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| 1 | Construction of a Genome-Wide Mutant Library in Rice Using CRISPR/Cas9显示文摘 | Meng, Xiangbing Yu, Hong Zhang, Yi Zhuang, Fengfeng Song, Xiaoguang Gao, Songsong Gao, Caixia Li, Jiayang | 2017 | Molecular Plant2017，10，9： | 46 |
| 2 | Branched tetraether lipids in Chinese soils:Evaluating the fidelity of MBT/CBT proxies as paleoenvironmental proxies显示文摘The ubiquitous occurrence of branched glycerol dialkyl glycerol tetraethers(br GDGTs) in soils has allowed development of new proxies for reconstruction of past climate and environment. The methylation and cyclization degrees of br GDGTs, expressed as MBT and CBT, respectively, are reported to be mainly controlled by mean annual air temperature(MAAT) and soil p H. However, the br GDGT-derived temperatures and soil p H scatter widely when data from different environmental conditions are considered. In this study, we collected over 300 soil samples from China, which are representative of humid(Xishuangbanna, Guangzhou, and Shanghai), semi-arid(Dongying) and semi-arid/arid(Lanzhou, Tibetan Plateau) regions. Collectively we have the most extensive dataset that broadly characterizes the distribution of br GDGTs according to climate zones in China. The overall data demonstrate that the MBT/CBT derived temperatures better match the measured MAATs in humid and non-alkaline regions than those from regions of low MAP(<400 mm/yr) and above neutral soil p H(>7.0–7.5). Similarly, CBT describes soil p H much better in humid and non-alkaline soils than in semi-arid/arid and alkaline soils; the semi-arid/arid and alkaline soils tend to show a positive correlation between soil p H and CBT, which contradicts that in the humid and non-alkaline soils. While soil p H, MAAT and mean annual precipitation(MAP) are dominating factors controlling the br GDGT distribution across all climate zones, conductivity, total organic carbon and total nitrogen, as well as soil water content can also play an important role locally. Removing br GDGT-II resulted in a revised CBT index that provides more accurate estimation of p H, especially in semi-arid/arid and alkaline soils. The overall Chinese dataset demonstrates that continental air temperature derived from br GDGT-proxies can vastly deviate from real measurements and should be used with extreme caution in paleo-climate or-environment studies. | ZHENG FengFeng ZHANG ChuanLun CHEN YuFei LI FuYan MA CenLing PU Yang ZHU YuanQing WANG YongLi LIU WeiGuo | 2016 | Science China Earth Sciences2016，59，7： | 10 |
| 3 | Resequencing of 145 Landmark Cultivars Reveals Asymmetric Sub-genome Selection and Strong Founder Genotype Effects on Wheat Breeding in China显示文摘Controlled pedigrees and the multi-decade timescale of national crop plant breeding programs offer a unique experimental context for examining how selection affects plant genomes.More than 3000 wheat cultivars have been registered,released,and documented since 1949 in China.In this study,a set of 145 elite cultivars selected from historical points of wheat breeding in China were re-sequenced.A total of 43.75 Tb of sequence data were generated with an average read depth of 17.94x for each cultivar,and more than 60.92 million SNPs and 2.54 million InDels were captured,based on the Chinese Spring RefSeq genome v1.0.Seventy years of breeder-driven selection led to dramatic changes in grain yield and related phenotypes,with distinct genomic regions and phenotypes tar-geted by different breeders across the decades.There are very clear instances illustrating how introduced Italian and otherforeign germplasm was integrated into Chinese wheat programs and reshaped the genomic landscape of local modern cultivars.Importantly,the resequencing data also highlighted significant asymmetric breeding selec-tion among the three sub-genomes:this