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| 1 | Volcanism at the Permian-Triassic Boundary in South China and Its Effects on Mass Extinction显示文摘This paper discusses the clayrocks widespread at the Permian-Triassic boundary, which are mostly of volcanic origin. Volcanogenetic textures, structures and minerals such as high-temperature quartz are found in clayrocks at the Permian-Triassic boundary in many places. Thousands of microspherules have been collected from the Boundary clayrocks, many of which exhibit the typical features of the process from melting to cooling and solidification. indicating that they were formed by volcanic eruption or extraterrestrial impact. Volcanic effects on the Permian-Triassic mass extinction may be reflected in conodonts, algae and ammonoids. The Boundary clayrocks are found in many Permian-Triassic sections along the coast of Tethys. Their orighin remains to be studied. | Yin Hongfu, Huang Siji, Zhang Kexin, Yang Fengqing, Ding Meihua, Bi Xianmei and Zhang Suxin China University of Geosciences, Wuhan, Hubei | 1989 | Acta Geologica Sinica(English Edition)1989，63，4： | 22 |
| 2 | Advancing application of mesenchymal stem cell-based bone tissue regeneration显示文摘Reconstruction of bone defects,especially the critical-sized defects,with mechanical integrity to the skeleton is important for a patient's rehabilitation,however,it still remains challenge.Utilizing biomaterials of human origin bone tissue for therapeutic purposes has provided a facilitated approach that closely mimics the critical aspects of natural bone tissue with regard to its properties.However,not only efficacious and safe but also costeffective and convenient are important for regenerative biomaterials to achieve clinical translation and commercial success.Advances in our understanding of regenerative biomaterials and their roles in new bone formation potentially opened a new frontier in the fast-growing field of regenerative medicine.Taking inspiration from the role and multicomponent construction of native extracellular matrix(ECM)for cell accommodation,the ECM-mimicking biomaterials and the naturally decellularized ECM scaffolds were used to create new tissues for bone restoration.On the other hand,with the going deep in understanding of mesenchymal stem cells(MSCs),they have shown great promise to jumpstart and facilitate bone healing even in diseased microenvironments with pharmacology-based endogenous MSCs rescue/mobilization,systemic/local infusion of MSCs for cytotherapy,biomaterials-based approaches,cell-sheets/-aggregates technology and usage of subcellular vesicles of MSCs to achieve scaffolds-free or cell-free delivery system,all of them have been shown can improve MSCsmediated regeneration in preclinical studies and several clinical trials.Here,following an overview discussed autogenous/allogenic and ECM-based bone biomaterials for reconstructive surgery and applications of MSCsmediated bone healing and tissue engineering to further offer principles and effective strategies to optimize MSCs-based bone regeneration. | Fengqing Shang Yang Yu Shiyu Liu Leiguo Ming Yongjie Zhang Zhifei Zhou Jiayu Zhao Yan Jin | 2021 | Bioactive Materials2021，6，3： | 13 |
| 3 | Utilization of Ogura CMS germplasm with the clubroot resistance gene by fertility restoration and cytoplasm replacement in Brassica oleracea L显示文摘Clubroot disease,a major plant root disease caused by Plasmodiophora brassicae,has become one of the most destructive diseases among cultivated cruciferous vegetables.However,clubroot-resistant Brassica oleracea materials are rare.A few clubroot-resistant cabbage varieties are available on the market,but all are Ogura cytoplasmic male sterile(CMS)types.Therefore,in this study,to reutilize the clubroot-resistant Ogura CMS germplasm of cabbage,a new fertility-restored Ogura CMS material,16Q2-11,was used as a bridge to transfer