|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Integrated study of the water–ecosystem–economy in the Heihe River Basin显示文摘The ecological water diversion project in the Heihe River Basin is the irst successful case in China in which the ecological systems in a river basin have been rescued. his project serves as a valuable example for the management of ecosystems in other inland river basins. his paper reviews the integrated studies of the water–ecosystem–economy relationship in the Heihe River Basin and concludes that sustainable development in inland river basins requires the basin to be considered as a whole, with the relationships between the upstream, midstream and downstream areas of the basin coordinated appropriately. Successful development in these basins will be relected in an improved output per cubic meter of water and the implementation of integrated river basin management practices. | Guodong Cheng Xin Li Wenzhi Zhao Zhongmin Xu Qi Feng Shengchun Xiao Honglang Xiao | 2014 | National Science Review2014，1，3： | 55 |
| 2 | A survey on applications of semi-tensor product method in engineering显示文摘Semi-tensor product(STP) of matrices has attracted more and more attention from both control theory and engineering in the last two decades. This paper presents a comprehensive survey on the applications of STP method in engineering. Firstly, some preliminary results on STP method are recalled.Secondly, some applications of STP method in engineering, including gene regulation, power system, wireless communication, smart grid, information security, combustion engine and vehicle control, are reviewed.Finally, some potential applications of STP method are predicted. | Haitao LI Guodong ZHAO Min MENG June FENG | 2018 | Science China(Information Sciences)2018，61，1： | 12 |
| 3 | Hydrothermal Synthesis of Molybdenum Disulfide for Lithium Ion Battery Applications显示文摘Molybdenum disulfide nanoflakes were synthesized by a simple hydrothermal process using sodium molybdate and thiourea as reactants at a relatively low temperature. X-ray diffraction(XRD) and transmission elec-tron microscopy(TEM) indicate that the samples have the structure of 2H-MoS2 and the morphology of nanoflakes with the average thickness around 5-10 nm. The results of electrochemical properties indicate that the morphology and size of MoS2 particles have effects on their capacity when they are used as the anode for lithium ion battery. The as-prepared MoS2 samples have high reversible discharge capacity up to 994.6 mA·h·g-1 for the MoS2-1 elec-trode and 930.1 mA·h·g-1 for the MoS2-2 electrode and show excellent cycling performances. The MoS2-1 electrode has a better cycling stability than the MoS2-2 electrode due to their difference in the uniformity of the samples. | WANG Shiquan LI Guohua DU Guodong JIANG Xueya FENG Chuanqi GUO Zaiping KIM Seung-Joo | 2010 | Chinese Journal of Chemical Engineering2010，18，6： | 9 |
| 4 | Genome sequencing and phylogenetic analysis of Banna virus(genus Seadornavirus,family Reoviridae)isolated from Culicoides显示文摘In an investigation of blood-sucking insects and arboviruses, a virus(YN12243) was isolated from Culicoides samples collected in the Sino-Burmese border region of Yunnan Province, China. The virus caused cytopathic effect(CPE) in C6/36 cells and passaged stably. Polyacrylamide gel analysis showed that the genome of YN12243 was composed of 12 segments of double-stranded RNA(dsRNA), with a distribution pattern of 6-6. The nucleotide and amino acid sequences of the coding region(1.12 segments) were17,803 bp and 5,925 amino acids in length, respectively. The phylogenetic analysis of VP1 protein(RdRp) revealed that YN12243 belonged to genus Seadornavirus of family Reoviridae, and further analysis indicated that YN12243 belongs to the Banna virus(BAV) genotype A2. Additionally, YN12243 was located in the same evolutionary cluster as BAV strains isolated from different mosquito species, suggesting that the BAV isolated from Culicoides does not have species barriers. These results indicate that Culicoides can also be a vector for BAV. In view of the hematophagous habits of Culicoides on cattle, horses, deer, and other large animals, as well as the possibility of spreading and causing a variety of animal arboviral diseases, it is important to improve infection detection and monitor the BAV in large livestock. | Song Song Yuanyuan Li Shihong Fu Wenwen Lei Xiaofang Guo Yun Feng Xiaoyan Gao Xiaolong Li Zhonghua Yang Ziqian Xu Ying He Huanyu Wang Hongning Zhou Bin Wang Xiaoqing Lu Guodong Liang | 2017 | Science China(Life Sciences)2017，60，12： | 8 |
