|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Recently duplicated sesterterpene(C25) gene clusters in Arabidopsis thaliana modulate root microbiota显示文摘Land plants co-speciate with a diversity of continually expanding plant specialized metabolites(PSMs) and root microbial communities(microbiota).Homeostatic interactions between plants and root microbiota are essential for plant survival in natural environments.A growing appreciation of microbiota for plant health is fuelling rapid advances in genetic mechanisms of controlling microbiota by host plants.PSMs have long been proposed to mediate plant and single microbe interactions.However,the effects of PSMs,especially those evolutionarily new PSMs,on root microbiota at community level remain to be elucidated.Here,we discovered sesterterpenes in Arabidopsis thaliana,produced by recently duplicated prenyltransferase-terpene synthase(PT-TPS) gene clusters,with neo-functionalization.A single-residue substitution played a critical role in the acquisition of sesterterpene synthase(sesterTPS) activity in Brassicaceae plants.Moreover,we found that the absence of two root-specific sesterterpenoids,with similar chemical structure,significantly affected root microbiota assembly in similar patterns.Our results not only demonstrate the sensitivity of plant microbiota to PSMs but also establish a complete framework of host plants to control root microbiota composition through evolutionarily dynamic PSMs. | Qingwen Chen Ting Jiang Yong-Xin Liu Haili Liu Tao Zhao Zhixi Liu Xiangchao Gan Asis Hallab Xuemei Wang Juan He Yihua Ma Fengxia Zhang Tao Jin M. Eric Schranz Yong Wang Yang Bai Guodong Wang | 2019 | Science China(Life Sciences)2019，62，7： | 11 |
| 2 | Histological, hormonal and transcriptomic reveal the changes upon gibberellin-induced parthenocarpy in pear fruit显示文摘Phytohormones play crucial roles in fruit set regulation and development.Here,gibberellins(GA4+7),but not GA3,induced pear parthenocarpy.To systematically investigate the changes upon GA4+7 induced pear parthenocarpy,dynamic changes in histology,hormone and transcript levels were observed and identified in unpollinated,pollinated and GA4+7-treated ovaries.Mesocarp cells continued developing in both GA4+7-treated and pollinated ovaries.In unpollinated ovaries,mesocarp cells stopped developing 14 days after anthesis.During fruit set process,GA4+7,but not GA1+3,increased after pollination.Abscisic acid(ABA)accumulation was significantly repressed by GA4+7 or pollination,but under unpollinated conditions,ABA was produced in large quantities.Moreover,indole-3-acetic acid biosynthesis was not induced by GA4+7 or pollination treatments.Details of this GA–auxin–ABA cross-linked gene network were determined by a comparative transcriptome analysis.The indole-3-acetic acid transport-related genes,mainly auxin efflux carrier component genes,were induced in both GA4+7-treated and pollinated ovaries.ABA biosynthetic genes of the 9-cis-epoxycarotenoid dioxygenase family were repressed by GA4+7 and pollination.Moreover,directly related genes in the downstream parthenocarpy network involved in cell division and expansion(upregulated),and MADS-box family genes(downregulated),were also identified.Thus,a model of GA-induced hormonal balance and its effects on parthenocarpy were established. | Lulu Liu Zhigang Wang Jianlong Liu Fengxia Liu Rui Zhai Chunqin Zhu Huibin Wang Fengwang Ma Lingfei Xu | 2018 | Horticulture Research2018，5，1： | 7 |
