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| 1 | 冠状动脉内影像学临床应用专家共识(第一部分):对冠状动脉介入治疗的指导与优化显示文摘欧洲心血管介入协会(EAPCI)专家组系统总结了血管内超声(IVUS)和光学相干断层成像(OCT)这两种血管内影像学检查临床应用指征的现有证据,提供了关于IVUS和OCT指导经皮冠状动脉介入治疗(PCI)的应用价值,并明确了最可能从腔内影像学指导的介入治疗中获得临床收益的患者或病变类型,同时详细论述了PCI前如何使用IVUS或OCT优化支架尺寸(支架长度和直径)和手术策略的选择。此外,专家推荐对支架失败(支架内再狭窄或支架内血栓形成)的患者应常规进行冠状动脉内影像学检查,并首选OCT。最后,重点论述了IVUS和OCT在指导PCI和评估支架失败两个方面的优势和局限性,并对未来需要深入研究的领域进行了展望。 | Lorenz Raber Gary S Mintz Konstantinos C Koskinas Thomas W Johnson Niels R Holm Yoshinubo Onuma Maria D Radu Michael Joner Bo Yu Haibo Jia Nicolas Meneveau Jose M.de la Torre Hemandez Javier Escaned Jonathan Hill Francesco Prati Antonio Colombo Carlo di Mario Evelyn Regar Davide Capodanno William Wijns Robert A Byme Giulio Guagliumi | 2019 | 中华心血管病杂志2019，47，1： | 17 |
| 2 | New fecal test for non-invasive Helicobacter pylori detection:A diagnostic accuracy study显示文摘AIM To assess the diagnostic accuracy of a new fecal test for detecting Helicobacter pylori(H. pylori), using ^(13)Curea breath test as the reference standard, and explore bacterial antibiotic resistance. METHODS We conducted a prospective two-center diagnostic test accuracy study. We enrolled consecutive people≥ 18 years without previous diagnosis of H. pylori infection, referred for dyspepsia between February and October 2017. At enrollment, all participants underwent 13 C-urea breath test. Participants aged over 50 years were scheduled to undergo upper endoscopy with histology. Participants collected stool samples 1-3 d after enrollment for a new fecal investigation(THD fecal test). The detection of bacterial 23 S rRNA subunit gene indicated H. pylori infection. We also used the index diagnostic test to examine mutations conferring resistance to clarithromycin and levofloxacin. Independent investigators analyzed index test and reference test standard results blinded to the other test findings. We estimated sensitivity, specificity, positive(PPV) and negative(NPV) predictive value, diagnostic accuracy, positive and negative likelihood ratio(LR), together with 95% confidence intervals(CI).RESULTS We enrolled 294 consecutive participants(age: Median 37.0 years, IQR: 29.0-46.0 years; men: 39.8%). Ninetyfive(32.3%) participants had a positive ^(13)C-urea breath test. Twenty-three(7.8%) participants underwent upper endoscopy with histology, with a full concordance between ^(13)C-urea breath test and histology in detecting H. pylori infection. Four(1.4%) out of the 294 participants withdrew from the study after the enrollment visit and did not undergo THD fecal testing. In the 290 participants who completed the study, the THD fecal test sensitivity was 90.2%(CI: 84.2%-96.3%), specificity 98.5%(CI:96.8%-100%), PPV 96.5%(CI: 92.6%-100%), NPV 95.6%(CI: 92.8%-98.4%), accuracy 95.9%(CI: 93.6%-98.2%), positive LR 59.5(CI: 19.3-183.4), negative LR 0.10(CI: 0.05-0.18). Out of 83 infected participants identified with the THD fecal test, 34(41.0%) had bacterial genotypic changes consistent with antibiotic-resistant H. pylori infection. Of these, 27(32.5%) had bacterial strains resistant to clarithromycin, 3(3.6%) to levofloxacin, and 4(4.8%) to both antibiotics. CONCLUSION The THD fecal test has high performance for the non-invasive diagnosis of H. pylori infection while additionally enabling the assessment of bacterial antibiotic resistances. | Andrea Iannone Floriana Giorgio Francesco Russo Giuseppe Riezzo Bruna Girardi Maria Pricci Suetonia C Palmer Michele Barone Mariabeatrice Principi Giovanni FM Strippoli Alfredo Di Leo Enzo Ierardi | 2018 | World Journal of Gastroenterology2018，24，27： | 5 |
| 3 | Retinoic acid receptors and cancer: from molecular mechanisms to therapy显示文摘 | Alessandra di Masi Loris Leboffe Elisabetta De Marinis Francesca Pagano Laura Cicconi Cécile Rochette-Egly Francesco Lo Coco Paolo Ascenzi Clara Nervi | 2014 | Molecular Aspects of Medicine2014，，： | 2 |