the clubroot resistance(CR)gene from the Ogura CMS cytoplasm to the normal cytoplasm by a two-step method(a fertility restoration and cytoplasm replacement method).In the first cross for fertility restoration of Ogura CMS clubroot-resistant cabbage(FRCRC),16Q2-11 was used as a restorer to cross with Ogura CMS materials containing the CR gene CRb2.Eleven Rfo-positive progenies were generated,of which four contained CRb2:F8-514,F8-620,F8-732 and F8-839.After inoculation with race 4 of P.brassicae,these four CRb2-positive individuals showed resistance.Furthermore,F8-514 and F8-839 were then used as male parents in the second cross of FRCRC to cross with cabbage inbred lines,resulting in the successful introgression of the CRb2 gene into the inbred lines.All offspring produced from this step of cross,which had a normal cytoplasm,showed a high resistance to race 4 of P.brassicae and could be utilized for the breeding of clubrootresistant cabbage varieties in the future.This is the first time that the Ogura CMS restorer has been used to restore the fertility of Ogura CMS clubroot-resistant cabbages,which could improve germplasm diversity in cabbage and provide a reference method for using CMS germplasm in Brassica crops. | Wenjing Ren Zhiyuan Li Fengqing Han Bin Zhang Xing Li Zhiyuan Fang Limei Yang Mu Zhuang Honghao Lv Yumei Liu Yong Wang Hailong Yu Yangyong Zhang | 2020 | Horticulture Research2020，7，1： | 7 |
| 4 | Effect on platelet aggregation activity: extracts from 31 Traditional Chinese Medicines with the property of activating blood and resolving stasis显示文摘OBJECTIVE: To evaluate the anti-platelet aggregation effects of extracts from 31 Traditional Chinese Medicines(TCM) with the property of activating blood and resolving stasis in terms of TCM theory.METHODS: The 31 TCMs extracts were prepared using water, 90% ethanol and ethyl acetate., and the effects on anti-platelet aggregation were tested on a platelet aggregation analyzer in vitro with adenosine 5'-diphosphate, bovine thrombin and arachi-donic acid(AA) as aggregation inducers, respectively. Aspirin was the positive control.RESULTS: Lots of the tested TCMs had inhibitory effects with concentration-dependent manner on platelet aggregations induced by various agonists.Especially, some of the TCMs such as Chuanxiong(Rhizoma Chuanxiong), Yanhusuo(Rhizoma Corydalis Yanhusuo) and Danshen(Radix Salviae Miltiorrhizae) showed good anti-platelet aggregation effect similar or higher than that in positive control group.CONCLUSION: The study provided scientific references that several TCMs such as Chuanxiong(Rhizoma Chuanxiong), Yanhusuo(Rhizoma Corydalis Yanhusuo) and Danshen(Radix Salviae Miltiorrhizae),possess the property of anti-platelet aggregation. | Chen Cen Wang Fengqin Xiao Wen Xia Zhining Hu Guang Wan Jianbo Yang Fengqing | 2017 | Journal of Traditional Chinese Medicine2017，37，1： | 7 |
| 5 | Volatile Compounds in the Flowers of Freesia Parental Species and Hybrids显示文摘几个世纪,小苍兰属植物是在养花工业的最重要的庄稼之一。这里,从双小苍兰属植物的全部花收集的水空间样品测定一,三四倍体小苍兰属植物栽培变种的三四倍体小苍兰属植物栽培变种,和种间染种用气体被分析用色层法分离结合了质量选择察觉者。总共, 75 不同混合物被识别。混合物主要是萜烯,烃,白酒,脂肪酸酉旨和芳香的班混合物。在这些之中,沉香醇除了无味的白四倍体 F 从所有有香味的花被检测。混合一。在 F 之间的沉香醇的稳定的继承。混合一 and 他们的 F1 子孙被观察。基于现在的分析,在小苍兰属植物和沉香醇的芳香之间的关系被讨论。 | Yang Fu Xiang Gao Yiqun Xue Yuejun Hui Fengqing Chen Quanping Su Li Wang | 2007 | Journal of Integrative Plant Biology2007，49，12： | 4 |
| 6 | Suggestion of Meishan Section as GlobalStratotype Section and Point (GSSP) of Permian-Triassic Boundary显示文摘ThisdatumwasobtainedfromthetopIcmofthe6cmthickBed3,whereasthedatum0.40isthemeanvalueof6samplesofBed26.TABLE3SUCCESSIONOFTHEPTBMARKERStogetherwithunevenlydistributCdirspikeareheresuggestedasauxiliarymarkersoftheboundary.Significanceofthechemicalanomalieswillbefurtherdiscussedintheparagraphofeventostratigraphy.EVENTOgyRATIGRAPHYACROSSTHEPTBOFMEISnANVolcedcEventThe'WhiteClay'orBed25iscomposedofinterbedsofilliteandaxxedmontmorillonite--illitelayerswithsubordinatekaolinite.The'BlackClay'orBed26isofmixedmontmori? | Yin Hongfu Wu Shunbao Ding Meihua Zhang Kexin Tong Jinnan Yang Fengqing(Faculty of Earth Sciences,China University of Geosciences, Wuhan 430074) | 1995 | Journal of Earth Science1995，14，1： | 3 |
