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| 1 | Zircon U-Pb dating on the Mesozoic volcanic suite from the Qingshan Group stratotype section in eastern Shandong Province and its tectonic significance显示文摘A geochronological study of zircon U-Pb on the volcanic rocks from the stratotype section of the Qingshan Group within the Jiaozhou Basin, eastern Shandong Province, is presented. The zircons were analyzed using the method of in situ ablation of a 193 nm excimer laser system coupled with an up to date ICP-MS system. Among the three formations of the Qingshan Group, zircons recovered from the lowest part of the Houkuang Fm. were dated at 106±2 Ma (95% confidence, the same below), whereas those from the lower and upper parts of the Shiqianzhuang Fm. were given ages of 105±4 Ma and 98±1 Ma, respectively. A spatially decreasing trend for the Mesozoic magmatic timing from west to east in the province is observed through comparing the data of this study with those by previous works on the Qingshan volcanic lavas occurring at western Shandong and within the Yishu fault zone. The Qingshan volcanic rocks are constituent of the 'Shoshonite Province' in East China. Exposed at most provinces of central East China along the Tan-Lu fault and the Yangtze fault zones, these volcanic suites are characterized by shoshonite and high-K calcalkalic rocks in lithology and thought to be correlated with the partial melting of continental mantle in genesis. It is also shown that the Qingshan potassic volcanic suite from eastern Shandong basins is distinctly younger than those from other ar-eas of the shoshonite province. By contrary, ages of the Mesozoic to Cenozoic alkaline basalts, sourced by asthenospheric mantle, from both northern Huaiyan basin and northern Dabie belt along the Tan-Lu fault zone and from the Ningwu, Lishui and Luzong basins along the Yangtze fault zone are observably older than those occurring within eastern Shandong. The revealed temporal and spatial patterns in magmatism for the two types of volcanic suites make an important geochronological con-straint on the Mesozoic to Cenozoic dynamic evolution model of the subcontinental lithosphere in East China. | LING WenLi XIE XianJun LIU XiaoMing CHENG JianPing | 2007 | Science China Earth Sciences2007，50，6： | 18 |
| 2 | GYY4137 protects against myocardial ischemia and reperfusion injury by attenuating oxidative stress and apoptosis in rats显示文摘Hydrogen sulfide(H_2S) is a gasotransmitter that regulates cardiovascular functions.The present study aimed to determine the protective effect of slow-releasing H_2S donor GYY4137 on myocardial ischemia and reperfusion(I/R) injury and to investigate the possible signaling mechanisms involved.Male Sprague-Dawley rats were treated with GYY4137 at 12.5 mg/(kg·day),25 mg/(kg·day) or 50 mg/(kg·day) intraperitoneally for7 days.Then,rats were subjected to 30 minutes of left anterior descending coronary artery occlusion followed by reperfusion for 24 hours.We found that GYY4137 increased the cardiac ejection fraction and fractional shortening,reduced the ischemia area,alleviated histological injury and decreased plasma creatine kinase after myocardial I/R.Both H_2S concentration in plasma and cystathionine-γ-lyase(CSE) activity in the myocardium were enhanced in the GYY4137 treated groups.GYY4137 also decreased malondialdehyde and myeloperoxidase levels in serum,attenuated superoxide anion level and suppressed phosphorylation of mitogen activated protein kinases in the myocardium after I/R.Meanwhile,GYY4137 increased the expression of Bcl-2 but decreased the expression of Bax,caspase-3 activity and apoptosis in the myocardium.The data suggest that GYY4137 protects against myocardial ischemia and reperfusion injury by attenuating oxidative stress and apoptosis. | Guoliang Meng Jing Wang Yujiao Xiao Wenli Bai Liping Xie Liyang Shan Philip K Moore Yong Ji | 2015 | The Journal of Biomedical Research2015，29，3： | 18 |
