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| 1 | 汽车用钢的最新研究进展显示文摘为满足提高燃油效率及汽车'轻量化'等方面持续的需求,学术界及工业领域一直都很重视钢铁及其替代材料的研发,这两类材料之间的竞争始终十分激烈。对汽车用钢在北美的研究现状进行了概述,并重点介绍了几种冷轧和热轧汽车用钢的研究进展及其生产情况。新一代先进高强钢的发展将依然令人关注并充满机遇。 | John G Speer David K Matlock Emmanuel de Moor Grant A Thomas 周澍(译) 李晟(校) | 2013 | 世界钢铁2013，，5： | 10 |
| 2 | Favorable response to subcutaneous administration of infliximab in rats with experimental colitis显示文摘AIM: To investigate the influence of infliximab (Remicade)on experimental colitis produced by 2,4,6,trinitrobenzene sulfonic acid (TNBS) in rats.METHODS: Thirty-six Wistar rats were allocated into four groups (three groups of six animals each and a fourth of 12 animals). Six more healthy animals served as normal controls (Group 5). Group 1:colitis was induced by intracolonic installation of 25 mg of TNBS dissolved in 0.25 mL of 50% ethanol and infliximab was subcutaneously administered at a dose of 5 mg/kg BW; Group 2: colitis was induced and infliximab was subcutaneously administered at a dose of 10 mg/kg BW; Group 3: colitis was induced and infliximab was subcutaneously administered at a dose of 15 mg/kg BW; Group 4: colitis was induced without treatment with infliximab. Infliximab was administered on d 2-6. On the 7th d, all animals were killed. The colon was fixed in 10%buffered formalin and examined by light microscopy for the presence and activity of colitis and the extent of tissue damage. Tumor necrosis factor-alpha (TNF-α) and malondialdehyde (MDA) were also measured.RESULTS: Significant differences concerning the presence of reparable lesions and the extent of bowel mucosa without active inflammation in all groups of animals treated with infliximab compared with controls were found. Significant reduction of the tissue levels of TNF-α in all groups of treated animals as compared withthe untreated ones was found (0.47±0.44, 1.09±0.86,0.43±0.31 vs 18.73±10.53 respectively). Significant reduction in the tissue levels of MDA was noticed in group 1 as compared to group 4, as well as between groups 2 and 4.CONCLUSION: Subcutaneous administration of infliximab reduces the inflammatory activity as well as tissue TNF-α and MDA levels in chemical colitis in rats.Infliximab at a dose of 5 mg/kg BW achieves better histological results and produces higher reduction of the levels of TNF-α than at a dose of 10 mg/kg BW.Infliximab at a dose of 5 mg/kg BW produces higher reduction of tissue MDA levels than at a dose of 15 mg/kg BW. | John K Triantafillidis Apostolos E Papalois Aikaterini Parasi Emmanuel Anagnostakis Stavros Burnazos Aristofanis Gikas Emmanuel G Merikas Emmanuel Douzinas Maria Karagianni Helen Sotiriou | 2005 | World Journal of Gastroenterology2005，11，43： | 5 |
| 3 | Saccharomyces boulardii Does Not Prevent Relapse of Crohn’s Disease显示文摘 | Arnaud Bourreille Guillaume Cadiot Gérard Le Dreau David Laharie Laurent Beaugerie Jean–Louis Dupas Philippe Marteau Patrick Rampal Dominique Moyse Ashraf Saleh Marie–Emmanuelle Le Guern Jean–Paul Galmiche | 2013 | Clinical Gastroenterology and Hepatology2013，，8： | 3 |
| 4 | Human intestinal parasitism,potable water availability and methods of sewage disposal among nomadic Fulanis in Kuraje rural settlement of Zamfara state显示文摘Objective:To ascertain the level of intestinal parasites vis-a-vis the quality of housing and water supply,and sanitary conditions among the people of Kuraje village in Zamfara state. Methods:The study was cross sectional in nature.Individual households were selected using systematic random sampling methods and pre-tested questionnaires were administered to all the members of each household.Stool samples were collected and processed using standard laboratory procedures.Housing conditions,sources of water and sanitary conditions of the households were also inspected.Results were analysed using Epi Info 2006 model.Results: The prevalence of intestinal parasites was 67.0%(347/519).72.3%(251/347),17.0%(59/347),and 10.7%(37/347) had one,two and three or more parasites,respectively.The associated factors with