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| 1 | Thick ceramic thermal barrier coatings with high durability deposited using solution-precursor plasma spray显示文摘 | Amol Jadhav Nitin P. Padture Fang Wu Eric H. Jordan Maurice Gell | 2005 | Materials Science & Engineering A2005,,1: | 2 |
| 2 | Effect of closure of live poultry markets on poultry-to-person transmission of avian influenza A H7N9 virus: an ecological study显示文摘 | Hongjie Yu Joseph T Wu Benjamin J Cowling Qiaohong Liao Vicky J Fang Sheng Zhou Peng Wu Hang Zhou Eric H Y Lau Danhuai Guo Michael Y Ni Zhibin Peng Luzhao Feng Hui Jiang Huiming Luo Qun Li Zijian Feng Yu Wang Weizhong Yang Gabriel M Leung | 2013 | The Lancet2013,,: | 2 |
| 3 | The effect of export marketing capabilities on export performance: An investigation of Chinese exporters 显示文摘 | Zou Shaoming Fang Eric Zhao Shuming | 2003 | Journal of International Marketing2003,11,4: | 1 |
| 4 | Effect of humic acid and metal ions on the debromination of BDE209 by nZVM prepared from steel pickling waste liquor显示文摘作为一在 situ 补习技术答应, nanoscale zero-valent 铁(nZVI ) 能有效地移开象 decabromodiphenyl 醚(BDE209 ) 那样的 polybrominated diphenyl 醚,然而,它的使用被它的高生产费用限制。用是的钢 pickling 浪费白酒,准备 nanoscale zero-valent 金属(nZVM ) 的原料能克服这缺乏。腐殖的酸和金属离子在补习上有最大的影响,这被显示出。结果证明 nZVM 和 nZVI 能有效地两个都在他们的移动效率与小差别移开 BDE209,并且腐殖的酸禁止了移动效率,而金属离子支持了它。支持的效果跟随了顺序 Ni 2+> Cu 2+> 公司 2+ 和二个因素的累积效果是支持和禁止的单个效果的联合。当 nZVM 的是水晶时, nZVM 和 nZVI 之间的主要差别躺在他们的水晶形式,当 nZVI 被发现非结晶。然而, nZVM 和 nZVI 与类似的移动效率移开 BDE209,这被发现。效果和 nZVM 和 nZVI 上的腐殖的酸和金属离子的累积效果以 BDE209 移动的效率是很类似的。 | Yuling CAI | 2015 | Frontiers of Environmental Science & Engineering2015,9,5: | 1 |
| 5 | Comparative epidemiology of human infections with avian influenza A H7N9 and H5N1 viruses in China: a population-based study of laboratory-confirmed cases显示文摘 | Benjamin J Cowling Lianmei Jin Eric HY Lau Qiaohong Liao Peng Wu Hui Jiang Tim K Tsang Jiandong Zheng Vicky J Fang Zhaorui Chang Michael Y Ni Qian Zhang Dennis KM Ip Jianxing Yu Yu Li Liping Wang Wenxiao Tu Ling Meng Joseph T Wu Huiming Luo Qun Li Yuelong | 2013 | The Lancet2013,,9887: | 1 |
| 6 | A 10-kDa Structural Protein of Porcine Reproductive and Respiratory Syndrome Virus Encoded by ORF2b显示文摘 | Wai-Hong Wu Ying Fang Rachel Farwell Melissa Steffen-Bien Raymond R.R Rowland Jane Christopher-Hennings Eric A Nelson | 2001 | Virology2001,,1: | 1 |
| 7 | Host response after reconstruction of abdominal wall defects with porcine dermal collagen in a rat model 显示文摘 | Fang Zheng Yuan Lin Eric Verbeken | 2004 | American Journal of Obstetrics and Gynecology2004,191,: | 1 |
| 8 | Heterogeneity in Nsp2 of European-like porcine reproductive and respiratory syndrome viruses isolated in the United States显示文摘 | Ying Fang Dal-Young Kim Susan Ropp Pam Steen Jane Christopher-Hennings Eric A. Nelson Raymond R.R. Rowland | 2004 | Virus Research2004,,2: | 1 |
| 9 | CRISPR/Cas9 screening identifies a kinetochore-microtubule dependent mechanism for Aurora-A inhibitor resistance in breast cancer显示文摘Background:Overexpression of Aurora-A(AURKA)is a feature of breast cancer and associates with adverse prognosis.The selective Aurora-A inhibitor alisertib(MLN8237)has recently demonstrated promising antitumor responses as a single agent in various cancer types but its phase III clinical trial was reported as a failure since MLN8237 did not show an apparent effect in prolonging the survival of patients.Thus,identification of potential targets that could enhance the activity of MLN8237 would provide a rationale for drug combination to achieve better therapeutic outcome.Methods:Here,we conducted a systematic synthetic lethality CRISPR/Cas9 screening of 507 kinases using MLN8237 in breast cancer cells and identified a number of targetable kinases that displayed synthetic lethality interactions with MLN8237.Then,we performed competitive growth assays,colony formation assays,cell viability assays,apoptosis assays,and xenograft murine model to evaluate the synergistic therapeutic effects of Haspin(GSG2)depletion or inhibition with MLN8237.For mechanistic studies,immunofluorescence was used to detect the state of microtubules and the localization of Aurora-B and mitotic centromere-associated kinesin(MCAK).Results:Among