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12019新型冠状病毒基因组特征和流行病学:病毒起源和受体结合的意义显示文摘研究者对来自9例新型冠状病毒肺炎住院患者的支气管肺泡灌洗液样本和培养的分离株进行了下一代测序。从这些个体中获得了严重急性呼吸综合征-冠状病毒2(severe acute respiratory syndrome-coronavirus 2,SARS-CoV-2)的完整和部分基因组序列。利用Sanger测序连接病毒重叠群以获得全长基因组,cDNA末端快速扩增确定终端区。对这些SARSCoV-2基因组和其他冠状病毒基因组进行了系统进化分析,以确定该病毒的进化史并有助于推断其可能的起源。刘青(译) 刘莉(审校) Lu R Zhao X Li J Niu P Yang B Wu H Wang W Song H Huang B Zhu N Bi Y Ma X Zhan F Wang L Hu T Zhou H Hu Z Zhou W Zhao L Chen J Meng Y Wang J Lin Y Yuan J Xie Z Ma J Liu WJ Wang D Xu W Holmes EC Gao GF Wu G Chen W Shi W Tan W 2020中华高血压杂志2020,28,3:516
2急性脊髓损伤患者治疗的临床操作指南:关于MRI基线在临床治疗决策与结果预测中作用的几点建议(英文)显示文摘The objective of this guideline is to outline the role of magnetic resonance imaging(MRI) in clinical decision making and outcome prediction in patients with traumatic spinal cord injury(SCI).Methods A systematic review of the literature was conducted to address key questions related to the use of MRI in patients with traumatic SCI.This review focused on longitudinal studies that controlled for baseline neurologic status.A multidisciplinary Guideline Development Group(GDG) used this information,their clinical expertise,and patient input to develop recommendations on the use of MRI for SCI patients.Based on GRADE(Grading of Recommendation,Assessment,Development and Evaluation),a strong recommendation is worded as ' we recommend,' whereas a weaker recommendation is indicated by 'we suggest.' Results Based on the limited available evidence and the clinical expertise of the GDG,our recommendations were:(1) 'We suggest that MRI be performed in adult patients with acute SCI prior to surgical intervention,when feasible,to facilitate improved clinical decision-making'(quality of evidence,very low) and(2) 'We suggest that MRI should be performed in adult patients in the acute period following SCI,before or after surgical intervention,to improve prediction of neurologic outcome '(quality of evidence,low).Conclusions These guidelines should be implemented into clinical practice to improve outcomes and prognostication for patients with SCI.Fehlings MG Martin AR Tetreault LA Aarabi B Anderson P Arnold PM Brodke D Burns AS Chiba K Dettori JR Furlan JC Hawryluk G Holly LT Howley S Jeji T Kalsi-Ryan S Kotter M Kurpad S Kwon BK Marino RJ Massicotte E Merli G Middleton JW Nakashima H Nagoshi N Palmieri K Singh A Skelly AC Tsai EC Vaccaro A Wilson JR Yee A Harrop JS 2017中华神经外科疾病研究杂志2017,16,6:8
3The angiotensin-re- ceptor blocker candesartan for treatment of acute stroke (SCAST) : a randomised, placebo-controlled, double-blind tri- al显示文摘Sandset EC Philip MW Boysen G 2011Lancet2011,377,9767:1
4Interfere-inducible gene expression signaturein peripheral blood cells of patients with severe lupus 显示文摘Baechler EC Batliwalla FM Karypis G 2003Proc Natl Acad Sci USA2003,100,5:1
5Profiling of complex microbial populations by denaturing gradient gel electrophoresis analysis of polymerase chain reaction amplified genes coding for 16S rRNA 显示文摘Muyzer G Dewaal EC Uitterlinden AG 1993Appl Environ Microbio1993,59,3:1
6Protein expression profiling of endometrial malignancies reveals a new tumor marker:chaperonin 10显示文摘Yang EC Guo J Diehl G 2004J Proteome Res2004,3,3:1
7Profiling of complex microbial populations by denaturing gradient gel electrophoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA显示文摘Muyzer G de Waal EC Uitterlinden AG 1993Appl Environ Microbiol1993,59,:1
8Antidepressant-like effects of the nociceptin/orphanin FQ receptor antagonist UFP-101:new evidence from rats and mice 显示文摘Gavioli EC Vaughan CW Marzola G 2004Naunyn Schmiedebergs Arch Pharmacol2004,369,6:1
9Profiling of complex microbial populations by denaturing gradient gel electrophoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA显示文摘Muyzer G deWaal EC Uitterlinden AG 1993Applied and Environmental Microbiology1993,59,3:1
10Profiling of complex microbi- al populations by denaturing gTadient gel electrophoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA 显示文摘Muyzer G de Waal EC Uitterlinden AG 1993Appl Emiron Microbiol1993,59,3:1
11Mitochondrial reactive oxygen species regulate the temporal activation of nuclear factor kappaB to modulate turnout necrosis factor-induced apoptosis: evidence from mitochondria-targeted antioxidants显示文摘Hughes G Murphy MP Ledgerwoed EC 2005Biochem J2005,389,1:1
12Association of glutamine 27 polymorphism of 132 adrenoceptor with reported childhood asthma:population based study 显示文摘Hopes EC McDougall C Christie G 1998Br Med J1998,316,7132:1
13Activin A levels are associated with abnormal glucose regulation in patients with myocardial infarction:potential counteracting effecting of activin A on iinflammation显示文摘Andersen G Ueland T Knudsen EC 2011Didabetes2011,60,5:1
14Profiling of comp lex microbial population by denaturing gradient gel electrophoresis analysis of polymerase chain reaction amp lified genes encoding for 16S r RNA显示文摘Muyzer G Waal EC Uitterlinden AG 1993Appl Environ Microbiol1993,59,:1
15Profiling of complex microbial populations by denaturing gradient gel electrophoresis analysis of polymerase chain reaction amplified genes encoding for 16S Rrna显示文摘Muyzer G Waal EC Uitterlinden AG 1993Appl Environ Microbiol1993,59,:1
16The radiation dose response relationship in a human glioma xenograft and an evaluation of the influ- ence of glutat hione depletion by but hionine sulfoximine显示文摘Halperin EC Brizel DM Honore G 1992IntJ Radiat Oncol Biol Phys1992,24,:1
17Hypertension caused by chronic intermittent hypoxia-influence of chemoreceptors and sympathetic nervous system显示文摘Lesske J Fletcher EC Bao G 1997J Hypertens1997,15,122:1
18Renin activity and blood pressure in response to chronic episodic hypoxia显示文摘Fletcher EC Bao G Li R 1999Hypertension1999,34,:1
19Update on erythrodermic cutaneous T cell lymphoma: Report of the international society for cutaneous lymphoma 显示文摘VONDERHE1D EC BERNENGO MG BURG G 2002J Am Acad Dermatol2002,46,1:1
20Animal models of Parkinson's disease in rodents induced by toxins: an update 显示文摘Hirsch EC Hoglinger G Rousselet E 2003J Neural Transm Suppl2003,65,:1
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