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| 1 | Granular cell tumor of the pancreas:A case report and review of literature显示文摘Granular cell tumors,also called Abrikossof's tumors,were originally described by Abrikossof A in 1926.The f irst case of a pancreatic granular cell tumor was described in 1975 and only 6 cases have been reported.We describe a case of granular cell tumor in the pancreas showing pancreatic duct obstruction.Because imaging studies showed f indings compatible with those of pancreatic carcinoma,the patient underwent distal pancreatectomy.Histological examination showed that the tumor consisted of a nested growth of large tumor cells with ample granular cytoplasm and small round nuclei.The tumor cells expressed S-100 protein and were stained with neuron-specific enolase and periodic acid-Schiff,but were negative for desmin,vimentin,and cytokeratin.The resected tumor was diagnosed as a granular cell tumor.To our knowledge,this is the seventh case of Granular cell tumor of the pancreas to be reported. | Atsushi Kanno Kennichi Satoh Morihisa Hirota Shin Hamada Jun Umino Hiromichi Itoh Atsushi Masamune Shinichi Egawa Fuyuhiko Motoi Michiaki Unno Kazuyuki Ishida Tooru Shimosegawa | 2010 | World Journal of Gastrointestinal Oncology2010，2，2： | 5 |
| 2 | IgG4-unrelated type 1 autoimmune pancreatitis显示文摘A 50-year-old male was referred to our hospital for the evaluation of hyperproteinemia.Fluorodeoxyglucose positron emission tomography revealed high fluorodeoxyglucose uptake in the pancreas,bilateral lacrimal glands,submandibular glands,parotid glands,bilateral pulmonary hilar lymph nodes,and kidneys.Laboratory data showed an elevation of hepatobiliary enzymes,renal dysfunction,and remarkably high immunoglobulin(Ig) G levels,without elevated serum IgG4.Abdominal computed tomography revealed swelling of the pancreatic head and bilateral kidneys.Endoscopic retrograde cholangiopancreatography showed an irregular narrowing of the main pancreatic duct in the pancreatic head and stricture of the lower common bile duct.Histological examination by endoscopic ultrasonography-guided fine-needle aspiration revealed findings of lymphoplasmacytic sclerosing pancreatitis without IgG4-positive plasma cells.Abnormal laboratory values and the swelling of several organs were improved by the treatment with steroids.The patient was diagnosed as having type 1 autoimmune pancreatitis(AIP) based on the International Consensus Diagnostic Criteria.Therefore,we encountered a case of compatible type 1 AIP without elevated levels of serum IgG4 or IgG4-positive plasma cells.This case suggests that AIP phenotypes are not always associated with IgG4. | Eriko Nakano Atsushi Kanno Atsushi Masamune Naoki Yoshida Seiji Hongo Shin Miura Tetsuya Takikawa Shin Hamada Kiyoshi Kume Kazuhiro Kikuta Morihisa Hirota Keisuke Nakayama Fumiyoshi Fujishima Tooru Shimosegawa | 2015 | World Journal of Gastroenterology2015，21，33： | 3 |
| 3 | Pancreatic duct drainage using EUS-guided rendezvous technique for stenotic pancreaticojejunostomy显示文摘The patient was a 30-year-old female who had undergone excision of the extrahepatic bile duct and Rouxen-Y hepaticojejunostomy for congenital biliary dilatation at the age of 7.Thereafter,she suffered from recurrent acute pancreatitis due to pancreaticobiliary maljunction and received subtotal stomach-preserving pancreaticoduodenectomy.She developed a pancreatic fistula and an intra-abdominal abscess after the operation.These complications were improved by percutaneous abscess drainage and antibiotic therapy.How ever,upper abdominal discomfort and the elevation of serum pancreatic enzymes persisted due to stenosis from the pancreaticojejunostomy.Because we could not accomplish dilation of the stenosis by endoscopic retrograde cholangiopancreatography,we tried an endoscopic ultrasonography(EUS) guided rendezvous technique for pancreatic duct drainage.After transgastric puncture of the pancreatic duct using an EUS-fine needle aspiration needle,the guidewire was inserted into the pancreatic duct and finally reached to the jejunum through the stenotic anastomosis.We changed the echoendoscope to an oblique-viewing endoscope,then grasped the guidewire and withdrew it through the scope.The stenosis of the pancreaticojejunostomy was dilated up to 4 mm,and a pancreatic stent was put in place.Though the pancreatic stent was removed after three months,the patient remained symptomfree.Pancreatic duct drainage using an EUS-guided rendezvous technique was useful for the treatment of a stenotic pancreaticojejunostomy after pancreaticoduodenectomy. | Tetsuya Takikawa Atsushi Kanno Atsushi Masamune Shin Hamada Eriko Nakano Shin Miura Hiroyuki Ariga Jun Unno Kiyoshi Kume Kazuhiro Kikuta Morihisa Hirota Hiroshi Yoshida Yu Katayose Michiaki Unno Tooru Shimosegawa | 2013 | World Journal of Gastroenterology2013，19，31： | 3 |
