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| 1 | Prototype for 5G New Air Interface Technology SCMA and Performance Evaluation显示文摘Sparse code multiple access(SCMA) is a novel non-orthogonal multiple access scheme proposed to meet the challenging demand of the future 5G communications, especially in support of the massive connections. The coded bits from each data stream will be directly mapped as multi-dimensional SCMA codeword in complex domain and then spread onto the physical resource elements in a sparse manner. The number of codewords that can be nonorthogonally multiplexed in one SCMA block can be made much larger than the number of orthogonal resource elements therein, resulting in an overloaded system. The sparsity in the spreading pattern and the design in the multidimensional modulator jointly ensure the SCMA codewords can be robustly decoded with low complexity. In this paper, we focus on the low complexity receiver design and verified the superior of an SCMA system via simulations and real-time prototyping. Lab tests and field tests all show that SCMA is a promising candidate for 5G non-orthogonal multiple access which can provide up to 300% overloading that triples the whole system throughput while still enjoying the link performance close to orthogonal transmissions. | LU Lei CHEN Yan GUO Wenting YANG Huilian WU Yiqun XING Shuangshuang | 2015 | China Communications2015，12，S1： | 15 |
| 2 | Research on power electronic transformer applied in AC/DC hybrid distribution networks显示文摘The AC/DC hybrid distribution network is one of the trends in distribution network development, which poses great challenges to the traditional distribution transformer. In this paper, a new topology suitable for AC/DC hybrid distribution network is put forward according to the demands of power grid, with advantages of accepting DG and DC loads, while clearing DC fault by blocking the clamping double sub-module(CDSM) of input stage. Then, this paper shows the typical structure of AC/DC distribution network that is hand in hand. Based on the new topology, this paper designs the control and modulation strategies of each stage, where the outer loop controller of input stage is emphasized for its twocontrol mode. At last, the rationality of new topology and the validity of control strategies are verified by the steady and dynamic state simulation. At the same time, the simulation results highlight the role of PET in energy regulation. | Yiqun Miao Jieying Song Haijun Liu Zhengang Lu Shufan Chen Chun Ding Tianzhi Cao Linhai Cai Yuzhong Gong | 2018 | Global Energy Interconnection2018，1，3： | 14 |
| 3 | Chromosome-level genome of Himalayan yew provides insights into the origin and evolution of the paclitaxel biosynthetic pathway显示文摘Taxus,commonly known as yew,is a well-known gymnosperm with great ornamental and medicinal value.In this study,by assembling a chromosome-level genome of the Himalayan yew(Taxus wallichiana)with 10.9 Gb in 12 chromosomes,we revealed that tandem duplication acts as the driving force of gene family evolution in the yew genome,resulting in the main genes for paclitaxel biosynthesis,i.e.those encoding the taxadiene synthase,P450s,and transferases,being clustered on the same chromosome.The tandem duplication may also provide genetic resources for the nature to sculpt the core structure of taxoids at different positions and subsequently establish the complex pathway of paclitaxel by neofunctionalization.Furthermore,we confirmed that there are two genes in the cluster encoding isoenzymes of a known enzyme in the paclitaxel biosynthetic pathway.The reference genome of the Himalayan yew will serve as a platform for decoding the complete biosynthetic pathway of paclitaxel and understanding the chemodi-versity of taxoids in gymnosperms. | Jian Cheng Xiao Wang Xiaonan Liu Xiaoxi Zhu Zihe Li Huanyu Chu Qian Wang QianQian Lou Bijun Cai Yiqun Yang Xiaoyun Lu Kai Peng Dingyu Liu Yuwan Liu Lina Lu Huan Liu Ting Yang Qijin Ge Chengcheng Shi Guichun Liu Zhiwei Dong Xun Xu Wen Wang Huifeng Jiang Yanhe Ma | 2021 | Molecular Plant2021，14，7： | 6 |