intestinal parasites were poor housing and sanitary conditions,lack of potable water and illiteracy.The commonest parasites encountered were hookworm(22.0%),Ascaris lumbricoides (18.5%),and Strongyloides stercoralis(15.6%) while the least common was Enterobius vermicularis (1.6%).Others were Giardia lamblia(5.7%),Hymenolepsis nana(5.0%),Trichuris trichiura(8.8%), Entamoeba histolytica(14.4%) and Schistosoma mansoni(8.4%).Conclusions:The infection rate of intestinal parasites in Kuraje village is high.More efforts should be intensified towards improvement in sanitary and housing standards,supply of potable water and institution of a more comprehensive literacy programme for the people of the community. | Godwin T Jombo James G Damen Hauwa Safiyanu Friday Odey Emmanuel M Mbaawuaga | 2010 | Asian Pacific Journal of Tropical Medicine2010，3，6： | 2 |
| 5 | Cystathionine β Synthase Deficiency Promotes Oxidative Stress, Fibrosis, and Steatosis in Mice Liver显示文摘 | Karine Robert Johnny Nehmé Emmanuel Bourdon Gérard Pivert Bertrand Friguet Claude Delcayre Jean–Maurice Delabar Nathalie Janel | 2005 | Gastroenterology2005，，5： | 2 |
| 6 | Activation of Notch-Mediated Protective Signaling in the Myocardium显示文摘 | Gude NA Emmanuel G Wu W | 2008 | Circ Res2008，102，9： | 1 |
| 7 | PRDX4,a member of the peroxiredoxin family,is fused to AML1 (RUNX1) in an acute myeloid leukemia patient with a t (X;21)(p22:q22)显示文摘 | Zhang Y Emmanuel N Kamboj G | 2004 | Genes Chromosomes Cancer2004，40，4： | 1 |
| 8 | Erythromycin for the treatment of chronic intestinal pseudo-obstruction: description of six cases with a positive response显示文摘 | Emmanuel A V Shand A G Kamm M A | 2004 | Aliment Pharmacol Ther2004，19，6： | 1 |
| 9 | Activation of Notch-media- ted protective signaling in the myocardium 显示文摘 | Gude NA Emmanuel G Wu W | 2008 | Circ Res2008，102，9： | 1 |
| 10 | Analytical far-field divergence angle of a truncated Gaussian beam显示文摘 | Emmanuel M Drvge Neal G Skinner Dale M Byrne | 2000 | Appl Opt2000，39，27： | 1 |
| 11 | Production of recombinant Potato mop-top virus coat protein in Escherichia coli and generation of antisera recognizing native virus protein 显示文摘 | Valerie H Emmanuel J Maryse G | 2003 | Journal of Virology Methods2003，110，： | 1 |
| 12 | Triple-negative breastcancer: histoclinical and molecular features, therapeutic managementand perspectives显示文摘 | Antony G Renaud S Emmanuelle CJ | 2013 | Bull Cancer2013，100，5： | 1 |
| 13 | Rapid silver staining and recovery of PCR products separated on polyacrylamide gels显示文摘 | Carlos J S Emmanuel D N Andrew F G | 1994 | Biotechniques1994，17，5： | 1 |
| 14 | Evaluation of a rapid diagnostic test (CareStartTM Malaria HRP-2/pLDH (Pf/pan) Combo test) for the diagnosis of malaria in reference setting显示文摘 | Jessica M Philippe G Emmanuel B | 2010 | Malar J2010，，9： | 1 |
| 15 | Synthesis and char acterization of unsaturated polyester and phenolic resin nanocomposites显示文摘 | Jongdoo L Emmanuel P G | 1997 | Polymer Preprint1997，38，2： | 1 |
| 16 | Robust automatic pa- rallel parking in tight spaces via fuzzy logic 显示文摘 | Zhao Y N Emmanuel G Collins Jr | 2005 | Robotics and Autonomous Systems2005，51，23： | 1 |
| 17 | Dexmnetha sone improves vascular hyporeactivity induced by LPS in vivo by medu lating ATP-sensitive potassium channels activity 显示文摘 | d' Emmanuele di Villa Bianca R Lippolis L Autore G | 2003 | Br J Pharmacol2003，140，1： | 1 |
| 18 | The effect of density on sea bass (Dicentrarchus labrax ) performance in a tank-based recirculating system显示文摘 | SOPHIE S EMMANUELLE R ERIC G | 2009 | Aquacuhural Engineering2009，40，2： | 1 |
| 19 | Feeding high proportions of barley grain stimulates an inflammatory response in dairy cows 显示文摘 | EMMANUEL D G DUNN S M AMETAJ B N | 2008 | J Dairy Sci2008，91，2： | 1 |
| 20 | Fluoroquinolone resistance associated with target mutation and active effiux in oropharyngeal isolates of viridans group Streptococci 显示文摘 | FRANCOIS G EMMANUELLE V ANNIE B H | 2000 | Antimicro Agents Chemother2000，44，8： | 1 |
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