was evident in both the collinear blocks for homeologous chromosomes and among sets of three homeologous genes.Accumulation of more newly assembled genes in newer cultivars implied the potential value of these genes in breeding.Conserved and extended sharing of linkage disequilibrium(LD)blocks was highlighted among pedigree-related cultivars,in which fewer haplotype differences were detected.Fixation or replacement of haplotypes from founder genotypes after generations of breeding was related to their breeding value.Based on the haplotype frequency changes in LD blocks of pedigree-related cultivars,we propose a strategy for evaluating the breeding value of any given line on the basis of the accumulation(pyramiding)of bene-ficial haplotypes.Collectively,our study demonstrates the influence of 'founder genotypes' on the output of breeding efforts over many decades and also suggests that founder genotype perspectives are in fact more dy-namic when applied in the context of modern genomics-informed breeding. | Chenyang Hao Chengzhi Jiao Jian Hou Tian Li Hongxia Liu Yuquan Wang Jun Zheng Hong Liu Zhihong Bi Fengfeng Xu Jing Zhao Lin Ma Yamei Wang Uzma Majeed Xu Liu Rudi Appels Marco Maccaferri Roberto Tuberosa Hongfeng Lu Xueyong Zhang | 2020 | Molecular Plant2020，13，12： | 9 |
| 4 | Development of a new ferulic acid certified reference material for use in clinical chemistry and pharmaceutical analysis显示文摘This study compares the results of three certified methods,namely differential scanning calorimetry(DSC),the mass balance(MB) method and coulometric titrimetry(CT),in the purity assessment of ferulic acid certified reference material(CRM).Purity and expanded uncertainty as determined by the three methods were respectively 99.81%,0.16%;99.79%,0.16%;and 99.81%,0.26%with,in all cases,a coverage factor(k) of 2(P ? 95%).The purity results are consistent indicating that the combination of DSC,the MB method and CT provides a confident assessment of the purity of suitable CRMs like ferulic acid. | Dezhi Yang Fengfeng Wang Li Zhang Ningbo Gong Yang Lv | 2015 | Acta Pharmaceutica Sinica B2015，5，3： | 4 |
| 5 | Temperature-induced Lifshitz transition in topological insulator candidate HfTe_5显示文摘The ongoing discoveries and studies of novel topological quantum materials have become an emergent and important field of condensed matter physics.Recently,HfTe_5 ignited renewed interest as a candidate of a novel topological material.The single-layer HfTe_5 is predicted to be a two-dimensional large band gap topological insulator and can be stacked into a bulk that may host a temperature-driven topological phase transition.Historically,HfTe_5 attracted considerable interest for its anomalous transport properties characterized by a peculiar resistivity peak accompanied by a sign reversal carrier type.The origin of the transport anomaly remains under a hot debate.Here we report the first high-resolution laser-based angle-resolved photoemission measurements on the temperature-dependent electronic structure in HfTe_5.Our results indicated that a temperature-induced Lifshitz transition occurs in HfTe_5,which provides a natural understanding on the origin of the transport anomaly in HfTe_5.In addition,our observations suggest that HfTe_5 is a weak topological insulator that is located at the phase boundary between weak and strong topological insulators at very low temperature. | Yan Zhang Chenlu Wang Guodong Liu Aiji Liang Lingxiao Zhao Jianwei Huang Qiang Gao Bing Shen Jing Liu Cheng Hu Wenjuan Zhao Genfu Chen Xiaowen Jia Li Yu Lin Zhao Shaolong He Fengfeng Zhang Shenjin Zhang Feng Yang Zhimin Wang Qinjun Peng Zuyan Xu Chuangtian Chen Xingjiang Zhou | 2017 | Science Bulletin2017，62，13： | 4 |
