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15篇 您的检索式:作者名="ELOISA A"
    题名 作者 年代 出处 被引量
1Stem cell factor in mast cells and increased mast cell density in idiopathic and ischemic cardiomyopathy显示文摘Vincenzo P Isabella M Eloisa A Barbel LS Laura V Monika A 1998Am Heart Assoc1998,97,10:1
2Chemical Composition and Larvicidal Activity of Essential Oils Extracted from Brazilian Legal Amazon Plants against Aedes aegypti L. (Diptera: Culicidae)显示文摘Clarice Noleto Dias Luciana Patrícia Lima Alves Klinger Antonio da Franca Rodrigues Maria Cristiane Aranha Brito Carliane dos Santos Rosa Flavia Maria Mendon?a do Amaral Odair dos Santos Monteiro Eloisa Helena de Aguiar Andrade José Guilherme Soares Maia 2015Evidence-Based Complementary and Alternative Medicine2015,,:1
3Aroma volatiles from two fruit varieties of jackfruit(ArtocarpusHeterophyllus Lam)显示文摘Jose Guilherme S Maia Eloisa Helena A Andrade Mariadas Gragas BZoghbi 2004Food Chemistry2004,85,:1
4Aroma volatile constituents of Brazilian varieties of mango fruit显示文摘ELOISA H A MARIA J G S 2000J Food Comp Anal2000,13,1:1
5Aroma volatile constituents of Brazilian varieties of mango fruit显示文摘Eloisa H A A Jose G S M Maria D G B Z 2000Journal of Food Composition and Analysis2000,13,:1
6Aroma Volatile Constituents of Brazilian Varieties of Mango Fruit显示文摘Eloisa Helena A Andrade Jose Guilherme 2000Journal of food composition and analysis2000,13,:1
7Aroma volatile constituents of Brazilian varieties of mango fruit 显示文摘Eloisa A Jose G S Maria das G B Z 2000J Food Comp Anal2000,13,1:1
8Aroma volatiles from 2 fruit ofjackfruit显示文摘Maia Jose Guilherme S Andrade Eloisa Helena A Zoghbi maria das Gracas B 2003FoodChemistry2003,85,2:1
9Aroma volatile constituents of Brazilian varieties of mango fruit 显示文摘Eloisa H A A Jose G S M Maria D G B Z 2000Journal of Food Composition and Analysis2000,13,:1
10Mechanisms of Disease: apoptosis in heart failure-seeing hope in death 显示文摘Jagat N Nezam H Eloisa A 2006Nature Clinical Practice Cardiovascular Medicine2006,3,:1
11Mitochondrial DNA mutations and mitochondrial abnormalities in dilated cardiomyopathy显示文摘ELOISA A MARTA D ROBERTA F 1998Am J Pathol1998,153,:1
12Identification of sixty-two novel and twelve known FBN1 mutations in eighty-one unrelated probands with Marfan syndrome and other fibrillinopathies 显示文摘Eloisa A Maurizia G Silvia A 2005Hum Mutat2005,26,5:1
13Aroma volatiles from two fruit varieties of jackfruit(ArtocarpusHeterophyllus Lam)显示文摘Jose Guilherme S Maia Eloisa Helena A Andrade Mariadas Gragas BZoghbi 2004Food Chemistry2004,85,:1
14Aroma volatile constituents of Brazilian varieties of mango fruit显示文摘ELOISA H A A JOSE G S M MARIA D G B Z 2000Journal of Food Composition and Analysis2000,13,1:1
15Biological insights in non-small cell lung cancer显示文摘Lung oncogenesis relies on intracellular cysteine to overcome oxidative stress.Several tumor types,including non-small cell lung cancer(NSCLC),upregulate the system x-c cystine/glutamate antiporter(xCT)through overexpression of the cystine transporter SLC7A11,thus sustaining intracellular cysteine levels to support glutathione synthesis.Nuclear factor erythroid 2-related factor 2(NRF2)serves as a master regulator of oxidative stress resistance by regulating SLC7A11,whereas Kelch-like ECH-associated protein(KEAP1)acts as a cytoplasmic repressor of the oxidative responsive transcription factor NRF2.Mutations in KEAP1/NRF2 and p53 induce SLC7A11 activation in NSCLC.Extracellular cystine is crucial in supplying the intracellular cysteine levels necessary to combat oxidative stress.Disruptions in cystine availability lead to iron-dependent lipid peroxidation,thus resulting in a type of cell death called ferroptosis.Pharmacologic inhibitors of xCT(either SLC7A11 or GPX4)induce ferroptosis of NSCLC cells and other tumor types.When cystine uptake is impaired,the intracellular cysteine pool can be sustained by the transsulfuration pathway,which is catalyzed by cystathionine-B-synthase(CBS)and cystathionine g-lyase(CSE).The involvement of exogenous cysteine/cystine and the transsulfuration pathway in the cysteine pool and downstream metabolites results in compromised CD8^(+)T cell function and evasion of immunotherapy,diminishing immune response and potentially reducing the effectiveness of immunotherapeutic interventions.Pyroptosis is a previously unrecognized form of regulated cell death.In NSCLCs driven by EGFR,ALK,or KRAS,selective inhibitors induce pyroptotic cell death as well as apoptosis.After targeted therapy,the mitochondrial intrinsic apoptotic pathway is activated,thus leading to the cleavage and activation of caspase-3.Consequently,gasdermin E is activated,thus leading to permeabilization of the cytoplasmic membrane and cell-lytic pyroptosis(indicated by characteristic cell membrane ballooning).Breakthroughs in KRAS G12C allele-specific inhibitors and potential mechanisms of resistance are also discussed herein.Rafael Rosell Anisha Jain Jordi Codony-Servat Eloisa Jantus-Lewintre Blake Morrison Jordi Barretina Ginesta María González-Cao 2023Cancer Biology & Medicine2023,20,7:0
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