| 4 | North Pacific Eastern Subtropical Mode Water simulation and future projection显示文摘The present climate simulation and future projection of the Eastern Subtropical Mode Water(ESTMW) in the North Pacific are investigated based on the Geophysical Fluid Dynamics Laboratory Earth System Model(GFDL-ESM2M). Spatial patterns of the mixed layer depth(MLD) in the eastern subtropical North Pacific and the ESTMW are well simulated using this model. Compared with historical simulation, the ESTMW is produced at lighter isopycnal surfaces and its total volume is decreased in the RCP8.5 runs, because the subduction rate of the ESTMW decreases by 0.82×10-6 m/s during February–March. In addition, it is found that the lateral induction decreasing is approximately four times more than the Ekman pumping, and thus it plays a dominant role in the decreased subduction rate associated with global warming. Moreover, the MLD during February–March is banded shoaling in response to global warming, extending northeastward from the east of the Hawaii Islands(20°N, 155°W) to the west coast of North America(30°N, 125°W), with a maximum shoaling of 50 m, and then leads to the lateral induction reduction. Meanwhile, the increased northeastward surface warm current to the east of Hawaii helps strengthen of the local upper ocean stratification and induces the banded shoaling MLD under warmer climate. This new finding indicates that the ocean surface currents play an important role in the response of the MLD and the ESTMW to global warming. | XIA Ruibin LIU Qinyu XU Lixiao LU Yiqun | 2015 | Acta Oceanologica Sinica2015，34，3： | 5 |
| 5 | Integration of nanoscale light emitters:an efficient ultraviolet and blue random lasing from NaYF_4:Yb/Tm hexagonal nanocrystals显示文摘Near infrared light-controlled release of payloads from ultraviolet-sensitive(UV-sensitive) polymer hydrogels or nanocarriers is one of the most promising strategies for biotherapy. Here, we propose the concept of light activation of NaYF_4:20%Yb, 2%Tm nanocrystals(NCs). NaYF_4:20%Yb, 2%Tm NCs are synthesized by a solvothermal method. Effective upconversion luminescence from NaYF_4:20%Yb, 2%Tm NCs excited by a continuous wave(CW) 980 nm laser is obtained. The NaYF_4:20%Yb, 2%Tm NCs are then used as a laser gain medium and sandwiched between Al and quartz reflectors to form laser microcavities. UV and blue upconverted random lasing is obtained from the laser microcavities. Hence, we verify explicitly that the NaYF_4:Yb, Tm NCs support UV and blue upconversion random lasing via a 980 nm nanosecond laser excitation. Our work provides what we believe is a new concept for precision and localized cancer therapy by external light excitation. | YA-PEI PENG WEI LU PENGPENG REN YIQUN NI YUNFENG WANG LONG ZHANG YU-JIA ZENG WENFEI ZHANG SHUANGCHEN RUAN | 2018 | Photonics Research2018，6，10： | 4 |
| 6 | Continuous and comprehensive atmospheric observations in Beijing:a station to understand the complex urban atmospheric environment显示文摘Due to profound impact on climate and human health,air quality has attracted attention from all levels of the civil society.The key step in the provision of required tools for the society to tackle the complex air quality problem is to characterize it in a comprehensive manner with a long-term perspective.Here,we describe a continuous and comprehensive observation station and its accompanying state-ofthe-art instrumentation that was established to investigate the complex urban atmospheric environment in a rapidly developing Chinese Megacity.The station,located in downtown Beijing,aims to study air quality by identifying the major atmospheric pollutants and key processes determining their formation and loss mechanisms.A few hundreds of parameters are continuously measured with the state-of-the-art instruments,including trace gas concentrations,aerosol particle size distributions,and mass concentrations,covering aerosol particle chemical composition from molecules to micrometer-sized aerosol particles.This produced long-term,comprehensive big data with around 1�10^(11)bytes per year.In this paper,we provide an overview on the facilities of the station,the instrumentation used,the workflow of continuous observations and examples of results from 2018 to 2019 and a basis for establishing a modern long-term,comprehensive atmospheric