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| 1 | High-Resolution Genome-wide Association Study Identifies Genomic Regions and Candidate Genes for Important Agronomic Traits in Wheat显示文摘Wheat(Triticum aestivum)is a major staple food crop worldwide.Genetic dissection of important agronomic traits is essential for continuous improvement of wheat yield to meet the demand of the world's growing population.We conducted a large-scale genome-wide association study(GWAS)using a panel of 768 wheat cultivars that were genotyped with 327609 single-nucleotide polymorphisms generated by genotyping-by-sequencing and detected 395 quantitative trait loci(QTLs)for 12 traits under 7 environments.Among them,273 QTLs were delimited to≤1.0-Mb intervals and 7 of them are either known genes(Rht-D,Vrn-B1,and Vrn-D1)that have been cloned or known QTLs(TaGA2ox8,APO1,TaSus1-7B,and Rht12)that were previously mapped.Eight putative candidate genes were identified for three QTLs that enhance spike seed setting and grain size using gene expression data and were validated in three bi-parental populations.Protein sequence analysis identified 33 putative wheat orthologs that have high identity with rice genes in QTLs affecting similar traits.Large r^2 values for additive effects observed among the QTLs for most traits indicated that the phenotypes of these identified QTLs were highly predictable.Results from this study demonstrated that significantly increasing GWAS population size and marker density greatly improves detection and identification of candidate genes underlying a QTL,solidifying the foundation for large-scale QTL fine mapping,candidate gene validation,and developing functional markers for genomics-based breeding in wheat. | Yunlong Pang Chunxia Liu Danfeng Wang Paul St.Amand Amy Bernardo Wenhui Li Fang He Linzhi Li Liming Wang Xiufang Yuan Lei Dong Yu Su Huirui Zhang Meng Zhao Yunlong Liangi Hongze Jia Xitong Shen Yue Lu Hongming Jiang Yuye Wu Anfei Li Honggang Wang Lingrang Kong Guihua Bai Shubing Liu | 2020 | Molecular Plant2020，13，9： | 8 |
| 2 | Progress on sensors based on nanomaterials for rapid detection of heavy metal ions显示文摘The heavy metal ions,especially Cd^(2+),Pb^(2+) and Hg^(2+),show extremely hazard to the environment and human being.The measurement of heavy metal ions using sensors is catching more and more attention for its advantages of high sensitivity and selectivity,low-cost,convenience to handle and rapid detection.In recent years,nanomaterials such as gold nanoparticles(NPs),magnetic nanoparticles,graphene and nanocomposite materials are applied in sensors for improving sensitivity and selectivity,making the research on electrochemical(EC) sensors,spectrometric biosensors and colorimetric biosensors become a hot spot in the application to investigate heavy metal ions,in particular,Cd^(2+),Pb^(2+) and Hg^(2+).In this short review,the research of advanced detection of Cd^(2+),Pb^(2+) and Hg^(2+) and its progress based on nanomaterial sensors in recent years is reviewed. | Yuan Liu Yan Deng Hongming Dong Keke Liu Nongyue He | 2017 | Science China Chemistry2017，60，3： | 6 |
| 3 | Influence of CeO2 loading on structure and catalytic activity for NH3-SCR over TiO2-supported CeO2显示文摘A series of supported CeO2/TiO2 catalysts were prepared to explore the influence of CeO2 loading on these catalysts for the selective catalytic reduction of NO3 by NH3(NH3-SCR).The catalysts were investigated in detail by means of XRD,Raman,H2-TPR,NH3-TPD,XPS,in situ DRIFTS,and NH3-SCR reaction.The activity of the catalyst is closely related to the content of CeO2.When the loading of CeO2 is near the dispersion capacity(1.16 mmol Ce4+/100 m^2 TiO2),the catalytic activity is better.This may be because that the dispersed CeO2 is the active species and the catalyst has appropriate redox property,along with the larger amounts of surface Ce content and surface adsorbed oxygen species.Finally,a possible reaction mechanism via the Langmuir-Hinshelwood(L-H)mechanism is tentatively proposed to further understand the NH3-SCR reaction. | Hongliang Zhang Long Ding Hongming Long Jiaxin Li Wei Tan Jiawei Ji Jingfang Sun Changjin Tang Lin Dong | 2020 | Journal of Rare Earths2020，38，8： | 5 |
