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| 1 | Mitochondrial uncoupler BAM15 inhibits artery constriction and potently activates AMPK in vascular smooth muscle cells显示文摘Our previous studies found that mitochondrial uncouplers CCCP and niclosamide inhibited artery constriction and the mechanism involved AMPK activation in vascular smooth muscle cells. BAM15 is a novel type of mitochondrial uncoupler. The aim of the present study is to identify the vasoactivity of BAM15 and characterize the BAM15-induced AMPK activation in vascular smooth muscle cells(A10 cells). BAM15 relaxed phenylephrine(PE)-induced constricted rat mesenteric arteries with intact and denuded endothelium. Pretreatment with BAM15 inhibited PEinduced constriction of rat mesenteric arteries with intact and denuded endothelium. BAM15, CCCP,and niclosamide had the comparable IC50 value of vasorelaxation in PE-induced constriction of rat mesenteric arteries. BAM15 was less cytotoxic in A10 cells compared with CCCP and niclosamide.BAM15 depolarized mitochondrial membrane potential, induced mitochondrial fission, increased mitochondrial ROS production, and increased mitochondrial oxygen consumption rate in A10 cells.BAM15 potently activated AMPK in A10 cells and the efficacy of BAM15 was stronger than that of CCCP, niclosamide, and AMPK positive activators metformin and AICAR. In conclusion, BAM15 activates AMPK in vascular smooth muscle cells with higher potency than that of CCCP, niclosamide and the known AMPK activators metformin and AICAR. The present work indicates that BAM15 is a potent AMPK activator. | Yu Tai Lanjun Li Xuan Peng Junxue Zhu Xihai Mao Nan Qin Minghui Ma Rong Huo Yunlong Bai Deli Dong | 2018 | Acta Pharmaceutica Sinica B2018,8,6: | 5 |
| 2 | Seed dormancy and germination characteristics of two Rheum species in the Himalaya-Hengduan Mountains显示文摘Seed dormancy and germination characteristics are important factors determining plant reproductive success, and may be expected to have a major influence on plant distribution. In this study, we aimed to explore the characteristics of seed dormancy and germination in two endemic Rheum species(Rheum nobile and Rheum alexandrae) in the Himalaya-Hengduan Mountains. To determine the type of dormancy,fresh seeds of the two species(one population each) were incubated in light at 25/15 and 15/5℃, and then dry after-ripening(DAR) seeds were incubated on water agar substrate with or without GA_3. To determine the effect of temperature and light on germination, DAR seeds of the two species(two populations each) were incubated both in the light and in the dark at several temperatures, including constant and alternating temperatures. Base temperature(T_b) and thermal times for 50% germination(θ_(50)) were calculated. DAR released physiological dormancy(PD), increasing final germination at 15/5℃ and widening the range of germination temperatures from higher to lower, indicative of type 2 non-deep PD for the two Rheum species. Light had no significant effect on germination of seeds from the two species(two populations each). Seeds of the two species germinated significantly better(>80%) at medium temperatures(10-25℃) than at extreme low(5℃) or high(35℃) temperatures. Alternating temperatures(25/15 and 15/5℃) did not significantly increase the final germination of the two species either in the light and in the dark, but it promoted seed germination more quickly than corresponding constant temperatures in the light in both Rh. alexandrae populations, especially at 15/5℃. Germination in response to temperature was well described by the thermal-time model at suboptimal temperatures. The estimated Tbvalues were 1 and 0.9℃, respectively, in two Rh. nobile populations; 4 and 4.1℃,respectively, in two Rh. alexandrae populations; θ_(50)(thermal time) were 100 and 125℃d, respectively in two Rh. nobile populations; 76.92 and 83.33℃d, respectively in two Rh. alexandrae populations. The dormancy type, and germination responses to temperature and light condition does not explain why the two Rheum species are distributed in contrasting habitats. However, these findings reflect an advantageous germination strategy of these two Rheum species to adapt to the same alpine environments. | Deli Peng Zhe Chen Xiaojian Hu Zhimin Li Bo Song Hang Sun | 2017 | Plant Diversity2017,39,4: | 4 |