| 4 | Diagnosis of autoimmune pancreatitis by EUS-FNA by using a 22-gauge needle based on the International Consensus Diagnostic Criteria显示文摘 | Atsushi Kanno Kazuyuki Ishida Shin Hamada Fumiyoshi Fujishima Jun Unno Kiyoshi Kume Kazuhiro Kikuta Morihisa Hirota Atsushi Masamune Kennichi Satoh Kenji Notohara Tooru Shimosegawa | 2012 | Gastrointestinal Endoscopy2012，，3： | 3 |
| 5 | miR‐197 induces epithelial–mesenchymal transition in pancreatic cancer cells by targeting p120 catenin显示文摘 | Shin Hamada Kennichi Satoh Shin Miura Morihisa Hirota Atsushi Kanno Atsushi Masamune Kazuhiro Kikuta Kiyoshi Kume Jun Unno Shinichi Egawa Fuyuhiko Motoi Michiaki Unno Tooru Shimosegawa | 2013 | J Cell Physiol2013，，6： | 3 |
| 6 | The revised Japanese clinical diagnostic criteria for chronic pancreatitis显示文摘 | Tooru Shimosegawa Keisho Kataoka Terumi Kamisawa Hiroyuki Miyakawa Hirotaka Ohara Tetsuhide Ito Satoru Naruse Naohiro Sata Koichi Suda Morihisa Hirota Yoshifumi Takeyama Keiko Shiratori Takashi Hatori Makoto Otsuki Yutaka Atomi Kentaro Sugano Masao Tanaka | 2010 | Journal of Gastroenterology2010，，6： | 2 |
| 7 | Linear metro transport systems for the 21st century显示文摘 | Eisuke Isobe Jinko Cho haru Morihisa | 1999 | Hitachi Review1999，48，3： | 1 |
| 8 | miR‐197 induces epithelial–mesenchymal transition in pancreatic cancer cells by targeting p120 catenin显示文摘 | Shin Hamada Kennichi Satoh Shin Miura Morihisa Hirota Atsushi Kanno Atsushi Masamune Kazuhiro Kikuta Kiyoshi Kume Jun Unno Shinichi Egawa Fuyuhiko Motoi Michiaki Unno Tooru Shimosegawa | 2013 | J. Cell. Physiol2013，，6： | 1 |
| 9 | Expression of survivin is correlated with cancer cell apoptosis and is involved in the development of human pancreatic duct cell tumors显示文摘 | KENNCH S KENZO K MORIHISA H | 2001 | Can2001，92，： | 1 |
| 10 | Treatment strategy for acute pancreatitis显示文摘 | Keita Wada Tadahiro Takada Koichi Hirata Toshihiko Mayumi Masahiro Yoshida Masamichi Yokoe Seiki Kiriyama Masahiko Hirota Yasutoshi Kimura Kazunori Takeda Shinju Arata Morihisa Hirota Miho Sekimoto Shuji Isaji Yoshifumi Takeyama Toshifumi Gabata Nobuya Ki | 2010 | Journal of Hepato - Biliary - Pancreatic Sciences2010，，1： | 1 |
| 11 | Improved field emission characteristics of individual carbon nanotube coated with boron nitride nanofilm 显示文摘 | MORIHISA Y KIMURA C YUKAWA M | 2008 | Journal of Vacuum Science & Technology B2008，26，2： | 1 |
| 12 | Analysis of atrioventricular nodal reentrant tachycardia with variable ventriculoatrial block: characteristics of the upper common pathway显示文摘 | Morihisa K Yamabe H Uemura T | 2009 | Pacing Clin Electrophysiol2009，32，： | 1 |
| 13 | Asymmetrical volumes of the right and left frontal and occipital regions of the human brain显示文摘 | Weiberger DR luchins DJ Morihisa J | 1982 | Neurology1982，11，： | 1 |
| 14 | Linear metro transport systems for the 21st century 显示文摘 | Eisuke Isobe Jinko Cho Itam Morihisa Toshihiko Sekizawa Ryuji Tanaka | 1999 | Hitachi Review1999，48，3： | 1 |
| 15 | Post-ERCP pancreatitis显示文摘 | Shinju Arata Tadahiro Takada Koichi Hirata Masahiro Yoshida Toshihiko Mayumi Morihisa Hirota Masamichi Yokoe Masahiko Hirota Seiki Kiriyama Miho Sekimoto Hodaka Amano Keita Wada Yasutoshi Kimura Toshifumi Gabata Kazunori Takeda Keisho Kataoka Tetsuhide It | 2010 | Journal of Hepato-Biliary-Pancreatic Sciences2010，，1： | 1 |
| 16 | The homeobox gene MSX2 determines chemosensitivity of pancreatic cancer cells via the regulation of transporter gene ABCG2显示文摘 | Shin Hamada Kennichi Satoh Morihisa Hirota | 2011 | Journal of Cellular Physiology2011，7，： | 1 |
| 17 | Endoscopic treatment for chronic pancreatitis: indications, technique, results显示文摘 | Morihisa Hirota Tooru Asakura Atsushi Kanno Tooru Shimosegawa | 2010 | Journal of Hepato - Biliary - Pancreatic Sciences2010，，6： | 1 |
| 18 | Pancreatic stellate cells enhance stem cell-like phenotypes in pancreatic cancer cells显示文摘 | Shin Hamada Atsushi Masamune Tetsuya Takikawa Noriaki Suzuki Kazuhiro Kikuta Morihisa Hirota Hirofumi Hamada Masayoshi Kobune Kennichi Satoh Tooru Shimosegawa | 2012 | Biochemical and Biophysical Research Communications2012，，2： | 1 |
| 19 | Diagnosis of autoimmune pancreatitis by EUS-FNA by using a 22-gauge needle based on the International Consensus Diagnostic Criteria显示文摘 | Atsushi Kanno Kazuyuki Ishida Shin Hamada Fumiyoshi Fujishima Jun Unno Kiyoshi Kume Kazuhiro Kikuta Morihisa Hirota Atsushi Masamune Kennichi Satoh Kenji Notohara Tooru Shimosegawa | 2012 | Gastrointestinal Endoscopy2012，，3： | 1 |
| 20 | Asymmetrical volumes of the right and left frontal and occipital regions of the human brain显示文摘 | Weiberger DR luchins DJ Morihisa J | 1982 | Neurology1982，11，： | 1 |
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