| 3 | A microporous surface containing Si3N4/Ta microparticles of PEKK exhibits both antibacterial and osteogenic activity for inducing cellular response and improving osseointegration显示文摘As an implantable biomaterial,polyetherketoneketone(PEKK)exhibits good mechanical strength but it is biologically inert while tantalum(Ta)possesses outstanding osteogenic bioactivity but has a high density and elastic modulus.Also,silicon nitride(SN)has osteogenic and antibacterial activity.In this study,a microporous surface containing both SN and Ta microparticles on PEKK(STP)exhibiting excellent osteogenic and antibacterial activity was created by sulfonation.Compared with sulfonated PEKK(SPK)without microparticles,the surface properties(roughness,surface energy,hydrophilicity and protein adsorption)of STP significantly increased due to the SN and Ta particles presence on the microporous surface.In addition,STP also exhibited outstanding antibacterial activity,which inhibited bacterial growth in vitro and prevented bacterial infection in vivo because of the presence of SN particles.Moreover,the microporous surface of STP containing both SN and Ta particles remarkably induced response(e.g.,proliferation and differentiation)of rat bone mesenchymal stem(rBMS)cells in vitro.Furthermore,STP significantly improved new bone regeneration and osseointegration in vivo.Regarding the induction of cellular response in vitro and improvement of osseointegration in vivo,the microporous surface containing Ta was better than the surface with SN particles.In conclusion,STP with optimized surface properties activated cellular responses in vitro,enhanced osseointegration and prevented infection in vivo.Therefore,STP possessed the dual biofunctions of excellent osteogenic and antibacterial activity,showing great potential as a bone substitute. | Xinglong Hu Shiqi Mei Fan Wang Songchao Tang Dong Xie Chao Ding Wenli Du Jun Zhao Lili Yang Zhaoying Wu Jie Wei | 2021 | Bioactive Materials2021，6，10： | 6 |
| 4 | The Effect of Home-Based Cardiac Rehabilitation on Functional Capacity,Behavior,and Risk Factors in Patients with Acute Coronary Syndrome in China显示文摘Aim:To investigate the effect of home-based cardiac rehabilitation on functional capacity,health behavior,and risk factors in patients with acute coronary syndrome in China.Methods:Eighty patients with acute coronary syndrome were enrolled in this prospective randomized controlled study.Patients in the cardiac rehabilitation group(n=52)received home-based cardiac rehabilitation with a heart manual and a home exercise video for 3 months and patients in the control group(n=28)received only routine secondary prevention.The 6-min walk distance,laboratory test results,healthy behavior(questionnaire),quality of life(12-item Short Form Health Survey),anxiety(7-item Generalized Anxiety Disorder Questionnaire),and depression(9-item Patient Health Questionnaire)were evaluated at the beginning and after treatment for 3 months.Results:Compared with baseline data,52 patients who participated in cardiac rehabilitation had longer 6-min walk distance(515.26±113.74 m vs 0.445.30±97.92 m,P<0.0002),higher proportions of“always exercise”(78.26% vs.28%,P<0.05),“always limit food with sugar”(65.22% vs 12%,P<0.05),“always eat fruits 200–400 g every day”(82.61% vs.4%,P<0.05).and“always eat vegetables 300–500 g every day”(21.74%vs.12%,P<0.06)after treatment for 3 months.The low-density lipoprotein cholesterol control rate(52.17% vs.28%,P<0.05)and the systolic blood pressure control rate(100%vs.68%,P<0.05)were also signifi cantly increased after treatment for 3 months in the cardiac rehabilitation group.No signifi cant increase was found in the control group after treatment for 3 months.No cardiac-event related to home exercise was reported in both groups.Conclusion:Home-based cardiac rehabilitation is a feasible and available cardiac rehabilitation mode in China. | Rongjing Ding Jianchao Li Limin Gao Liang Zhu Wenli Xie Xiaorong Wang Qin Tang Huili Wang Dayi Hu | 2017 | Cardiovascular Innovations and Applications2017，，B02： | 5 |
| 5 | Improving water use ef fi ciency in grain production of winter wheat and summer maize in the North China Plain: a review显示文摘Reducing irrigation water use by improving water use ef ficiency(WUE) in grain production is critical for the development of sustainable agriculture in the North China Plain(NCP). This article summarizes the research progresses in WUE improvement carried out at the Luancheng station located in the Northern part of NCP for the past three decades. Progresses in four aspects of yield and WUE improvement are presented, including yield and WUE improvement associated with cultivar selection, irrigation management for improving yield and WUE under limited water supply, managing root