| 3 | Function of male and hermaphroditic flowers and size-dependent gender diphasy of Lloydia oxycarpa (Liliaceae) from Hengduan Mountains显示文摘Although hermaphroditism is common in flowering plants, unisexual flowers occur in many plant taxa,forming various sexual systems. However, the sexual system of some plants is difficult to determine morphologically, given that their sex expression may be influenced by both genetic and environmental factors. Specifically, androdioecy(the coexistence of both male and hermaphroditic individuals in the same population) has often been confused with the gender diphasy, a gender strategy in which plants change their sex expression between seasons. We studied the reproductive function of male and hermaphroditic flowers of Lloydia oxycarpa(Liliaceae), in order to investigate its sexual system and determine whether it is a gender-diphasic species. We found that although male flowers occur in a considerable number of plants, relative to hermaphrodites, they did not exhibit any significant reproductive advantage in terms of flower size, pollen quantity, attractiveness to visitors or siring success. In addition, this plant has spontaneous self-pollination and showed no inbreeding depression. These results render the maintenance of male individuals almost impossible. Furthermore, a considerable number of individuals changed their sex in successive years. The sex expression was found to be related to bulb size and dry weight, with larger individuals producing hermaphroditic flowers and smaller individuals producing male flowers. These results suggest that L. oxycarpa is not an androdioecious plant but represents a rare case of size-dependent gender diphasy. | Yang Niu Qiangbang Gong Deli Peng Hang Sun Zhimin Li | 2017 | Plant Diversity2017,39,4: | 3 |
| 4 | 2020 Roadmap on two-dimensional nanomaterials for environmental catalysis显示文摘Environmental catalysis has drawn a great deal ofattention due to its clean ways to produce useful chemicals or carry out some chemical processes.Photocatalysis and electrocatalysis play important roles in these fields.They can decompose and remove organic pollutants from the aqueous environment,and prepare some fine chemicals.Moreover,they also can carry out some important reactions,such as 02 reduction reaction(ORR),O2 evolution reaction(OER),H2 evolution reaction(HER),CO2 reduction reaction(C02 RR),and N2 fixation(NRR).For catalytic reactions,it is the key to develop high-performance catalysts to meet the demand fortargeted reactions.In recentyears,two-dimensional(2 D) materials have attracted great interest in environmental catalysis due to their unique layered structures,which offer us to make use of their electronic and structural characteristics.Great progress has been made so far,including graphene,black phosphorus,oxides,layered double hydroxides(LDHs),chalcogenides,bismuth-based layered compounds,MXenes,metal organic frameworks(MOFs),covalent organic frameworks(COFs),and others.This content drives us to invite many famous groups in these fields to write the roadmap on two-dimensional nanomaterials for environmental catalysis.We hope that this roadmap can give the useful guidance to researchers in future researches,and provide the research directions. | Yulu Yang Mingguang Wu Xingwang Zhu Hui Xu Si Ma Yongfeng Zhi Hong Xia Xiaoming Liu Jun Pan Jie-Yinn Tang Siang-Piao Chai Leonardo Palmisano Francesco Parrino Junli Liu Jianzhong Ma Ze-Lin Wang Ling Tan Yu-Fei Zhao Yu-Fei Song Pardeep Singh Pankaj Raizada Deli Jiang Di Li R.A.Geioushy Jizhen Ma Jintao Zhang Song Hu Rongjuan Feng Gang Liu Minghua Liu Zhenhua Li Mingfei Shao Neng Li Jiahe Peng Wee-Jun Ong Nikolay Kornienko Zhenyu Xing Xiujun Fan Jianmin Ma | 2019 | Chinese Chemical Letters2019,30,12: | 2 |