| 4 | Coordinated Demand Response of Rail Transit Load and Energy Storage System Considering Driving Comfort显示文摘Electric trains typically travel across the railway networks in an inter-provincial,inter-city and intra-city manner.The electric train generally serves as a load/source in tractive/brake mode,through which power networks and railway networks are closely coupled and mutually influenced.Based on the operational mode of rail trains and the characteristics of their load power,this paper proposes a coordinated optimal decisionmaking method of demand response for controllable load of rail trains and energy storage systems.First,a coordinated approach of dynamically adjusting the load of the controllable rail train in considering the driving comfort and energy storage battery is designed.Secondly,under the time conditions that satisfy the train’s operational diagram,the functional relationship between the train speed and the load power is presented.Based on this,in considering the constraints of the train’s arrival time,driving speed,motor power,and driving comfort,the capacity of energy storage batteries and other constraints,an optimization model for demand response in managing the traction power supply system under a two-part price and time-of-use(TOU)price is proposed.The objective is to minimize the energy consumption costs of rail transit trains,and optimize the speed trajectory of rail trains,the load power of traction system,and the output of energy storage batteries. | Hongming Yang Wangda Shen Qian Yu Junpeng Liu Yizhe Jiang Emmanuel Ackom Zhao Yang Dong | 2020 | CSEE Journal of Power and Energy Systems2020，6，4： | 4 |
| 5 | Can semipermeable membranes coating materials influence in vivo performance for paliperidone tri-layer ascending release osmotic pump tablet:In vitro evaluation and in vivo pharmacokinetics study显示文摘One purpose of this study was to develop a paliperidone(PAL)tri-layer ascending release pushepull osmotic pump(TA-PPOP)tablet which could meet the needs of clinical applications.And another purpose was to investigate whether different coating materials influenced in vivo performance of TA-PPOP.The ascending release mechanism of this trilayer delivery system on theory was elaborated.TA-PPOP was prepared by means of coating with cellulose acetate(CA)or ethyl cellulose(EC).Several important influence factors such as different core tablet compositions and different coating solution ingredients involved in the formulation procedure were investigated.The optimization of formulation and process was conducted by comparing different in vitro release behaviors of PAL.In vitro dissolution studies indicated that both the two formulations of different coating materials were able to deliver PAL at an ascending release rate during the whole 24 h test.The in vivo pharmacokinetics study showed that both self-made PPOP tablets with different coating had a good in vitro-in vivo correlation(IVIVC)and were bioequivalent with the brand product,which demonstrated no significant influence of the coating materials on the in vivo release acceleration of TA-PPOP. | Guangjing Li Yongjun Wang Hongming Chen Donglei Leng Panqin Ma Yanjie Dong Lifang Gao Zhonggui He | 2015 | Asian Journal of Pharmaceutical Sciences2015，10，2： | 4 |