| 3 | Study on Energy Conversion Characteristics in Volute of Pump as Turbine显示文摘A volute is a curved funnel with cross-sectional area increasing towards the discharge port.The volute of a centrifugal pump is the casing hosting the fluid being pumped by the impeller.In Pump-as-turbine devices(PAT),vice versa the volute plays the role of energy conversion element.In the present analysis,this process is analyzed using CFD.The results show that in the contraction section of volute the conversion between dynamic pressure energy and static pressure energy essentially depends on the reduction of flow area,while in the spiral section,frictional losses also play a significant role.From the throat to the end of the volute,the flow decreases in a wave-like manner. | Senchun Miao Hongbiao Zhang Fengxia Shi Xiaohui Wang Xijin Ma | 2021 | Fluid Dynamics & Materials Processing2021，17，1： | 5 |
| 4 | Epidemiological characteristics and temporal-spatial analysis of overseas imported dengue fever cases in outbreak provinces of China, 2005–2019显示文摘Background Overseas imported dengue fever is an important factor in local outbreaks of this disease in the mainland of China.To better prevent and control such local outbreaks,the epidemiological characteristics and temporal-spatial distribution of overseas imported dengue fever cases in provincial-level administrative divisions(PLADs)where dengue fever is outbreak in the mainland of China were explored.Methods Using the Chinese National Notifiable Infectious Disease Reporting Information System(CNNDS),we identified overseas imported dengue fever cases in dengue fever outbreak areas in the mainland of China from 2005 to 2019 to draw the epidemic curve and population characteristic distribution of overseas imported cases in each PLAD.Based on spatial autocorrelation analysis of ArcGIS 10.5 and temporal-spatial scanning analysis of SaTScan 9.5,we analyzed the temporal-spatial distribution of overseas imported dengue fever in dengue fever outbreak areas in the mainland of China.Results A total of 11,407 imported cases,mainly from Southeast Asia,were recorded from 2005 to 2019 in these 13 PLADs.Of which 62.1%were imported into Yunnan and Guangdong Provinces.Among the imported cases,there were more males than females,mainly from the 21–50 age group.The hot spots were concentrated in parts of Yunnan,Guangdong and Fujian Provinces.We found the cluster of infected areas were expanding northward.Conclusions Based on the analysis of overseas imported dengue cases in 13 PLADs of the mainland of China from 2005 to 2019,we obtained the epidemiological characteristics and spatial distribution of imported dengue cases.Border controls need to pay attention to key population sectors,such as 21–50 years old men and education of key populations on dengue prevention.There is a need to improve the awareness of the prevention and control of imported cases in border areas.At the same time,northern regions cannot relax their vigilance. | Xinchang Lun Yiguan Wang Chunchun Zhao Haixia Wu Caiying Zhu Delong Ma Mingfang Xu Jun Wang Qiyong Liu Lei Xu Fengxia Meng | 2022 | Infectious Diseases of Poverty2022，11，1： | 3 |
| 5 | Mossbauer effect probe of field-induced magnetic phase transition in LaFe13-xSix intermetallic compounds 显示文摘 | Cheng Zhaohua Di Naili Li Qingan Kou Zhiqi Luo Zhi Ma Xiao Wang Guangjun Hu Fengxia Shen Baogen | 2004 | Applied Physics Letters2004，85，10： | 1 |
| 6 | Mesenchymal stem cells engineered to express selectin ligands and IL-10 exert enhanced therapeutic efficacy in murine experimental autoimmune encephalomyelitis显示文摘 | Wenbin Liao Victor Pham Linan Liu Milad Riazifar Egest J. Pone Shirley Xian Zhang Fengxia Ma Mengrou Lu Craig M. Walsh Weian Zhao | 2016 | Biomaterials2016，，： | 1 |
| 7 | Tetrabutylphosphonium ions as a new swelling/de- lamination agent for layered compounds显示文摘 | GENG Fengxia MA Renzhi YAMAUCHI Y | 2014 | Chemical Communications2014，50，69： | 1 |
