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| 1 | Endoscopic management of biliary complications after orthotopic liver transplantation显示文摘 | Deepak V. Gopal MD FRCP(C) Patrick R. Pfau MD Michael R. Lucey MD FRCP(I) | 2003 | Current Treatment Options in Gastroenterology2003,,6: | 2 |
| 2 | Subramaniam Ramaswamy Gastric antisecretory and antiulcer activityof oxytocin in rats and guinea pigs显示文摘 | Mohammed Asad Deepak Gopal Shewade Kailasam Koumaravelou | | 0,,: | 1 |
| 3 | Outcomes of Sphincter of Oddi Manometry When Performed in Low Volumes显示文摘 | John P. Rice Bret J. Spier Deepak V. Gopal Anurag Soni Mark Reichelderfer Patrick R. Pfau Tony C. K. Tham | 2011 | Diagnostic and Therapeutic Endoscopy2011,,: | 1 |
| 4 | The role and clinical value of EUS in a multimodality esophageal carcinoma staging program with CT and positron emission tomography显示文摘 | Patrick R. Pfau Scott B. Perlman Peter Stanko Terrence J. Frick Deepak V. Gopal Adnan Said Zhengjun Zhang Tracey Weigel | 2007 | Gastrointestinal Endoscopy2007,,: | 1 |
| 5 | Placement of Gastrostomy Tubes in Patients with Ventriculoperitoneal Shunts Does Not Result in Increased Incidence of Shunt Infection or Decreased Survival显示文摘 | Brent E. Roeder Adnan Said Mark Reichelderfer Deepak V. Gopal | 2007 | Digestive Diseases and Sciences2007,,2: | 1 |
| 6 | Risk Factors for Dysplasia in Patients with Barrett’s Esophagus (BE): Results from a Multicenter Consortium显示文摘 | Deepak V. Gopal David A. Lieberman Nathan Magaret M. Brian Fennerty Richard E. Sampliner Harinder S. Garewal Gary W. Falk Douglas O. Faigel | 2003 | Digestive Diseases and Sciences2003,,8: | 1 |
| 7 | Prospective Blinded Comparison of Polyp Size on Computed Tomography Colonography and Endoscopic Colonoscopy显示文摘 | Courtney Barancin Perry J. Pickhardt David H. Kim Bret Spier Mary Lindstrom Mark Reichelderfer Deepak Gopal Patrick Pfau | 2011 | Clinical Gastroenterology and Hepatology2011,,5: | 1 |
| 8 | Inter and intra-ethnic differences in the distribution of the molecular variants of TPMT, UGT1A1 and MDR1 genes in the South Indian population显示文摘 | Gurusamy Umamaheswaran Dhakchinamoorthi Krishna Kumar Dhandapani Kayathiri Subramanian Rajan Deepak Gopal Shewade Steven Aibor Dkhar Sajjanavar Manjunath Prayaga Ushakiran Gangadharan Reneega Kukreti Ritushree Chandrasekaran Adithan | 2012 | Molecular Biology Reports2012,,5: | 1 |
| 9 | Survey of inflammatory bowel diseases in India显示文摘 | Govind K. Makharia Balakrishnan S. Ramakrishna Philip Abraham Gourdas Choudhuri Sri Prakash Misra Vineet Ahuja Shobna J. Bhatia Deepak K. Bhasin Sunil Dadhich Gopal K. Dhali Devendra C. Desai Uday C. Ghoshal B. D. Goswami Sanjeev K. Issar Ajay K. Jain Ven | 2012 | Indian Journal of Gastroenterology2012,,6: | 1 |
| 10 | Endoscopic ultrasound in the evaluation of pancreatic neoplasms-solid and cystic: A review显示文摘Pancreatic neoplasms have a wide range of pathology, from pancreatic adenocarcinoma to cystic mucinous neoplasms. Endoscopic ultrasound(EUS) with or without fine needle aspiration(FNA) is a helpful diagnostic tool in the work-up of pancreatic neoplasms. Its utility in pancreatic malignancy is well known. Over the last two decades EUS-FNA has become a procedure of choice for diagnosis of pancreatic adenocarcinoma. EUS-FNA is highly sensitive and specific for solid lesions, with sensitivities as high as 80%-95% for pancreatic masses and specificity as high as 75%-100%. Multiple aspects of the procedure have been studied to optimize the rate of diagnosis with EUS-FNA including cytopathologist involvement, needle size, suctioning and experience of endoscopist. Onsite pathology is one of the most important elements in increasing diagnostic yield rate in EUS-FNA. EUS-FNA is valuable in diagnosing rare and atypical pancreatic