the hits,we observed that Haspin depletion or inhibition marginally inhibited breast cancer cell growth but could substantially enhance the killing effects of MLN8237.Mechanistic studies showed that co-treatment with Aurora-A and Haspin inhibitors abolished the recruitment of Aurora-B and mitotic centromere-associated kinesin(MCAK)to centromeres which were associated with excessive microtubule depolymerization,kinetochore-microtubule(KT-MT)attachment failure,and severe mitotic catastrophe.We further showed that the combination of MLN8237 and the Haspin inhibitor CHR-6494 synergistically reduced breast cancer cell viability and significantly inhibited both in vitro and in vivo tumor growth.Conclusions:These findings establish Haspin as a synthetic lethal target and demonstrate CHR-6494 as a potential combinational drug for promoting the therapeutic effects of MLN8237 on breast cancer. | Ailin Chen Shijun Wen Fang Liu Zijian Zhang Meiling Liu Yuanzhong Wu Bin He Min Yan Tiebang Kang Eric W-F Lam Zifeng Wang Quentin Liu | 2021 | Cancer Communications2021,41,2: | 1 |
| 10 | Customer Participation and the Trade-Off Between New Product Innovativeness and Speed to Market 显示文摘 | Eric (Er) Fang | 2008 | Journal of Marketing2008,72,7: | 1 |
| 11 | Comparative epidemiology of human infections with avian influenza A H7N9 and H5N1 viruses in China: a population-based study of laboratory-confirmed cases显示文摘 | Benjamin J Cowling Lianmei Jin Eric HY Lau Qiaohong Liao Peng Wu Hui Jiang Tim K Tsang Jiandong Zheng Vicky J Fang Zhaorui Chang Michael Y Ni Qian Zhang Dennis KM Ip Jianxing Yu Yu Li Liping Wang Wenxiao Tu Ling Meng Joseph T Wu Huiming Luo Qun Li Yuelong | 2013 | The Lancet . 2013 (9887)2013,,9887: | 1 |
| 12 | Customer Participation and Trade-Off Between New Product Innovativeness and Speed to Market显示文摘 | Fang Eric | 2008 | Journal of Marketing2008,72,4: | 1 |
| 13 | Antecedents and Consequences of Marketing Dynamic Capabilities in International Joint Ventures显示文摘 | Fang Eric (Er) Zou Shaoming | 2009 | Journal of International Business Studies2009,,40: | 1 |
| 14 | Sales Channel Integration after Mergers and Acquisitions: A Methodological Approach for Avoiding Common Pitfalls 显示文摘 | Robert W Palmatier C Fred Miao Eric Fang | 2007 | Industrial Marketing Management2007,36,5: | 1 |
| 15 | Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe显示文摘 | Michel Warny Jacques Pepin Aiqi Fang George Killgore Angela Thompson Jon Brazier Eric Frost L Clifford McDonald | 2005 | The Lancet2005,,9491: | 1 |
| 16 | Real-Time PCR Microfluidic Devices with Concurrent Electrochemical Detection显示文摘 | Teh Huey Fang Naveen Ramalingam Dong Xian-Dui Tan Swee Ngin Zeng Xianting Annie Tan Lai Kuan Eric Yap Peng Huat Gong Hai-Qing | 2009 | Biosensors and Bioelectronics2009,24,7: | 1 |
| 17 | Characterization of the gene expression profile of human bocavirus显示文摘 | Aaron Yun Chen Fang Cheng Sai Lou Yong Luo Zhengwen Liu Eric Delwart David Pintel Jianming Qiu | 2010 | Virology2010,,2: | 1 |
| 18 | Dissection of TBK1 signaling via phosphoproteomics in lung cancer cells显示文摘 | Jae-Young Kim Eric A. Welsh Umut Oguz Bin Fang Yun Bai Fumi Kinose Crystina Bronk Lily L. Remsing Rix Amer A. Beg Uwe Rix Steven A. Eschrich John M. Koomen Eric B. Haura | 2013 | Proceedings of the National Academy of Sciences2013,,30: | 1 |
| 19 | 中国强迫症患者愤怒发作的发生率及其临床相关因素(英文)显示文摘目的:强迫症患者的愤怒发作通常由强迫症状触发。然而,中国强迫症患者愤怒发作临床特征的相关研究报道较少。本研究主要探讨中国强迫症患者愤怒发作的发生率及其临床相关因素。创新点:本研究是第一篇探讨中国强迫症患者愤怒发作的临床特点的研究。研究发现:教育水平越高的强迫症患者愤怒发作的严重程度越低。方法:九十例15~78岁的原发性强迫症患者参与了本研究。研究人员对患者进行了以下量表的评估:愤怒发作和愤怒严重程度量表(ROARS)、耶鲁-布朗强迫量表第二版(Y-BOCS-Ⅱ)和布朗信念评估量表(BABS)。强迫症患者完成了改良强迫问卷-修订版(OCI-R)和抑郁焦虑应激量表(DASS-12)。结论:31.3%的强迫症患者在过去一周内有愤怒发作,ROARS的得分与年龄、疾病病程、强迫症严重程度、抑郁和压力没有显著相关性。ROARS得分与教育程度呈负相关,与强迫思维和焦虑程度呈正相关。 | Ying-ying ZHANG Heng-fen GONG Xiao-li ZHANG Wen-juan LIU Hai-yan JIN Fang FANG Sophie SCHNEIDER Elizabeth MCINGVALE Chen-cheng ZHANG Wayne K.GOODMAN Xi-rong SUN Eric A.STORCH | 2019 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2019,20,4: | 1 |
| 20 | The effects of customer acquisition and retention orientations on a firm' s radical and incremental innovation performance显示文摘 | Todd J.Arnold Eric (Er) Fang Robert W.Palmatier | | 0,,: | 1 |