| 6 | Hydrothermal synthesis and characterization of rare-earth ruthenate pyrochlore compounds R_2Ru_2O_7(R=Pr_(3+),Sm(3+)-Ho(3+))显示文摘A series of pyrochlore oxides, R2Ru2O7 (R=Pr3+, Sm3+–Ho3+) were synthesized under mild hydrothermal conditions. All the samples crystallize in uniform octahedron characteristically. The products were characterized by powder X-ray diffraction, scanning electron microscopy, energy-disperse X-ray spectroscopy, and dc susceptibility, and the factors that affected the crystallization were discussed. It was found that the purity of products depends strongly on the raw materials and the amount of alkalinity in the initial reaction mixtures. The ZFC and FC susceptibilities of all of the compounds R2Ru2O7 at low temperature were also measured and discussed. | YAO LinRan, WANG Dong, PENG Wen, HU WeiWei, YUAN HongMing & FENG ShouHua State key Laboratory of Inorganic Synthesis and Preparative Chemistry College of Chemistry, Jilin University, Changchun 130023, China | 2011 | Science China Chemistry2011，54，6： | 3 |
| 7 | Current Density Distribution in Double-Sided GTAW Process显示文摘A three dimensional current density distribution in double-sided gas tungsten arc welding (GTAW) proces is performed. The current density distribution field is evaluated by numerically solving Maxwell equations in the domain of the workpiece. In the boundary condition, the current density on. the workpiece surface is assumed as Gaussian distribution. Results show that the current distribution in DSAW is different from single side arc welding, it is more concentrated and the relative location of the two torches influence the current distribution greatly. | Hongming GAO Lin WU and Honggang DONG National Key Laboratory of Advanced Welding Production Technology, Harbin institute of Technology, Harbin 150001, China | 2001 | Journal of Materials Science & Technology2001，17，1： | 2 |
| 8 | Corrosion formation and phase transformation of nickel-iron hydroxide nanosheets array for efficient water oxidation显示文摘Designing earth-abundant electrocatalysts with high performance towards water oxidation is highly decisive for the sustainable energy technologies. This study develops a facile natural corrosion approach to fabricate nickel-iron hydroxides for water oxidation. The resulted electrode demonstrates an outstanding activity and stability with an overpotential of 275 mV to deliver 10 mA·cm^(−2). Experimental and theoretical results suggest the corrosion-induced formation of hydroxides and their transformation to oxyhydroxides would account for this excellent performance. This work not only provides an interesting corrosion approach for the fabrication of excellent water oxidation electrode, but also bridges traditional corrosion engineering and novel materials fabrication, which would offer some insights in the innovative principles for nanomaterials and energy technologies. | Lanqian Gong Huan Yang Hongming Wang Ruijuan Qi Junlei Wang Shenghua Chen Bo You Zehua Dong Hongfang Liu Bao Yu Xia | 2021 | Nano Research2021，14，12： | 2 |
| 9 | Multi-objective Distributed Wind Generation Planning in an Unbalanced Distribution System显示文摘In addition to increasing penetration of distributed generation(DG),the distribution system power flow may be significantly impacted by direction and magnitude.This paper proposes a method for optimal placement of wind DG considering the unbalanced operation of distribution systems.The objective function includes static voltage stability index,three-phase unbalance index,system reliability index,and DG investment cost.The untransposed distribution lines and unbalanced load are modelled,and corresponding static voltage stability index and system reliability considering DG penetrations are derived.The expected and stochastic daily distributed generation and demand profiles in four seasons are calculated to improve the accuracy.To solve this multi-objective optimization model,a fuzzy membership function is used to integrate the four individual objectives,and a sensitivity-based method is proposed to solve the model efficiently.Case study on IEEE 13-bus distribution 3-phase networks and 123-node test feeder successfully verifies the performance of the proposed approach. | Yu Zheng Zhao Yang Dong Ke Meng Hongming Yang Mingyong Lai Kit Po Wong | 2017 | CSEE Journal of Power and Energy Systems2017，3，2： | 2 |
