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| 1 | Management of recurrent rectal cancer:A population based study in greater Amsterdam显示文摘AIM: To analyze,retrospectively in a population-based study,the management and survival of patients with recurrent rectal cancer initially treated with a macroscopically radical resection obtained with total mesorectal excision (TME). METHODS: All rectal carcinomas diagnosed during 1998 to 2000 and initially treated with a macroscopically radical resection (632 patients) were selected from the Amsterdam Cancer Registry. For patients with recurrent disease,information on treatment of the recurrence was collected from the medical records. RESULTS: Local recurrence with or without clinically apparent distant dissemination occurred in 62 patients (10%). Thirty-two patients had an isolated local recurrence. Ten of these 32 patients (31%) underwent radical re-resection and experienced the highest survival (three quarters survived for at least 3 years). Eight patients (25%) underwent non-radical surgery (median survival 24 mo),seven patients (22%) were treated with radio-and/or chemotherapy without surgery (median survival 15 mo) and seven patients (22%) only received best supportive care (median survival 5 mo). Distant dissemination occurred in 124 patients (20%) of whom 30 patients also had a local recurrence. The majority (54%) of these patients were treated with radio-and/or chemotherapy without surgery (median survival 15 mo). Twenty-seven percent of these patients only received best supportive care (median survival 6 mo),while 16% underwent surgery for their recurrence. Survival was best in the latter group (median survival 32 mo). CONCLUSION: Although treatment options and survival are limited in case of recurrent rectal cancer after radical local resection obtained with TME,patients can benefit from additional treatment,especially if a radical resection is feasible. | Roel Bakx Otto Visser Judith Josso Sybren Meijer J Frederik M Slors J Jan B van Lanschot | 2008 | World Journal of Gastroenterology2008，14，39： | 17 |
| 2 | Firm size and the gains from acquisitions显示文摘 | Sara B Moeller Frederik P Schlingemann René M Stulz | 2004 | Journal of Financial Economics2004，，2： | 1 |
| 3 | Wealth Destruction on a Massive Scale? A Study of Acquiring - Firm Returns in the Recent Merger Wave 显示文摘 | Sara B Moeller Frederik P Schlingemann Ren6 M Stulz | 2005 | Journal of Finance2005，60，2： | 1 |
| 4 | Firm size and the gains from acquisitions 显示文摘 | Frederik P Schlingemann Rene M Stulz | 2004 | Journal of Financial Economics2004，，73： | 1 |
| 5 | Metal catalysts for the vinyl/addition polymerization of norbomene 显示文摘 | Frederik B Chfistoph J | 2009 | Coordination Chemistry Reviews2009，253，： | 1 |
| 6 | Carvedilol therapy in pediatric patients with congestive heart failure: a study in- vestigating clinical and pharmacokinetic parameters 显示文摘 | Stephanie L Thomas S Frederike B | 2002 | Am Heart J2002，143，： | 1 |
| 7 | The enable right vertricalar circulatory suport systom for bcating heast cornary artery bupase Groft surgery 显示文摘 | Gijs G Andre L Dekker Frederik H Vander-veen Keses B Prenger Audrey A Cramer S Jos G Davidshoshan I | 1999 | Ann Thorac Surg1999，68，： | 1 |
| 8 | Outbreak of Chikungunya on Reunion Island, Early Clinical and Laboratory Features in 157 Adult Patients 显示文摘 | Gianandrea B Patrice P Frederik S | 2007 | Clinical Infectious Diseases2007，44，： | 1 |
| 9 | Stealth liposomes: from theory to product 显示文摘 | Ceh B Winterhalter M Frederik PM | 1997 | Adv Drug Delivery Rev1997，24，： | 1 |