| 6 | Glass fiber supported BiOI thin-film fixed-bed photocatalytic reactor for water decontamination under solar light irradiation显示文摘BiOI powder has been proved to be an efficient photocatalyst, but the difficulty in removing it from water after reaction limits its application in real water treatment. To solve this problem,a thin-film fixed-bed reactor(TFFBR) was set-up by developing a BiOI thin film on glass fiber cloth(GFC). The composition and structure of the as-prepared films were characterized with X-ray diffraction, X-ray photoelectron spectroscopy, field emission microscopy, transmission electron microscopy and Fourier transform infrared spectroscopy. The BiOI thin film was made by painting a silica sol containing BiOI on GFC, which could be tailored to desired sizes to accommodate the TFFBR. The mass of BiOI on the GFC increased with the number of iterations of the painting process. SiO2 sol glued the BiOI particles tightly onto the GFC,making the thin film strong enough to resist fluid flushing in the TFFBR. The photocatalytic activity of the BiOI thin film was investigated by degrading bisphenol A(BPA) under simulated sunlight. Ninety eight percent of BPA(20 mg/L in 2 L) was degraded by the BiOI thin film sample of seven layers(GFC-7) on the TFFBR within 8 hr irradiation. The GFC-7 displayed good photocatalytic ability toward artificial sewage containing BPA in a wide pH range(5–9),and also demonstrated excellent durability and reusability. The working conditions were optimized and it was found that the thickness of the fluid film and residence time over the thin film were key factors affecting the photocatalytic efficiency. | Yonghua Zhang Guoqiang Shan Fengfeng Dong Chenshuai Wang Lingyan Zhu | 2019 | Journal of Environmental Sciences2019，31，6： | 2 |
| 7 | Sol-gel preparation and phosphorescence property of Mn^(2+)-doped zinc boro-silicate glass thin films显示文摘Mn2+-doped zinc borosilicate (ZBSM) glass thin films were first synthesized by sol-gel method. In the experiment, a thin gel film was depos-ited onto quartz glass substrates by dip-coating method and then heat-treated to form a Mn2+-doped zinc borosilicate glass thin film. Long lasting phosphorescence (LLP) and photo-stimulated long lasting phosphorescence (PSLLP) were found in the film sample. According to fluorescence spectra, LLP emission spectra, and PSLLP emission spectra, both LLP and PSLLP emissions are attributed to the energy level transition of 4Eg→4A1g from Mn2+. Both the phosphorescence intensity decay curves contain a fast decay component and another slow decay one. The thermoluminescence (TL) spectra show that the sample has two kinds of traps at least and their energy level values are about 0.8 eV and 1.02 eV, which could be estimated by the Randall and Willcins formula. The infrared absorption spectra (IR) consist of characteristic vi-bration bands of Si-O-Si, Si-O-Zn, B-O in [BO3], B-O group, and Zn-O in [ZnO4]. Moreover, image storage and logical operation of the ZBSM film were carried out successfully through an experiment analogues of optical storage. | LI Fengfeng ZHANG Mingxi HOU Guiqin SHEN Yi LIU Zhigang LI Hongsheng | 2011 | Rare Metals2011，30，3： | 2 |
| 8 | The biology of bone morphogenetic protein signaling pathway in cerebrovascular system显示文摘Bone morphogenetic protein belongs to transcription growth factor superfamilyβ;bone morphogenetic protein signal pathway regulates cell proliferation,differentiation,and apoptosis among different tissues.Cerebrovascular system supplies sufficient oxygen and blood into brain to maintain its normal function.The disorder of cerebrovascular system will result into serious cerebrovascular diseases,which is gradually becoming a major threat to human health in modern society.In recent decades,many studies have revealed the underlying biology and mechanism of bone morphogenetic protein signal pathway played in cerebrovascular system.This review will discuss the relationship between the two aspects,aiming to provide new perspective for non-invasive treatment and basic research of cerebrovascular diseases. | Haishuang Tang Xiaoxi Zhang Gaici Xue Fengfeng Xu Qingsong Wang Pengfei Yang Bo Hong Yi Xu Qinghai Huang Jianmin Liu Qiao Zuo | 2021 | Chinese Neurosurgical Journal2021，7，4： | 2 |