urban observation station in other megacities. | Yongchun Liu Chao Yan Zemin Feng Feixue Zheng Xiaolong Fan Yusheng Zhang Chang Li Ying Zhou Zhuohui Lin Yishou Guo Ying Zhang Li Ma Wenshuo Zhou Zhikun Liu Lubna Dada Kaspar Dallenbach Jenni Kontkanen Runlong Cai Tommy Chan Biwu Chu Wei Du Lei Yao Yonghong Wang Jing Cai Juha Kangasluoma Tom Kokkonen Joni Kujansuu Anton Rusanen Chenjuan Deng Yueyun Fu Rujing Yin Xiaoxiao Li Yiqun Lu Yiliang Liu Chaofan Lian Dongsen Yang Weigang Wang Maofa Ge Yuesi Wang Douglas R.Worsnop Heikki Junninen Hong He Veli-Matti Kerminen Jun Zheng Lin Wang Jingkun Jiang Tuukka Petaja Federico Bianchi Markku Kulmala | 2020 | Big Earth Data2020，4，3： | 3 |
| 7 | High-performance all-polymer solar cells enabled by a novel low bandgap non-fully conjugated polymer acceptor显示文摘The non-fully conjugated polymer as a new class of acceptor materials has shown some advantages over its small molecular counterpart when used in photoactive layers for all-polymer solar cells(all-PSCs),despite a low power conversion efficiency(PCE)caused by its narrow absorption spectra.Herein,a novel non-fully conjugated polymer acceptor PFY-2TS with a low bandgap of~1.40 eV was developed,via polymerizing a largeπ-fused small molecule acceptor(SMA)building block(namely YBO)with a non-conjugated thioalkyl linkage.Compared with its precursor YBO,PFY-2TS retains a similar low bandgap but a higher LUMO level.Moreover,compared with the structural analog of YBO-based fully conjugated polymer acceptor PFY-DTC,PFY-2TS shows a similar absorption spectrum and electron mobility,but significantly different molecular crystallinity and aggregation properties,which results in optimal blend morphology with a polymer donor PBDB-T and physical processes of the device in all-PSCs.As a result,PFY-2TS-based all-PSCs achieved a PCE of 12.31%with a small energy loss of 0.56 eV enabled by the reduced non-radiative energy loss(0.24 eV),which is better than that of 11.08%for the PFY-DTC-based ones.Our work clearly demonstrated that non-fully conjugated polymers as a new class of acceptor materials are very promising for the development of high-performance all-PSCs. | Qunping Fan Ruijie Ma Tao Liu Jianwei Yu Yiqun Xiao Wenyan Su Guilong Cai Yuxiang Li Wenhong Peng Tao Guo Zhenghui Luo Huiliang Sun Lintao Hou Weiguo Zhu Xinhui Lu Feng Gao Ellen Moons Donghong Yu He Yan Ergang Wang | 2021 | Science China Chemistry2021，64，8： | 3 |
| 8 | Arabidopsis EXO70A1 recruits Patellin3 to the cell membrane independent of its role as an exocyst subunit显示文摘The exocyst is a well-known complex which tethers vesicles at the cell membrane before fusion. Whether an individual subunit can execute a unique function is largely unknown. Using yeast-two-hybrid(Y2H) analysis, we found that EXO70A1 interacted with the GOLD domain of Patellin3(PATL3). The direct EXO70A1-PATL3 interaction was supported by in vitro and in vivo experiments. In Arabidopsis, PATL3-GFP colocalized with EXO70A1 predominantly at the cell membrane, and PATL3 localization was insensitive to BFA and Try A23. Remarkably, in the exo70 a1 mutant, PATL3 proteins accumulated as punctate structures within the cytosol, which did not colocalize with several endomembrane compartment markers, and was insensitive to BFA. Furthermore, PATL3 localization was not changed in the exo70 e2, PRsec6 or exo84b mutants. These data suggested that EXO70A1, but not other exocyst subunits, was responsible for PATL3 localization,which is independent of its role in secretory/recycling vesicletethering/fusion. Both EXO70A1 and PATL3 were shown to bind PI4 P and PI(4,5)P2 in vitro. Evidence was obtained that the other four members of the PATL family bound to EXO70A1 as well, and shared a similar localization pattern as PATL3.These findings offered new insights into exocyst subunitspecific function, and provided data and tools for further characterization of PATL family proteins. | Chengyun Wu Lu Tan Max van Hooren Xiaoyun Tan Feng Liu Yan Li Yanxue Zhao Bingxuan Li Qingchen Rui Teun Munnik Yiqun Bao | 2017 | Journal of Integrative Plant Biology2017，59，12： | 3 |