| 8 | Deep-Tissue Photothermal Therapy Using Laser Illumination at NIR-Ⅱa Window显示文摘Photothermal therapy(PTT)using near-infrared(NIR)light for tumor treatment has triggered extensive attentions because of its advantages of noninvasion and convenience.The current research on PTT usually uses lasers in the first NIR window(NIR-I;700–900 nm)as irradiation source.However,the second NIR window(NIR-II;1000–1700 nm)especially NIRIIa window(1300–1400 nm)is considered much more promising in diagnosis and treatment as its superiority in penetration depth and maximum permissible exposure over NIR-I window.Hereby,we propose the use of laser excitation at 1275 nm,which is approved by Food and Drug Administration for physical therapy,as an attractive technique for PTT to balance of tissue absorption and scattering with water absorption.Specifically,CuS-PEG nanoparticles with similar absorption values at 1275 and 808 nm,a conventional NIR-I window for PTT,were synthesized as PTT agents and a comparison platform,to explore the potential of 1275 and 808 nm lasers for PTT,especially in deep-tissue settings.The results showed that 1275 nm laser was practicable in PTT.It exhibited much more desirable outcomes in cell ablation in vitro and deep-tissue antitumor capabilities in vivo compared to that of 808 nm laser.NIR-IIa laser illumination is superior to NIR-I laser for deep-tissue PTT,and shows high potential to improve the PTT outcome. | Xunzhi Wu Yongkuan Suo Hui Shi Ruiqi Liu Fengxia Wu Tingzhong Wang Lina Ma Hongguang Liu Zhen Cheng | 2020 | Nano-Micro Letters2020，12，3： | 1 |
| 9 | Regulation of nitrogen starvation responses by the alarmone(p)ppGpp in rice显示文摘Nitrogen is an essential macronutrient for all living organisms and is critical for crop productivity and quality.In higher plants,inorganic nitrogen is absorbed through roots and then assimilated into amino acids by the highly conserved glutamine synthetase/glutamine:2-oxoglutarate aminotransferase(GS/GOGAT)cycle.How nitrogen metabolism and nitrogen starvation responses of plants are regulated remains largely unknown.Previous studies revealed that mutations in the rice ABNORMAL CYTOKININ RESPONSE1(ABC1)gene encoding Fd-GOGAT cause a typical nitrogen deficiency syndrome.Here,we show that ARE2(for ABC1 REPRESSOR2)is a key regulator of nitrogen starvation responses in rice.The are2 mutations partially rescue the nitrogen-deficient phenotype of abc1 and the are2 mutants show enhanced tolerance to nitrogen deficiency,suggesting that ARE2 genetically interacts with ABC1/Fd-GOGAT.ARE2 encodes a chloroplast-localized Rel A/Spo T homolog protein that catalyzes the hydrolysis of guanosine pentaphosphate or tetraphosphate(p)pp Gpp,an alarmone regulating the stringent response in bacteria under nutritional stress conditions.The are2 mutants accumulate excessive amounts of(p)pp Gpp,which correlate with lower levels of photosynthetic proteins and higher amino acid levels.Collectively,these observations suggest that the alarmone(p)pp Gpp mediates nitrogen stress responses and may constitute a highly conserved mechanism from bacteria to plants. | Hanwen Li Jinqiang Nian Shuang Fang Meng Guo Xiahe Huang Fengxia Zhang Qing Wang Jian Zhang Jiaoteng Bai Guojun Dong Peiyong Xin Xianzhi Xie Fan Chen Guodong Wang Yingchun Wang Qian Qian Jianru Zuo Jinfang Chu Xiaohui Ma | 2022 | Journal of Genetics and Genomics2022，49，5： | 1 |
| 10 | The role of molybdenum oxide as anode interfacial modification in the improvement of efficiency and stability in organic light-emitting diodes显示文摘 | Fengxia Wang Xianfeng Qiao Tao Xiong Dongge Ma | 2008 | Organic Electronics2008，，6： | 1 |
| 11 | Function of Slit/Robo signaling in breast cancer显示文摘因为他们经常在各种各样的肿瘤织物被使失去活性,裂缝和 Robo 被认为肿瘤 suppressors。这些基因密切在他们的倡导者与 CpG hypermethylation 被相关。表明小径的 Slit/Robo 据说涉及乳癌开发和转移。Slit/ Robo 的 Overexpression 导致它的肿瘤镇压由使表明小径的 -catenin/LEF/TCF 和 PI3K/Akt 失去活性或由在乳癌房间改变 -catenin/E-cadherin-mediated 房间房间粘附可能完成。而且,裂缝蛋白质的损失或他们的 Robo 受体 upregulates 在人的胸表明轴的 CXCL12/CXCR4 癌。另外,这条小径由调停调整乳癌房间的远迁居不仅 CXCL12/CXCR4 和 srGAPs 的下游的分子的 phosphorylation 例如 PI3K/ Src, RAFTK/ Pyk2,和 CDC42,而且由调整地图 kinases 的活动。这评论在在乳癌和它的分子的机制发信号的 Slit/Robo 的功能上包括最近的研究。 | Feng Gu Yongjie Ma Jiao Zhang Fengxia Qin Li Fu | 2015 | Frontiers of Medicine2015，9，4： | 1 |
