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| 1 | In vitro effect of pantoprazole on lower esophageal sphincter tone in rats显示文摘AIM:To investigate the in vitro effects of pantoprazole on rat lower esophageal sphincter(LES)tone.METHODS:Rats weighing 250-300 g,provided by the Yeditepe University Experimental Research Center(Yü-DETAM),were used throughout the study.They were anesthetized before decapitation.LES tissues whose mucosal lining were removed were placed in a stan-dard 30-mL organ bath with a modif ied Krebs solution and continuously aerated with 95% oxygen-5% carbon dioxide gas mixture and kept at room temperature.The tissues were allowed to stabilize for 60 min.Sub-sequently,the contractile response to 10-6 mol/L carba-chol was obtained.Different concentrations of freshly prepared pantoprazole were added directly to the tis-sue bath to generate cumulative concentrations of 5×10-6 mol/L,5×10-5 mol/L,and 1.5×10-4 mol/L.Activi-ties were recorded on an online computer via a 4-channeltransducer data acquisition system using the software BSL PRO v 3.7,which also analyzed the data.RESULTS:Pantoprazole at 5×10-6 mol/L caused a small,but statistically insignif icant,relaxation in the car-bachol-contracted LES(2.23% vs 3.95%).The 5×10-5 mol/L concentration,however,caused a signif icant relax-ation of 10.47% compared with the control.1.5×10-4 mol/L concentration of pantoprazol caused a 19.89% relaxation in the carbachol contracted LES(P<0.001).CONCLUSION:This is the fi rst study to demonstrate that pantoprazole has a relaxing effect in isolated LESs.These results might have signif icant clinical implications for the subset of patients using proton pump inhibitors who do not receive full symptomatic alleviation from gastroesophageal reflux disease. | Mustafa Duman Mahmut zer Enver Rean Yeliz Demirci Ali E Atιcι Tahsin Dalgι Erdal B Bostancι Ece Gen | 2011 | World Journal of Gastroenterology2011，17，46： | 3 |
| 2 | Impacts of urban growth on forest cover in Istanbul ( 1987 - 2007) 显示文摘 | Ahmet Karaburun Ali Demirci I - Shian Suen | 2010 | Environ Monit Assess2010，166，1234： | 1 |
| 3 | A micro–macro combined approach using FEM for modelling of machining of FRP composites: Cutting forces analysis显示文摘 | Ali Mkaddem Ibrahim Demirci Mohamed El Mansori | 2008 | Composites Science and Technology2008，，15： | 1 |
| 4 | A micro–macro combined approach using FEM for modelling of machining of FRP composites: Cutting forces analysis显示文摘 | Ali Mkaddem Ibrahim Demirci Mohamed El Mansori | 2008 | Composites Science and Technology2008，，15： | 1 |
| 5 | Online recovery of nisin during fermentation and its effect on nisin production in biofilm reactor显示文摘 | Thunyarat Pongtharangku Ali Demirci | 2007 | Applied Microbiology and Biotechnology2007，，3： | 1 |
| 6 | Essential oils of green and red Perilla frutescens as potential sources of compounds for mosquito management显示文摘 | Tabanca N Demirci B Ali A | 2015 | Industrial Crops and Products2015，65，： | 1 |
| 7 | Effects of pH profiles on nisin production in biofilm reactor显示文摘 | Thunyarat Pongtharangkul Ali Demirci | 2006 | Applied Microbiology and Biotechnology2006，，6： | 1 |
| 8 | Ⅲ Enhanced Production of D-(-)-lactic acid by mutants of Lactobacillus delbrueckii ATCC9649显示文摘 | Demirci Ali Pometto A L | 1992 | J Ind Microbiol1992，，11： | 1 |
| 9 | Enhanced organically bound chromium yeast production显示文摘 | Ali Demirci Anthony L Pometto Ⅲ | 2000 | Journal of agriculture food chemistry2000，48，： | 1 |
