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| 1 | 源于近端股骨间充质干细胞免疫抑制作用的研究显示文摘目的探讨源于成人近端股骨的间充质干细胞(MSC)是否具有免疫抑制功能,为临床移植物抗宿主病的防治寻找理想的细胞储备库。方法从全髋关节置换术患者的近端股骨中分离并培养MSC,将不同数量的细胞直接或以Transwell法加入混合淋巴细胞反应(MLR)中,检测MSC对外周血淋巴细胞(PBL)增殖水平的影响。以ELISA法及抗体中和法探讨细胞因子TGFβ1在MSC免疫调节中的作用。结果3×103、1×104、3×104、1×105个源于近端股骨的MSC对PBL增殖的抑制率分别为62%±18%、38%±4%、31%±16%、28%±12%,与采自髂骨骨髓穿刺物MSC的抑制作用相比差异无统计学意义(均P>0.05),后者对PBL的增殖抑制率为58%±12%、37%±8%、28%±6%、27%±6%;以0.2μm的微孔膜对MSC与MLR进行分隔,3×104及1×104个MSC对PBL的增殖抑制率为36%±8%和53%±12%;在ELISA实验中,MSC单独培养,MSC与MLR直接接触,或经Transwell共培养的这3种上清中转化生长因子(TGF)β1的表达水平差异无统计学意义,加入浓度递增的TGFβ1抗体不能逆转MSC对PBL增殖的抑制作用。结论源于近端股骨的MSC具有一定的免疫抑制功能,除TGFβ1外其他可溶性因子可能介导这一作用。 | 张翼鷟 Loic Fouillard Alain Chapel Morad Bensidhoum Christelle Mazurier Aish Nasef Sandrine Bouchet Manuel Lopez Dominique Thierry Norbert Cclaucle Gorin 达万明 | 2005 | 中华医学杂志2005,85,39: | 11 |
| 2 | Applicability and variability of liver stiffness measurements according to probe position显示文摘AIM: To investigate the liver stiffness measurement (LSM) applicability and variability with reference to three probe positions according to the region of liver biopsy. METHODS: The applicability for LSM was defined as at least 10 valid measurements with a success rate greater than 60% and an interquartile range/median LSM < 30%. The LSM variability compared the inter-position concordance and the concordance with FibroTest. RESULTS: Four hundred and forty two consecutive patients were included. The applicability of the anterior position (81%) was significantly higher than that of the reference (69%) and lower positions (68%), (both P = 0.0001). There was a signif icant difference (0.5 kPa, 95% CI 0.13-0.89; P < 0.0001) between mean LSM estimated at the reference position (9.3 kPa) vs the anterior position (8.8 kPa). Discordance between positions was associated with thoracic fold (P = 0.008). The discordance rate between the reference position result and FibroTest was higher when the 7.1 kPa cutoff was used to define advanced fibrosis instead of 8.8 kPa (33.6% vs 23.5%, P = 0.03).CONCLUSION: The anterior position of the probe should be the fi rst choice for LSM using Fibroscan, as it has a higher applicability without higher variability compared to the usual liver biopsy position. | Patrick Ingiliz Kim Pav Chhay Mona Munteanu Pascal Lebray Yen Ngo Dominique Roulot Yves Benhamou Dominique Thabut Vlad Ratziu Thierry Poynard | 2009 | World Journal of Gastroenterology2009,15,27: | 5 |
| 3 | 利用IRAS研究锌表面在湿干交替条件下的腐蚀行为显示文摘设计了一套原位红外反射吸收电池 ,可以研究Zn在干湿交替条件下的腐蚀过程和溶液在Zn表面的挥发过程 ,结果表明溶液在Zn表面的挥发主要有三个阶段 .局部Zn表面在 1%NaCl溶液中浸泡 1h后在湿度为 5 0 %的净化空气中干燥 2 3h的周期性湿干交替试验 ,腐蚀产物主要是ZnO ,腐蚀产物的量在初期随着周期 (d)的增大而线性增加 .在 2 3h的干燥过程中 ,Zn的腐蚀速率随着干燥时间的增加而降低 . | 张学元 韩恩厚 Dan Persson Dominique Thierry | 2002 | 中国腐蚀与防护学报2002,22,1: | 3 |
| 4 | The Clinical Efficacy and Pharmacokinetics of Intraperitoneal Ropivacaine for Laparoscopic Cholecystectomy显示文摘 | Thierry Labaille Jean Xavier Mazoit Xavier Paqueron Dominique Franco Dan Benhamou | 2002 | Anesthesia & Analgesia2002,,1: | 2 |
| 5 | Insulin resistance–associated hepatic iron overload显示文摘 | Michel-Henry Mendler Bruno Turlin Romain Moirand Anne-Marie Jouanolle Thierry Sapey Dominique Guyader Jean-Yves le Gall Pierre Brissot Véronique David Yves Deugnier | 1999 | Gastroenterology1999,,5: | 2 |
| 6 | Triple therapy in treatment-experienced patients with HCV-cirrhosis in a multicentre cohort of the French Early Access Programme (ANRS CO20-CUPIC) – NCT01514890<!-- Doctopic: VH -->显示文摘 | Christophe Hézode Hélène Fontaine Céline Dorival Dominique Larrey Fabien Zoulim Valérie Canva Victor de Ledinghen Thierry Poynard Didier Samuel Marc Bourlière Jean-Pierre Zarski Jean-Jacques Raabe Laurent Alric Patrick Marcellin Ghassan Riachi Pierre-Henr | 2013 | Journal of Hepatology2013,,: | 2 |
| 7 | Trans-catheter arterial chemoembolization as first-line treatment for hepatic metastases from endocrine tumors显示文摘 | Alain Roche Baragur V. Girish Thierry de Baère Eric Baudin Valérie Boige Dominique Elias Philippe Lasser Martin Schlumberger Michel Ducreux | 2003 | European Radiology2003,,1: | 2 |
