopy to exclude severe UGIH;and(2) associated with a high mortality rate in patients not receiving OLT. | Marine Camus Dennis M Jensen Jason D Matthews Gordon V Ohning Thomas O Kovacs Rome Jutabha Kevin A Ghassemi Gustavo A Machicado Gareth S Dulai | 2014 | World Journal of Gastroenterology2014，20，38： | 3 |
| 5 | International corporate entrepreneurship and firm performance显示文摘 | Shaker A Zahra Dennis M Garvis | 2000 | Journal of Business Venturing2000，，5： | 3 |
| 6 | Precision atomic gravimeter based on Bragg diffraction显示文摘 | P A Altin M T Johnsson V Negnevitsky G R Dennis R P Anderson J E Debs S S Szigeti K S Hardman S Bennetts G D McDonald L D Turner J D Close N P Robins | 2013 | New Journal of Physics2013，，2： | 2 |
| 7 | Survival after inflammatory bowel disease-associated colorectal cancer in the Colon Cancer Family Registry显示文摘AIM: To investigate the survival of individuals with colorectal cancer (CRC) with inflammatory bowel disease (IBD-associated CRC) compared to that of individuals without IBD diagnosed with CRC. METHODS: Epidemiologic, clinical, and follow-up data were obtained from the Colon Cancer Family Registry (Colon CFR). IBD-associated cases were identified from self-report of physician diagnosis. For a subset of participants, medical records were examined to confirm self-report of IBD. Cox proportional hazards regression was applied to estimate adjusted hazard ratios (aHR) and 95%CI of mortality, comparing IBD-associated to non-IBD-associated CRC, adjusted for age at CRC diagnosis, sex, Colon CFR phase, and number of prior endoscopies. Following imputation to complete CRC stage information, adjustment for CRC stage was examined. RESULTS: A total of 7202 CRC cases, including 250 cases of IBD-associated CRC, were analyzed. Over a twelve year follow-up period following CRC diagnosis, 2013 and 74 deaths occurred among non-IBD associated CRC and IBD-associated CRC patients, respectively. The difference in survival between IBD-associated and non-IBD CRC cases was not statistically significant (aHR = 1.08; 95%CI: 0.85-1.36). However, the assumption of proportional hazards necessary for valid inference from Cox regression was not met over the entire follow-up period, and we therefore limited analyses to within five years after CRC diagnosis when the assumption of proportional hazards was met. Over this period, there was evidence of worse prognosis for IBD-associated CRC (aHR = 1.36; 95%CI: 1.05-1.76). Results were similar when adjusted for CRC stage, or restricted to IBD confirmed in medical records. CONCLUSION: These results support the hypothesis that IBD-associated CRC has a worse prognosis than non-IBD-associated CRC. | Scott V Adams Dennis J Ahnen John A Baron Peter T Campbell Steven Gallinger William M Grady Loic LeMarchand Noralane M Lindor John D Potter Polly A Newcomb | 2013 | World Journal of Gastroenterology2013，19，21： | 2 |
| 8 | Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR1 genes and pharmacokinetics ofthe calcineurin inhibitors cyclosporine and tacrolimus显示文摘 | DENNIS A HCSSELINK M D | 2003 | Clin Pharnuwol Ther2003，74，： | 1 |
| 9 | Rubber elongation by farnesyl pyrophosphate synthases involves a novel switch in enzymes tereospecificity 显示文摘 | LIGHT D R LAZARUS R A DENNIS M S | 1989 | The Journal of Biological Chemistry1989，264，18： | 1 |
| 10 | The CYP88A cytochrome P450,ent-kaurenoic acidoxidase,catalyzes three steps of gibberellin biosynthesis pathway显示文摘 | HELLIWELL C A CHANDLER P M POOLE A DENNIS E S PEACOCK W J | 2001 | PNAS2001，98，4： | 1 |
| 11 | Study of D-dimer levels using two different immunoturbidometric assays at different stage of pregnancy 显示文摘 | KHALAFALLAH AA MORSE M DENNIS A | 2007 | Journal of Thrombosis and Haemostasis2007，5，2： | 1 |
| 12 | Needle biopsy techniques显示文摘 | Parker S H Stavros A T Dennis M A | 1995 | Radiol Clin North Am1995，33，6： | 1 |
| 13 | Pandemic (H1N1) 2009 influenza显示文摘 | Patel M Dennis A Flutter C | 2010 | Br J Anaesth2010，104，12： | 1 |
| 14 | Synthesis of a fluorescent derivatizatizing reagent 6-aminoquinolyl-N-hydroxysuccinimidyl carbamate and its application for the analysis of hydrolysate amino acids via high-performance liquid chromatography显示文摘 | Steven A C Dennis P M | 1993 | Anal Biochem1993，211，： | 1 |
| 15 | Rickettsia-like organisms in the blue-eyed plecostomus,Pqnaque suttoni 显示文摘 | Dennis P M Lewbart G A | 1995 | J Fish Dis1995，18，： | 1 |
| 16 | Initial clinical results of linac-basedstereoactic radiosurgery and stereotactic radiotherapy for pituitaryadenomas显示文摘 | Michihide M Dennis C Eben A | 1998 | Int J Radiation Oncology Biol Phys1998，42，3： | 1 |
| 17 | Inactivation of multiple viru- lence genes reduces the ability of Pseudomonas sdanacearum to cause wilt symptoms显示文摘 | Denny T P Carney B F Schell M A | 1990 | Molecular Plant Microbiology Interac- tion1990，3，5： | 1 |
| 18 | Precision and bias of target controlled propofol infusion for sedation显示文摘 | Frolich M A Dennis D M Shuster J A | 2005 | Br J Anaesth2005，94，4： | 1 |
| 19 | Bovine citrullinaemia traced to the sire of Linmack Kriss King显示文摘 | HEALY P J DENNIS J A CAMILLERI L M | 1991 | Aust Vet J1991，68，： | 1 |
| 20 | Comparison between microwave and conventional sintering of WC/Co composites 显示文摘 | BREVAL E CHENG J P AGRAWAL D K GIGL P DENNIS M ROY R PAPWORTH A J | 2005 | Materials Science and Engineering A2005，391，12： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员