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| 1 | Specifically Binding of L-ficolin to N-glycans of HCV Envelope Glycoproteins E1 and E2 Leads to Complement Activation显示文摘 | Jun Liu Mohammed A.M. Ali Yinghua Shi Yinglan Zhao Fenglin Luo Jin Yu Tian Xiang Jie Tang Dongqing Li Quan Hu Wenzhe Ho Xiaolian Zhang | 2009 | Cellular & Molecular Immunology2009，6，4： | 8 |
| 2 | Fast start-up anammox process using Acyl-homoserine lactones(AHLs) containing supernatant显示文摘N-dodecanoyl homoserine lactone(C_(12)-HSL)was detected in the supernatant of an anammox granular sludge reactor(AGSR).C_(12)-HSL could enhance the specific anammox activity of anammox biomass.Adding C_(12)-HSL-containing AGSR supernatant into the continuously stirred tank reactors reduced the start-up time of the anammox process from80 to 66 days.Moreover,the nitrogen loading rate was also enhanced to 1.6 times that of the control reactor.AHLs could increase the secretion of extracellular polymeric substances and anammox obtained better enrichment with the addition of AHLs-containing AGSR supernatant.Denaturing gradient gel electrophoresis analysis further revealed that AHLs played a role in mediating microbial community parameters.In conclusion,adding AHL-containing supernatant could be an effective and economical way to accelerate the start-up of anammox. | Ran Zhao Hanmin Zhang Fan Zhang Fenglin Yang | 2018 | Journal of Environmental Sciences2018，30，3： | 7 |
| 3 | Anatomical variation of infra-pyloric artery origination: A prospective multicenter observational study (IPA-Origin)显示文摘Objective: Infra-pyloric artery(IPA) is an important anatomical landmark in treatment of gastric cancer and is the key vessel for pylorus-preserving gastrectomy and subgroup of infra-pyloric lymph nodes. However, its anatomical variation is not thoroughly understood. Our study aimed to clarify the origination of the IPA.Methods: We did this prospective, multicenter, open-label, observational study at gastric surgery departments of34 hospitals in China. Gastric cancer patients aged 18 years or older and scheduled to undergo elective total or distal gastrectomy were assigned. During the surgery, IPA dissecting and exposing the origination point with photographs or video clips were required. The primary outcome was the origination of the IPA. Analysis of variance, χ~2 tests and Fisher's tests were used to analyze the differences between groups. The study is registered at Clinicaltrials.gov(No. NCT03071237).Results: Between May 8 and July 31, 2017, 429 patients were assigned for the study, and 419(97.7%) patients had the IPA dissected and recorded through photograph or video and were included in the primary outcome analysis. The median age was 62 years old, and 73.7% were male. Among the patients, 78.5% received laparoscopic surgery. Single IPA origination was identified in 398(95.0%) patients, including gastroduodenal artery(GDA) in154(36.8%) patients, anterior superior pancreaticoduodenal artery(ASPDA) in 130(31.0%) patients, and right gastroepiploic artery(RGEA) in 114(27.2%) patients. Fifteen(3.6%) patients were identified with multiple IPA and 6(1.4%) patients were identified as IPA absence. The differences in the distribution of surgical approach(P=0.003) and geographic area(P=0.030) were statistically significant. No difference was shown in sex, age,gastrectomy type, tumor location, and clinical T, N and M stage.Conclusions: Our study found that the IPA originates from GDA, ASPDA and RGEA in similar proportions.Laparoscopic surgery may be more helpful in dissection of the IPA than open surgery. | Rulin Miao Jianjun Qu Zhengrong Li Daguang Wang Jiang Yu Weidong Zang Yong Li Fenglin Liu Jian Zhang Wu Song Kai Ye Su Yan Wei Wang Shuangyi Ren Lu Zang Changqing Jing Li Zhang Kuan Wang Weihua Fu Lin Fan Bin Liang Gang Zhao Jun Cai Li Yang Jiaming Zhu Jun You Kun Yang Qingxing Huang Zhaojian Niu Ning Ning Xingfeng Qiu Gang Ji Feng Liang Hua Huang Chao Gao Fei Shan Shuangxi Li Yongning Jia Lianhai Zhang Xiangji Ying Yan Zhang Zhaode Bu Xiangqian Su Gang Zhao Ziyu Li Jiafu Ji | 2018 | Chinese Journal of Cancer Research2018，30，5： | 5 |