| 7 | Auxin response factor 6A regulates photosynthesis,sugar accumulation,and fruit development in tomato显示文摘Auxin response factors(ARFs)are involved in auxin-mediated transcriptional regulation in plants.In this study,we performed functional characterization of SlARF6A in tomato.SlARF6A is located in the nucleus and exhibits transcriptional activator activity.Overexpression of SlARF6A increased chlorophyll contents in the fruits and leaves of tomato plants,whereas downregulation of SlARF6A decreased chlorophyll contents compared with those of wild-type(WT)plants.Analysis of chloroplasts using transmission electron microscopy indicated increased sizes of chloroplasts in SlARF6A-overexpressing plants and decreased numbers of chloroplasts in SlARF6A-downregulated plants.Overexpression of SlARF6A increased the photosynthesis rate and accumulation of starch and soluble sugars,whereas knockdown of SlARF6A resulted in opposite phenotypes in tomato leaves and fruits.RNA-sequence analysis showed that regulation of SlARF6A expression altered the expression of genes involved in chlorophyll metabolism,photosynthesis and sugar metabolism.SlARF6A directly bound to the promoters of SlGLK1,CAB,and RbcS genes and positively regulated the expression of these genes.Overexpression of SlARF6A also inhibited fruit ripening and ethylene production,whereas downregulation of SlARF6A increased fruit ripening and ethylene production.SlARF6A directly bound to the SAMS1 promoter and negatively regulated SAMS1 expression.Taken together,these results expand our understanding of ARFs with regard to photosynthesis,sugar accumulation and fruit development and provide a potential target for genetic engineering to improve fruit nutrition in horticulture crops. | Yujin Yuan Xin Xu Zehao Gong Yuwei Tang Mengbo Wu Fang Yan Xiaolan Zhang Qian Zhang Fengqing Yang Xiaowei Hu Qichen Yang Yingqing Luo Lihua Mei Wenfa Zhang Cai-Zhong Jiang Wangjin Lu Zhengguo Li Wei Deng | 2019 | Horticulture Research2019，6，1： | 3 |
| 8 | Timing of the terrestrial Permian-Triassic boundary biotic crisis:Implications from U-Pb dating of authigenic zircons显示文摘The Late Permian to Early Triassic transition represents one of the most important Phanerozoic mass extinction episodes. The cause of this event is still in debate between catastrophic and gradual mechanisms. This study uses the U-Pb method on zircons from the uppermost Permian/lowermost Triassic clay deposits at Chahe (Guizhou Province, SW China) to examine time constraints for this event. The results of both this and previous studies show that the ages of Bed 68a and 68c (the upper clay bed of the terrestrial Permian-Triassic boundary (PTB)) respectively are 252.6±2.8 and 247.5±2.8 Ma. This age (within the margin of error) almost accords with the upper clay bed (Bed 28) age of Meishan and the eruption age of Tunguss Basalt, and is so far the most accurate age obtained from terrestrial PTB. The claystone of Bed 68 was formed in the earliest Triassic. The biotic crisis occurred at nearly the same time in terrestrial and marine environments during Permian-Triassic interval; however the extinction patterns and processes are different. The extinction pattern of the terrestrial plants shows a major decline at the PTB after long-term evolution, followed by a retarded extinction of the relicts in the earliest Triassic. | YU JianXin LI HuiMin ZHANG SuXin YANG FengQing FENG QingLai | 2008 | Science China Earth Sciences2008，51，11： | 2 |