system for ef ficient soil water use and reducing soil evaporation by straw mulch. The results showed that annual average increase of 0.014 kg$m^(–3)for winter wheat and 0.02 kg$m^(–3)in WUE were observed for the past three decades, and this increase was largely associated with the improvement in harvest index related to cultivar renewal and an increase in chemical fertilizer use and soil fertility. The results also indicated that de ficit irrigation for winter wheat could signi ficantly reduce the irrigation water use, whereas the seasonal yield showed a smaller reduction rate and WUE was signi ficantly improved. Straw mulching of summer maize using the straw from winter wheat could reduce seasonal soil evaporation by 30–40 mm. With new cultivars and improved management practices it was possible to further increase grain production without much increase in water use. Future strategies to further improve WUE are also discussed. | Xiying ZHANG Wenli QIN Juanna XIE | 2016 | Frontiers of Agricultural Science and Engineering2016，3，1： | 4 |
| 6 | ZrO2 nanoparticles anchored on nitrogen-doped carbon nanosheets as efficient catalyst for electrochemical CO2 reduction显示文摘Electrochemical reduction of CO2 to produce value-added feedstock chemicals using high-performance electrocatalysts is a promising protocol to address the excessive CO2 in the atmosphere and the energy crisis. However, the high overpotential, low current density, and poor product selectivity for CO2 electroreduction greatly impede their practical applications. In this work, we develop an efficient catalyst for CO2 reduction to CO consisting of well-dispersed ZrO2 nanoparticles tightly anchored on nitrogendoped carbon nanosheets(ZrO2/N-C) for the first time. Importantly, the ZrO2 nanoparticles possess oxygen vacancies and defects, which regulate the electronic structure of catalyst and thus greatly enhance the electrocatalytic activity. Specifically, ZrO2/N-C demonstrates a high CO Faradaic efficiency(FE) of 64% at-0.4 V vs. the reversible hydrogen electrode(RHE) and a respectable current density of ~2.6 m A cm-2 in CO2-saturated 0.5 M KHCO 3 solution. This work opens a new avenue for developing excellent catalysts for CO2 electroreduction with metal oxide/heteroatom-doped carbon composite structure. | Zhengpei Miao Pei Hu Chuanye Nie Huan Xie Wenli Fu Qing Li | 2019 | Journal of Energy Chemistry2019，28，11： | 3 |
| 7 | Wheat-RegNet:An encyclopedia of common wheat hierarchical regulatory networks显示文摘Dear Editor,Common wheat(Triticum aestivum,2n=6×=42,AABBDD)is the staple crop worldwide.Elucidating the gene regulatory network provides essential information for mechanism studies and targeted manipulation of gene activity for breeding.However,it is a challenging task given the extremely large(16 Gb)and complicated allohexaploid genome of common wheat.Integrating multi-omics data is a compelling approach to construct the hierarchical regulatory network. | Tengfei Tang Shilong Tian Haoyu Wang Xiaotong Lv Yilin Xie Jinyi Liu Meiyue Wang Fei Zhao Wenli Zhang Hao Li Yijing Zhang | 2023 | Molecular Plant2023，16，2： | 1 |
| 8 | Overview on Wavelet Image Denoising显示文摘 | Xie Jiecheng Zhang Dali Xu Wenli | 2002 | Journal of Image and Graphics2002，7，3： | 1 |
| 9 | Overview on Wavelet Image Denoising显示文摘 | Xie Jiecheng Zhang Dali Xu Wenli | 2002 | Journal of Image and Graphics2002，7，3： | 1 |
| 10 | Neuroprotective Effects of a Standardized Extract of Diospyros kaki Leaves on MCAO Transient Focal Cerebral Ischemic Rats and Cultured Neurons Injured by Glutamate or Hypoxia显示文摘 | Weijian Bei Wenlie Peng Linquan Zang Zhiyong Xie Dehui Hu Anlong Xu | 2007 | Planta Med2007，，07： | 1 |
| 11 | Spatially adaptive Wavelet Denoising Using the Minimum Description Length Principle显示文摘 | Jiecheng Xie Dali Zhang Wenli Xu | 2004 | IEEE Trans Image Processing2004，13，2： | 1 |
