|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Advancement in separation materials for blood purification therapy显示文摘Blood purification refers to the extra corporeal therapies of removing potentially toxic substances, in which blood is circulated through an adsorption system loading separation materials. High-efficient inexpensive separation materials are critical to success. In this review, separation materials such as polymers and nanomaterials are summarized and compared. Combining the advantages of the adsorptive membranes and nanomaterials, organic–inorganic hybrid/blend membranes have been developed explosively. These hybrid/blend membranes have both the characteristics of high permeability, easy fabrication, good biocompatibility of adsorptive membranes, and characteristics of fast adsorption rate and high adsorption capacity of nanomaterials. The preparation and modification methodology of the separation materials is reviewed. For affinity separation materials, the relationship of ligand chemistry, ligand density and pores of the matrix is discussed. This paper also summarizes some interesting applications in separation materials for removal of bilirubin, endotoxin, toxic metal ions, cytokine, etc. | Jia Ju Feixue Liang Xiaoxin Zhang Ran Sun Xiaoguang Pan Xiaoyun Guan Guanning Cui Xuan He Mengyan Li | 2019 | Chinese Journal of Chemical Engineering2019，27，6： | 5 |
| 2 | Effects of Pseudoalteromonas sp. BC228 on Digestive Enzyme Activity and Immune Response of Juvenile Sea Cucumber(Apostichopus japonicus)显示文摘A marine bacterium, Pseudoalteromonas sp. BC228 was supplemented to feed in a feeding experiment aiming to determine its ability of enhancing the digestive enzyme activity and immune response of juvenile Apostichopus japonicus. Sea cucumber individuals were fed with the diets containing 0(control), 105, 107 and 109 CFU g-1 diet of BC228 for 45 days. Results showed that intestinal trypsin and lipase activities were significantly enhanced by 107 and 109 CFU g-1 diet of BC228 in comparison with control(P < 0.01). The phagocytic activity in the coelomocytes of sea cucumber fed the diet supplemented with 107 CFU g-1 diet of BC228 was significantly higher than that of those fed control diet(P < 0.05). In addition, 105 and 107 CFU g-1 diet of BC228 significantly enhanced lysozyme and phenoloxidase activities in the coelomic fluid of sea cucumber, respectively, in comparison with other diets(P < 0.01). Sea cucumbers, 10 each diet, were challenged with Vibrio splendidus NB13 after 45 days of feeding. It was found that the cumulative incidence and mortality of sea cucumber fed with BC228 containing diets were lower than those of animals fed control diet. Our findings evidenced that BC228 supplemented in diets improved the digestive enzyme activity of juvenile sea cucumber, stimulated its immune response and enhanced its resistance to the infection of V. splendidus. | MA Yuexin SUN Feixue ZHANG Congyao BAO Pengyun CAO Shuqing ZHANG Meiyan | 2014 | Journal of Ocean University of China2014，13，6： | 4 |
| 3 | Continuous and comprehensive atmospheric observations in Beijing:a station to understand the complex urban atmospheric environment显示文摘Due to profound impact on climate and human health,air quality has attracted attention from all levels of the civil society.The key step in the provision of required tools for the society to tackle the complex air quality problem is to characterize it in a comprehensive manner with a long-term perspective.Here,we describe a continuous and comprehensive observation station and its accompanying state-ofthe-art instrumentation that was established to investigate the complex urban atmospheric environment in a rapidly developing Chinese Megacity.The station,located in downtown Beijing,aims to study air quality by identifying the major atmospheric pollutants and key processes determining their formation and loss mechanisms.A few hundreds of parameters are continuously measured with the state-of-the-art