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| 1 | Optical coherence tomography characteristics of responses to intravitreal bevacizumab in idiopathic choroidal neovascularization显示文摘AIM: To investigate factors associated with responses to intravitreal bevacizumab(IVB) in naive idiopathic choroidal neovascularization(i CNV) by high domain optical coherence tomography(OCT).·METHODS: We retrospectively reviewed clinical data of40 eyes of i CNV patients who received a single or multiple IVB on an as-needed basis(1.25 mg/0.05 m L).One month after the first injection, subretinal fluid(SRF)volume was evaluated and the eyes were divided into 3groups based on responses to IVB. Good, moderate, and poor responses were defined as 61%-99%, 30%-60%,and <30% resolution of SRF on OCT after IVB in i CNV,respectively. OCT findings were analyzed to find factors associated with difference in response levels.Comparisons were made using Wilcoxon's matched-pairs signed-rank test, the Mann-Whitney U test for means with continuous data and Fisher's exact test for categorical data.·RESULTS: The mean number of IVB was 1.28±1.50 and mean follow up time was 3.60 ±1.20 mo. At postoperative1 mo, there were 8(20%) eyes in good response, 20(50%)in moderate response and 12(30%) eyes in poor response group and at last visit there were 28 good responders(70%), 8(20%) moderate responders and 4(10%) poor responders. Statistically significant difference was detected between good responders and non good responders in choroidal neovessels thickness(P =0.029),SRF height(P =0.049) and SRF volume(P =0.031) at post treatment 1mo.· CONCLUSION: OCT is a valuable diagnostic tool.Decrease in choroidal neovessels thickness, SRF height and volume predicts favorable response of i CNV to IVB therapy. | Syed Nasir Ali Shah Qian-Yan Kang Xiao-Juan Fan Yue-Ming Sun | 2016 | International Journal of Ophthalmology(English edition)2016，9，2： | 2 |
| 2 | Effects of activation of Caspase-3in cerebral ischemic reperfusion injury显示文摘 | Yang Y Zhang SM Fan SY | 2004 | Zhonghua Yi Xue Za Zhi2004，84，： | 1 |
| 3 | Synthesis and evaluation of novel chloropyridazine derivatives as potent human rhinovirus (HRV) capsid-binding inhibitors 显示文摘 | Fan SY Zheng ZB Mi CL | 2009 | Bioorg Med Chem2009，17，： | 1 |
| 4 | Health-related quality of life in patientswith hepatocellular carcinoma:a systematic review显示文摘 | Fan SY Eiser C Ho MC | 2010 | Clin Gast-roenterol Hepatol2010，8，7： | 1 |
| 5 | Multidetector CT features of Pulmonary focal ground-glass oPacity: differences between benign and malignant显示文摘 | Fan L Liu SY Li QC | 2012 | Br J Radiol2012，85，： | 1 |
| 6 | Discovery of xanthine oxidase inhibitors and/or α - glucosidase inhibitors by carboxyalkyl derivatization based on the flavonoid of apigenin显示文摘 | Su ZR Fan SY Shi WG | 2015 | Bioorg Med Chem Lett2015，25，14： | 1 |
| 7 | Treatment with angiotensin-(1-9)alleviates the cardiomyopathy in streptozotocin-induced diabetic rats显示文摘 | ZHENG H PU SY FAN XF | 2015 | Biochem Pharmacol2015，95，1： | 1 |
| 8 | Estrogen receptor alpha induces prosurvival autophagy in papillary thyroid cancer via stimulating reactive oxygen species and extracellular signal regulated kinases显示文摘 | Fan D Liu SY van Hasselt CA | | J Clin Endocrinol Metab0，100，4： | 1 |
| 9 | Hypoxia-ischemia induced neurological dysfunction and brain injury in the neonatal rat显示文摘 | Fan LW Lin SY Pang Y | 2005 | Behav Brain Res2005，165，1： | 1 |
| 10 | Health-related quality of life in patients with mediation effects of illness perceptions and coping显示文摘 | Fan SY Eiser C Ho MC | 2013 | Psychooncology2013，3，22： | 1 |
| 11 | Enabled/disabled predicate encryption in clouds 显示文摘 | SY Huang CI Fan YF Tseng | 2016 | Future Generation Computer Sys- tems2016，2，1： | 1 |
| 12 | Multidetector CT features of pulmonary focal ground-glass opacity:differences between benign and malignant显示文摘 | Fan L Liu SY Li QC | 2012 | Br J Radiol2012，85，115： | 1 |
| 13 | Randomized controlled trial of heart rate variability biofeedback in cardiac autonomic and hostility among patients with coronary artery disease显示文摘 | Lin IM Fan SY Lu HC | 2015 | Behav Res Ther2015，70，： | 1 |
| 14 | The glucose oxidase - DAB - nickel method in peroxidase histochemistry of the nervous system 显示文摘 | Shu SY Ju G and Fan JZ | 1988 | Neurosci Let1988，85，2： | 1 |
| 15 | Role of the Tumor Microenvironment in Mediating Response to Anti-angiogenic Therapy显示文摘 | Young D. Jung Syed A. Ahmad Yoshito Akagi Yutaka Takahashi Wenbiao Liu Niels Reinmuth Raymond M. Shaheen Fan Fan Lee M. Ellis | 2000 | Cancer and Metastasis Reviews (-)2000，，1： | 1 |
| 16 | Muhidetector CT features of pulmona- ry focal ground-glass opacity: differences between benign and malig- nant显示文摘 | Fan L Liu SY Li QC | 2012 | Br J Radio12012，85，1015： | 1 |
| 17 | Cholangiocarcinomas can originate from hepatocytes in mice显示文摘 | Fan Biao Malato Yann Calvisi Diego F Naqvi Syed Razumilava Nataliya Ribback Silvia Gores Gregory J Dombrowski Frank Evert Matthias Chen Xin Willenbring Holger | 2012 | EN2012，，8： | 1 |
| 18 | Demonstration of pulmonary perfusion heterogeneity induced by gravity and lung inflation using arterial spin labeling显示文摘 | Fan L Liu SY Xiao XS | 2010 | Eur J Radiol2010，73，2： | 1 |
| 19 | Assessment of pulmonary parenchyma perfusion with FAIR in comparison with DCE-MRI-initial results 显示文摘 | Fan L Liu SY Sun F | 2009 | EurJ Radiol2009，70，： | 1 |
| 20 | CCNDI and ERBB2-gene deregulation and PTEN mutationanalyses in invasive lobular carcinoma of the breast显示文摘 | Mercapide J Zhang SY Fan X | 2002 | Mol Carcinog2002，35，1： | 1 |
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