| 10 | Nutritional evaluation of whole soybean curd made from different soybean materials based on amino acid profiles显示文摘Objectives:Amino acid profiles of whole soybean curds(WSCs)and conventional soybean curds(CSCs)were comparatively studied to 1.,evaluate their nutritional value and 2.,study the suitable soybean material to fabricate WSCs.Materials and Methods:Nine types of soybean materials were selected to make WSCs and CSCs.Protein digestibility-corrected amino acid score(PDCAAS)and principal component analysis were selected to perform the comparative analysis of amino acid profiles of the products.Results:Total contents of amino acids in WSCs and CSCs were 41.24-54.87 mg/g and 27.77-36.82 mg/g.Content ranges of essential amino acids were 13.59-19.38 mg/g and 8.46-11.76 mg/g for WSCs and CSCs.The essential amino acid pattern of WSCs was basically close to amino acid pattern spectrum requirements except valine and sulfur amino acids.As a limiting amino acid,methionine represented less than 0.4 for PDCAAS in all soybean curds except WSCs made from relay-cropping Nandou12 and Nandou25.Conclusions:The overall quality of amino acids in WSCs was higher than that in CSCs,indicating that WSCs indeed exhibited higher nutritional value than CSCs from the viewpoint of amino acid profile.WSCs with the high nutritional value could be made using Nandou25 and relay-cropping Nandou12 as materials. | Meili Li Hongming Dong Dingtao Wu Hong Chen Wen Qin Weiguo Liu Wenyu Yang Qing Zhang | 2020 | Food Quality and Safety2020，4，1： | 2 |
| 11 | Current Density Distribution in Gas Tungsten Arc Welding Process显示文摘Heat transfer and fluid flow in a weld pool had been simulated for several decades, which underwent from theoretically analysis to numerical solutions. Because of the complexity of the welding process, many ideal assumptions were made to simplify the question. This makes the solution somewhat not complied with the practical conditions. In previous papers, the current distribution in the weld pool is assumed as axi-symmetrical, and so does the electromagnetic forces, which plays an important role in determining the fluid flow field. Actually the current distribution is different from the assumption. In this paper; a three dimensional current distribution in Gas Tungsten Arc Welding (GTAW) process is performed. The current density distribution field is evaluated by numerically solving Maxwell’s equations in the domain of the workpiece. In the boundary condition, the current density on the top surface is assumed as Gaussian distribution. Results show that the current distribution in GTAW is not axi-symmetrical, and the relative location of the torch and the earth clamp influence the current distribution greatly. | Hongming GAO Lin WU Honggang DONG National Key Laboratory of Advanced Welding Production Technology, Harbin Institute of Technology, Harbin, 150001, China | 2000 | Journal of Shanghai Jiaotong university(Science)2000，5，1： | 2 |
| 12 | Electronic structure and optical properties of the Co-dopedanatase TiO2 studied from first principles显示文摘 | Weng Hongming Yang Xiaoping Dong Jinming | 2004 | Phys Rev B2004，69，12： | 1 |
| 13 | Therapeutic silencing miR-146b-5p improves cardiac remodeling in a porcine model of myocardial infarction by modulating the wound reparative phenotype显示文摘Fibrotic remodeling is an adverse consequence of immune response-driven phenotypic modulation of cardiac cells following myocardial infarction(Ml).MicroRNA-146b(miR-146b)is an active regulator of immunomodulation,but its function in the cardiac inflammatory cascade and its clinical implication in fibrotic remodeling following Ml remain largely unknown.Herein,miR-146b-5p was found to be upregulated in the infarcted myocardium of mice and the serum of myocardial ischemia