| 12 | Community Characteristics and Species Diversity of Wetland Plants in the Yangguan Nature Reserve of Dunhuang显示文摘As a typical inland wetland, Yangguan nature reserve wetland in Dunhuang is one of the important stops of migratory route for birds, which is vulnerable and particular. Study on the community characteristics and species diversity of wetland has great signifi cance for biodiversity protection. Based on the fi eld investigation, the fl oristic composition, geographical elements and species diversity of wetland plants were studied in Yangguan reserve of Dunhuang. The results showed that 26 families, 56 genera and 74 species were recorded in the study area. The largest families were the Gramineae and Chenopodiaceae, accounting for 29.73% of the total. Herbs were the most abundant life-form, accounting for 77.03% of the total. The fl oral geographical elements of the plants were mainly composed of temperate zone distribution type. By using two way indicator species analysis(TWINSPAN), the vegetation in 36 sampling plots could be classifi ed into 8 communities. The species diversity indexes of communities were relatively low, but had large differences among each other. According to the importance value, the Margalef richness index(Rm) ranged from 0 to 4.200. Simpson diversity index(D) was between 0 and 0.512; Shannon diversity index(H) ranged from 0 to 1.400, and Pielou evenness index(J) was within the range of 0.538 to 1.000. The results indicated that the plant species were relatively rare and simple in general, the species diversity of communities was low, and the ecological environment was fragile in Yangguan nature reserve of Dunhuang. | DAI Xueling ZHAO Tingwei MA Shoushi LIU Xingwen YANG Jinwu MA Haitao HE Wenli YANG Jing DUAN Hongling XIE Jianping | 2016 | Journal of Landscape Research2016，8，2： | 1 |
| 13 | Super-assembly of integrated gold magnetic assay with loopmediated isothermal amplification for point-of-care testing显示文摘With the increasing global threat of various diseases and infections,it is essential to develop a fast,low-cost,and easy-to-use point-of-care testing(POCT)system for inspections at all levels of medical institutions and self-examination at home.In this work,gold magnetic nanoparticles(GMNPs)are used as the key material,and a rapid visual detection method is designed through integrating loop-mediated isothermal amplification(LAMP)and lateral flow assay(LFA)biosensor for detecting a variety of analytes which includes whole blood,buccal swabs,and DNA.It is worth to note that the proposed method does not need DNA extraction.Furthermore,uracil DNA glycosylase(UDG)is employed to eliminate carrier contamination for preventing false positive results.The whole detection process can be finished within 25 min.The accuracy of detection is measured by assessing the polymorphisms of the methylenetetrahydrofolate reductase(MTHFR)C677T.The detection limit of the newly developed extraction-free detection system for MTHFR C677T is 0.16 ng/μL.A preliminary clinical study of the proposed method is carried out by analyzing 600 clinical samples(including 200 whole blood samples,100 buccal swabs,and 300 genomic DNA samples).The results indicate that the proposed method is 100%consistent with the sequencing results which provides a new choice for POCT and shows a broad application prospect in all levels of medical clinics and at home. | Jianping Liang Jie Zeng Xiaojuan Huang Tengteng Zhu Yonglong Gong Chen Dong Xiangrong Wang Lingzhi Zhao Lei Xie Kang Liang Qiongxiang Tan Yali Cui Biao Kong Wenli Hui | 2023 | Nano Research2023，16，1： | 0 |
| 14 | Photoluminescence Enhancement of Aluminum Ion Intercalated MoS_(2)Quantum Dots显示文摘Low photolumines-cence(PL)quantum yield of molybdenum disulfide(MoS_(2))quan-tum dots(QDs)has lim-ited practical applica-tion as potential fluores-cent materials.Here,we report the intercalation of aluminum ion(Al^(3+))to enhance the PL of MoS_(2)QDs and the un-derlying mechanism.With detailed characterization and exciton dynamics study,we suggest that additional surface states including new emission centers have been effectively introduced to MoS_(2)QDs by the Al^(3+)intercalation.The synergy of new radiative pathway for exciton re-combination and the passivation of non-radiative surface traps is responsible for the en-hanced fluorescence of MoS_(2)QDs.Our findings demonstrate an efficient strategy to improve the optical properties of MoS_(2)QDs and are important for understanding the regulation effect of surface states on the emission of two dimensional sulfide QDs. | Yanmin Kuang Wenli He Zhichao Zhu Yaru Chen Dongwei Ma Xiaojuan Wang Lijun Guo Yulu He Zhen Chi Xia Ran Luogang Xie | 2023 | Chinese Journal of Chemical Physics2023，36，5： | 0 |