| 12 | Impaired immunomodulatory ability of bone marrow mesenchymal stem cells on CD4 + T cells in aplastic anemia显示文摘 | Jianping Li Shihong Lu Shaoguang Yang Wen Xing Jianming Feng Wenqian Li Qinjun Zhao Hao Wu Meili Ge Fengxia Ma Hui Zhao Bin Liu Lei Zhang Yizhou Zheng Zhong Chao Han | 2012 | Results in Immunology2012，，： | 1 |
| 13 | Expression and purification of recombinant human hemangiopoietin in Escherichia coli显示文摘Objective:To express the soluble recombinant hemangiopoietin protein in E.coli BL21(DE3).Methods:Using human fetal live cDNA as a template,a partial cDNA fragment of HAPO coding N-terminal region was subcloned into plasmids pTrc99,pQE60 and pET32c to construct different recombinant prokaryotic expression systems.After selecting,the soluble rhHAPO fusion protein was expressed stably in E.coli BL21(DE3) by vector pET32c-HAPO and further isolated by nickelnitrilotriacetic acid(NTA) affinity chromatography.After cleavage with enterokinase,the rhHAPO protein was applied to Fast Flow SP sepharose column.Results:The rhHAPO protein had a purity of more than 95% and a good bioactivity based on the cell adhesion assay in ECV304 cells.Conclusion:We have established a protein engineering system to produce rhHAPO which may provide the possibility for clinical application. | Ren Qian Ma Fengxia Chen Zhong Lu Shihong Han Zhibo Liu Yongjun Xu Bin Zhang Xiangyu Han Zhongchao | 2008 | Journal of Medical Colleges of PLA(China)2008，23，3： | 0 |
| 14 | Prevalence of Reproductive Tract Infections and Association with Human Papillomavirus Infection Among Reproductive-Age Women—Six Tertiary Hospitals,China,June 2021-December 2022显示文摘Summary What is already known about this topic?Previous studies have indicated a possible association between reproductive tract infections(RTIs)and highrisk human papillomavirus(HPV)infection,but the evidence is still inconclusive.What is added by this report?This multicenter study found significantly higher positive rates of HPV,including general HPV,highrisk HPV. | Di Gao Jiayue Li Gengli Zhao Zhaohui Liu Hui Bi Dai Zhang Fengxia Xue Chen Liu Hongtao Ma Bei Lin Xu Wang Xiaosong Zhang Linhong Wang | 2024 | China CDC weekly2024，6，10： | 0 |
| 15 | Heterogeneity of neutrophils in cancer:one size does not fit all显示文摘Neutrophils play an essential role in the defense against bacterial infections and orchestrate both the innate and adaptive immune responses.With their abundant numbers,diverse function and short life span,these cells are at the forefront of immune responses,and have gained attention in recent years because of their presence in tumor sites.Neutrophil involvement pertains to tumor cells'ability to construct a suitable tumor microenvironment(TME)that accelerates their own growth and malignancy,by facilitating their interaction with surrounding cells through the circulatory and lymphatic systems,thereby influencing tumor development and progression.Studies have indicated both pro-and anti-tumor properties of infiltrating neutrophils.The TME can exploit neutrophil function,recruitment,and even production,thus resulting in pro-tumor properties of neutrophils,including promotion of genetic instability,tumor cell proliferation,angiogenesis and suppression of anti-tumor or inflammatory response.In contrast,neutrophils can mediate anti-tumor resistance by direct cytotoxicity to the tumor cells or by facilitating anti-tumor functions via crosstalk with T cells.Here,we summarize current knowledge regarding the effects of neutrophil heterogeneity under homeostatic and tumor conditions,including neutrophil phenotype and function,in cancer biology. | Song Chen Qingyu Zhang Lisha Lu Chunhui Xu Jiajia Li Jiali Zha Fengxia Ma Hongbo R.Luo Alan Y.Hsu | 2022 | Cancer Biology & Medicine2022，19，12： | 0 |