| 5 | Antagonism of Protease-Activated Receptor 4 Protects Against Traumatic Brain Injury by Suppressing Neuroinflammation via Inhibition of Tab2/NF-κB Signaling显示文摘Traumatic brain injury(TBI)triggers the activation of the endogenous coagulation mechanism,and a large amount of thrombin is released to curb uncontrollable bleeding through thrombin receptors,also known as protease-activated receptors(PARs).However,thrombin is one of the most critical factors in secondary brain injury.Thus,the PARs may be effective targets against hemorrhagic brain injury.Since the PAR1 antagonist has an increased bleeding risk in clinical practice,PAR4 blockade has been suggested as a more promising treatment.Here,we explored the expression pattern of PAR4 in the brain of mice after TBI,and explored the effect and possible mechanism of BMS-986120(BMS),a novel selective and reversible PAR4 antagonist on secondary brain injury.Treatment with BMS protected against TBI in mice.mRNA-seq analysis,Western blot,and qRT-PCR verification in vitro showed that BMS significantly inhibited thrombin-induced inflammation in astrocytes,and suggested that the Tab2/ERK/NF-κB signaling pathway plays a key role in this process.Our findings provide reliable evidence that blocking PAR4 is a safe and effective intervention for TBI,and suggest that BMS has a potential clinical application in the management of TBI. | Jianing Luo Xun Wu Haixiao Liu Wenxing Cui Wei Guo Kang Guo Hao Guo Kai Tao Fei Li Yingwu Shi Dayun Feng Hao Yan Guodong Gao Yan Qu | 2021 | Neuroscience Bulletin2021，37，2： | 5 |
| 6 | Chinese expert consensus on programming deep brain stimulation for patients with Parkinson’s disease显示文摘Background:Deep Brain Stimulation(DBS)therapy for the treatment of Parkinson’s Disease(PD)is now a well-established option for some patients.Postoperative standardized programming processes can improve the level of postoperative management and programming,relieve symptoms and improve quality of life.Main body:In order to improve the quality of the programming,the experts on DBS and PD in neurology and neurosurgery in China reviewed the relevant literatures and combined their own experiences and developed this expert consensus on the programming of deep brain stimulation in patients with PD in China.Conclusion:This Chinese expert consensus on postoperative programming can standardize and improve postoperative management and programming of DBS for PD. | Shengdi Chen Guodong Gao Tao Feng Jianguo Zhang The Chinese Medical Association neurosurgery branch of functional neurosurgery group The Chinese Medical Association neurology branch of Parkinson’s disease,Movement disorders group The Chinese Physician Association neurosurgeon branch of functional neurosurgery expert committee The Chinese Physician Association neurologist branch of Parkinson’s disease and Movement disorders professional committee Chinese expert committee on Deep Brain Stimulation for Parkinson’s Disease | 2018 | Translational Neurodegeneration2018，7，1： | 5 |
| 7 | Temperature-induced Lifshitz transition in topological insulator candidate HfTe_5显示文摘The ongoing discoveries and studies of novel topological quantum materials have become an emergent and important field of condensed matter physics.Recently,HfTe_5 ignited renewed interest as a candidate of a novel topological material.The single-layer HfTe_5 is predicted to be a two-dimensional large band gap topological insulator and can be stacked into a bulk that may host a temperature-driven topological phase transition.Historically,HfTe_5 attracted considerable interest for its anomalous transport properties characterized by a peculiar resistivity peak accompanied by a sign reversal carrier type.The origin of the transport anomaly remains under a hot debate.Here we report the first high-resolution laser-based angle-resolved photoemission measurements on the temperature-dependent