instruments,including trace gas concentrations,aerosol particle size distributions,and mass concentrations,covering aerosol particle chemical composition from molecules to micrometer-sized aerosol particles.This produced long-term,comprehensive big data with around 1�10^(11)bytes per year.In this paper,we provide an overview on the facilities of the station,the instrumentation used,the workflow of continuous observations and examples of results from 2018 to 2019 and a basis for establishing a modern long-term,comprehensive atmospheric urban observation station in other megacities. | Yongchun Liu Chao Yan Zemin Feng Feixue Zheng Xiaolong Fan Yusheng Zhang Chang Li Ying Zhou Zhuohui Lin Yishou Guo Ying Zhang Li Ma Wenshuo Zhou Zhikun Liu Lubna Dada Kaspar Dallenbach Jenni Kontkanen Runlong Cai Tommy Chan Biwu Chu Wei Du Lei Yao Yonghong Wang Jing Cai Juha Kangasluoma Tom Kokkonen Joni Kujansuu Anton Rusanen Chenjuan Deng Yueyun Fu Rujing Yin Xiaoxiao Li Yiqun Lu Yiliang Liu Chaofan Lian Dongsen Yang Weigang Wang Maofa Ge Yuesi Wang Douglas R.Worsnop Heikki Junninen Hong He Veli-Matti Kerminen Jun Zheng Lin Wang Jingkun Jiang Tuukka Petaja Federico Bianchi Markku Kulmala | 2020 | Big Earth Data2020，4，3： | 3 |
| 4 | Expression of S100A10 gene and its regulation by sex hormones in mouse uterus显示文摘S100A10 belongs to the S100 calcium binding protein superfamily, and functions as one of the mediators of calcium-dependent signaling pathway. Recently, S100A10 gene was proved to be significantly up-regulated at the implantation site. In the present study, semi-quantitative reverse transcriptase-polymerase chain reaction and in situ hybridization are used to investigate the tissue-specificity of S100A10 expression and the expression pattern of S100A10 in the uteri during the estrous cycle and pregnancy. Meanwhile, the regulation of S100A10 expression by sex steroid hormones is studied in ovariectomized mice. The results show that S100A10 could be detected in various kinds of tissues, with relatively high expression in reproductive tracts including ovary, uterus, testis and epididymis.During pregnancy, the expression of S100A10 in the uteri is significantly up-regulated on the 4th day. The transcript is strongly detected in endometrial stromal cells and weakly in luminal epithelium cells at the implantation site, but almost not at the inter-implantation site.From gestational day 5 till labor, S100A10 mRNA maintains a certain level in both uteri and placentae. During the estrous cycle, expression of S100A10 is up-regulated in the uteri at proestrus and estrus. Estradiol significantly induces the expression of S100A10, while progesterone can abolish the effect of estradiol. The data suggests that S100A10 may be involved in preventing luminal epithelial cells from over-apoptosis, inducing proliferation and decidualization of stromal cells during implantation, and responding to reproductive stress triggered by copulation. | CHEN Zhiqiang LIU Jing LI Feixue SUN Xiaoyang ZHANG Huaiyun WANG Yanling | 2005 | Progress in Natural Science:Materials International2005，15，10： | 2 |
| 5 | Ownership Structure and Firm Value in China's Privatized Firms:1991-2001 显示文摘 | Wei Zuobao Feixue Xie and Shaorong Zhang | 2005 | Journal of Financial and Quantitative Analysis2005，40，1： | 1 |
| 6 | Ownership structure and firm value in China's privatized firms:1991-2001显示文摘 | Wei Zuobao Xie Feixue Zhang Shaorong | 2005 | Journal of Financial & Quantitative Analysis2005，40，1： | 1 |