| 9 | Role of Horizontal Density Advection in Seasonal Deepening of the Mixed Layer in the Subtropical Southeast Pacific显示文摘The mechanisms behind the seasonal deepening of the mixed layer(ML) in the subtropical Southeast Pacific were investigated using the monthly Argo data from 2004 to 2012. The region with a deep ML(more than 175 m) was found in the region of(22?–30?S, 105?–90?W), reaching its maximum depth(~200 m) near(27?–28?S, 100?W) in September. The relative importance of horizontal density advection in determining the maximum ML location is discussed qualitatively. Downward Ekman pumping is key to determining the eastern boundary of the deep ML region. In addition, zonal density advection by the subtropical countercurrent(STCC) in the subtropical Southwest Pacific determines its western boundary, by carrying lighter water to strengthen the stratification and form a 'shallow tongue' of ML depth to block the westward extension of the deep ML in the STCC region. The temperature advection by the STCC is the main source for large heat loss from the subtropical Southwest Pacific. Finally, the combined effect of net surface heat flux and meridional density advection by the subtropical gyre determines the northern and southern boundaries of the deep ML region: the ocean heat loss at the surface gradually increases from 22?S to 35?S, while the meridional density advection by the subtropical gyre strengthens the stratification south of the maximum ML depth and weakens the stratification to the north. The freshwater flux contribution to deepening the ML during austral winter is limited. The results are useful for understanding the role of ocean dynamics in the ML formation in the subtropical Southeast Pacific. | Qinyu LIU Yiqun LU | 2016 | Advances in Atmospheric Sciences2016，33，4： | 3 |
| 10 | Atmospheric gaseous organic acids in winter in a rural site of the North China Plain显示文摘Organic acids are important contributors to the acidity of atmospheric precipitation,but their existence in the Chinese atmosphere is largely unclear.In this study,twelve atmospheric gaseous organic acids,including C_(1)-C_(9) alkanoic acids,methacrylic acid,pyruvic acid,and benzoic acid,were observed in the suburb of Wangdu,Hebei Province,a typical rural site in the northern China plain from 16^(th) December,2018 to 22^(nd) January,2019,using a Vocus■ Proton-Transfer-Reaction time-of-flight mass spectrometer(Vocus PTR-ToF).The quantification of C_(2)-C_(4) alkanoic acids by the Vocus PTR-ToF was calibrated according to the titration of a NaOH solution by C_(2)-C_(4) alkanoic acids from home-made permeation sources,and the other organic acids except for formic acid were quantified based on the k_(cap)-sensitivity linearity in the Vocus PTR-ToF,whereas formic acid was not quantified because our instrument setting led to a significant underestimation in its concentration.The average total concentration of eleven gaseous organic acids was 6.96±5.20 ppbv(parts per billion by volume).The average concentration of acetic acid was the highest(3.86±3.00 ppbv),followed by propanoic acid,butyric acid,and methacrylic acid.Domestic straw burning was likely the dominant source of the observed gaseous organic acids according to the good correlations between acetonitrile and organic acids and between particulate K+and organic acids,and traffic emissions could also have contributed.During episodes with continuously high concentrations of organic acids,short-distance transport dominated in Wangdu according to the backward trajectory analysis.Baoding,Shijiazhuang,and Hengshui areas were the main source areas based on potential source contribution function and concentration weighing track analysis. | Xiaoyu Hu Gan Yang Yiliang Liu Yiqun Lu Yuwei Wang Hui Chen Jianmin Chen Lin Wang | 2022 | Journal of Environmental Sciences2022，34，3： | 1 |
