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361篇 您的检索式:作者名="FOX C A"
    题名 作者 年代 出处 被引量
1最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL 2014神经病学与神经康复学杂志2014,11,3:31
2DNA damage induced by chronic inflammation contributes to colon carcinogenesis in mice显示文摘Meira Lisiane B Bugni James M Green Stephanie L Lee Chung-Wei Pang Bo Borenshtein Diana Rickman Barry H Rogers Arlin B Moroski-Erkul Catherine A McFaline Jose L Schauer David B Dedon Peter C Fox James G Samson Leona D 2008Journal of Clinical Investigation2008,,7:2
3基于一个大型随机试验预测稳定性心绞痛队列患者死亡、心肌梗死和卒中的危险评分显示文摘目的对需要抗心绞痛治疗并且左心室功能代偿症状稳定的心绞痛患者建立预测全因死亡、心肌梗死和导致致残性卒中的复合危险评分。设计大型多中心临床试验数据的多变量Cox回归分析。背景西欧、以色列、加拿大、澳大利亚和新西兰的心脏专科门诊患者。入选者7311例具有全部需要资料的患者被入选。主要结局的测量指标平均随访4.9年时间内所有原因的死亡、心肌梗死或者致残性卒中。结果1063例患者发生任何原因死亡或者持久性心肌梗死或者致残性卒中。这些复合终点的5年危险性在危险性最低的十分位患者为4%,而在危险性最高的十分位患者为35%。危险评分结合16项临床常规变量的降序排序是:年龄、左心室射血分数、吸烟、白细胞计数、糖尿病、随机血糖浓度、肌酐浓度、既往卒中病史、1周至少1次心绞痛发作、冠状动脉造影发现(如果能够获得)、降脂治疗、QT间期、收缩期血压≥150mmHg、抗心绞痛药物数量、陈旧性心肌梗死以及性别。把这个模型分别应用于任何原因所致的死亡、心肌梗死和卒中进行预测评估,所得的结果相似。危险评分似乎不能预测事件性质(39%的死亡、46%心肌梗死以及15%致残性卒中)或者冠状动脉造影或血管重建率(占29%的患者)。结论该危险评分对客观地决定稳定性心绞痛患者进一步治疗措施以减少重要预后事件发生是有帮助的。该危险评分同样可以用于将来的计划性试验。Tim C Clayton Stuart J Pocock Jacobus Lubsen Zoltán Vokó Bridget-Anne Kirwan Keith A A Fox Philip A Poole-Wilson 2006英国医学杂志中文版2006,9,1:2
4Mice lacking inducible nitric oxide synthase develop spontaneous hypercholestemlaemia and aortic atheromas显示文摘Ihrig M Dangler C A Fox J G 2001Atherosclerosis2001,156,1:1
5Calcineurin regulatory subunit is essential for virulence and mediates interactions with FKBP12-FK506 in Cryptococcus neoformans显示文摘Fox D S Cruz M C Sia R A L 2001Molecular Microbiology2001,39,:1
6High-salt diet induces Helicobacter pylori colonization in epithelial hyperplasia and parietal cell loss, and enhances helicobacter pylori colonization in C57BL/6 mice显示文摘Fox J G Dangler C A Taylor N S 1999Cancer Res1999,59,9:1
7Loss of neuro- trophin-3 from smooth muscle disrupts vagal gastrointestinal afferent signaling and satiation 显示文摘Fox E A Biddinger J E Baquet Z C 2013Am J Physiol Regul In- tegr Comp Physiol2013,305,11:1
8Performance and Properties of Mould Fluxes显示文摘Mills K C Fox A B Li Z 2005Ironmaking Steelmaking2005,32,1:1
9An apparently new transmissible disease of cattle显示文摘OLAFSON P MAC C A FOX F H 1946Cornell Vet1946,36,:1
10The adaptive significance of maternal effects 显示文摘Mousseau T A Fox C W 1998Tree1998,13,:1
11The role of central and peripheral Cannabinoid 1 receptors in the antihyperalgesic activity of cannabinoids in a model neuropathic pain显示文摘Fox A Kesingland A Gentry C 2001Pain2001,92,:1
12Differential effects of cannabinoid receptor agonists on regional brain activity using pharmacological MRI显示文摘Chin C L Tovcimak A E Hradil V P Seifert T R Hollingsworth P R Chandran P Zhu C Z Gauvin D Pai M Wetter J Hsieh G C Honore P Frost J M Dart M J Meyer M D Yao B B Cox B F Fox G B 0,,02:1
13Incremental clustering for very large document databases: Initial MARIAN experience显示文摘CAN F FOX E A SNAVELY C D 1995Information sciences1995,84,12:1
14G protein - coupled receptors in Anopheles gambiae显示文摘HILL C A FOX A N PlqqS R J 2002Science2002,298,5591:1
15Utility of plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) to distinguish between congestive heart failure and non-cardiac causes of acute dyspnea in cats显示文摘Fox P R Oyama M A Reynolds C 0,,1:1
16Prediction of ruminal volatile fatty acids and pH within thd net carbohydrate and protein system显示文摘Pitt R E Van Kessel J S Fox D G Pell A N Barry M C Van Soest P J 1996Journal of Animal Science1996,74,:1
17A novel polymerase chain reaction assay for the detection and speciation of thermophilic Campylobacter spp显示文摘Jackson C J A J Fox D M Jones 1996J Appl Bacteriol1996,81,:1
18Cerebral fat embolism and the 'starfield' pattern : a case report 显示文摘Aravapalli A Fox J Lazaridis C 2009Cases J2009,19,2:1
19The role of mould fluxes in continuous casting-so simple yet so complex 显示文摘Mills K C Fox A B 2003ISIJ International2003,43,:1
20Synthesis and Electrochemistry of a Liquid Crystalline Pyrrole and a Structurally Related Thiophene显示文摘 Nuckols C Fox M A 1994Tetrahedron Lett1994,35,45:1
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