| 7 | DDR1 promotes LoVo cell proliferation by regulating energy metabolism显示文摘Cellular energy metabolism dysregulation is associated with colorectal cancer(CRC)development and progression.Discoidin domain receptor 1a(DDR1a),one of the five DDR1 isoforms,is closely related to cell proliferation,invasion,and apoptosis in various tumors.Whether it participates in cellular metabolic reprogramming and regulates CRC initiation and progression remains unclear.In this study,we compared the expression of DDR1 in CRC tissues and adjacent tissues from 126 postoperative CRC samples.Moreover,lentivirus-mediated DDR1a overexpression and knockdown were performed in LoVo cells,and cell viability and proliferation were determined by CCK-8 and BrdU assays,respectively.Oxygen consumption rate,extracellular acidification rate,and lactate production were used to determine the effect of DDR1a on metabolic reprogramming.Clinically,CRC patients with high DDR1 expression had poor differentiation and were at an advanced TNM stage.DDR1a promoted LoVo cell proliferation,mitochondrial function,and extracellular acidification.Moreover,DDR1a knockdown inhibited intracellular lactic acid production in LoVo cells,while a pyruvate kinase inhibitor(diamide,200μM)significantly reversed this progression.Taken together,our results reveal that DDR1 plays a crucial role in maintaining intracellular environment homeostasis through metabolic reprogramming. | Bin Xiong Zehui Xie Feixue Song Huiling Chen Xiaojuan Wang Zhengxu Jin Tiyun Han Yi Li Dekui Zhang | 2022 | Acta Biochimica et Biophysica Sinica2022，54，5： | 1 |
| 8 | Ownership Structure and Firm Value in China's Privatized Firms:1991-2001显示文摘 | FEIXUE XIE SHAORONG ZHANG | 2005 | Journal of Financial and Quantitative Analysis2005，40，1： | 1 |
| 9 | Ownership Strcture and Firm Value in China's Privatized Firms: 1991-2001显示文摘 | Wei Zuobao Xie Feixue and Zhang Shaorong 2005 | 2005 | Journal of Financial and Quantitative Analysis2005，3，1： | 1 |
| 10 | Multiplexing performance assessment of POCET method for Compass B1/B3 signals 显示文摘 | ZHANG Kai ZHOU Hongwei WANG Feixue | 2011 | The Journal of Navigation2011，64，10： | 1 |
| 11 | Ameliorative effect of scutellarin on acute alcohol brain injury in mice显示文摘Drinking culture has high significance in both China and the world,whether in the entertainment sector or in social occasions;according to the World Health Organization's 2018 Global Alcohol and Health Report,about 3 million people died from excessive drinking in 2016,accounting for 5.3%of the total global deaths that year.Oxidative stress and inflammation are the most common pathological phenomena caused by alcohol abuse(Snyder et al.,2017). | Tianmeng ZHANG Kun WANG Hui FAN Qiankun YANG Xiao ZHANG Feixue LIU Xin FENG Yi CHEN Daoyang TENG Panpan ZHAO Jingquan DONG | 2022 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2022，23，3： | 1 |
| 12 | Ownership Structure and Firm Value in China's Privatized Firms: 1991-2001 显示文摘 | Zuobao Wei Feixue Xie and Shaorong Zhang | 2005 | JOURNAL OF FINANCIAL AND QUANTITATIVE ANALYSIS2005，3，： | 1 |
| 13 | Ownership Structure and Firm Value in China' s Privatized Firms: 1991-2001 显示文摘 | Zuobao Wei Feixue Xie and Shaorong Zhang | 2005 | Journal of Finan- cial and Quantitative Analysis2005，，40： | 1 |
| 14 | Ownership Structure and Firm Value in China' s Privatized Firms 显示文摘 | Wei Zuobao Xie Feixue Zhang Shaorong | 2005 | Journal of Financial and Quantitative Analysis2005，40，1： | 1 |
| 15 | Insights into Photothermally Enhanced Photocatalytic U(VI)Extraction by a Step-Scheme Heterojunction显示文摘In this work,a CdS/BivO4 step-scheme(S-scheme)heterojunction with self-photothermally enhanced photocatalytic effect was synthesized and applied for efficient U(VI)photoextraction.Characterizations such as transient absorption spectroscopy and Tafel test together confirmed the formation of S-scheme heterojunctions,which allows CdS/BivO_(4) to avoid photocorrosion while retaining the strong reducing capacity of CdS and the oxidizing capacity of BivO_(4).Experimental results such as radical quenching experiments and electron spin resonance show that U(VI)is rapidly oxidized by photoholes/·OH to insoluble UO(OH)2 after being reduced to U(IV)by photoelectrons/·O2,which precisely avoids the depletion of electron sacrificial agents.The rapid recombination of electron-hole pairs triggered by the S-scheme heterojunction is found to release large amounts of heat and accelerate the photocatalysis.This work offers a new enhanced strategy for photocatalytic uranium extraction and presents a direction for the design and development of new photocatalysts. | Yifeng Zhang Haorong Sun Feixue Gao Shuo Zhang Qingzhi Han Jing Li Ming Fang Yawen Cai Baowei Hu Xiaoli Tan Xiangke Wang | 2023 | Research2023，，1： | 0 |