| 15 | Non-integrating lentiviral vectors based on the minimal S/MAR sequence retain transgene expression in dividing cells显示文摘Safe and efficient gene transfer systems are the basis of gene therapy applications. Non-integrating lentiviral(NIL) vectors are among the most promising candidates for gene transfer tools, because they exhibit high transfer efficiency in both dividing and non-dividing cells and do not present a risk of insertional mutagenesis. However, non-integrating lentiviral vectors cannot introduce stable exogenous gene expression to dividing cells, thereby limiting their application. Here, we report the design of a non-integrating lentiviral vector that contains the minimal scaffold/matrix attachment region(S/MAR) sequence(SNIL), and this SNIL vector is able to retain episomal transgene expression in dividing cells. Using SNIL vectors, we detected the expression of the eGFP gene for 61 days in SNIL-transduced stable CHO cells, either with selection or not. In the NIL group without the S/MAR sequence, however, the transduced cells died under selection for the transient expression of NIL vectors. Furthermore,Southern blot assays demonstrated that the SNIL vectors were retained extrachromosomally in the CHO cells. In conclusion,the minimal S/MAR sequence retained the non-integrating lentiviral vectors in dividing cells, which indicates that SNIL vectors have the potential for use as a gene transfer tool. | Zhen Xu Feng Chen Lingling Zhang Jing Lu Peng Xu Guang Liu Xuemin Xie Wenli Mu Yajun Wang Depei Liu | 2016 | Science China(Life Sciences)2016，59，10： | 0 |
| 16 | Enhancing electromagnetic absorption performance of Molybdate@Carbon by metal ion substitution显示文摘Transition metal molybdate(RMoO4)has been extensively studied in optics,electricity and catalysis due to its low cost and multivalent Mo atoms,while its poor electrical conductivity limits its application in electromagnetic wave absorption(EMA).Compounding molybdate with conductive materials is an effective way to improve its electrical conductivity.In this work,a homogeneous coating on the molybdate surface was achieved by utilizing a pyrrole oxidation polymerization mechanism,and then stabilized composites of Molybdate@Carbon(RMoO4@C)were obtained by high-temperature pyrolysis.The EMA properties of the nanocomposites were tuned by substituting the species of transition metal elements(RMoO_(4)@C,R=Fe,Co,Cu).Among them,Fe_(2)(MoO_(4))_(3)@C has a minimum reflection loss of−60.62 dB at an ultra-low thickness of 1.7 mm,and the effective absorption bandwidth(EAB)can reach 4.75 GHz at 3.00 mm.This work expands the range of applications for molybdate and provides a new material basis for building high-performance EMA materials. | Aming Xie Daohu Sheng Wenli Liu Youjian Chen Siyao Cheng | 2023 | Journal of Materials Science & Technology2023，，32： | 0 |
| 17 | Returning the Land to the Scenery: Contemporary Strategy of Architectural Landscape Integration显示文摘In general,architecture and land are two opposite sides,and a very important manifestation of the increasingly prominent contradiction between man and land is the contradiction between architecture and land.Traditional architectural landscape integration focuses on the relationship between architecture and environmental landscape.As the carrier of landscape and architecture,the integration of land and architecture is rarely mentioned.The integration of architecture and land to form an integrated architectural landscape has become an important creative strategy of contemporary pioneer architects.By exploring the relationship between architecture and land from the perspective of architectural landscape integration,it helps the architectural community to solve the contradiction between architecture and land. | ZHONG Xinping XIE Wenli YAN Weili | 2021 | Journal of Landscape Research2021，13，5： | 0 |