| 4 | Importance of the traceability of animals and animal products in epidemiology显示文摘 | Caporale V Giovannini A Francesco C Di | 2001 | Rev sci tech Off lnt Epiz2001，20，2： | 1 |
| 5 | The NIH human microbiome project显示文摘 | NIH HMP Working Group Peterson J Garges S Giovanni M McInnes P Wang L Schloss JA Bonazzi V McEwen JE Wetterstrand KA Deal C Baker CC Di Francesco V Howcroft TK Karp RW Lunsford RD Wellington CR Belachew T Wright M Giblin C David H Mills M Salomon R Mullins C Akolkar B Begg L Davis C Grandison L Humble M Khalsa J Little AR Peavy H Pontzer C Portnoy M Sayre MH Starke-Reed P Zakhari S Read J Watson B Guyer M | 2009 | Genome Res2009，19，12： | 1 |
| 6 | Plasma endothelin-1 levels in patients with systemic sclerosis: influence of pulmonary or systemic arterial hypertension显示文摘 | Ferri C Di Francesco L | 1995 | Ann Rheum Dis1995，54，9： | 1 |
| 7 | Energy conservation in wireless sensor networks: A survey显示文摘 | ANASTASI G MARCO C DI FRANCESCO M | 2009 | Ad Hoc Networks2009，7，3： | 1 |
| 8 | The use of hook plate in type III and V acromio-clavicular Rockwood dislocations: clinical and radiological midterm results and MRI evaluation in 42 patients显示文摘 | Di Francesco A Zoccali C Colafarina O | 2012 | Injury2012，43，2： | 1 |
| 9 | Modulation of fluorouracil by methotrexate,leucovofin and cisplatin(M -FLP)in the treatment of advanced pancreatic cancer显示文摘 | Rodolfo C | 2000 | Am J Oncol2000，23，3： | 1 |
| 10 | Biological control of postharvestdiseases by microbial antagonists : how many mechanisms of action显示文摘 | Di Francesco A Martini C Mari M | 2016 | European Journal of Plant Pathology2016，，： | 1 |
| 11 | Anti-IL2 in-duction in liver transplantation with 93% rejection-free patient and graft survival at 18 months显示文摘 | RAMIREZ CB DORIA C DI FRANCESCO F | 2007 | J Surg Res2007，138，2： | 1 |
| 12 | Synthesis ofγ-aminobutyric acid(GABA)by Lactobacillus plantarum DSM19463:functional grape must beverage and dermatological applica-tions显示文摘 | RAFFAELLA DI C FRANCESCO MAZZACANE CARLO GIUSEPPE R | 2010 | Applied Microbial and Physiology2010，86，： | 1 |
| 13 | The use of hook plate in type III and V acromio-clavicular Rockwood dislocations:Clinical and radiological midterm results and MRI evaluation in 42 patients显示文摘 | Di Francesco A Zoccali C Colafarina O | | 0，，： | 1 |
| 14 | Reversible immobilization of engineered mol/Lecules by Ni-NTA chelators 显示文摘 | Maly J Di Meo C De Francesco M | 2004 | Bioelectrochemistry2004，63，6： | 1 |
| 15 | Comparison of angiographic and clinical outcomes of coronary stenting of chronic total occlusions versus subtotal occlusions 显示文摘 | Moussa I Di Mario C Moses J Reimers B Di Francesco L Blengino S | 1998 | Am J Cadiol1998，81，： | 1 |
| 16 | Clinical and radiologieal midterm results from using the Fixion expandable intramedullary nail in transverse and short oblique fractures of femur and tibia显示文摘 | Zoccali C Di Francesco A Ranalletta A | 2008 | J Orthop Traumatol2008，9，3： | 1 |
| 17 | The use of hook plate in type Ⅲ and Ⅴ acromio-clavicular Rockwood dislocations:clinical and radiological midterm results and MRI evaluation in 42 patients显示文摘 | Di Francesco A Zoccali C Colafarina O | | 0，，02： | 1 |
| 18 | Dihydroxypyri- midine-4-carboxamides as novel potent and selective HIV integrase inhibitors 显示文摘 | Pace P Di Francesco ME Gardelli C | 2007 | J Med Chem2007，50，： | 1 |
| 19 | Involvement of 5lipoxygenase in Alzheimer′s disease: a role for DNA methylation显示文摘 | Di Francesco A Arosio B Gussago C | 2013 | J Alzheimers Dis2013，37，1： | 1 |
| 20 | Systemic admin- istration of ghrelin increases extracellular dopamine in the shell but not the core subdivision of the nucleus accumbens显示文摘 | Quarta D Di Francesco C Melotto S | 2009 | Neurochem Int2009，54，2： | 1 |
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