| 11 | Highly crystalline acceptor materials based on benzodithiophene with different amount of fluorine substitution on alkoxyphenyl conjugated side chains for organic photovoltaics显示文摘Organic solar cells based on narrow bandgap small-molecule acceptors(SMAs)with highly crystalline characteristics have attracted great attentions for their superiority in obtaining high photovoltaic efficiency.Employing highly crystalline SMAs to enhance power conversion efficiencies(PCEs)by regulating and controlling morphology and compatibility of donor and acceptor materials has turned out to be an effective approach.In this study,we synthesized three different crystalline SMAs by using fluorine substitution on alkoxyphenyl conjugated side chains to modulate the relationship of crystallinity and morphologies,namely ZY1(zero F atoms),ZY2(two F atoms),and ZY3(four F atoms).The three SMAs show the broad absorption edges and similar frontier orbital energy levels,generating the analogical(over 0.9 V)open circuit voltage(VOC)of the polymer solar cells(PSCs).As a result,the PM6:ZY2-based PSCs yield a PCE of 10.81%with a VOC of 0.95 V,a short-circuit current density(JSC)of 16.154 mA cm^(-2),and a fill factor(FF)of 0.71,which is higher than that of 9.17%(PM6:ZY1)and 6.37%(PM6:ZY3).And the PCE(17.23%)of the PM6:Y6:ZY2 based ternary PSCs is also higher than that of 16.32%PM6:Y6 based binary device.Obviously,the results demonstrate that adding fluorine atoms on the conjugated side chains to construct high crystalline materials is a positive strategy to effectively increase the efficiencies of binary and ternary PSCs. | Youdi Zhang Ruijie Ma Yong Wang Ying Wang Tao Liu Yiqun Xiao Yongjoon Cho Zhenghui Luo Xinhui Lu Lun Zhao Zhongyi Yuan Changduk Yang He Yan Yiwang Chen | 2021 | Materials Reports(Energy)2021，1，4： | 1 |
| 12 | Coupling efficiency of single-mode fiber compoments using GRIN-rod lenses 显示文摘 | Lu Yiqun Palais Joseph C | 1988 | Fiber and Integrated Opt1988，7，1： | 1 |
| 13 | UV-enhanced room temperature NO 2 sensor using ZnO nanorods modified with SnO 2 nanoparticles显示文摘 | Geyu Lu Jing Xu Jianbo Sun Yingshuo Yu Yiqun Zhang Fengmin Liu | 2011 | Sensors & Actuators: B. Chemical2011，，： | 1 |
| 14 | Effects of a dipole-like crustal field on solar wind interaction with Mars显示文摘A three-dimensional four species multi-fluid magnetohydrodynamic (MHD) model was constructed to simulate the solar wind global interaction with Mars. The model was augmented to consider production and loss of the significant ion species in the Martian ionosphere, i.e., H^+, O2^+, O^+, CO^+2, associated with chemical reactions among all species. An ideal dipole-like local crustal field model was used to simplify the empirically measured Martian crustal field. Results of this simulation suggest that the magnetic pile-up region (MPR) and the velocity profile in the meridian plane are asymmetric, which is due to the nature of the multi-fluid model to decouple individual ion velocity resulting in occurrence of plume flow in the northern Martian magnetotail. In the presence of dipole magnetic field model, boundary layers, such as bow shock (BS) and magnetic pile-up boundary (MPB), become protuberant. Moreover, the crustal field has an inhibiting effect on the flux of ions escaping from Mars, an effect that occurs primarily in the region between the terminator (SZA 90°) and the Sun Mars line of the magnetotail (SZA 180°), partially around the terminator region. In contrast, near the tailward central line the crustal field has no significant impact on the escaping flux. | ShiBang Li HaoYu Lu Jun Cui YiQun Yu Christian Mazelle Yun Li JinBin Cao | 2020 | Earth and Planetary Physics2020，4，1： | 0 |
| 15 | Covariability of Subantarctic Mode Water and the Southern Branch of the Subtropical Indian Ocean Countercurrent in Argo Observations显示文摘The Subantarctic Mode Water(SAMW)forms in the deep mixed layer north of the Antarctic Circumpolar Current and spreads northward into the subtropical gyre.The subtropical South Indian Countercurrent(SICC)flows eastward on the north flank of the thick SAMW layer within 22°-32°S from south of Madagascar at around 25°S,50°E toward western Australia.The dynamical relation of the SAMW and the southern branch of the SICC(30°-32°S)is investigated in this work based on the monthly mean Argo data from 2004 to 2019.The physical properties of the SAMW and its pathway from the formation region are described.Most of the SAMW in the Indian Ocean sector originates from the deep mixed layers of the southeastern Indian Ocean(about 40°S,85°-105°E)and moves along the subtropical gyre.It takes around ten years to arrive east of Madagascar Island preserving its low potential vor-ticity