| 9 | Hand, foot, and mouth disease in China, 2008–12: an epidemiological study显示文摘 | Weijia Xing Qiaohong Liao Cécile Viboud Jing Zhang Junling Sun Joseph T Wu Zhaorui Chang Fengfeng Liu Vicky J Fang Yingdong Zheng Benjamin J Cowling Jay K Varma Jeremy J Farrar Gabriel M Leung Hongjie Yu | 2014 | The Lancet Infectious Diseases2014，，： | 1 |
| 10 | Emergence of superconductivity from fully incoherent normal state in an iron-based superconductor (Ba_(0.6)K_(0.4))Fe_2As_2显示文摘In unconventional superconductors, it is generally believed that understanding the physical properties of the normal state is a pre-requisite for understanding the superconductivity mechanism. In conventional superconductors like niobium or lead, the normal state is a Fermi liquid with a well-defined Fermi surface and well-defined quasipartcles along the Fermi surface. Superconductivity is realized in this case by the Fermi surface instability in the superconducting state and the formation and condensation of the electron pairs(Cooper pairing). The high temperature cuprate superconductors, on the other hand, represent another extreme case that superconductivity can be realized in the underdoped region where there is neither well-defined Fermi surface due to the pseudogap formation nor quasiparticles near the antinodal regions in the normal state. Here we report a novel scenario that superconductivity is realized in a system with well-defined Fermi surface but without quasiparticles along the Fermi surface in the normal state.High resolution laser-based angle-resolved photoemission measurements have been performed on an optimally-doped iron-based superconductor(Ba_(0.6)K_(0.4))Fe_2As_2. We find that, while sharp superconducting coherence peaks emerge in the superconducting state on the hole-like Fermi surface sheets, no quasiparticle peak is present in the normal state. Its electronic behaviours deviate strongly from a Fermi liquid system. The superconducting gap of such a system exhibits an unusual temperature dependence that it is nearly a constant in the superconducting state and abruptly closes at Tc. These observations have provided a new platform to study unconventional superconductivity in a non-Fermi liquid system. | Jianwei Huang Lin Zhao Cong Li Qiang Gao Jing Liu Yong Hu Yu Xu Yongqing Cai Dingsong Wu Ying Ding Cheng Hu Huaxue Zhou Xiaoli Dong Guodong Liu Qingyan Wang Shenjin Zhang Zhimin Wang Fengfeng Zhang Feng Yang Qinjun Peng Zuyan Xu Chuangtian Chen Xingjiang Zhou | 2019 | Science Bulletin2019，64，1： | 1 |
| 11 | Interpretation of the Protocol for Prevention and Control of COVID-19 in China(Edition 8)显示文摘BACKGROUND Since the release of Protocol for Prevention and Control of COVID-19(Edition 7),coronavirus disease 2019(COVID-19)control and prevention has been facing new challenges in China with evolving domestic and global epidemiological situations.Since September 2020,China has experienced more than 20 local outbreak waves,all of which were able to be contained within a few weeks. | Fengfeng Liu Canjun Zheng Liping Wang Mengjie Geng Hui Chen Sheng Zhou Lu Ran Zhongjie Li Yanping Zhang Zijian Feng George FGao Zhaorui Chang | 2021 | China CDC weekly2021，3，25： | 1 |
| 12 | Influence of arbuscular mycorrhizae on photosynthesis and water status of maize plants under salt stress显示文摘 | Min Sheng Ming Tang Hui Chen Baowei Yang Fengfeng Zhang Yanhui Huang | 2008 | Mycorrhiza (-)2008，，6： | 1 |
