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| 1 | Comprehensive strategy of conduit guidance combined with VEGF producing Schwann cells accelerates peripheral nerve repair显示文摘Peripheral nerve regeneration requires stepwise and well-organized establishment of microenvironment.Since local delivery of VEGF-A in peripheral nerve repair is expected to promote angiogenesis in the microenvironment and Schwann cells(SCs)play critical role in nerve repair,combination of VEGF and Schwann cells may lead to efficient peripheral nerve regeneration.VEGF-A overexpressing Schwann cells were established and loaded into the inner wall of hydroxyethyl cellulose/soy protein isolate/polyaniline sponge(HSPS)conduits.When HSPS is mechanically distorted,it still has high durability of strain strength,thus,can accommodate unexpected strain of nerve tissues in motion.A 10 mm nerve defect rat model was used to test the repair performance of the HSPS-SC(VEGF)conduits,meanwhile the HSPS,HSPS-SC,HSPS-VEGF conduits and autografts were worked as controls.The immunofluorescent co-staining of GFP/VEGF-A,Ki67 and MBP showed that the VEGF-A overexpressing Schwann cells could promote the proliferation,migration and differentiation of Schwann cells as the VEGF-A was secreted from the VEGF-A overexpressing Schwann cells.The nerve repair performance of the multifunctional and flexible conduits was examined though rat behavioristics,electrophysiology,nerve innervation to gastrocnemius muscle(GM),toluidine blue(TB)staining,transmission electron microscopy(TEM)and NF200/S100 double staining in the regenerated nerve.The results displayed that the effects on the repair of peripheral nerves in HSPS-SC(VEGF)group was the best among the conduits groups and closed to autografts.HSPS-SC(VEGF)group exhibited notably increased CD31+endothelial cells and activation of VEGFR2/ERK signaling pathway in the regenerated nerve tissues,which probably contributed to the improved nerve regeneration.Altogether,the comprehensive strategy including VEGF overexpressing Schwann cells-mediated and HSPS conduit-guided peripheral nerve repair provides a new avenue for nerve tissue engineering. | Ping Wu Zan Tong Lihua Luo Yanan Zhao Feixiang Chen Yinping Li Céline Huselstein Qifa Ye Qingsong Ye Yun Chen | 2021 | Bioactive Materials2021，6，10： | 4 |
| 2 | Large Scale One-Pot Synthesis of Monodispersed Na_(3)(VOPO_(4))_(2)F Cathode for Na-Ion Batteries显示文摘Na-ion batteries(NIBs)have received significant interest as potential candidates for large-scale energy storage owing to the widespread distribution of sodium and superior low-temperature performance.However,their commercial application is usually hindered by the high production cost and inadequate performance for electrode materials,particularly for cathodes.Na_(3)(VOPO_(4))_(2)F(NVOPF)has been recognized as one of the most promising cathodes for high-energy NIBs owing to the high working voltage and energy density.Here,we report a facile highly efficient room-temperature solution protocol for large-scale synthesis of NVOPF cathode for NIBs.By simply regulating pH,NVOPF can be obtained,which delivered a discharge capacity of 120.2 mAh g^(-1) at 0.1 C and 72%capacity retention over 8000 cycles at 25 C.Besides,the kilogram-level NVOPF products have been synthesized,and 26650 cylindrical cells were fabricated,which exhibit excellent cycling stabilities,remarkable lowtemperature performance with comparable safety features.We hope our findings could provide insights on the industrial application of NVOPF in NIBs. | Qiangqiang Zhang Xing Shen Quan Zhou Kaixuan Li Feixiang Ding Yaxiang Lu Junmei Zhao Liquan Chen Yong-Sheng Hu | 2022 | Energy Material Advances2022，，1： | 2 |
| 3 | Provably secure attribute-based authenticated encryption with keyword search from ideal lattices显示文摘A public-key authenticated encryption with keyword search(PAEKS)[1,2]system overcomes the problem of an inside adversary forging searchable ciphertexts and guessing the keyword information from the given token.This system allows the sender to encrypt and authenticate a keyword.However,traditional PAEKS schemes require the sender to specify the intended receiver in advance,losing much flexibility. | Lisha YAO Lin HOU Jian WENG Feixiang ZHAO | 2024 | Science China(Information Sciences)2024，67，1： | 1 |
| 4 | Pilot study on jetting pre-oxidation fluidized bed gasification adapting to caking coal显示文摘 | Zhang Juwei Zhao Zhigang Zhang Guangyi Zeng Xi Zhao Feixiang Dong Li Xu Guangwen | | 0，，： | 1 |
| 5 | Boosting reversible anionic redox reaction with Li/Cu dual honeycomb centers显示文摘The anionic redox reaction(ARR)is a promising charge contributor to improve the reversible capacity of layeredoxide cathodes for Na-ion batteries;however,some practical bottlenecks still need to be eliminated,including a low capacity retention,large voltage hysteresis,and low rate capability.Herein,we proposed a high-Na content honeycomb-ordered cathode,P2–Na_(5/6)[Li_(1/6)Cu_(1/6)Mn_(2/3)]O_(2)(P2-NLCMO),with combined cationic/anionic redox.Neutron powder diffraction and X-ray diffraction of P2-NLCMO suggested P2-type stacking with rarely found P6322 symmetry.In addition,advanced spectroscopy techniques and density functional theory calculations confirmed the synergistic stabilizing relationship between the Li/Cu dual honeycomb centers,achieving fully active Cu^(3+)/Cu^(2+) redox and stabilized ARR with interactively suppressed local distortion.With a meticulously regulated charge/discharge protocol,both the cycling and rate capability of P2-NLCMO were significantly. | Xiaohui Rong Dongdong Xiao Qinghao Li Yaoshen Niu Feixiang Ding Xueyan Hou Qiyu Wang Juping Xu Chenglong Zhao Dong Zhou Ruijuan Xiao Xiqian Yu Wen Yin Lin Gu Hong Li Xuejie Huang Liquan Chen Yong-Sheng Hu | 2023 | eScience2023，3，5： | 0 |
| 6 | Lattice-based autonomous path proxy re-encryption in the standard model显示文摘Autonomous path proxy re-encryption(AP-PRE)is a type of PRE that implements control on the delegation path in a multi-hop PRE.AP-PRE forces the proxy to perform the transformation along a predefined path without revealing the underlying plaintext.There are several applications of AP-PRE,including electronic medical systems,data sharing,and email systems.However,as far as we know,the existing AP-PRE scheme is provably secure in the random oracle model under the classical number-theoretic assumption,which might be vulnerable to quantum computers.Therefore,it raises the intriguing question of how to construct a quantum-resistant AP-PRE scheme.In this study,we proposed an AP-PRE scheme based on the widely accepted quantum-resistant learning with errors(LWE)assumptions.Our scheme supports the polynomial length of the delegation path.Furthermore,our scheme is proved to be selective-path CPA(sCPA)secure in the standard model under LWE assumptions. | Wenli XIE Jian WENG Yao TONG Xiaojian LIANG Lisha YAO Feixiang ZHAO | 2023 | Science China(Information Sciences)2023，66，10： | 0 |
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