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| 1 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 2 | Allogenic banking of dental pulp stem cells for innovative therapeutics显示文摘Medical research in regenerative medicine and cellbased therapy has brought encouraging perspectives for the use of stem cells in clinical trials. Multiple types of stem cells, from progenitors to pluripotent stem cells, have been investigated. Among these, dental pulp stem cells(DPSCs) are mesenchymal multipotent cells coming from the dental pulp, which is the soft tissue within teeth. They represent an interesting adult stem cell source because they are recovered in large amount in dental pulps with non-invasive techniques compared to other adult stem cell sources. DPSCs can be obtained from discarded teeth, especially wisdom teeth extracted for orthodontic reasons. To shift from promising preclinical results to therapeutic applications to human, DPSCs must be prepared in clinical grade lots and transformed into advanced therapy medicinal products(ATMP). As the production of patient-specific stem cells is costly and time-consuming, allogenic biobanking of clinical grade human leukocyte antigen(HLA)-typed DPSC lines provides efficient innovative therapeutic products. DPSC biobanks represent industrial and therapeutic innovations by using discarded biological tissues(dental pulps) as a source of mesenchymal stem cells to produce and store, in good manufacturing practice(GMP) conditions, DPSC therapeutic batches. In this review, we discuss about the challenges to transfer biological samples from a donor to HLA-typed DPSC therapeutic lots, following regulations, GMP guidelines and ethical principles. We also present some clinical applications, for which there is no efficient therapeutics so far, but that DPSCs-based ATMP could potentially treat. | Pierre-Yves Collart-Dutilleul Franck Chaubron John De Vos Frederic J Cuisinier | 2015 | World Journal of Stem Cells2015，7，7： | 7 |
| 3 | Chromosomal mapping of genes involved in growth control 显示文摘 | Francke U Yang - Feng T L Brissenden J E | 1986 | Cold Spring Harbor Symposia on Quantitative Biology1986，51，1： | 1 |
| 4 | Monitoring depth of anaesthesia in a randomized trial decreases the rate of postoperative delirium but not postoperative cognitive dysfunction显示文摘 | RADTKE F M FRANCK M LENDNER J | 2013 | Br J Anaesth2013，0，1： | 1 |
| 5 | Complications of Scoliosis Surgery in Prader-Willi Syndrome显示文摘 | Franck Accadbled Thierry Odent Alexandre Moine Edouard Chau Christophe Glorion Gwenaelle Diene Jér?me Sales de Gauzy | 2008 | Spine2008，，4： | 1 |
| 6 | Parent involvement in children's pain care:Views of parents and nurses显示文摘 | Simons J Franck L Roberson E | 2001 | J Adv Nurs2001，36，4： | 1 |
| 7 | Effect of very High Temperatures on the Mechanical Properties of Al-Fe-V-Si Alloy显示文摘 | Franck R E and Hawk J A | 1989 | Scripata Metal1989，23，1： | 1 |
| 8 | The Immune Microenvironment of Human Tumors: General Significance and Clinical Impact显示文摘 | Wolf-Herman Fridman Marie-Caroline Dieu-Nosjean Franck Pagès Isabelle Cremer Diane Damotte Catherine Sautès-Fridman Jér?me Galon | 2013 | Cancer Microenvironment2013，，2： | 1 |
| 9 | Complete re- sequencing and reannotation of the LactobaciUus plantarum WCFS1 genome显示文摘 | SIEZEN R J FRANCKE C RENCKENS B | 2012 | J Bacteriol2012，194，1： | 1 |
| 10 | Detecting building changes from multitemporal aerial stereopairs显示文摘 | Franck J | 2004 | Journal of Photogrammetry & Remote Sensing2004，58，： | 1 |
| 11 | Mtiller cells in the healthy and diseased retinae 显示文摘 | Bringmann A Pannicke T Grosche J Francke M Wiedemann P Skatchkov SN | 2005 | Prog Retin Eye Res2005，25，4： | 1 |
| 12 | Locate P:genome-scale subcellular-location predictor for bacterial proteins显示文摘 | Zhou M Boekhorst J Francke C | 2008 | BMC Bioinformatics2008，9，： | 1 |
| 13 | Kinetic isotope effects in the thermal cracking of neopentane显示文摘 | Franck D J Sackett W M | 1969 | Geochim Cosmochim Acta1969，33，： | 1 |
| 14 | Reevaluation of carbon-isotope composit ions of natural methanes显示文摘 | Franck D J Smith J O Sackett W M | 1974 | AAPG Bull1974，58，： | 1 |
| 15 | Effects of Copper on some Filamentous Chlorophyta显示文摘 | Francke J A Hillebrand H | 1980 | Aquatic Botany1980，8，3： | 1 |
| 16 | A New Set of Quality Indicators for Palliative Care:Process and Results of the Development Trajectory显示文摘 | CLAESSEN S J FRANCKE A L BELARBI H E | 2011 | J Pain Symptom Manage2011，42，2： | 1 |
| 17 | High pressure combustion ignition temperatures to 1000 bar显示文摘 | Steinle J U Franck E U | 1995 | Ber Bunseng- es Phys Chem1995，99，1： | 1 |
| 18 | IL-1 beta sensitizes intervertebral disc annulus cells to fluid-induced shear stress显示文摘 | ELFERVIG M K MINCHEW J T FRANCKE E | 2001 | J Cell Biochem2001，82，2： | 1 |
| 19 | A genome-wide scan for human obesity genes reveals a major susceptibility locus on chromosome 10显示文摘 | Hager J Dina C Francke S | | 0，，3： | 1 |
| 20 | Experimental retinal detachment causes widespread and multilayered degeneration in rabbit retina 显示文摘 | Faude F Francke M Makarov F Schuck J Gartner U Reichelt W | 2001 | J Neurocy- tol2001，30，5： | 1 |
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