| 9 | A small functional intramolecular region of NodD was identified by mutation显示文摘在根瘤细菌属 leguminosarum bv。viciae,作为 LysR 类型 transcriptional 管理者(LTTR ) 的一个成员, NodD 施加自动调整并且面对 naringenin 激活另外的点头基因的抄写。LTTR 典型地由 N 终端 DNA 有约束力的领域和 C 终端组成规章的领域。在这研究,由系统的插入变化,在一些 NodD 的 12 氨基酸的一个区域作为功能的领域被识别。在这个区域的插入异种看起来获得组成地激活 nodA 基因的能力并且保留了他们的自动调整性质。这个识别区域被显示是通过用 Swiss-PDB 观众软件造的模型揭示了的 NodD 的绞链。报导作为 LysR 家庭的一个成员, NodD 被显示了包含影响它的性能的短 intramolecular 域是第一次。 | Bihe Hou Fengqing Li Xiao'er Yang Guofan Hong | 2009 | Acta Biochimica et Biophysica Sinica2009，41，10： | 2 |
| 10 | Characteristics of Bacillus cereus Spore Counts in Soils w ith Underlying Gold Mineralization in Northwestern Sichuan, China: Results from a Pilot Study显示文摘A pilot survey on a microbial mineral exploration method based on so il Bacillus cereus spore counts was carried out across three different gold mi ning regions, which vary in soil type, climate condition and geological setting in northwestern Sichuan, China. B horizon soils from these sites were analyzed for B. cereus spores, Au, Ag, Cu, Pb and Zn. The results show that the numbe rs of B. cereus spores generally increased in soils overlying gold mineraliz ation. Specifically, elevated spore counts were found in samples slightly offset from the outcrops of orebodies, whereas soils directly above the outcrops of or ebodies usually contained low spore counts. However, the background counts of B. cereus spores varied from place to place and were complicated by environmen tal and pedological factors, but the relative ratios of spore counts still were indicative of the underlying gold mineralization. | Wang Hongmei Yang Fengqing Qiao Shengying Faculty of Earth Sciences, China University of Geosciences, Wuhan 430074 | 2003 | Journal of China University of Geosciences2003，14，1： | 2 |
| 11 | A sensitive and selective method for the determination of flumorph residues in vegetables and fruits by HPLC–ESI-MS/MS显示文摘 | Yansong Wang Shihua Fan Xiangyong Cui Mingrui He Fengqing Zhang Chunhui Yang Chunye Zhang Ji Ma | 2011 | Talanta2011，，： | 1 |
| 12 | Identification and quantification of free radical scavengers in pu?erh tea by HPLC-DAD-MS coupled online with 2, 2'-azinobis (3-ethylbenzthiazolinesulfonic acid) diarnmonium salt assay显示文摘 | QIAN Zhengming GUAN Jia YANG Fengqing | 2008 | Journal of Agricultural and Food Chemistry2008，56，11： | 1 |
| 13 | Prepara- tive gas chromatography and its applications显示文摘 | Zuo HuaLi Yang FengQing Huang WeiHua | 2013 | J Chroma- togr Sci2013，51，70： | 1 |
| 14 | Palynological assemblages of non-marine rocks at the Permian–Triassic boundary, western Guizhou and eastern Yunnan, South China显示文摘 | Yuanqiao Peng Jianxin Yu Yongqun Gao Fengqing Yang | 2005 | Journal of Asian Earth Sciences2005，，4： | 1 |
| 15 | High-resolution terrestrial Permian–Triassic eventostratigraphic boundary in western Guizhou and eastern Yunnan, southwestern China显示文摘 | Yuanqiao Peng Suxin Zhang Tianxin Yu Fengqing Yang Yongqun Gao G.R. Shi | 2004 | Palaeogeography Palaeoclimatology Palaeoecology2004，，3： | 1 |
| 16 | An ecologically mixed brachiopod fauna from Changhsingian deep-water basin of South China: Consequence of en&Permian显示文摘 | Chen Z Q Shi G R Yang Fengqing | 2006 | Lethaia2006，39，： | 1 |
| 17 | The Songpan-Garze Massif: Its Relation to the QinlingFold Belt and Yangtze Platform and Developmental History显示文摘Whether there existed the Songpan-Garze massif is a controversial problem. This paper expounds and proves that the old basement of the massif is represented by the pre-Sinian granitic rock series. This massif and the South Qinling fold belt might both be a part of the old Yangtze platform. Rifting generated by the Caledonian orogeny in the terminal Early Palaeozoic caused the massif to be disintegrated from the northwestern part of the Yangtze platform. This disintegration, however, was not thorough, and the rift troughs were later gradually closed and filled up. The Emei taphrogeny that was initiated in the Early Permian Maokou’ an Stage involved a