characteristics.As a thick layer with homogeneous vertical properties,the SAMW forces the upper pycnocline to shoal,and the associated eastward shear results in the surface-intensified SICC.The SAMW forms a tongue-shaped thickness pattern,which influ-ences the southern branch of the SICC above the northern flank of the thickest SAMW layer between 24°S and 32°S.The seasonal,interannual,and decade variations of the southern branch of the SICC are closely related to the meridional gradient of the underlying SAMW thickness.The SAMW thickened and strengthened from 2005 to 2015,thereby anchoring a strengthened SICC.The interan-nual covariability of the SAMW and SICC further supports the SAMW’s role in driving SICC variability. | LU Yiqun LIU Qinyu XIE Shang-Ping | 2021 | Journal of Ocean University of China2021，20，6： | 0 |
| 16 | Generation ofαGal-enhanced bifunctional tumor vaccine显示文摘Hepatocellular carcinoma(HCC)is a common malignant tumor with poor prognosis and high mortality.In this study,we demonstrated a novel vaccine targeting HCC and tumor neovascular endothelial cells by fusing recombinant MHCC97H cells expressing porcine a-1,3-galactose epitopes(a Gal)and endorphin extracellular domains(END)with dendritic cells(DCs)from healthy volunteers.END^(+)/Gal^(+)-MHCC97H/DC fusion cells induced cytotoxic T lymphocytes(CTLs)and secretion of interferon-gamma(IFN-γ).CTLs targeted cells expressing a Gal and END and tumor angiogenesis.The fused cell vaccine can effectively inhibit tumor growth and prolong the survival time of human hepatoma mice,indicating the high clinical potential of this new cell based vaccine. | Jian He Yu Huo Zhikun Zhang Yiqun Luo Xiuli Liu Qiaoying Chen Pan Wu Wei Shi Tao Wu Chao Tang Huixue Wang Lan Li Xiyu Liu Yong Huang Yongxiang Zhao Lu Gan Bing Wang Liping Zhong | 2022 | Acta Pharmaceutica Sinica B2022，12，7： | 0 |
| 17 | Generation of in situ CRISPR-mediated primary and metastatic cancer from monkey liver显示文摘Non-human primates(NHPs)represent the most valuable animals for drug discovery.However,the current main challenge remains that the NHP has not yet been used to develop an efficient translational medicine platform simulating human diseases,such as cancer.This study gen erated an in situ gen e-editi ng approach to in duce efficie nt loss-of-function mutations of Pten and p53 genes for rapid modeling primary and metastatic liver tumors using the CRISPR/Cas9 in the adult cyno molgus mon key.Un der ultraso und guida nee,the CRISPR/Cas9 was injected into the cyno molgus mon key liver through the in trahepatic portal vein.The results showed that the ultraso un d-guided CRISPR/Cas9 resulted in in dels of the Pten and p53 genes in seve n out of eight monkeys.The best mutation efficiencies for Pten and p53 were up to 74.71%and 74.68%,respectively.Furthermore,the morbidity of primary and exte nsively metastatic(lung,splee n,lymph nodes)hepatoma in CRISPR-treated mon keys was 87.5%.The ultraso un d-guided CRISPR system could have great potential to successfully pursue the desired target genes,thereby reducing possible side effects associated with hitting no n-specific off-target genes,and sign ifica ntly in creasing more efficie ncy as well as higher specificity of in situ gene editi ng in vivo,which holds promise as a powerful,yet feasible tool,to edit disease genes to build corresp on ding huma n disease models in adult NHPs and to greatly accelerate the discovery of new drugs and save economic costs. | Liping Zhong Yong Huang Jian He Nuo Yang Banghao Xu Yun Ma Junjie Liu Chao Tang Chengpiao Luo Pan Wu Zongqiang Lai Yu Huo Tao Lu Dongni Huang Wenlin Gong Lu Gan Yiqun Luo Zhikun Zhang Xiyu Liu Yongxiang Zhao | 2022 | Signal Transduction and Targeted Therapy2022，7，1： | 0 |