| 5 | Formation and control of the surface defect in hypo-peritectic steel during continuous casting:A review显示文摘Hypo-peritectic steels are widely used in various industrial fields because of their high strength,high toughness,high processability,high weldability,and low material cost.However,surface defects are liable to occur during continuous casting,which includes depression,longitudinal cracks,deep oscillation marks,and severe level fluctuation with slag entrapment.The high-efficiency production of hypo-peritectic steels by continuous casting is still a great challenge due to the limited understanding of the mechanism of peritectic solidification.This work reviews the definition and classification of hypo-peritectic steels and introduces the formation tendency of common surface defects related to peritectic solidification.New achievements in the mechanism of peritectic reaction and transformation have been listed.Finally,countermeasures to avoiding surface defects of hypo-peritectic steels duiring continuous casting are summarized.Enlightening certain points in the continuous casting of hypo-peritectic steels and the development of new techniques to overcome the present problems will be a great aid to researchers. | Quanhui Li Peng Lan Haijie Wang Hongzhou Ai Deli Chen Haida Wang | 2023 | International Journal of Minerals,Metallurgy and Materials2023,30,12: | 0 |
| 6 | Submarine groundwater discharge around Taiwan显示文摘A preliminary study shows that the submarine groundwater discharge(SGD) exists around Taiwan even though groundwater overdrawing on the island is serious. Fifteen of the 20 sites studied for major anions and cations recorded a clear SGD signal with freshwater outflow. A total of 278 salinity and major ion measurements were made. Sixteen nearly freshwater SGD(salinity≤1.0) samples were obtained, providing strong and direct evidence for the existence of fresh meteoric groundwater entering the ocean from Taiwan. The total SGD flux is estimated to be 1.07×1010 t/a which is about 14% of the annual river output. The freshwater component of the SGD is3.85×109 t which is about 5.2% of the annual river discharge in Taiwan. The collected SGD has a composition similar to seawater with an addition of Ca, CO_3 and HCO_3 due to dissolution of calcareous rocks. Some samples with high Cl/(Na+K) may indicate pollution. | CHEN Chen-Tung Arthur ZHANG Jing PENG Tsung-Ren KANDASAMY Selvaraj WANG Deli LIN Yi-Jie | 2018 | Acta Oceanologica Sinica2018,37,6: | 0 |
| 7 | 3D numerical simulation in acoustic-elastic coupled media with staggered-grid finite-difference method显示文摘Acoustic-elastic coupled media is often encountered in most marine explorations, and accurate simulation of acoustic-elastic coupled media is of great significance. At present, the study of acoustic-elastic coupled media still assumes that the solid of the acoustic-elastic coupled media is isotropic, but this assumption is not in accordance with the actual situation. In this paper, we derive the solid media of acoustic-elastic coupled media from isotropic media to anisotropic media, and propose an acoustic-elastic coupled medium based ontransverse isotropic media with vertical symmetric axes(VTI) to improve the accuracy of forward modeling. Based on the relationship between the Thomsen parameter and the coefficient matrix of the anisotropic elastic wave equation, we transform the Thomson parameter into a velocity model with anisotropic properties. We use a staggered grid finite difference method to simulate the propagation of a wavefield in a three-dimensional acoustic-elastic coupled media. We obtain the snapshots of the wave field when the solid of the acoustic-elastic coupled media is an isotropic medium and a VTI media. When the solid of the acoustic-elastic coupled media is considered VTI media, we can observe the qP wave and qS wave that cannot be observed in the isotropic medium from the wave field snapshot. We can also find that the seismic records obtained by the method we use are more realistic. The algorithm proposed in this paper is of great significance for high-precision ocean numerical simulation. | PENG Changhua WANG Deli ZHOU Jinju | 2019 | Global Geology2019,22,2: | 0 |
| 8 | Investigation on the Formation Mechanism of Double-Layer Vertically Aligned Carbon Nanotube Arrays via Single-Step Chemical Vapour Deposition显示文摘The mechanism for the formation of double-layer vertically aligned carbon nanotube arrays(VACNTs) through single-step CVD growth is investigated. The evolution of the structures and defect concentration of the VACNTs are tracked by scanning electron microscopy(SEM) and Raman spectroscopy. During the growth, the catalyst particles are stayed constantly on the substrate. The precipitation of the second CNT layer happens at around 30 min as proved by SEM.During the growth of the first layer, catalyst nanoparticles are deactivated with the accumulation of amorphous carbon coatings on their surfaces, which leads to the termination of the growth of the first