second disintegration of this massif from the Yangtze platform. The rift line largely goes along the Muli-Pingwu line. This rifting belongs to synchronous extensional rifting at peripheries of the Yangtze platform and in its interior, showing that the posterior, lateral and interior extension resulting from rapid northward shift of the Yangtze platform led | Yang Fengqing, Yin Hongfu, China U niversity of Geosciences. W uhan, HubeiYang HengshuNorthwestern Sichuan Geological Party, Mianyang, Sichuan and Lai XulongChina U niversity of Geosciences. W uhan, Hubei Fei Zhenbi | 1995 | Acta Geologica Sinica(English Edition)1995，69，1： | 0 |
| 18 | Level pinning of anti-PT-symmetric circuits for efficient wireless power transfer显示文摘Wireless power transfer(WPT) technology based on magnetic resonance(a basic physical phenomenon)can directly transfer energy from the source to the load without wires and other physical contacts, and has been successfully applied to implantable medical devices, electric vehicles, robotic arms and other fields.However, due to the frequency splitting of near-field coupling, the resonant WPT system has some unique limitations, such as poor transmission stability and low efficiency. Here, we propose anti-resonance with level pinning for high-performance WPT. By introducing the anti-resonance mode into the basic WPT platform, we uncover the competition between dissipative coupling and coherent coupling to achieve novel level pinning, and construct an effective anti-parity-time(anti-PT)-symmetric non-Hermitian system that is superior to previous PT-symmetric WPT schemes. On the one hand, the eigenvalue of the anti-PT-symmetric system at resonance frequency is always pure real in both strong and weak coupling regions, and can be used to overcome the transmission efficiency decrease caused by weak coupling, as brought about by, for example, a large size ratio of the transmitter to receiver, or a long transmission distance.On the other hand, due to the level pinning effect of the two kinds of coupling mechanisms, the working frequency of the system is guaranteed to be locked, so frequency tracking is not required when the position and size of the receiver change. Even if the system deviates from the matching condition, an efficient WPT can be realized, thereby demonstrating the robustness of the level pinning. The experimental results show that when the size ratio of the transmitter coil to the receiver coil is 4.29(which is in the weak coupling region), the transfer efficiency of the anti-PT-symmetric system is nearly 4.3(3.2) times higher than that of the PT-symmetric system when the matching conditions are satisfied(deviated). With the miniaturization and integration of devices in mind, a synthetic anti-PT-symmetric system is used to realize a robust WPT.Anti-PT-symmetric WPT technology based on the synthetic dimension not only provides a good research platform for the study of abundant non-Hermitian physics, but also provides a means of going beyond traditional near-field applications with resonance mechanisms, such as resonance imaging, wireless sensing and photonic routing. | Zhiwei Guo Fengqing Yang Haiyan Zhang Xian Wu Qiong Wu Kejia Zhu Jun Jiang Haitao Jiang Yaping Yang Yunhui Li Hong Chen | 2024 | National Science Review2024，11，1： | 0 |
| 19 | Investigation on the Metabolism of Salvianolic acid B, Tanshinone Ⅱ A, Ginsenoside Rg1 and Ginsenoside Rb1 from Danshen-Sanqi Herbal Pair in Zebrafish by Liquid Chromatography-Tandem Mass Spectrometry Analysis显示文摘Background:Salvianolic acid B(SAB),tanshinone IIA(TIIA),ginsenoside Rg1(GRg1)and ginsenoside Rb1(GRb1)are the main active components of Danshen-Sanqi herbal pair(DS-SQ),which is widely used in the treatment of cardiovascular diseases in Asia.The compatibility mechanisms of compound Chinese herbal preparation may be clarified to some degree by understanding the interactions