| 18 | Achieving 16.68% efficiency ternary as-cast organic solar cells显示文摘State-of-the-art organic solar cells(OSCs)often require the use of high-boiling point additive or post-treatment such as temperature annealing and solvent vapor annealing to achieve the best efficiency.However,additives are not desirable in largescale industrial printing process,while post-treatment also increases the production cost.In this article,we report highly efficient ternary OSCs based on PM6:BTP-Cl Br1:BTP-2O-4Cl-C12(weight ratio=1:1:0.2),with 16.68%power conversion efficiency(PCE)for as-cast device,relatively close to its annealed counterpart(17.19%).Apart from obvious energy tuning effect and complementary absorption spectra,the improved PCE of ternary device is mainly attributed to improved morphological properties including the more favorable materials miscibility,crystallinity,domain size and vertical phase separation,which endorse suppressed recombination.The result of this work provides understanding and guidance for high-performance as-cast OSCs through the ternary strategy. | Ruijie Ma Yang Tao Yuzhong Chen Tao Liu Zhenghui Luo Yuan Guo Yiqun Xiao Jin Fang Guangye Zhang Xiaojun Li Xia Guo Yuanping Yi Maojie Zhang Xinhui Lu Yongfang Li He Yan | 2021 | Science China Chemistry2021，64，4： | 0 |
| 19 | Air-Processed Efficient Organic Solar Cells from Aromatic Hydrocarbon Solvent without Solvent Additive or Post-Treatment:Insights into Solvent Effect on Morphology显示文摘Most of the recent organic solar cells(OSCs)with top-of-the-line efficiencies are processed from organic solvents with a high vapor pressure such as CF in nitrogen-filled glovebox,which is not feasible for large-area manufacturing.Herein,we cast active layers with both aromatic hydrocarbon solvents and halogenated solvents without any solvent additive or post-treatment,as well as interlayers with water and methanol in air(35%relative humidity)for efficient OSCs,except cathode electrode's evaporation is in vacuum.Compared to the PM6:Y6 system that is processed from CF,the PM6:BTP-ClBr2 system demonstrates good efficiency of 16.28%processed from CB and the device based on PM6:BTP-4Cl achieves 16.33%using TMB as its solvent for the active layer.These are among the highest efficiencies for CB-and TMB-processed binary OSCs to date.The molecular packing and phase separation length scales of each combination depend strongly on the solvent,and the overall morphology is the result of the interplay between solvent evaporation(kinetics)and materials miscibility(thermodynamics).Different solvents are required to realize the optimal morphology due to the different miscibility between the donor and acceptor.Finally,17.36%efficiency was achieved by incorporating PC71BM for TMB-processed devices.Our result provides insights into the effect of processing solvent and shows the potential of realizing high-performance OSCs in conditions relevant for industrial fabrication. | Ruijie Ma Tao Yang Yiqun Xiao Tao Liu Guangye Zhang Zhenghui Luo Gang Li Xinhui Lu He Yan Bo Tang | 2022 | Energy & Environmental Materials2022，5，3： | 0 |
| 20 | A recombinant Newcastle disease virus expressing MMP8 promotes oncolytic efficacy显示文摘Oncolytic virus is an emerging anti-cancer strategy. However, extracellular matrix(ECM), as a physical barrier, limits virus spread within the tumor. To overcome the obstacle, we constructed a recombinant Newcastle disease virus(NDV) expressing matrix metalloproteinase(MMP8)(NDV-MMP8) using with reverse genetic technology. In vitro, NDV-MMP8 was identified and verified by WB and ELISA. Cell viability was detected by CCK-8 assay. In vivo, we established two liver cancer xenograft models. NDV-MMP8 was injected into the tumor to observe the tumor volume and survival of mice. The changes in extracellular matrix were observed by Masson’s trichrome staining. Virus expression in tumor tissues was detected by immunofluorescence assay. The virus titer in tumor tissues was detected by TCID50. Histopathological changes were detected by hematoxylin and eosin(HE) and terminal deoxynucleotidyl transferase d UTP nick end labeling(TUNEL) staining. Intratumoral administration of NDV-MMP8 can effectively degrade ECM, promote the spread of the virus within the tumor, and reduce tumor growth rate. Therefore, the method of increasing intratumoral virus accumulation by degradation of the ECM to enhance the oncolytic effect has great potential for clinical application. | Tong Guo Xiuli Liu Zhikun Zhang Yiqun Luo Tong Li Lan Li Huixue Wang Yong Huang Jian He Qiaoying Chen Yongxiang Zhao Lu Gan Liping Zhong | 2021 | Chinese Chemical Letters2021，32，12： | 0 |
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