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8篇 您的检索式:作者名="Fan Shufen"
    题名 作者 年代 出处 被引量
1Three lignocellulose features that distinctively affect biomass enzymatic digestibility under NaOH and H 2 SO 4 pretreatments in Miscanthus显示文摘Wei Zhang Zili Yi Jiangfeng Huang Fengcheng Li Bo Hao Ming Li Shufen Hong Yezi Lv Wei Sun Arthur Ragauskas Fan Hu Junhua Peng Liangcai Peng 2012Bioresource Technology2012,,:1
2Cooperative enhancement of capacities in nanostructured Sn/Sb/ carbon nanotube network nanocomposite as anode for lithium ion batteries显示文摘Fan Shufen Sun Ting Ruo Xianhong 2012Journal of Power Sources2012,201,:1
3A quantitative analysis of oleanolic acid in six Zangyinchen drugs from Qinghai Province显示文摘SUN Hongfa FAN Shufen DING Jingye 1987Acta Biological Plateau Sinica1987,,6:1
4Phase control of gain and dispersion in an openV-type system显示文摘Fan Xijun Li Jingjuan Tian Shufen Cui Ni Li Hua Li Aiyun Xu Zhizhan 2005J Modern Opt2005,52,12:1
5A nonlinear analytical and numerical study for an open system with coherent off-resonant fields 显示文摘Fan Xijun Li Ping Tian Shufen 2001Chinese Phys2001,50,7:1
6Blue top-emitting organic light-emitting devices based on wide-angle interference enhancement and suppression of multiple-beam interference显示文摘Jun Xie Chunyan Chen Shufen Chen Yang Yang Ming Shao Xu Guo Quli Fan Wei Huang 2010Organic Electronics2010,,2:1
7Multifunctional shape-dependent plasmonic nanoprobe by enzymatic etching of single gold triangular nanoplate显示文摘Hydrogen peroxide(H2O2),as a signaling molecule,plays a vital role in a wide variety of signaling transduction processes,aging,and diseases.However,the excessive production of H2O2 causes various diseases.Herein,we develop a novel method for H2O2 detection in live cells via dark-field scattering spectroscopy with gold triangular nanoprisms(AuTNPs)as probes.The corners of AuTNPs would be gradually oxidatively etched by the strong coordination of Br•which is generated by enzymatic reactions in the presence of horseradish peroxidase(HRP),bromide ion and trace hydrogen peroxide.Benefitting from the morphological change,the single AuTNP based plasmonic nanoprobe shows notable blueshifts and scattering color changes which could be real-time monitored under the dark-field microscopy.The peak position in the scattering spectra of individual AuTNP blueshifts linearly with the increase of H2O2 concentration,and exhibits high sensitivity to H2O2 in a large range from 2.5 to 100µM with a low detection limit(LOD)of 0.74µM.Moreover,the experimental results were supported by the simulated results via the finite-difference time-domain(FDTD)method.The nanoprobes have been further used for intracellular H2O2 detection in live cells.Besides,the etching of AuTNP also provides an alternative method to design novel plasmonic logic chips and write-once plasmonic memories.Ning Feng Jingjing Shen Yu Chen Chang Li Yanling Hu Lei Zhang Shufen Chen Quli Fan Wei Huang Lianhui Wang 2020Nano Research2020,13,12:0
8SARS-CoV-2 Z-RNA activates the ZBP1-RIPK3 pathway to promote virus-induced inflammatory responses显示文摘SARS-CoV-2 infection can trigger strong inflammatory responses and cause severe lung damage in COVID-19 patients with critical illness.However,the molecular mechanisms by which the infection induces excessive inflammatory responses are not fully understood.Here,we report that SARS-CoV-2 infection results in the formation of viral Z-RNA in the cytoplasm of infected cells and thereby activates the ZBP1-RIPK3 pathway.Pharmacological inhibition of RIPK3 by GSK872 or genetic deletion of MLKL reduced SARS-CoV-2-induced IL-1βrelease.ZBP1 or RIPK3 deficiency leads to reduced production of both inflammatory cytokines and chemokines during SARS-CoV-2 infection both in vitro and in vivo.Furthermore,deletion of ZBP1 or RIPK3 alleviated SARS-CoV-2 infection-induced immune cell infiltration and lung damage in infected mouse models.These results suggest that the ZBP1-RIPK3 pathway plays a critical role in SARS-CoV-2-induced inflammatory responses and lung damage.Our study provides novel insights into how SARS-CoV-2 infection triggers inflammatory responses and lung pathology,and implicates the therapeutic potential of targeting ZBP1-RIPK3 axis in treating COVID-19.Shufen Li Yulan Zhang Zhenqiong Guan Meidi Ye Huiling Li Miaomiao You Zhenxing Zhou Chongtao Zhang Fan Zhang Ben Lu Peng Zhou Ke Peng 2023Cell Research2023,33,3:0
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