of the active components based on their metabolic research.Furthermore,zebrafish is a convenient and feasible model to study the metabolism of drugs.Objective:To investigate the metabolism of SAB,TIIA,GRg1 and GRb1 in zebrafish by liquid chromatography-tandem mass spectrometry(LC-MS/MS)analysis.Methods:Zebrafish embryos after 48-hour hatching were divided into nine experimental groups.The blank group was exposed to 1 mL ultra-pure water.Eight drug-treated groups were exposed to 1 mL solution of SAB,TIIA,GRg1,GRb1,SAB and GRg1,SAB and GRb1,TIIA and GRg1,TIIA and GRb1,respectively.After homogenization,they were analyzed by LC-MS/MS.The Structures of the metabolites were determined by analyzing their corre-sponding mass spectra information and comparing the data with relevant literature.According to the change of the amount of metabolites,the metabolic effect between SAB,TIIA,GRg1 and GRb1 were investigated.Results:Eighteen metabolites and four parent drugs of SAB,TIIA,GRg1 and GRb1 in zebrafish were identified by LC-MS/MS,including methylation,degradation,reduction,dehydrogenation,hydroxylation,desugarization and glucuronidation metabolites.Furthermore,after being combined exposed of drugs,GRg1 and GRb1 could promote the metabolism of TIIA,while SAB and TIIA could promote the metabolism of GRg1 and GRb1 to different degree.Conclusion:By using LC-MS/MS analysis,zebrafish was successfully applied to study the metabolism of SAB,TIIA,GRg1 and GRb1,which is significance to explain the possible synergistic effect of components in DS-SQ through modifying the metabolism in zebrafish.This study can be helpful for the further research of DS-SQ. | Shijun Yin Congpeng Zhao Guang Hu Hua Chen Fengqing Yang | 2021 | Clinical Complementary Medicine and Pharmacology2021，1，1： | 0 |
| 20 | Map-based cloning and CRISPR/Cas9-based editing uncover BoNA1 as the causal gene for the no-anthocyanin-accumulation phenotype in curly kale (Brassica oleracea var. sabellica)显示文摘Brassica oleracea comprises several important vegetable and ornamental crops,including curly kale,ornamental kale,cabbage,broccoli,and others.The accumulation of anthocyanins,important secondary metabolites valuable to human health,in these plants varies widely and is responsible for their pink to dark purple colors.Some curly kale varieties lack anthocyanins,making these plants completely green.The genetic basis of this trait is still unknown.We crossed the curly kale inbred line BK2019(without anthocyanins)with the cabbage inbred line YL1(with anthocyanins)and the Chinese kale inbred line TO1000(with anthocyanins)to generate segregating populations.The no-anthocyanin trait was genetically controlled by a recessive gene,bona1.We generated a linkage map and mapped bona1 to a 256-kb interval on C09.We identified one candidate gene,Bo9g058630,in the target genomic region;this gene is homologous to AT5G42800,which encodes a dihydroflavonol-4-reductase-like(DFR-like)protein in Arabidopsis.In BK2019,a 1-bp insertion was observed in the second exon of Bo9g058630 and directly produced a stop codon.To verify the candidate gene function,CRISPR/Cas9 gene editing technology was applied to knock out Bo9g058630.We generated three bona1 mutants,two of which were completely green with no anthocyanins,confirming that Bo9g058630 corresponds to BoNA1.Different insertion/deletion mutations in BoNA1 exons were found in all six of the other no-anthocyanin kale varieties examined,supporting that independent disruption of BoNA1 resulted in no-anthocyanin varieties of B.oleracea.This study improves the understanding of the regulation mechanism of anthocyanin accumulation in B.oleracea subspecies. | Kaiwen Yuan Xinyu Zhao Wenru Sun Limei Yang Yangyong Zhang Yong Wang Jialei Ji Fengqing Han Zhiyuan Fang Honghao Lv | 2023 | Horticulture Research2023，10，8： | 0 |
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