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| 1 | Conduit necrosis following esophagectomy: An up-to-date literature review显示文摘Esophageal conduit ischaemia and necrosis is an uncommon but devastating complication of esophagectomy and remains one of the most challenging issues in surgical practice. The incidence, time interval to develop symptoms, and clinical presentation are highly variable with no predictable pattern. Evidence comes from case reports and case series rather than randomized controlled trials.We describe the issues surrounding conduit necrosis affecting the stomach,jejunum and colon as an esophageal replacement and the advantages,disadvantages and challenges of each type of reconstruction. Diagnosis is challenging for the most experienced surgeon. Upper gastrointestinal endoscopy and computed tomography thorax with both oral and intravenous contrast is the gold standard. Management, either conservative or interventional is also a difficult decision. Management options include conservative treatment and more aggressive treatments such as stent insertion, surgical debridement and repair of the esophagus using jejunum, colon or a musculocutaneous flap. In spite of recent advances in surgical techniques, there is no reliable strategy to manage esophageal conduit necrosis. Our review covers the pathophysiology and clinical significance of esophageal necrosis while highlighting current techniques of prevention, diagnosis and treatment of this life-threatening condition. | Antonios Athanasiou Mairead Hennessy Eleftherios Spartalis Benjamin H L Tan Ewen A Griffiths | 2019 | World Journal of Gastrointestinal Surgery2019，11，3： | 2 |
| 2 | Uterine prolapse complicating pregnancy显示文摘 | George D Elias L Eleftherios A | 2007 | Arch Gynecol Obstet2007，276，4： | 1 |
| 3 | Acute management of poorcondition suharachnoid hemorrhage patients显示文摘 | Carvi Y Nievas MN | 2007 | Vase HealthRisk Manag2007，3，6： | 1 |
| 4 | Tragasa Management of perprosthetic patellar fractures Asystematicreview of literatures 显示文摘 | BYRON E CHALIDIS A ELEFTHERIOS TSIRIDIS A | 2007 | Iniury Int J Care In- jured2007，38，： | 1 |
| 5 | Comparison of minimally invasive fusion and instrumentation versus open surgery for severe stenotic spondylolisthesis with high-grade facet joint osteoarthritis显示文摘 | Eleftherios A Mario C N | 2013 | Eur Spine2013，22，8： | 1 |
| 6 | Uterine prolapse complicating pregnancy显示文摘 | George D Elias L Eleftherios A | 2007 | Arch Gynecol Obstet2007，276，4： | 1 |
| 7 | Aroma investigation of unifloral Greek citrus honey using solid-phase microextraction coupled to gas chromatographicmass spectrometric analysis 显示文摘 | ELEFTHERIOS Alissandrakis TARANTILIS P A | 2007 | Food Chemistry2007，100，1： | 1 |
| 8 | Effect the fracture process zone in directed crack propagation in borehole blasting 显示文摘 | George E Zacharias A Eleftherios L | 1994 | SPE 280851994，，： | 1 |
| 9 | Uterine prolapse complicatingpregnancy显示文摘 | George D Elias L Eleftherios A | 2007 | Arch Gynecol Obstet2007，276，4： | 1 |
| 10 | The knee meniscus:structure-function,pathophysiology,current repair techniques,and prospects for regeneration显示文摘 | Eleftherios A Makris MD Pasha HBS | 2011 | Biomaterials2011，32，30： | 1 |
| 11 | Acute management of poor condition subarachnoid hemorrhage patients 显示文摘 | Eleftherios A Carvi Y Nievas MN | 2007 | Vase Health Risk Manag2007，3，6： | 1 |
| 12 | Control of spoilage microorganisms in minced pork by a self-developed modified atmosphere induced by the respiratory activity of meat microflora 显示文摘 | Konstantinos P Koutsoumanis Stamatiou A P Eleftherios H Drosinos | 2008 | Food Microbiology2008，25，： | 1 |
| 13 | Molecular Characterization of Two Clostridium acetobutylicum ATCC 824 Butanol Dehydrogenase Isozyme Genes 显示文摘 | Karl A W George N B Eleftherios T P | 1992 | Journal of Bacteriology1992，174，22： | 1 |
| 14 | Acute management of poor condition subarachnoid hemorrhage patients显示文摘 | Eleftherios A Carvi Y Nievas MN | 2007 | Vase Health Risk Manag2007，3，6： | 1 |
| 15 | Management of periprosthetic patellar fractures: A systematic review of literature 显示文摘 | Byron E Eleftherios T Adamantios A T | 2007 | Injury2007，38，6： | 1 |
| 16 | Acute esophageal necrosis: A systematic review and pooled analysis显示文摘BACKGROUND Acute esophageal necrosis(AEN)is a rare entity with multifactorial etiology,usually presenting with signs of upper gastrointestinal bleeding.AIM To systematically review all available data on demographics,clinical features,outcomes and management of this medical condition.METHODS A systematic literature search was performed with respect to the PRISMA statement(end-of-search date:October 24,2018).Data on the study design,interventions,participants and outcomes were extracted by two independent reviewers.RESULTS Seventy-nine studies were included in this review.Overall,114 patients with AEN were identified,of whom 83 were males and 31 females.Mean patient age was 62.1±16.1.The most common presenting symptoms were melena,hematemesis or other manifestations of gastric bleeding(85%).The lower esophagus was most commonly involved(92.9%).The most widely implemented treatment modality was conservative treatment(75.4%),while surgical or endoscopic intervention was required in 24.6%of the cases.Mean overall followup was 66.2±101.8 d.Overall 29.9%of patients died either during the initial hospital stay or during the follow-up period.Gastrointestinal symptoms on presentation[Odds ratio 3.50(1.09-11.30),P=0.03]and need for surgical or endoscopic treatment[surgical:Odds ratio 1.25(1.03-1.51),P=0.02;endoscopic:Odds ratio 1.4(1.17-1.66),P<0.01]were associated with increased odds of complications.A sub-analysis separating early versus late cases(after 2006)revealed a significantly increased frequency of surgical or endoscopic intervention(9.7%vs 30.1%respectively,P=0.04)CONCLUSION AEN is a rare condition with controversial pathogenesis and unclear optimal management.Although the frequency of surgical and endoscopic intervention has increased in recent years,outcomes have remained the same.Therefore,further research work is needed to better understand how to best treat this potentially lethal disease. | Dimitrios Schizas Nikoletta A Theochari Konstantinos S Mylonas Prodromos Kanavidis Eleftherios Spartalis Stamatina Triantafyllou Konstantinos P Economopoulos Dimitrios Theodorou Theodore Liakakos | 2020 | World Journal of Gastrointestinal Surgery2020，12，3： | 0 |
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