| 8 | Liver fibrosis evaluation using real-time shear wave elastography: Applicability and diagnostic performance using methods without a gold standard显示文摘 | Thierry Poynard Mona Munteanu Elena Luckina Hugo Perazzo Yen Ngo Luca Royer Larysa Fedchuk Florence Sattonnet Raluca Pais Pascal Lebray Marika Rudler Dominique Thabut Vlad Ratziu | 2013 | Journal of Hepatology2013,,5: | 2 |
| 9 | Staging chronic hepatitis C in seven categories using fibrosis biomarker (FibroTest?) and transient elastography (FibroScan?)显示文摘 | Thierry Poynard Julien Vergniol Yen Ngo Juliette Foucher Mona Munteanu Wassil Merrouche Massimo Colombo Vincent Thibault Eugene Schiff Clifford A. Brass Janice K. Albrecht Marika Rudler Olivier Deckmyn Pascal Lebray Dominique Thabut Vlad Ratziu Victor de | 2013 | Journal of Hepatology2013,,: | 2 |
| 10 | Changes in Causes of Death Among Adults Infected by HIV Between 2000 and 2005: The “Mortalité 2000 and 2005” Surveys (ANRS EN19 and Mortavic)显示文摘 | Charlotte Lewden Thierry May Eric Rosenthal Christine Burty Fabrice Bonnet Dominique Costagliola Eric Jougla Caroline Semaille Philippe Morlat Dominique Salmon Patrice Cacoub Geneviève Chêne | 2008 | JAIDS Journal of Acquired Immune Deficiency Syndromes2008,,: | 1 |
| 11 | Impact of ethanol on the perception of wine odorant mixtures显示文摘 | Elodie Le Berre Boriana Atanasova Dominique Langlois Patrick Etiévant Thierry Thomas-Danguin | 2007 | Food Quality and Preference2007,,6: | 1 |
| 12 | Heat Transfer Modeling in Vacuum Insulation Panels Containing Nano-Porous Silicas:A Review显示文摘 | Mathias Bouquerel Thierry Duforestel Dominique Baillis Gilles Rusaouen | 2012 | Energy and Buildings2012,54,: | 1 |
| 13 | Residual stresses in surface induction hardening of steel: comparison between experiment and simulation 显示文摘 | Dominique C Thierry P L Philippe B | 2008 | Materials Science and Engineer2008,25,2: | 1 |
| 14 | Mass Transfer Modeling in Gas Barrier Envelopes for Vacuum Insulation Panels:A Review显示文摘 | Mathias Bouquerel Thierry Duforestel Dominique Baillis | 2012 | Energy and Buildings2012,55,: | 1 |
| 15 | Cloning of a lactate dehydrogenase gene from Lacto-bacillus delbrueckii subsp, bulgaricus by complementation in Escherichia coli显示文摘 | Nathalie Bernard Thierry Ferain Dominique Garmyn | 1991 | Febs Letters1991,6164,: | 1 |
| 16 | Triple therapy in treatment-experienced patients with HCV-cirrhosis in a multicentre cohort of the French Early Access Programme (ANRS CO20-CUPIC) – NCT01514890<!-- Doctopic: VH -->显示文摘 | Christophe Hézode Hélène Fontaine Céline Dorival Dominique Larrey Fabien Zoulim Valérie Canva Victor de Ledinghen Thierry Poynard Didier Samuel Marc Bourlière Jean-Pierre Zarski Jean-Jacques Raabe Laurent Alric Patrick Marcellin Ghassan Riachi Pierre-Henr | 2013 | Journal of Hepatology2013,,: | 1 |
| 17 | Pentoxifylline Does Not Decrease Short-term Mortality but Does Reduce Complications in Patients With Advanced Cirrhosis显示文摘 | Didier Lebrec Dominique Thabut Frederic Oberti Jean–Marc Perarnau Bertrand Condat Helene Barraud Faouzi Saliba Nicolas Carbonell Philippe Renard Marie–Jose Ramond Richard Moreau Thierry Poynard | 2010 | Gastroenterology2010,,5: | 1 |
| 18 | A simple route towards low-temperature processing of nanoporous thin films using UV-irradiation: Application for dye solar cells显示文摘 | Zoe Tebby Odile Babot Dominique Michau Lionel Hirsch Luis Carlos Thierry Toupance | 2009 | Journal of Photochemistry & Photobiology A: Chemistry2009,,1: | 1 |
| 19 | Aortic valve repair by cusp extension with the use of fresh autologous pericardium in children with rheumatic aortic insufficiency显示文摘 | Afksendiyos Kalangos Maurice Beghetti Ary Baldovinos Dominique Vala Thierry Bichel Bernadette Mermillod Nicolas Murith Ingrid Oberhansli Beat Friedli Bernard Faidutti | 1999 | The Journal of Thoracic and Cardiovascular Surgery1999,,2: | 1 |
| 20 | Alternating mixing tabs in multiunctional heat exchanger-reactor 显示文摘 | Charbel Habchi Thierry Lemenand Dominique Della Valle Hassan Peerhossaini | 2010 | Chemical Engineering and Processing Process Intensification2010,49,: | 1 |