| 10 | Coastline chang- es in Istanbul between 1987 and 2007显示文摘 | Kurt Sumeyra Karaburun Ahmet Demirci Ali | 2010 | Scientific Research and Essays2010，5，19： | 1 |
| 11 | Essential oils of green and red Perilla frutescens as potential sources of compounds for mosquito management显示文摘 | Nurhayat Tabanca Betul Demirci Abbas Ali | 2015 | Industrial Crops and Products2015，，65： | 1 |
| 12 | Factors Affecting Complication Rates of Percutaneous Nephrolithotomy in Children: Results of a Multi-Institutional Retrospective Analysis by the Turkish Pediatric Urology Society显示文摘 | Bülent ?nal Hasan Serkan Dogan Nihat Satar Cenk Y. Bilen Ali Güne? Ender ?zden Ahmet Ozturk Deniz Demirci Okan ?stanbulluo?lu Serhat Gurocak Oktay Nazli Orhan Tanriverdi Aykut Kefi Esat Korgali Mesrur Selcuk Silay Kubilay Inci Volkan ?zol Ramazan Altintas | 2014 | The Journal of Urology2014，，3： | 1 |
| 13 | Essential oils of green and red PeriUafruteseens as potential sourees of compounds for mosquito management 显示文摘 | Tabanca N Demirci B Ali A | 2015 | Industrial Crops and Prod- ucts2015，65，： | 1 |
| 14 | Disinfection of water by flow-through a pulsed uv light steriluzation system显示文摘 | Ali Demirci Kathiravan Krishnamurthy | 2007 | Ultrapre Water2007，，2： | 1 |
| 15 | Production of organically bound selenium yeast by continuous fermentation显示文摘 | Ali Demirci etal | 1999 | Agric Food Chem1999，47，： | 1 |
| 16 | Electrolyzed oxidizing water treatment for decontamination of raw salmon inoculated with Escherichia coli O157:H7 and Listeria monocytogenes Scott A and response surface modeling显示文摘 | Nil P. Ozer Ali Demirci | 2005 | Journal of Food Engineering2005，，3： | 1 |
| 17 | Rates and associates of influenza and pneumococcus vaccination in diabetes mellitus:A nationwide cross-sectional study(TEMD vaccination study)显示文摘BACKGROUND Vaccination against influenza and pneumococcus is effective in reducing morbidity and mortality in patients with diabetes.AIM To investigate the prevalence of influenza and pneumococcal vaccinations and to search for the independent associates of vaccination in Turkish patients with diabetes.METHODS In this cross-sectional,nationwide,multicenter study,adult patients with type 1 diabetes(T1DM)(n=454)and type 2 diabetes(T2DM)(n=4721),who were under follow-up for at least a year in the outpatient clinics,were consecutively enrolled.Sociodemographic,clinical,and laboratory parameters of patients were recorded.Vaccination histories were documented according to the self-statements of the patients.RESULTS Patients with T1DM and T2DM had similar vaccination rates for influenza(23.6%vs 21.2%;P=0.240)and pneumococcus(8%vs 7%;P=0.451)vaccinations.Longer diabetes duration and older age were the common independent associates of having vaccination for both types of diabetes patients.Higher education level,using statin treatment,and having optimal hemoglobin A1c levels were the common independent associates of influenza and pneumococcal vaccination in patients with T2DM.CONCLUSION TEMD Vaccination Study shows that patients with T1DM and T2DM had very low influenza and pneumococcal vaccination rates in Turkey.The lower rates of vaccination in certain populations urges the necessity of nationwide vaccination strategies targeting these populations. | Ibrahim Demirci Cem Haymana Serpil Salman Ilker Tasci Demet Corapcioglu Ali Kirik İlhan Yetkin Mustafa Altay Tevfik Sabuncu Fahri Bayram Ilhan Satman Alper Sonmez 无 | 2021 | World Journal of Diabetes2021，12，12： | 0 |
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