| 16 | Different Heterogeneous Fenton Reaction Based on Foam Carrier Loaded with Photocatalysts显示文摘The effect of heterogeneous Fenton reaction was studied on methylene blue(MB) and Nitrosomonas europaea(N. europaea) cells. Four Fenton systems were prepared and compared with each other, including Nickel Foam(NF)/TiO_2, NF/Bi_2WO_6, Ceramic foam(CM)/TiO_2, and CM/Bi_2WO_6. The order of effect of fenton reaction ranked as NF/TiO_2>CM/TiO_2>NF/Bi_2WO_6>CM/Bi_2WO_6. In acid or alkaline solution, the removal efficiency also decreased compared with neutral solution. With lower p H values, the nanoparticles were easier to break off from NF skeleton. Thus the synergetic effect of photocatalysis and fenton reaction can not take action. As for CM skeleton, the bond –Si-O-can bind with TiO_2 or Bi_2WO_6. The membrane fluidity was used as an indicating parameter. After being treated by Fenton reaction, N. europaea surface was rougher than the native bacterium and the bulges on cell surface became irregular, which is attributed to change of lipopolysaccharide patches. Polarization of N. europaea cell membrane in acid medium increased more obvious than alkaline medium. | 邱珊 LI Guangming DENG Fengxia MA Fang | 2018 | Journal of Wuhan University of Technology(Materials Science)2018，33，1： | 0 |
| 17 | Nanoengineering Metal–Organic Frameworks and Derivatives for Electrosynthesis of Ammonia显示文摘Electrocatalytic synthesis under mild conditions has become increasingly important as one of the practical alternatives for industrial applications,especially for the green ammonia(NH_(3))industry.A properly engineered electrocatalyst plays a vital role in the realization of superior catalytic performance.Among various types of promising nanomaterials,metal–organic frameworks(MOFs)are competitive candidates for developing efficient electrocatalytic NH_(3) synthesis from simple nitrogen-containing molecules or ions,such as N_(2) and NO_(3)^(−).In this review,recent advances in the development of electrocatalysts derived from MOFs for the electrosynthesis of NH_(3) are collected,categorized,and discussed,including their application in the N_(2) reduction reaction(NRR)and the NO_(3)^(−)reduction reaction(NO3RR).Firstly,the fundamental principles are illustrated,such as plausible mechanisms of NH_(3) generation from N_(2) and NO_(3)^(−),the apparatus of corresponding electrocatalysis,parameters for evaluation of reaction efficiency,and detection methods of yielding NH_(3).Then,the electrocatalysts for NRR processes are discussed in detail,including pristine MOFs,MOF-hybrids,MOF-derived N-doped porous carbons,single atomic catalysts from pyrolysis of MOFs,and other MOF-related materials.Subsequently,MOF-related NO3RR processes are also listed and discussed.Finally,the existing challenges and prospects for the rational design and fabrication of electrocatalysts from MOFs for electrochemical NH_(3) synthesis are presented,such as the evolution of investigation methods with artificial intelligence,innovation in synthetic methods of MOF-related catalysts,advancement of characterization techniques,and extended electrocatalytic reactions. | Daming Feng Lixue Zhou Timothy J.White Anthony K.Cheetham Tianyi Ma Fengxia Wei | 2023 | Nano-Micro Letters2023，15，11： | 0 |