neoplasms including neuroendocrine, lymphoma and metastatic disease. As more and more patients undergo cross sectional imaging, cystic lesions of the pancreas are becoming a more common occurrence and EUS-FNA of these lesions can be helpful for differentiation. This review covers the technical aspects of optimizing pancreatic neoplasm diagnosis rate, highlight rare pancreatic neoplasms and role of EUS-FNA, and also outline the important factors in diagnosis of cystic lesions by EUS-FNA. | Eric M Nelsen Darya Buehler Anurag V Soni Deepak V Gopal | 2015 | World Journal of Gastrointestinal Endoscopy2015,7,4: | 1 |
| 11 | The role and clinical value of EUS in a multimodality esophageal carcinoma staging program with CT and positron emission tomography显示文摘 | Patrick R. Pfau Scott B. Perlman Peter Stanko Terrence J. Frick Deepak V. Gopal Adnan Said Zhengjun Zhang Tracey Weigel | 2007 | Gastrointestinal Endoscopy2007,,3: | 1 |
| 12 | Endoscopic management of biliary strictures post-liver transplantation显示文摘Biliary complications play a significant role in morbidity of liver transplant recipients. Biliary strictures occur between 10%-25% of patients with a higher incidence in living donor recipients compared to deceased donors. Strictures can be classified as either anastomotic or non-anastomotic and may be related to ischemic events. Endoscopic management of biliary strictures in the posttransplant setting has become the preferred initial approach due to adequate rates of resolution of anastomotic and non-anastomotic strictures(NAS).However, several factors may increase complexity of the endoscopic approach including surgical anatomy, location, number, and severity of bile duct strictures.Many endoscopic tools are available, however, the approach to management of anastomotic and NAS has not been standardized. Multi-disciplinary techniques may be necessary to achieve optimal outcomes in select patients. We will review the risk factors associated with the development of bile duct strictures in the posttransplant setting along with the efficacy and complications of current endoscopic approaches available for the management of bile duct strictures. | Ahmed Akhter Patrick Pfau Mark Benson Anurag Soni Deepak Gopal | 2019 | World Journal of Meta-Analysis2019,7,4: | 0 |
| 13 | 阿片样物质介导多潘立酮和西沙必利对小鼠的镇痛作用(英文) | Isabella TOPNO Mohammed ASAD Deepak Gopal SHEWADE Chanolean SHASHINDRAN Subramanyan RAMASWAMY | 2002 | Acta Pharmacologica Sinica2002,23,1: | 0 |
| 14 | An inherent acceleratory effect of insulin on small intestinal transit and its pharmacological characterization in normal mice显示文摘瞄准:在小肠的运输上学习胰岛素的固有的效果并且在正常 mice.METHODS 探索各种各样的系统 / 机制的参与:在 2 microU/kg, 2 mU/kg, 2 U/kg 或车辆的剂量的胰岛素皮下地予四组一夜的 fasted 正常男性老鼠被以。血葡萄糖(BG ) 层次被测量在胰岛素管理前的 2 min 和在为小肠的运输的测量牺牲动物前的 2 min (坐) 。炭饭被管理(0.3 mL ) intragastrically,在胰岛素管理和动物以后的 20 min 在 20 min 以后被牺牲并且坐被决定。为涉及导致胰岛素的效果在上的各种各样的机制的探索坐,能生产重要加速的胰岛素的剂量没有改变 BG 层次,坐被决定。下列药,颠茄碱(1 mg/kg ) , clonidine (0.1 mg/kg ) , ondansetron (1 mg/kg ) , naloxone (5 mg/kg ) , verapamil (8 mg/kg ) 和 glibenclamide (10 mg/kg ) ,静脉内地被管理在胰岛素(2 microU/kg ) 的管理以前的 10 min。结果:胰岛素( 2 microU/kg 和 2 mU/kg )的更低的剂量生产了重要加速没有阴沉的血葡萄糖层次,从52.0%~70.7%和73.5%坐( P <
0.01 ),当胰岛素( 2 U/kg )的最高的剂量在血生产了秋天时,是的葡萄糖层次也与重要加速联系了坐( P <
0.01 )。在胰岛素(2 microU/kg ) 的预告的处理与颠茄碱组织以后,胰岛素能颠倒颠茄碱生产的 50% 抑制。在 clonidine-pretreated 组,胰岛素管理能仅仅颠倒 clonidine 生产的 37% 抑制和抑制坐与车辆 + 相比是重要的对待胰岛素的组,即从 74.7% ~ 27.7%(P <
0.01 ) 。在 ondansetron-pretreated 组,胰岛素管理能生产仅仅温和的加速坐(23.5%) 。在 naloxone-pretreated 组,胰岛素管理能显著地颠倒抑制坐当与 naloxone 相比本身组织时,由 naloxone 生产了,即从 32.3% ~ 53.9%(P <
0.01 ) 。在 verapamil-pretreated 组,胰岛素管理能仅仅部分颠倒抑制(65%) 。在 glibenclamide-pretreated 组,胰岛素管理生产了进一步的加速坐(12.2%) 。结论:胰岛素内在地拥有 acceleratory 效果在上坐在正常老鼠。肾上腺素能、胆碱能的系统能起一个重要作用。钙隧道和 opioidergic 系统能起一个支持的作用;另外,内长的胰岛素版本罐头的改进扩充外长地管理的胰岛素的效果在上坐。 | Murali Krishna Reddy Peddyreddy Steven Aibor Dkhar Subramanian Ramaswamy Amrithraj Theophilus Naveen Deepak Gopal Shewade | 2006 | World Journal of Gastroenterology2006,12,16: | 0 |
