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| 1 | Nuclear Aurora kinase A switches m^(6)A reader YTHDC1 to enhance an oncogenic RNA splicing of tumor suppressor RBM4显示文摘Aberrant RNA splicing produces alternative isoforms of genes to facilitate tumor progression,yet how this process is regulated by oncogenic signal remains largely unknown.Here,we unveil that non-canonical activation of nuclear AURKA promotes an oncogenic RNA splicing of tumor suppressor RBM4 directed by m^(6)A reader YTHDC1 in lung cancer.Nuclear translocation of AURKA is a prerequisite for RNA aberrant splicing,specifically triggering RBM4 splicing from the full isoform(RBM4-FL)to the short isoform(RBM4-S)in a kinase-independent manner. | SiSi Li YangFan Qi JiaChuan Yu YuChao Hao Bin He MengJuan Zhang ZhenWei Dai TongHui Jiang SuYi Li Fang Huang Ning Chen Jing Wang MengYing Yang DaPeng Liang Fan An JinYao Zhao WenJun Fan YuJia Pan ZiQian Deng YuanYuan Luo Tao Guo Fei Peng ZhiJie Hou ChunLi Wang FeiMeng Zheng LingZhi Xu Jie Xu QingPing Wen BiLian Jin Yang Wang Quentin Liu | 2022 | Signal Transduction and Targeted Therapy2022,7,5: | 4 |
| 2 | Psychometric properties of the Chinese version of the Infertility Self-Efficacy Scale显示文摘Objective:To translate the English version of Infertility Self-Efficacy Scale into Chinese and to validate the psychometric properties of the Chinese version of the Infertility Self-Efficacy Scale(CISE).Method(s):Participants were recruited from the Gynecology Department of two city hospitals.Five main processes were involved in the formation of CISE[1]:scale translation based on expert consultation[2];pre-test questionnaire development with infertile women's feedback(N=20)[3];factor structure assessed by exploratory and confirmatory factor analysis(N=177)[4];assessment of reliability by internal consistency(N=177)and test-retest reliability(N=21);and[5]assessment of convergent validity with Self-rating Anxiety Scale,Self-rating Depression Scale,and Simplified Coping Style Questionnaire(N=177).Results:This study established a 16-item CISE.Factor analyses confirmed a onecomponent solution,which explained 54.59% of total variances and showed an acceptable model fit.Cronbach's a and test-retest correlation coefficients for the scale were 0.94 and 0.84,respectively.The CISE score was significantly correlated with anxiety(r=0.47),depression(r=0.60),positive coping style(r=0.37),and certain negative coping style items.Conclusion:This 16-item CISE is a reliable and valid measure to evaluate perceived selfefficacy among a sample of Chinese women who underwent infertility treatment. | Bing Fu Pingping Yan Hang Yin Shujuan Zhu Qing Liu Yulan Liu Chanyuan Dai Guanxiu Tang Chunli Yan Jun Lei | 2016 | International Journal of Nursing Sciences2016,3,3: | 2 |
| 3 | Mechanism for the Nanometer Scale Modification on HOPG Surface by Scanning Tunneling Microscope显示文摘A technique applying voltage across the tunnel junction for wnting permanent features on graphite with lines about 10nm wiidth using our home-built scanning tunneling microscope has been presented.Multiple-tip effects while modifying the surface are often met.The phenomciifi are explained in terms of the strong electric field existing at the junction between the tip an<7 the surface.In addition,the shape of the structure indented by the tip is in agreement with that of the tip. | WANG Zhonghuai DAI Changchun ZHANG Pingchen HUANG Guizhen LI Renli GUO Yi BAI Chunli | 1993 | Chinese Physics Letters1993,10,9: | 2 |
| 4 | A new centimeterdiameter Cu-based bulk metallic glass显示文摘 | Dai Chunli Guo Hua Shen Yong | 2006 | Scr Mater2006,54,: | 1 |
| 5 | Establishment of customized mouse stem cell lines by sequential nuclear transfer显示文摘治疗学的克隆,胚胎的干细胞(转换字符) 由此从原子转移(NT ) 被导出胚胎,可以在再生药的新时代起一个主要作用。Inthis 学习我们建立了四十原子转移 -- 从不同施主房间类型或段落的 NTembryos 被导出的转换字符(NT 转换字符) 线。我们发现 NT 转换字符能够形成胚胎植物或动物身体。另外, NT 转换字符表示了 pluripotency 干细胞标记试管内并且能区分进胚胎的纸巾体内。从施主房间能形成完整的术语的早经过 R1 的 NT 胚胎开发了小狗,而那些为为实时出生是必要的 reprogramming 从迟了的经过 R1 ES 施主房间失去了潜力。我们随后建立了近来从 NT 胚囊被开发的 sequentialNT-R1-ESC 线经过 R1 转换字符施主。然而,当在他们的早段落用作原子转移施主时,这些 NT-R1-ESC 排队,没能导致实时小狗。这显示用顺序的 NT 转换字符的治疗学的克隆过程不能救居住在以前的施主代的发展缺乏。 | Chunli Zhao Ruqiang Yao Jie Hao Chenhui Ding Yong Fan Xiangpeng Dai Wei Li Tang Hai Zichuan Liu Yang Yu Yingying Wang Xiaojun Hou Weizhi Ji Qi Zhou Alice Jouneau Fanyi Zeng Liu Wang | 2007 | Cell Research2007,17,1: | 1 |