| 16 | Historical and current climates affect the spatial distribution of herbivorous tree insects in China显示文摘Historical and current climate impacts reshape the evolutionary trajectory and ecological dynamics of entire vegetative communities,which can drive insect species distribution.Understanding the spatial distribution of insects can enhance forest management effectiveness.The effects of historical and current climates in the spatial distribution of herbivorous tree insects in China were explored.A species distribution model simulated insect spatial distribution based on 596 species and the distribution probability and richness of these species were assessed in forest ecoregions.The explanatory power of the historical climate was stronger than that of the current climate,particularly historical annual precipitation and annual mean temperatures,for the distribution of herbivorous insects.Under both historical and current climatic conditions,herbivorous tree insects were and are mainly distributed in the North China Plain and the middle and lower reaches of the Yangtze River Plain,namely in the Huang He Plain mixed forests,Changjiang Plain evergreen forests,and Sichuan Basin evergreen broadleaf forests.The Yunnan-Guizhou Plateau and northeast China are regions with large impact differences between historical and current climates.The findings of this study provide valuable insights into herbivorous insect responses to sustained climate change and may contribute to long-term biodiversity conservation activities. | Feixue Zhang Chunjing Wang Jizhong Wan | 2023 | Journal of Forestry Research2023，34，5： | 0 |
| 17 | Biological calcium phosphate nanorods for piezocatalytical extraction of U(VI)from water显示文摘The application of nanomaterials in energy and environmental fields has recently made great progress.As a key element in the nuclear industry,the discharge of uranium(U(VI))contained wastewater usually induces environmental issues and waste of resources.Although the catalytically generated H_(2)O_(2)by nanomaterials has recently shown application potential in extracting U(VI)from water,low-cost and highly efficient nanocatalysts are still urgently needed.In this work,a cheap and readily available piezocatalyst of calcium phosphate nanorods was successfully fabricated by calcining chicken bones.Under ultrasonication,H_(2)O_(2)was produced and used to extract U(VI)from water.It is worth noting that the yield of H_(2)O_(2)reached 179.7μmol·g^(−1)·h^(−1),and the extraction efficiency of U(VI)in water reached 97.16%(100 ppm)within 330 min.Through the capture and quantitative analysis of the active species,it is found that the generation of H_(2)O_(2)depends on the combination of soluble oxygen and piezoelectrons,which thus dominates the extraction of U(VI).This simple and powerful piezocatalytic strategy greatly reduces the cost of H_(2)O_(2)production for U(VI)extraction in water,and is of great significance for the treatment of U(VI)-containing wastewater. | Feixue Gao Zhe Wang Ming Fang Xiaoli Tan Shao Hui Xu Mao Liu Guang Tao Fei Li De Zhang | 2023 | Nano Research2023，16，11： | 0 |
| 18 | Liensinine alleviates septic heart injury by targeting inflammation,oxidative stress,apoptosis,and autophagy显示文摘Sepsis is one of the most commonly discussed worldwide health issues,with high rates of morbidity and mortality[1].Severe sepsis can trigger a systemic inflammatory response,which can result in organ failure and death in a short time.Of all organs,the heart is one of the most vulnerable target organs during sepsis[2].Previous research has revealed that sepsis-induced heart damage is often accompanied by uncontrolled inflammation,oxidant/antioxidant imbalance,excessive apoptosis,and autophagy. | Wei Zhang Tianling Wang Huizhen Chen Hui Fan Feixue Liu Xiao Zhang Haitao Yang Xueqing Li Zibo Dong Jingquan Dong | 2023 | Acta Biochimica et Biophysica Sinica2023，55，3： | 0 |