| 10 | Carvedilol therapy in pediatric patients with congestive heart failure: a study investi- gating clinical and pharmacokinetic parameters 显示文摘 | Stephanie L Thorns S Frederike B | 2002 | Am Heart J2002，143，： | 1 |
| 11 | Fruit and vegetable consumption and risk of aggressive and non-aggressive urothelial cell carcinomas in the European Prospective Investigation into Cancer and Nutrition显示文摘 | Martine M. Ros H. Bas Bueno-de-Mesquita Ellen Kampman Frederike L. Büchner Katja K.H. Aben Lars Egevad Kim Overvad Anne Tj?nneland Nina Roswall Francoise Clavel-Chapelon Marie Christine Boutron-Ruault Sophie Morois Rudolf Kaaks Birgit Teucher Steffen Weik | 2012 | European Journal of Cancer2012，，17： | 1 |
| 12 | High-Harmonic Generation and Correlated Electron Emission from Relativistic Plasma Mirrors at 1 kHz Repetition Rate显示文摘We report evidence for the first generation of XUV spectra from relativistic surface high-harmonic generation(SHHG)on plasma mirrors at a kilohertz repetition rate,emitted simultaneously with energetic electrons.SHHG spectra and electron angular distributions are measured as a function of the experimentally controlled plasma density gradient scale length Lg for three increasingly short and intense driving pulses:24 fs and a0=1:1,8 fs and a0=1:6,and finally 4 fs and a0≈2:1,where a0 is the peak vector potential normalized by mec/e with the elementary charge e,the electron rest mass me,and the vacuum light velocity c.For all driver pulses,we observe correlated relativistic SHHG and electron emission in the range Lg∈½λ/20,λ/4,with an optimum gradient scale length of Lg≈λ/10.This universal optimal Lg-range is rationalized by deriving a direct intensity-independent link between the scale length Lg and an effective similarity parameter for relativistic laser-plasma interactions. | Stefan Haessler Marie Ouillé Jaismeen Kaur Maïmouna Bocoum Frederik Böhle Dan Levy Louis Daniault Aline Vernier Jérôme Faure Rodrigo Lopez-Martens | 2022 | Ultrafast Science2022，，3： | 1 |
| 13 | Plasma carotenoids and vitamin C concentrations and risk of urothelial cell carcinoma in the European Prospective Investigation into Cancer and Nutrition12345显示文摘 | Martine M Ros H Bas Bueno-de-Mesquita Ellen Kampman Katja KH Aben Frederike L Büchner Eugene HJM Jansen Carla H van Gils Lars Egevad Kim Overvad Anne Tj?nneland Nina Roswall Marie Christine Boutron-Ruault Marina Kvaskoff Florence Perquier Rudolf Kaaks Jen | 2012 | American Journal of Clinical Nutrition2012，，4： | 1 |
| 14 | Stealth liposomes: from theory to product 显示文摘 | Ceh B Winterhaher M Frederik P M | 1997 | Adv Drug Delivery Rev1997，24，： | 1 |
| 15 | Target-based discovery of novel herbicide显示文摘 | Wolfgang L Frederik B Andreas R | 2004 | Curr Opin Plant Biol2004，7，： | 1 |
| 16 | Stealth liposomes: from theory to product 显示文摘 | Ceh B Winterhalter M Frederik PM | 1997 | Adv Drug Delivery Rev1997，24，： | 1 |
| 17 | Differentiation of pancreas carcinoma from healthy pancreatic tissue using mutipile b-values显示文摘 | Andreas L Frederik B L Miriam K | 2009 | Invest Radiol2009，44，12： | 1 |
| 18 | Magnetic resonance imaging of clinically suspected Salter-Harris I fracture of the distal fibula显示文摘 | Kathy B Unni GN Frederik FT | | 0，，： | 1 |
| 19 | Disturbed nitrogen metabolism associated with the hyperhydric status of fully habituated callus of sugarbeet显示文摘 | FREDERIK L D JEAN-PIERRE B THOMAS G CLAUDE H | 1993 | Physiologia Plantarum1993，88，： | 1 |
| 20 | Evaluation of AEDC con- current engine test capability显示文摘 | King B M Frederik J S Suits E | 2008 | AIAA 2008-16602008，，： | 1 |
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