| 6 | Improved Constraints on Seismic Source Parameters of the 2011 Tohoku Earthquake from GRACE Grav- ity and Gravity Gradient Changes显示文摘 | Dai Chunli Shum C K Wang Rongjiang | 2014 | Geophysical Research Letters2014,41,6: | 1 |
| 7 | Investigation of stronger diurnal ERP signals in summer derived from the VLBI CONT08 campaign显示文摘A series of very successful Continuous Very Long Baseline Interferometry Campaigns(CONT) have been carried out at irregular intervals since 1994.One of the goals is to support high-resolution earth rotation studies.The most recent CONT08 campaign was conducted with a network of 11 observatories at an increased recording rate of 512 Mbit per second over a fortnightly time span,from which stronger diurnal variations of the Earth Rotation Parameters(ERP) have been detected.We compared the high-frequency ERP from VLBI and GPS observations during CONT02,CONT05 and CONT08 with the atmospheric angular momentum functions derived from the National Centers for Environmental Prediction/National Center for Atmospheric(NCEP/NCAR) during these periods.We attribute the detected diurnal discrepancies between the theoretical models and the CONT08 observations to atmospheric excitations. | SUN Jing DAI ChunLi JIAN NianChuan ZHOU YongHong WANG GuangLi PING JinSong | 2010 | Chinese Science Bulletin2010,55,29: | 1 |
| 8 | A new centimeter-diameter Cu-based bulk metallic glass 显示文摘 | DAI CHUNLI GUO HUA SHEN YONG | 2006 | Scripta Materialia2006,54,7: | 1 |
| 9 | A new centimeter-diameter Cu- based bulk metallic glass显示文摘 | Dai Chunli Guo hua | 2006 | Scripta Mater2006,54,: | 1 |
| 10 | Comparative pluripotency analysis of mouse embryonic stem cells derived from wild-type and infertile hermaphrodite somatic cell nuclear transfer blastocysts显示文摘Therapeutic cloning, whereby embryonic stem cells (ESCs) are derived from patient-specific cloned blastocysts via somatic cell nuclear transfer (SCNT), holds great promise for treating many human diseases using regenerative medicine. Teratoma formation and germline transmission have been used to confirm the pluripotency of mouse stem cells, but human embryonic stem cells (hESCs) have not been proven to be fully pluripotent owing to the ethical impossibility of testing for germ line transmission, which would be the strongest evidence for full pluripotency. Therefore, formation of differentiated cells from the three somatic germ layers within a teratoma is taken as the best indicator of pluripotency in hESC lines. The possibility that these lines lack full multi-or pluripotency has not yet been evaluated. In this study, we established 16 mouse ESC lines, including 3 genetically defective nuclear transfer- ESC (ntESC) lines derived from SCNT blastocysts of infertile hermaphrodite F1 mice and 13 ntESC lines derived from SCNT blastocysts of normal F1 mice. We found that the defective ntESCs expressed all in vitro markers of pluripotency and could form teratomas that included derivatives from all three germ layers, but could not be transmitted via the germ line, in contrast with normal ntESCs. Our results indicate that teratoma formation assays with hESCs might be an insufficient standard to assess full pluripotency, although they do define multipotency to some degree. More rigorous standards are required to assess the safety of hESCs for therapeutic cloning. | FAN Yong TONG Man ZHAO ChunLi DING ChenHui HAO Jie LV Zhuo DAI XiangPeng HAI Tang LI XueMei YAO RuQiang YU Yang LI ZanDong WANG Liu ALICE Jouneau ZHOU Qi | 2008 | Chinese Science Bulletin2008,53,23: | 0 |
| 11 | Preparation of P2O5-SiO_(2) hollow microspheres in the presence of phosphoric acid显示文摘Silica hollow microspheres containing phos-phorous have been prepared by a sol-gel/emulsion method which uses tetraethoxysilane(TEOS)as the precursor for the SiO_(2) and phosphoric acid(H3PO4)as the precursor for P2O5.The hollow structure forms an emulsion system which is composed of an oil phase(kerosene,sorbitan monooleate(Span 80))and an aqueous phase(a viscous sol solution of ethanol,TEOS and H3PO4).Some of the phosphorous remains in thefinal silica shell structure even after calcination at 650°C.The hollow structure of the P2O5-SiO_(2)(silicophosphate)was characterized by X-ray diffraction(XRD),polarized optical microscopy(POM),scanning electron microscopy(SEM),nitrogen adsorption measurement and Fourier transform infrared spectroscopy(FTIR). | Wenjiang LI Fei XIE Dongxu HUA Chunli ZHANG Chen DAI Zhenyun YU Meizhou QI Shaojun YU | 2011 | Frontiers of Chemical Science and Engineering2011,5,3: | 0 |