patients.Gain-and loss-of-function experiments demonstrated that miR-146b-5p was a hypoxia-induced regulator that governed the pro-fibrotic phenotype transition of cardiac cells.Overexpression of miR-146b-5p activated fibroblast proliferation,migration,and fibroblast-to-myofibroblast transition,impaired endothelial cell function and stress survival,and disturbed macrophage paracrine signaling.Interestingly,the opposite effects were observed when miR-146b-5p expression was inhibited.Luciferase assays and rescue studies demonstrated that the miR-146b-5p target genes mediating the above phenotypic modulations included interleukin 1 receptor associated kinase 1(IRAKI)and carcinoembryonic antigen related cell adhesion molecule 1(CEACAM1).Local delivery of a miR-146b-5p antagomir significantly reduced fibrosis and cell death,and upregulated capillary and reparative macrophages in the infarcted myocardium to restore cardiac remodeling and function in both mouse and porcine Ml models.Local inhibition of miR-146b-5p may represent a novel therapeutic approach to treat cardiac fibrotic remodeling and dysfunction following Ml. | Yiteng Liao Hao Li Hao Cao Yun Dong Lei Gao Zhongmin Liu Junbo Ge Hongming Zhu | 2021 | Protein & Cell2021，12，3： | 1 |
| 14 | An experimental study of drop-on-demand drop formation 显示文摘 | DONG Hongming CARR Wallace W MORRIS Jeffrey F | 2006 | Physics of Fluids2006，18，7： | 1 |
| 15 | Temporally-Resolved Inkjet Drop Impaction on Surfaces 显示文摘 | Dong Hongming Wallance W C David G | 2007 | AIChE J2007，53，26： | 1 |
| 16 | Effect of AETiO 3 (AE=Mg, Ca, Sr) doping on dielectric and varistor characteristics of CaCu 3 Ti 4 O 12 ceramic prepared by the sol–gel process显示文摘 | Dong Xu Kai He Renhong Yu Lei Jiao Hongming Yuan Xiujuan Sun Guoping Zhao Hongxing Xu Xiaonong Cheng | 2014 | Journal of Alloys and Compounds2014，，： | 1 |
| 17 | Influence of zinc on electrical and microstructural properties of CaCu 3 Ti 4 O 12 ceramics prepared by sol–gel process显示文摘 | Dong Xu Chen Zhang Yuanhua Lin Lei Jiao Hongming Yuan Guoping Zhao Xiaonong Cheng | 2012 | Journal of Alloys and Compounds2012，，： | 1 |
| 18 | Microstructure and electrical properties of Y(NO 3 ) 3 ·6H 2 O-doped ZnO–Bi 2 O 3 -based varistor ceramics显示文摘 | Dong Xu Xiaonong Cheng Hongming Yuan Juan Yang Yuanhua Lin | 2011 | Journal of Alloys and Compounds2011，，38： | 1 |
| 19 | An experimental study of drop-on-demand drop formation显示文摘 | DONG Hongming CARR Wallace W MORRIS Jeffrey F | 2006 | Physics of Fluids2006，18，7： | 1 |
| 20 | Rapid identification of diarrheagenic Escherichia coli based on barcoded magnetic bead hybridization显示文摘Diarrhea,as a global public health problem,causes a large number of infections and deaths every year.Although Escherichia coli(E.coli)is one of the normal flo ra microorganisms in the human intestinal tract,it has five pathogenic bacteria types that can cause human diarrhea,known as diarrheagenic E.coli.When people are infected,rapid and accurate diagnosis,along with timely treatment,are especially important.Here,we introduce a new method to identify and analyze a large number of pathogenic strains in E.coli by multiplex PCR and barcoded magnetic bead hybridization.Results show that the detection sensitivities of enterohemorrhagic E.coli,enterotoxigenic E.coli,enteropathogenic E.coli,enteroinvasive E.coli and enteroaggregative E.coli were 1.3×10^3 CFU/mL,2×10^4 CFU/mL,4×10^4 CFU/mL,7.2×10^4 CFU/mL and 1.7 CFU/mL respectively.This method has strong specificity and high sensitivity and detects multiple target sequences in one experiment.Compared with other methods,BMB array has great application potential. | Hongming Dong Congli Tang Ziyu He Hongmei Liu Yuyue Xu Hao Huang Gaojian Yang Ziqi Xiao Song Li Yan Deng Zhu Chen Hui Chen Zuodong Qin Yasser Perera Negrin Nongyue He | 2020 | Chinese Chemical Letters2020，31，7： | 0 |
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