| 15 | Outcomes of colon self-expandable metal stents for malignant vs benign indications at a tertiary care center and review of literature显示文摘BACKGROUND Endoscopic placement of a self-expandable metal stent(SEMS)is a minimally invasive treatment for use in malignant and benign colonic obstruction.However,their widespread use is still limited with a nationwide analysis showing only 5.4%of patients with colon obstruction undergoing stent placement.This underutilization could be due to perceived increase risk of complications with stent placement.AIM To review long-and short-term clinical success of SEMS use for colonic obstruction at our center.METHODS We retrospectively reviewed all the patients who underwent colonic SEMS placement over aeighteen year period (August 2004 through August 2022) at our academic center. Demographicsincluding age, gender, indication (malignant and benign), technical success, clinical success,complications (perforation, stent migration), mortality, and outcomes were recorded.RESULTSSixty three patients underwent colon SEMS over an 18-year period. Fifty-five cases were formalignant indications, 8 were for benign conditions. The benign strictures included diverticulardisease stricturing (n = 4), fistula closure (n = 2), extrinsic fibroid compression (n = 1), and ischemicstricture (n = 1). Forty-three of the malignant cases were due to intrinsic obstruction from primaryor recurrent colon cancer;12 were from extrinsic compression. Fifty-four strictures occurred on theleft side, 3 occurred on the right and the rest in transverse colon. The total malignant case (n = 55)procedural success rate was 95% vs 100% for benign cases (P = 1.0, NS). Overall complication ratewas significantly higher for benign group: Four complications were observed in the malignantgroup (stent migration, restenosis) vs 2 of 8 (25%) for benign obstruction (1-perforation, 1-stentmigration) (P = 0.02). When stratifying complications of perforation and stent migration there wasno significant difference between the two groups (P = 0.14, NS).CONCLUSIONColon SEMS remains a worthwhile option for colonic obstruction related to malignancy and has ahigh procedural and clinical success rate. Benign indications for SEMS placement appear to havesimilar success to malignant. While there appears to be a higher overall complication rate inbenign cases, our study is limited by sample size. When evaluating for perforation alone theredoes not appear to be any significant difference between the two groups. SEMS placement may bea practical option for indications other that malignant obstruction. Interventional endoscopistsshould be aware and discuss the risk for complications in setting of benign conditions. Indicationsin these cases should be discussed in a multi-disciplinary fashion with colorectal surgery. | Saqib Walayat Andrew J Johannes Mark Benson Eric Nelsen Ahmed Akhter Gregory Kennedy Anurag Soni Mark Reichelderfer Patrick Pfau Deepak Gopal | 2023 | World Journal of Gastrointestinal Endoscopy2023,15,4: | 0 |
| 16 | 脑室注射催产素对大鼠胃和十二指肠溃疡的作用显示文摘INTRODUCTION Central neurons that synthesize oxytocin are locatedin the supraoptic(SON) and paraventricular nuclei(PVN) of the hypothalamus. Magnocellular neurons inboth nuclei project to the posterior pituitary gland, | Mohammed AS AD, Deepak Gopal SHEWADE, Kallasam KOUMARAVELOU, Benny K ABRAHAM, Sadashivam VASU, Subramanian RAMASWAMY (Department of Pharmacology, Jawaharlal Institute of Post-graduate Medical Education and Research, Pondicherry 605 006, India) | 2001 | Acta Pharmacologica Sinica2001,22,6: | 0 |