| 18 | Transgenerational analysis of H3K4me3 and H3K27me3 by ChIP-Seq links epigenetic inheritance to metabolism显示文摘Histone methylation is a kind of important epigenetic modification which occurs on the lysine residue or arginine residue of histone tails(Zhang and Reinberg,2001).It takes part in multiple biological processes,including gene expression,genomic stability,stem cell maturity,genetic imprinting,mitosis and development(Fischle et al.,2005).Abnormal histone methylation pattern | Ke An Fengxia Du Hao Meng Guochao Li Minjie Zhang Zongzhi Liu Zitong Zhao Zilong Zhang Di Yu Dong Wang Caiyun Yang Wencui Ma Lin Yuan Meiting Zhou Lili Duan Li Jin Hui Li Yan Zhang Jianzhong Su Jie Qiao Yingli Sun | 2018 | Journal of Genetics and Genomics2018，45，3： | 0 |
| 19 | Flexible Diodes/Transistors Based on Tunable p-n-Type Semiconductivity in Graphene/Mn-Co-Ni-O Nanocomposites显示文摘We report a novel Mn-Co-Ni-O(MCN)nanocomposite in which the p-type semiconductivity of Mn-Co-Ni-O can be manipulated by addition of graphene.With an increase of graphene content,the semiconductivity of the nanocomposite can be tuned from p-type through electrically neutral to n-type.The very low effective mass of electrons in graphene facilitates electron tunneling into the MCN,neutralizing holes in the MCN nanoparticles.XPS analysis shows that the multivalent manganese ions in the MCN nanoparticles are chemically reduced by the graphene electrons to lower-valent states.Unlike traditional semiconductor devices,electrons are excited from the filled graphite band into the empty band at the Dirac points from where they move freely in the graphene and tunnel into the MCN.The new composite film demonstrates inherent flexibility,high mobility,short carrier lifetime,and high carrier concentration.This work is useful not only in manufacturing flexible transistors,FETs,and thermosensitive and thermoelectric devices with unique properties but also in providing a new method for future development of 2D-based semiconductors. | Lihong Su Zhou Yang Xitong Wang Ziao Zou Bo Wang Gary Hodes Ninghui Chang Yongyong Suo Zhibo Ma Haoxu Wang Yucheng Liu Junping Zhang Shuanhu Wang Yuefei Li Fengxia Yang Jixin Zhu Fei Gao Wei Huang Shengzhong Liu | 2022 | Research2022，，1： | 0 |
| 20 | Incidence of Major Adverse Cardiovascular and Cerebrovascular Events in Chinese Patients Undergoing Percutaneous Coronary Intervention with Iodixanol: An Observational Postauthorization Study显示文摘Objective:This study aimed to evaluate the major adverse cardiovascular and cerebrovascular events(MACCEs)and overall safety profile associated with iodixanol in Chinese patients undergoing percutaneous coronary intervention(PCI).Methods:Patients at 30 centers in China registered in the OpenClinic v3.6 database from October 30,2013,to October 7,2015,were included in the study.The primary endpoint was in-hospital MACCEs including target lesion revascularization(TLR),stroke,stent thrombosis,cardiac death,and PCI-related myocardial infarction(MI)within 72 h post-PCI.Secondary endpoints were MACCEs from 72 h to 30 d post-PCI and other safety events within 30 d post-PCI.Results:A total of 3,042 patients were enrolled.The incidence of MACCEs within 72 h post-PCI was 2.33%(n=71),including cardiac death(0.03%,n=1)and PCI-related MI(2.30%,n=70).The incidence of MACCEs from 72 h to 30 d post-PCI was 0.16%(n=5),including cardiac death(0.10%,n=3),PCI-related MI(0.03%,n=1),and TLR for stent thrombosis(0.03%,n=1).The incidence of composite angiographic or procedural complications was 2.86%(n=87);233(7.86%)patients had results suggesting contrast-induced acute kidney injury.Conclusions:These findings indicate that the use of iodixanol in Chinese patients undergoing PCI is associated with a low incidence of MACCEs,confirming its safety in this population. | Xiaozeng Wang Dengfeng Ma Tianchang Li Bao Li Xi Su Yanqing Wu Zhimin Du Zheng Ji Ping Yang Baisong Yang Xuebin Cao Junxia Li Fengxia Hou Ziping Cheng Banglong Xu Yaling Han | 2023 | Cardiology Discovery2023，3，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员