| 4 | Generation of Tripotent Neural Progenitor Cells from Rat Embryonic Stem Cells显示文摘老鼠是为药理学和生理的研究的一个珍贵模型。胚胎的茎(物件) 房间衬里的 Germline 能干的老鼠成功地被建立了,维持物件细胞的自我更新的、无差别的状态的分子的网络也好揭开。然而,很少对区别策略和这些真老鼠 pluripotent 干细胞怎么产生特定的房间类型的内在的机制被知道。这研究的目的是调查物件房间的神经区别能力。借助于一个修改过程基于 激活mitogen 的蛋白质 kinase ( MAPK )和肝糖 synthase kinase 的以前的出版物联合 3 ( GSK3 )禁止者(二个禁止者, 2i )与喂调节中等,我们成功地从物件房间获得了高质量的老鼠胚胎植物或动物身体(美国南北战争时南军士兵)然后区分了他们到 tripotent 神经祖先。这些物件导出房间的神经祖先房间(rNPCs ) 能够自我更新并且产生所有三个神经的系,包括的星形细胞, oligodendrocytes,和神经原。而且,这些导出房间的神经原染色了的物件为 -aminobutyric 酸(伽马氨基丁酸) 和酷氨酸 hydroxylase (TH ) 积极。在摘要,我们为区分物件房间到 tripotent 开发一个试验性的系统神经祖先,它可以为学习象 Parkinson 的疾病和老鼠神经系统的开发那样的许多 neurodegenerative 混乱的致病为药理学测试和一个珍贵平台提供一个强大的工具。 | Zhenkun Wang Chao Sheng Tianda Li Fei Teng Lisi Sang Fenglin Cao Ziwei Wang Wanwan Zhu Wei Li Xiaoyang Zhao Zhonghua Liu Liu Wang Qi Zhou | 2012 | Journal of Genetics and Genomics2012，39，12： | 2 |
| 5 | Fluorometric method for the microdetermination of protein using indigo carmine显示文摘 | Zhang Xiaowei Zhao Fenglin Li Kean | 2001 | Microchemical Journal2001，68，2： | 1 |
| 6 | Determination of proteins with alizarin red s by Rayleigh light scattering technique显示文摘 | Zhong Hui Li Na Zhao Fenglin | 2004 | Talanta2004，62，1： | 1 |
| 7 | A Constructive Approach to Solving Geometric Constraint Systems显示文摘This paper proposes a constructive approach to solving geometric constraint systems.The approach incorporates graph-based and rule-based approaches, and achieves interactive speed.The paper presents a graph representation of geometric conStraint syStems, and discusses in detailthe algorithm of geometric reasoning based on poinl-cluster reduction. An example is made forillustration. | Gao Jianfeng Zhang Shensheng Bu Fenglin Zhao Jiyun(CIT Lab in Computer Science Dept.. Shanghai JiaoTong University. Shanghai 200030China University of Mining and Technology, Jiangsu 221008) | 1999 | Computer Aided Drafting,Design and Manufacturing1999，9，1： | 1 |
| 8 | Studies on a high encapsulation of colehicine by a niosome system 显示文摘 | Hao Yongmei Zhao Fenglin Li Na | 2002 | Int J Pharm2002，244，： | 1 |
| 9 | Determination of proteins with Alizarin Red S by Rayleigh light scattering technique显示文摘 | Hui Zhong Na Li Fenglin Zhao | 2004 | Talanta2004，62，： | 1 |
| 10 | TiOz and pol- yvinyl alcohol (PVA) coated polyester filter in bioreac- tor for wastewater treatment 显示文摘 | Lifen Liu Chuanqi Zhao Fenglin Yang | 2012 | Water Research2012，46，： | 1 |
| 11 | The First Halite Age Revealed by MC-ICP-MS U-series Dating in Lop Nur, Northwestern China显示文摘Objective Quaternary saline lakes are significant for paleoclimatic reconstruction due to the high sensitivity of salt minerals to environmental changes.However,salts in these areas with great thickness such as halite or potash representing extreme environments have severely blocked the application of traditional chronological methods.This is typified by Lop Nur,since accurate age to constrain | LU Fenglin LIU Chenglin JIAO Pengcheng ZHAO Jianxin ZHANG Hua | 2018 | Acta Geologica Sinica(English Edition)2018，92，2： | 1 |
| 12 | A comprehensive multi‐hazard risk assessment model for an urban agglomeration with multiple factors显示文摘To assist the Department of Emergency Management in understanding the overall risk characteristics and situation of an urban agglomeration for a reasonable risk prevention and control strategy,this study developed a comprehensive multi-hazard risk assessment model for an urban agglomeration with multiple factors.The proposed model includes disaster probability and disaster loss sub-models.The model evaluated four types of disaster risk in urban agglomerations:natural disasters,accidental disasters,public health incidents,and social security incidents.In addition,a variety of factors were integrated into the model,including the socioeconomic foundation of urban agglomerations,the oligopoly effect of core cities,historical disaster losses,the effect of disaster chains,the ability of disaster prevention and mitigation,and intercity coordinated rescue capabilities.Finally,the risk assessment model was applied to the Beijing-Tianjin-Hebei urban agglomeration.The assessment results were compared to the distribution of the new coronavirus pneumonia epidemic in the target urban agglomeration.The results showed that after analyzing the risk characteristics and evaluating the risk levels,the model not only showed the comprehensive risk levels and distribution of urban agglomerations but also revealed the high-risk areas and the key points of risk prevention and control.More importantly,the results obtained through the model can facilitate the strategic planning of disaster prevention and mitigation for urban agglomerations. | Changkun Chen Dongyue Zhao Fan He Fenglin Sun | 2023 | Journal of Safety Science and Resilience2023，4，1： | 1 |
