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| 1 | BMP-6 inhibits microRNA-21 expression in breast cancer through repressing 6EF1 and AP-1显示文摘 | Jun Du Shuang Yang Di An Fen Hu Wei Yuan Chunli Zhai Tianhui Zhu | 2009 | Cell Research2009,19,4: | 44 |
| 2 | miR-223 and miR-142 attenuate hematopoietic cell proliferation, and miR-223 positively regulates miR-142 through LMO2 isoforms and CEBP-β显示文摘miR-142 和 miR-223 作为造血的特定的 microRNAs 被识别了。miR-223 在 myeloid 系开发有关键功能。然而, miR-142 的功能仍然保持不清楚。在这研究,我们发现那 miR-142, miR-223 稀释了造血的房间,和那 miR-223 的增长通过 LMO2-L/-S isoforms 和 CEBP- 尾的起来调整的 miR-142 表示。miR-223 否定地 post-transcriptionally 调整了 LMO2-L/-S isoforms 和 CEBP- 尾,当 CEBP- 尾断然调整了 LMO2-L/-S isoforms 并且否定地两个都 LMO2-L/-S isoforms 调整了 miR-142 时。这些结果揭示一条新奇 miR-223 鈥擟E BP-尾鈥擫M O2 鈥攎i R-142 规章的小径,它在造血作用有枢轴的功能。 | Wei Sun Wenwen Shen Shuang Yang Fen Hu Huihui Li Tian-Hui Zhu | 2010 | Cell Research2010,20,10: | 12 |
| 3 | Progress in improving thermodynamics and kinetics of new hydrogen storage materials显示文摘 | Li-fang SONG Chun-hong JIANG Shu-sheng LIU Cheng-li JIAO Xiao-liang SI Shuang WANG Fen LI Jian ZHANG Li-xian SUN Fen XU Feng-lei HUANG | 2011 | Frontiers of physics2011,6,2: | 3 |
| 4 | Atomic-layer-deposited (ALD) Al2O3passivation dependent interface chemistry, band alignment and electrical properties of HfYO/Si gate stacks显示文摘In this work, the effects of atomic-layer-deposited(ALD) Al2O3 passivation layers with different thicknesses on the interface chemistry and electrical properties of sputtering-derived HfYO gate dielectrics on Si substrates have been investigated. The results of electrical measurements and X-ray photoelectron sepectroscopy(XPS) showed that 1-nm-thick Al2O3 passivation layer is optimized to obtain excellent electrical and interfacial properties for HfYO/Si gate stack. Then, the metal-oxide-semiconductor capacitors with HfYO/1-nm Al2O3/Si/Al gate stack were fabricated and annealed at different temperatures in forming gas(95% N2+5% H2). Capacitance-voltage(C-V) and current density-voltage(J-V) characteristics showed that the 250℃-annealed HYO high-k gate dielectric thin film demonstrated the lowest border trapped oxide charge density(-3.3 × 1010 cm-2), smallest gate-leakage current(2.45 × 10-6 A/cm2 at 2 V)compared with other samples. Moreover, the annealing temperature dependent leakage current conduction mechanism for Al/HfYO/Al2O3/Si/Al MOS capacitor has been investigated systematically. Detailed electrical measurements reveal that Poole-Frenkle emission is the main dominant emission in the region of low and medium electric fields while direct tunneling is dominant conduction mechanism at high electric fields. | Shuang Liang Gang He Die Wang Fen Qiao | 2019 | Journal of Materials Science & Technology2019,35,5: | 1 |
| 5 | Power and thermal aware mapping for 3D network-on-chip 显示文摘 | Ge Fen Feng Gui Yu Shuang | 2013 | Information Technology Journal2013,12,23: | 1 |
| 6 | An efficient synthesis of 3,4-dihydropyrimidin-2-ones catalyzed by NH2 SOs H under ultrasound irradiation显示文摘 | LI Ji Tai HAN Jun Fen LI Tong Shuang | 2003 | Ultrason Sonochem2003,10,3: | 1 |
| 7 | Dexamethasone potentiates the insulin-induced Srebp-1c expression in primary rat hepatocytes显示文摘The impacts of dexamethasone(Dex)and thyroid hormone T3 on the insulin-stimulated Srebp-1c expression were studied in primary rat hepatocytes. Primary hepatocytes from Sprague-Dawley rats were isolated, cultured and treated with insulin in the presence or absence of the indicated reagents over time. The mRNA levels of indicated genes were determined using real-time PCR. Insulin treatment induced the Srebp-1c expression and suppressed the Pck1 expression in a time-dependent manner. Dex treatment alone reduced the Srebp-1c expression, whereas potentiated the insulin-induced its expression, which reached to a level that was higher than the insulin alone group. On the other hand, insulin treatment completely suppressed the Dex-induced Pck1 expression in the same cells. T3 treatment did not affect the expressions of Srebp-1c and Pck1 alone or in the presence of absence of insulin or Dex. Interestingly, insulin treatment induced the Rxrg m RNA expression level in the absence or presence of T0901317, a specific agonist for the liver X receptor. Dex and insulin mutually affect each other's ability to regulate the expression levels of hepatic genes involved in glucose and fatty acid metabolism. Insulin induced Rxrg expression in primary hepatocytes, which may contribute to the induction of Srebp-1c expression in the same cells. | Yan Zhang Xiangming Fang Fen Shuang Guoxun Chen | 2023 | Food Science and Human Wellness2023,12,5: | 0 |
| 8 | Prediction of Renal Function by Urinary Lead and Cadmium - Based on Classification Decision Tree and Logistic Regression Model显示文摘It is estimated that chronic kidney disease(CKD)will be the fifth leading cause of death in the world by 2040[1].Early recognition and intervention for kidney damage are essential.Estimated glomerular filtration rate(eGFR)can be calculated by measuring blood creatinine to evaluate glomerular function,and urinary N-acetyl-β-δ-glucosaminidase(UNAG)level is generally recognized as a marker of renal tubular injury.Exposure to lead(Pb)and cadmium(Cd)can damage renal function,leading to a decrease in eGFR and an increase in UNAG[2].Both Pb and Cd are easily accumulated in the body and then slowly released by the kidneys and excreted.So,urinary Pb(UPb)and Cd(UCd)levels can be used as biomarkers of exposure[3,4]. | LI Yang WANG Qing Yao TIAN Qing Hua AN Qi YANG Yu Tong ZHANG Jia Chen LI Shuang Jing ZHOU Han LIANG Yun Fen SHEN Wei Tong MU Li Na LEI Li Jian | 2024 | Biomedical and Environmental Sciences2024,37,3: | 0 |
| 9 | A novel carbazole-based fluorescent probe:3,6-Bis-[(N-ethylcarbazole-3-y1)-propene-1-keto]-N-ethylcarbazole显示文摘A novel carbazole-based compound 5,3,6-bis[(N-ethylcarbazole-3-yl)-propene-1-keto]-N-ethylcarbazole has been designed, synthesized and characterized.The absorption and fluorescence spectra in solvents of different polarities prove that the compound has a distinct intramolecular charge transfer character.Compound 5 can be used as a new class of fluorescent probe or biosensor due to its sensitivity to the local microenvironment such as solvent polarity. | Hao, Li Ling Li, Jun Fen Lin, Pei Hua Dong, Rui Feng Li, Du Xin Shuang, Shao Min Dong, Chuan | 2010 | Chinese Chemical Letters2010,21,1: | 0 |