| 13 | The effect of oxygen on the epitaxial growth of diamond显示文摘We studied the effect of oxygen on the growth quality of diamond epitaxial layers. After oxygen is added during the growth of the diamond epitaxial layer, as the thickness of the epitaxial layer increases, the full width at half maximum of the rocking curve of the(004) plane of diamond epitaxial layer increases continuously, and, in addition, the intensities of both the Raman peaks and the free exciton emission peaks of the diamond epitaxial layer decrease continuously. These experimental results demonstrate that as the thickness of the diamond epitaxial layer increases, the quality of the diamond epitaxial layer degrades. The strong etching effect of the OH radical groups in the plasma on the diamond epilayers leads to the degradation of their crystallinity. | Meng Gong Yanan Chen Wancheng Yu Peng Jin Zhanguo Wang Zhimin Wang Shenjin Zhang Feng Yang Fengfeng Zhang Qinjun Peng Zuyan Xu | 2018 | Journal of Semiconductors2018，39，12： | 1 |
| 14 | Application Progress of Headspace Gas Chromatography in Analytical Chemistry显示文摘This paper briefly expounds the basic principle and classification of headspace gas chromatography,summarizes its application in food analysis,environmental analysis and medical analysis,and forecasts the application prospect of headspace gas chromatography in analytical chemistry in the future. | Fengfeng ZHANG Yu ZHANG Xiaoxiang QIU | 2019 | Asian Agricultural Research2019，11，5： | 1 |
| 15 | Influence of arbuscular mycorrhizae on photosynthesis and water status of maize plants under salt stress 显示文摘 | Min Sheng Ming Tang Hui Chen Baowei Yang Fengfeng Zhang | 2007 | Mycorrhiza2007，18，6： | 1 |
| 16 | Analysis of parallel kinematic machine with kinetostaticmodelling method 显示文摘 | Zhang Dan Xi Fengfeng Chris M M | 2004 | Robotics and Computer-lntegrated Manufacturing2004，20，2： | 1 |
| 17 | Regiose-lective Oxyalkylation of Vinylarenes Catalyzed by Diatomite-Supported Manganese Oxide Nanoparticles显示文摘 | Sun Huaying Zhang Yonghui Guo Fengfeng | 2012 | J Org Chem2012，77，7： | 1 |
| 18 | A parallel robotic attachment and its remote manipulation显示文摘 | Wang Lihui Xi Fengfeng Zhang Dan | 2006 | Robotics and Computer- Integrated Manufacturing2006，22，56： | 1 |
| 19 | Antitumor properties of salinomycin on cisplatin-resistant human ovariancancer cells in vitro and in vivo: involvement of p38 MAPK activation显示文摘 | Bei Zhang Xueya Wang Fengfeng Cai Weijie Chen Uli Loesch Xiao Zhong | 2013 | Oncology Reports2013，，4： | 1 |
| 20 | Underlying mechanism of hemodynamics and intracranial aneurysm显示文摘In modern society,subarachnoid hemorrhage,mostly caused by intracranial aneurysm rupture,is accompanied by high disability and mortality rate,which has become a major threat to human health.Till now,the etiology of intracranial aneurysm has not been entirely clarified.In recent years,more and more studies focus on the relationship between hemodynamics and intracranial aneurysm.Under the physiological condition,the mechanical force produced by the stable blood flow in the blood vessels keeps balance with the structure of the blood vessels.When the blood vessels are stimulated by the continuous abnormal blood flow,the functional structure of the blood vessels changes,which becomes the pathophysiological basis of the inflammation and atherosclerosis of the blood vessels and further promotes the occurrence and development of the intracranial aneurysm.This review will focus on the relationship between hemodynamics and intracranial aneurysms,will discuss the mechanism of occurrence and development of intracranial aneurysms,and will provide a new perspective for the research and treatment of intracranial aneurysms. | Haishuang Tang Qingsong Wang Fengfeng Xu Xiaoxi Zhang Zhangwei Zeng Yazhou Yan Zhiwen Lu Gaici Xue Qiao Zuo Yin Luo Jianmin Liu Qinghai Huang | 2022 | Chinese Neurosurgical Journal2022，8，2： | 1 |
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