layer CNTs. Then, the catalyst particles are reactivated by the hydrogen in the gas flow, leading to the precipitation of the second CNT layer. The growth of the second CNT layer lifts the amorphous carbon coatings on catalyst particles and substrates. The release of mechanical energy by CNTs provides big enough energy to lift up amorphous carbon flakes on catalyst particles and substrates which finally stay at the interfaces of the two layers simulated by finite element analysis. This study sheds light on the termination mechanism of CNTs during CVD process. | Shoumo Zhang Deli Peng Huanhuan Xie Quanshui Zheng Yingying Zhang | 2017 | Nano-Micro Letters2017,9,1: | 0 |
| 9 | 100 km wear-free sliding achieved by microscale superlubric graphite/DLC heterojunctions under ambient conditions显示文摘Wear-free sliding between two contacted solid surfaces is the ultimate goal in the effort to extend the lifetime of mechanical devices,especially when it comes to inventing new types of micro-ele ctromechanical systems where wear is often a major obstacle.Here we report experimental observations of wear-free sliding for a micrometer-sized graphite flake on a diamond-like-carbon(DLC) surface under ambient conditions with speeds up to 2.5 m/s,and over a distance of 100 km.The coefficient of friction(COF) between the microscale graphite flake,a van der Waals(vdW) layered material and DLC,a non-vdW-layered material,is measured to be of the order of 10^(-3),which belongs to the superlubric regime.Such ultra-low COFs are also demonstrated for a microscale graphite flake sliding on six other kinds of non-vdW-layered materials with sub-nanometer roughness.With a synergistic analysis approach,we reve al the underlying mechanism to be the combination of interfacial vdW interaction,atomic-smooth interfaces and the low normal stiffness of the graphite flake.These features guarantee a persistent full contact of the interface with weak interaction,which contributes to the ultra-low COFs.Together with the extremely high in-plane strength of graphene,wear-free sliding is achieve d.Our results broaden the scope of superlubricity and promote its wider application in the future. | Deli Peng Jin Wang Haiyang Jiang Shuji Zhao Zhanghui Wu Kaiwen Tian Ming Ma Quanshui Zheng | 2022 | National Science Review2022,9,1: | 0 |
| 10 | Patterns and drivers of plant sexual systems in the dry-hot valley region of southwestern China显示文摘Sexual systems play important roles in angiosperm evolution and exhibit substantial variations among different floras. Thus, studying their evolution in a whole flora is crucial for understanding the formation and maintenance of plant biodiversity and predicting its responses to environmental change. In this study, we determined the patterns of plant sexual systems and their associations with geographic elements and various life-history traits in dry-hot valley region of southwestern China, an extremely vulnerable ecosystem. Of the 3166 angiosperm species recorded in this area, 74.5% were hermaphroditic,13.5% were monoecious and 12% were dioecious, showing a high incidence of diclinous species. Diclinous species were strongly associated with tropical elements, whereas hermaphroditic species were strongly associated with temperate and cosmopolitan elements. We also found that hermaphroditism was strongly associated with showy floral displays, specialist entomophily, dry fruits and herbaceous plants.Dioecy was strongly associated with inconspicuous, pale-colored flowers, generalist entomophily, fleshy fruits, and woody plants, whereas monoecy was strongly associated with inconspicuous, pale-colored flowers, anemophily, dry fruits, and herbaceous plants. In addition, hermaphroditic species with generalist entomophily tended to flower in the dry season, whereas diclinous species with specialist entomophily tended to flower in the rainy season. However, independent of sexual systems, plants that produce dry fruits tended to flower in the rainy season and set fruits in the dry season, but the opposite pattern was found for fleshy fruit-producing plants. Our results suggest that in the dry-hot valleys, plant sexual systems are associated with geographic elements as well as various life-history traits that are sensitive to environmental change. | Rong Ma Qi Xu Yongqian Gao Deli Peng Hang Sun Bo Song | 2024 | Plant Diversity2024,46,2: | 0 |