| 13 | Fluorometric method for the microdetermination of protein using indigo carmine显示文摘 | Zhang Xiaowei Zhao Fenglin Li Kean | 2001 | Microchem J2001，68，： | 1 |
| 14 | Effect of 5%glycolic acid complex and 20%glycolic acid on mild-to-moderate facial acne vulgaris显示文摘To the Editor:Acne vulgaris is a chronic,inflammatory,and disfiguring skin disease with lesions,post-inflammatory hyperpigmentation,and scarring.Chemical peeling is a simple and well-tolerated procedure for mild-to-moderate acne.Glycolic acid(GA)is water-soluble and has the smallest molecular weight among all the alpha-hydroxy acids.High-concentration GA(20%–70%),applied at 2 to 4-week intervals in the hospital or cosmetology clinic,have proved effective for acne.[1]Low-concentration GA(10%)is safe and convenient,and can be used at home.[2]Up to now,differences in efficiency between low and high concentrations of GA for acne vulgaris have not been reported.This study compared the efficacy and safety of 5%GA complex and 20%GA for acne patients,to guide GA selection at different concentrations. | Jian Zhao Boyang Zhou Yan Hou Linfeng Li Fenglin Zhuo | 2022 | Chinese Medical Journal2022，135，21： | 0 |
| 15 | Improving the protective effects of a FGF for peripheral nerve injury repair using sulfated chitooligosaccharides显示文摘Injury to the peripheral nerves can result in temporary or life-long neuronal dysfunction and subsequent economic or social disability. Acidic fibroblast growth factor(a FGF) promotes the growth and survival of neurons and is a possible treatment for peripheral nerve injury. Yet,the actual therapeutic utility of a FGF is limited by its short half-life and instability in vivo. In the present study,we prepared sulfated chitooligosaccharides(SCOS),which have heparinlike properties,to improve the bioactivity of a FGF. We investigated the protective effects of SCOS with or without a FGF on RSC96 cells exposed to Na2 S2 O4 hypoxia/reoxygenation injury. Cell viability was measured by MTT assay and cytotoxicity induced by Na2 S2 O4 was assessed by lactate dehydrogenase(LDH) release into the culture medium. Pretreatment with a FGF and SCOS dramatically decreased LDH release after injury compared to pretreatment with a FGF or SCOS alone. We subsequently prepared an a FGF/SCOS thermo-sensitive hydrogel with poloxamer and examined its effects in vivo. Paw withdrawal thresholds and thermal withdrawal latencies were measured in rats with sciatic nerve injury. Local injection of the a FGF/SCOS hydrogels(a FGF: 40,80 μg/kg) increased the efficiency of sciatic nerve repair compared to a FGF(80 μg/kg) hydrogel alone. Especially a FGF/SCOS thermo-sensitive hydrogel decreased paw withdrawal thresholds from 117.75 ± 8.38(g,4 d) to 65.74 ± 3.39(g,10 d),but a FGF alone group were 140.58 ± 27.54(g,4 d) to 89.12 ± 5.60(g,10 d)(a FGF dose was 80 μg/kg,P < 0.05,n = 8). The thermal withdrawal latencies decreased from 11.61 ± 2.26(s,4 d) to 2.37 ±0.67(s,10 d). However,a FGF alone group were from 17.69 ± 1.47(s,4 d) to4.65 ± 1.73(s,10 d)(P < 0.05,n = 8). Furthermore,the a FGF/SCOS hydrogels also exhibited good biocompatibility in mice. In summary,SCOS improved the protective effects of a FGF in RSC96 cells injured with Na2S2O4 and increased the efficiency of nerve repair and recovery of function in rats with sciatic nerve injury. These findings pave an avenue for the development of novel prophylactic and therapeutic strategies for peripheral nerve injury. | Yanmei Liu Fenglin Yu Beibei Zhang Meng Zhou Yu Bei Yifan Zhang Jianzhong Tang Yan Yang Yadong Huang Qi Xiang Yueping Zhao Qian Liang Yang Liu | 2019 | Asian Journal of Pharmaceutical Sciences2019，14，5： | 0 |