| 18 | High dietary lipid level promotes low salinity adaptation in the marine euryhaline crab(Scylla paramamosain)显示文摘The physiological processes involved in adaptation to osmotic pressure in euryhaline crustaceans are highly energy demanding,but the effects of dietary lipids(fat)on low salinity adaptations have not been well evaluated.In the present study,a total of 120 mud crabs(Scylla paramamosain,BW=17.87±1.49 g)were fed control and high-fat(HF)diets,at both medium salinity(23‰)and low salinity(4‰)for 6 wk,and each treatment had 3 replicates with each replicate containing 10 crabs.The results indicated that a HF diet significantly mitigated the reduction in survival rate,percent weight gain and feed efficiency induced by low salinity(P<0.05).Low salinity lowered lipogenesis and activated lipolysis resulting in lipid depletion in the hepatopancreas of mud crabs(P<0.05).Thus,HF diets enhanced the process of lipolysis to supply more energy.In the gills,low salinity and the HF diet increased the levels of mitochondrial biogenesis markers,the activity of mitochondrial complexes,and the expression levels of genes related to energy metabolism(P<0.05).Consequently,the positive effects of the HF diet on energy metabolism in mud crabs at low salinity promoted osmotic pressure regulation.Specifically,significantly higher haemolymph osmotic pressure and inorganic ion content,as well as higher osmotic pressure regulatory enzyme activity in gills,and gene and protein expression levels of NaK-ATPase were observed in crabs fed the HF diet at low salinity(P<0.05).In summary,high dietary lipid levels improved energy provision to facilitate mitochondrial biogenesis,which increased ATP provision for osmotic pressure regulation of mud crabs.This study also illustrates the importance of dietary lipid nutrition supplementation for low salinity adaptations in mud crabs. | Jiaxiang Luo Chen Ren Tingting Zhu Chen Guo Shichao Xie Yingying Zhang Zheng Yang Wenli Zhao Xiangsheng Zhang Jingjing Lu Lefei Jiao Qicun Zhou Douglas R.Tocher Min Jin | 2023 | Animal Nutrition2023，，1： | 0 |
| 19 | Lattice-based autonomous path proxy re-encryption in the standard model显示文摘Autonomous path proxy re-encryption(AP-PRE)is a type of PRE that implements control on the delegation path in a multi-hop PRE.AP-PRE forces the proxy to perform the transformation along a predefined path without revealing the underlying plaintext.There are several applications of AP-PRE,including electronic medical systems,data sharing,and email systems.However,as far as we know,the existing AP-PRE scheme is provably secure in the random oracle model under the classical number-theoretic assumption,which might be vulnerable to quantum computers.Therefore,it raises the intriguing question of how to construct a quantum-resistant AP-PRE scheme.In this study,we proposed an AP-PRE scheme based on the widely accepted quantum-resistant learning with errors(LWE)assumptions.Our scheme supports the polynomial length of the delegation path.Furthermore,our scheme is proved to be selective-path CPA(sCPA)secure in the standard model under LWE assumptions. | Wenli XIE Jian WENG Yao TONG Xiaojian LIANG Lisha YAO Feixiang ZHAO | 2023 | Science China(Information Sciences)2023，66，10： | 0 |
| 20 | Loss of NEIL3 activates radiotherapy resistance in the progression of prostate cancer显示文摘Objective:To explore the genetic changes in the progression of castration-resistant prostate cancer(CRPC)and neuroendocrine prostate cancer(NEPC)and the reason why these cancers resist existing therapies.Methods:We employed our CRPC cell line microarray and other CRPC or NEPC datasets to screen the target gene NEIL3.Lentiviral transfection and RNA interference were used to construct overexpression and knockdown cell lines.Cell and animal models of radiotherapy were established by using a medical electron linear accelerator.Flow cytometry was used to detect apoptosis or cell cycle progression.Western blot and qPCR were used to detect changes in the protein and RNA levels.Results:TCGA and clinical patient datasets indicated that NEIL3 was downregulated in CRPC and NEPC cell lines,and NEIL3 was correlated with a high Gleason score but a good prognosis.Further functional studies demonstrated that NEIL3 had no effect on the proliferation and migration of PCa cells.However,cell and animal radiotherapy models revealed that NEIL3 could facilitate the radiotherapy sensitivity of PCa cells,while loss of NEIL3 activated radiotherapy resistance.Mechanistically,we found that NEIL3 negatively regulated the expression of ATR,and higher NEIL3 expression repressed the ATR/CHK1 pathway,thus regulating the cell cycle.Conclusions:We demonstrated that NEIL3 may serve as a diagnostic or therapeutic target for therapy-resistant patients. | Qiong Wang Zean Li Jin Yang Shirong Peng Qianghua Zhou Kai Yao Wenli Cai Zhongqiu Xie Fujun Qin Hui Li Xu Chen Kaiwen Li Hai Huang | 2022 | Cancer Biology & Medicine2022，19，8： | 0 |
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