| 19 | Efficacy of bioactive compounds of Chaihu(Radix Bupleuri Chinensis)on glaucomatous optic atrophy through interleukin-6/hypoxia inducible factor-1αsignal pathway显示文摘OBJECTIVE:To investigate the bioactive compounds of Chaihu(Radix Bupleuri Chinensis)(RB)on glaucomatous optic atrophy(GOA),and to study the pharmacological mechanism.METHODS:We collected information on the bioactive compounds of RB from the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform(TCMSP).Targets related to bioactive compounds and GOA were also obtained.Gene Ontology(GO),Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway and network analyses were performed to investigate the potential mechanism of RB against GOA.Subsequently,the main bioactive compounds of RB and targets of GOA were docked by Autodock software.Moreover,a GOA model of retinal ganglion cells(RGCs)induced by cobalt chloride was established to verify the effect of RB on GOA.RESULTS:There were 17 main bioactive compounds and 46 key targets were screened as potential players in GOA.The compound-target network mainly contained 17 compounds and 46 corresponding targets,and the key targets consisted of interleukin-6(IL-6),hypoxia inducible factor-1α(HIF1A),Caspase-3,estrogen receptor alpha(ESR1),MYC proto-oncogene(MYC),and vascular endothelial growth factor A(VEGFA).Forty-nine significantly enriched GO terms,and 134 KEGG signaling pathways were identified(P<0.05),including HIF-1,tumor necrosis factor,VEGF,prolaction,and other signaling pathways.Molecular docking results showed that the main bioactive compounds of RB exhibited the strongest binding activity with IL-6.Furthermore,experimental validation showed that the RB extract inhibited the activity and promoted apoptosis of RGCs in a dose-dependent manner.The RB extract also suppressed the expression of Bax,Caspase-3,and Caspase-9 and regulated malonaldehyde,superoxide dismutase,and glutathione peroxide by inhibiting the IL-6/HIF-1αsignaling pathway.CONCLUSIONS:The present study provided insights into the mechanism of RB on GOA.RB mainly reverses GOA by inhibiting the IL-6/HIF-1αsignaling pathway. | YANG Xirui ZHAO Hui SHAN Muhammad DONG Feixue ZHANG Dandan WANG Jixue YUAN Xingxing | 2023 | Journal of Traditional Chinese Medicine2023，43，6： | 0 |
| 20 | The Influence of IFN-α on Blood Plasmacytoid Dendritic Cell in Chronic Myeloid Leukaemia显示文摘OBJECTIVE To study the mechanism of IFN on CML.METHODS Samples of 15 CML patients and 10 healthy controlswere studied. The flow cytometry was performed to identifycirculating pDCs. The concentration of IFN-α in serum and that inthe supernatant of peripheral blood mononuclear cells (PBMCs)cultured after stimulation with CpG ODN2216 were examinedboth in CML patients and in the healthy controlsRESULTS There was significant reduction in the numberof circulating pDCs, serum concentration of IFN-α and thecapacity of IFN-α producing PBMCs in CML patients comparedwith those in healthy control individuals (P < 0.001). After theactive treatment with IFN-α and hydroxyurea, the quantity andfunction of pDCs were increased in stabilized patients, especiallythe function of pDCs in 2 patients achieving major cytogeneticresponse (MCR). The proportion and function of pDCs and theserum levels of IFN were inversely correlated with both WBC andage of the patients with CML, and positively correlated with thestate of the illness.CONCLUSION CML patients had a reduced number anddysfunction of circulating pDCs. The active treatment with IFN inCML patients may be related to the restoration of pDCs. | Chongyang Wu Liansheng Zhang Ye Chai Feixue Song Pengyun Zeng Lijuan Li Lingling Yue Bin Xiong | 2009 | Chinese Journal of Clinical Oncology2009，6，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员