| 16 | Sequentially releasing self-healing hydrogel fabricated with TGFβ3-microspheres and bFGF to facilitate rat alveolar bone defect repair显示文摘Resorption and loss of alveolar bone leads to oral dysfunction and loss of natural or implant teeth. Biomimetic delivery of growth factors based on stem cell recruitment and osteogenic differentiation, as the key steps in natural alveolar bone regenerative process, has been an area of intense research in recent years. A mesoporous self-healing hydrogel(DFH) with basic fibroblast growth factor(bFGF) entrapment and transforming growth factor β3(TGFβ3)-loaded chitosan microspheres(CMs) was developed. The formulation was optimized by multiple tests of self-healing, in-bottle inversion, SEM, rheological, swelling rate and in vitro degradation. In vitro tubule formation assays, cell migration assays, and osteogenic differentiation assays confirmed the ability of DFH to promote blood vessels, recruit stem cells, and promote osteogenic differentiation. The optimum DFH formula is 0.05 ml 4ArmPEG-DF(20%) added to 1 ml CsGlu(2%) containing bFGF(80 ng) and TGFβ3-microspheres(5 mg). The results of in vitro release studied by Elisa kit, indicated an 95% release of b FGF in7 d and long-term sustained release of TGFβ3. For alveolar defects rat models, the expression levels of CD29 and CD45, the bone volume fraction, trabecular number, and trabecular thickness of new bone monitored by Micro-CT in DFH treatment groups were significantly higher than others(*P < 0.05, vs Model). HE and Masson staining show the same results.In conclusion, DFH is a design of bionic alveolar remodelling microenvironment, that is in early time microvessels formed by b FGF provide nutritious to recruited endogenous stem cells, then TGFβ3 slowly released speed up the process of new bones formation to common facilitate rat alveolar defect repair. The DFH with higher regenerative efficiency dovetails nicely with great demand due to the requirement of complicated biological processes. | Fenglin Yu Dezhi Geng Zhanpeng Kuang Shiyi Huang Yating Cheng Yini Chen Fang Leng Yu Bei Yueping Zhao Qingxia Tang Yadong Huang Qi Xiang | 2022 | Asian Journal of Pharmaceutical Sciences2022，17，3： | 0 |
| 17 | Rayleigh light scattering and its applications to biochemical analysis显示文摘The recent applications of light scattering technique in biochemical analysis have been reviewed. The mechanic theories of resonance light scattering and Rayleigh light scattering (RLS), the relationships and differences between them, their applications and the interference factors in biochemistry analysis have been covered. By contrasting Rayleigh light scattering with double scattering and anti-scattering, the advantages of RLS have been pointed out. Finally, some prospects for the future application of this technique have been given. | Ke’an Li Chunqi Ma Ying Liu Fenglin Zhao Shenyang Tong | 2000 | Chinese Science Bulletin2000，45，5： | 0 |
| 18 | Evolution of Quaternary Depositional Environments in Lop Nor,Xinjiang:Sedimentary Records from LDK01 Drilling显示文摘Lop Nur is located in the interior of Asian and the lowest part in the eastern Tarim Basin.It is the final destination of major river systems in Tarim Basin and the accumulation center of salt materials(Xia,1987). | Lü Fenglin LIU Chenglin JIAO Pengcheng ZHAO Yanjun | 2014 | Acta Geologica Sinica(English Edition)2014，88，S1： | 0 |
| 19 | Effect of Soil on the Growth and Quality of Pepper during Different Durations of Continuous Planting显示文摘With the greenhouse soil that had been planted with cucumber as the control,the greenhouse soil that had been planted with pepper for 3,7,10 and 15 consecutive years was collected,and the effects of continuous cropping on plant height,stem diameter,leaf area,yield,photosynthetic pigment content and fruit quality of pepper were investigated by pot experiment. The results showed that with the extension of continuous cropping duration,the plant height,stem diameter and yield of pepper decreased significantly compared with the control; and the mass fraction of photosynthetic pigments declined,and the mass fractions of chlorophyll a and total chlorophyll were significantly lower than those of the control. Under the condition of continuous cropping,the fruit quality of pepper decreased significantly,and the mass fractions of soluble solids and soluble protein were significantly lower than those of the control. | Chunyan ZHAO Gengsheng LIANG Guoliang ZHAO Juan WANG Hongchang WEN Ruiyong TANG Fenglin CHENG | 2018 | Asian Agricultural Research2018，10，8： | 0 |
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