electronic structure in HfTe_5.Our results indicated that a temperature-induced Lifshitz transition occurs in HfTe_5,which provides a natural understanding on the origin of the transport anomaly in HfTe_5.In addition,our observations suggest that HfTe_5 is a weak topological insulator that is located at the phase boundary between weak and strong topological insulators at very low temperature. | Yan Zhang Chenlu Wang Guodong Liu Aiji Liang Lingxiao Zhao Jianwei Huang Qiang Gao Bing Shen Jing Liu Cheng Hu Wenjuan Zhao Genfu Chen Xiaowen Jia Li Yu Lin Zhao Shaolong He Fengfeng Zhang Shenjin Zhang Feng Yang Zhimin Wang Qinjun Peng Zuyan Xu Chuangtian Chen Xingjiang Zhou | 2017 | Science Bulletin2017，62，13： | 4 |
| 8 | Exosomal PD-L1 induces osteogenic differentiation and promotes fracture healing by acting as an immunosuppressant显示文摘A moderate inflammatory response at the early stages of fracture healing is necessary for callus formation.Over-active and continuous inflammation,however,impairs fracture healing and leads to excessive tissue damage.Adequate fracture healing could be promoted through suppression of local over-active immune cells in the fracture site.In the present study,we achieved an enriched concentration of PD-L1 from exosomes(Exos)of a genetically engineered Human Umbilical Vein Endothelial Cell(HUVECs),and demonstrated that exosomes overexpressing PD-L1 specifically bind to PD-1 on the T cell surface,suppressing the activation of T cells.Furthermore,exosomal PD-L1 induced Mesenchymal Stem Cells(MSCs)towards osteogenic differentiation when pre-cultured with T cells.Moreover,embedding of Exos into an injectable hydrogel allowed Exos delivery to the surrounding microenvironment in a time-released manner.Additionally,exosomal PD-L1,embedded in a hydrogel,markedly promoted callus formation and fracture healing in a murine model at the early over-active inflammation phase.Importantly,our results suggested that activation of T cells in the peripheral lymphatic tissues was inhibited after local administration of PD-L1-enriched Exos to the fracture sites,while T cells in distant immune organs such as the spleen were not affected.In summary,this study provides the first example of using PD-L1-enriched Exos for bone fracture repair,and highlights the potential of Hydrogel@Exos systems for bone fracture therapy through immune inhibitory effects. | Ze Lin Yuan Xiong Weilin Meng Yiqiang Hu Lili Chen Lang Chen Hang Xue Adriana CPanayi Wu Zhou Yun Sun Faqi Cao Guodong Liu Liangcong Hu Chenchen Yan Xudong Xie Chuanchuan Lin Kaiyong Cai Qian Feng Bobin Mi Guohui Liu | 2022 | Bioactive Materials2022，7，7： | 4 |
| 9 | Advances in diagnosis and non-surgical treatment of Bell's palsy显示文摘Bell's palsy is a commonly seen cranial nerve disease and can result in compromised facial appearance and functions. Its etiology, prognosis and treatment are still being debated. This paper is a review of recent development in the understanding of etiology, diagnosis and non-surgical treatment of Bell's palsy. | Yang Zhao Guodong Feng Zhiqiang Gao | 2015 | Journal of Otology2015，10，1： | 3 |
| 10 | Inhibition of the CDK9-cyclin T1 protein-protein interaction as a new approach against triple-negative breast cancer显示文摘Cyclin-dependent kinase 9(CDK9) activity is correlated with worse outcomes of triplenegative breast cancer(TNBC) patients. The heterodimer between CDK9 with cyclin T1 is essential for maintaining the active state of the kinase and targeting this protein-protein interaction(PPI) may offer promising avenues for selective CDK9 inhibition. Herein, we designed and generated a library of metal complexes bearing the 7-chloro-2-phenylquinoline CN ligand and tested their activity against the CDK9cyclin T1 PPI. Complex 1 bound to CDK9 via an enthalpically-driven binding mode, leading to disruption of the CDK9-cyclin T1 interaction in vitro and in cellulo. Importantly, complex 1 showed promising anti-metastatic activity against TNBC allografts in mice and was comparably active compared to cisplatin. To our knowledge, 1 is the first CDK9-cyclin T1 PPI inhibitor with anti-metastatic activity against TNBC. Complex 1 could serve as a new platform for the future design of more efficacious kinase inhibitors against cancer, including TNBC. | Sha-Sha Cheng Yuan-Qing Qu Jia Wu Guan-Jun Yang Hao Liu Wanhe Wang Qi Huang Feng Chen Guodong Li Chun-Yuen Wong Vincent Kam Wai Wong Dik-Lung Ma Chung-Hang Leung | 2022 | Acta Pharmaceutica Sinica B2022，12，3： | 2 |
| 11 | Variations in dry soil and respective ecosystems of sandy land in China显示文摘 | Feng Qi Cheng Guodong Endo Kunihiko | 2001 | Environmental Geology2001，40，9： | 2 |
| 12 | Soil carbon in desertifled land in relation to site characteristics 显示文摘 | Feng Q Endo K N Guodong C | 2002 | Geoder- ma2002，106，1： | 1 |
| 13 | Variations in dry soil and respective ecosystems of sandy land in China显示文摘 | Feng Qi Cheng Guodong Endo Kunihiko | 2001 | Environmental Geology2001，40，9： | 1 |
| 14 | Soil carbon in desertified land in relation to site charaeteristics显示文摘 | Feng Q Endo K Guodong C | 2002 | Geoderma2002，106，12： | 1 |
| 15 | Emergence of superconductivity from fully incoherent normal state in an iron-based superconductor (Ba_(0.6)K_(0.4))Fe_2As_2显示文摘In unconventional superconductors, it is generally believed that understanding the physical properties of the normal state is a pre-requisite for understanding the superconductivity mechanism. In conventional superconductors like niobium or lead, the normal state is a Fermi liquid with a well-defined Fermi surface and well-defined quasipartcles along the Fermi surface. Superconductivity is realized in this case by the Fermi surface instability in the superconducting state and the formation and condensation of the electron pairs(Cooper pairing). The high temperature cuprate superconductors, on the other hand, represent another extreme case that superconductivity can be realized in the underdoped region where there is neither well-defined Fermi surface due to the pseudogap formation nor quasiparticles near the antinodal regions in the normal state. Here we report a novel scenario that superconductivity is realized in a system with well-defined Fermi surface but without quasiparticles along the Fermi surface in the normal state.High resolution laser-based angle-resolved photoemission measurements have been performed on an optimally-doped iron-based superconductor(Ba_(0.6)K_(0.4))Fe_2As_2. We find that, while sharp superconducting coherence peaks emerge in the superconducting state on the hole-like Fermi surface sheets, no quasiparticle peak is present in the normal state. Its electronic behaviours deviate strongly from a Fermi liquid system. The superconducting gap of such a system exhibits an unusual temperature dependence that it is nearly a constant in the superconducting state and abruptly closes at Tc. These observations have provided a new platform to study unconventional superconductivity in a non-Fermi liquid system. | Jianwei Huang Lin Zhao Cong Li Qiang Gao Jing Liu Yong Hu Yu Xu Yongqing Cai Dingsong Wu Ying Ding Cheng Hu Huaxue Zhou Xiaoli Dong Guodong Liu Qingyan Wang Shenjin Zhang Zhimin Wang Fengfeng Zhang Feng Yang Qinjun Peng Zuyan Xu Chuangtian Chen Xingjiang Zhou | 2019 | Science Bulletin2019，64，1： | 1 |
| 16 | tuberculosis incerebrospinal fluidi显示文摘 | CHEN Ping SHI Ming FENG Guodong et aLA highly efficientZiehl-Neelsen stain : identifying de novo intracellular Mycobacteriumtuberculosis and improving detection of extracellular M | 2012 | J Clin Microbiol2012，50，4： | 1 |
| 17 | Diagnostic Accuracy ofIntrellular Mycobacterium tuberculosis Detection for TuberculousMeningitis显示文摘 | FENG Guodong SHI Ming MA Lei | 2014 | Am J Respir Crit Care Med2014，189，4： | 1 |
| 18 | Trends of water resource development and utilization in arid north-west China显示文摘 | Feng Qi Cheng Guodong Masao M K | 2000 | Environment Geology2000，39，8： | 1 |
| 19 | W-band GaN MMIC PA with 257 mW output power at 86.5 GHz Project supported by the National Natural Science Foundation of China (No. 61306113).显示文摘 | Xu Peng Song Xubo Lü Yuanjie Wang Yuangang Dun Shaobo Yin Jiayun Fang Yulong Gu Guodong Feng Zhihong Cai Shujun | 2015 | Journal of Semiconductors2015，，8： | 1 |
| 20 | Towards sustainable development of the environmentally degraded river Heihe basin,China显示文摘 | Feng Qi Cheng Guodong Kunihiko E | 2002 | Hydrological Science Journal-Journal Des Sciences Hydrologiques2002，46，5： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员