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| 1 | Origin of Oils in“Subtle pools”in the Dongying Depression,Bohai Bay Basin, China显示文摘摘要:微妙的陷井或油水池在 Dongying 消沉成为了一出重要探索戏, Bohai 海湾盆,华东。尽管有在探索的最近的成功,微妙的陷井的形成机制仍然不好被理解。在 Dongying 消沉的微妙的油水池的多数与主要具有在 mudstones 包含的透镜的盆地板 turbidite 沙的微妙的陷井在 Paleogene Shahejie 形成的 Es3 成员的中间的间隔被开发。在微妙的陷井的油以前被认为从一样的形成(Es3 ) 的包围来源岩石直接移植了。从消沉的 41 油和 41 件岩石样品的详细 geochemical 调查现在显示从微妙的陷井的油不能与包围 Es3 来源岩石被相关很好,它被高 Pr/Ph 描绘(> 1 ) ,低 Gammacerane/C30hopane,代表淡水湖的背景。在对比油特征低 Pr/Ph (< 1 ) 并且相对高的 Gammacerane 内容,与内在的 Es4 来源一起显示出一种基因亲密关系摇,它也有一样的质量,显示一个略有盐味的湖的背景。在 Es3 微妙的陷井的油可能从支配的上面的 Es4 来源岩石与贡献从混合来源被导出。要调用解释从 Es4 来源岩石分享油的因此异乎寻常的油迁居和累积机制需要,它可能通过 Es3 来源的厚低间隔来了摇没有明显结构或 stratigraphic 小径。我们建议微妙的油迁居小径可能这里起一个重要作用。这发现可以在 Dongying 消沉为未来探索和留下的资源评估有重要含意。 | LI Sumei JIANG Zhengxue LIU Keyu QIU Guiqiang GAO Yongjin | 2008 | Acta Geologica Sinica(English Edition)2008，82，1： | 3 |
| 2 | Formation and Accumulation of Hydrocarbons in the Central Uplift,Dongying Depression显示文摘A large number of crude oil and rock samples from various oil pools of the Central Uplift in Dongying Depression were investigated to reveal the origin and accumulation of hydrocarbons. The results showed that the composition and areal distribution of hydrocarbons vary with the location of the oil pools. An increasing trend of gammacerane/C30-hopane and steranes/hopanes but a decreasing trend of prystane/phytane (Pr/Ph) and 18(H)-/17(H)-trisnorhopane (Ts/Tm) ratios were observed from southwest to northeast. This indicates a variation of source rocks and hydrocarbon properties. An increasing trend of water salinity with much more input of algae-rich microorganisms in the deposition environment of the source rock was observed from southwest to northeast. However, the thermal maturity of the source rocks showed a decreasing trend in the same direction. Oil-to-oil and oil-to-source rock correlations showed that most oils were sourced from Es3 and Es4 members with a burial depth of more than 3,000-3,150 m and 2,700 m respectively. The oils in the Shinan and Ying 11 sand bodies, which were generally mixed with the Es4 sourced oils, came mostly from Es3 mudstones. It is quite significant that the Es4 derived oils migrated vertically for hundreds of meters and accumulated in an overlying lithologic pool of the Es3m, i.e., Ying 11 synclinal lithologic pool, which suggests that the mechanisms of migration and accumulation for subtle oil pools in the Dongying Depression are more complex than that of the previously expected. | Li Sumei Qiu Guiqiang Gao Yongjin Jiang Zhenxue | 2006 | Petroleum Science2006，3，3： | 3 |
| 3 | Historic changes in flux of matter and nutrient budgets in the Bohai Sea显示文摘Over the past four periods (1959-1960,1982-1983,1992-1993,and 1998-1999),the ecosystem of the Bohai Sea changed due to both a significant decrease of river water discharge from the Huanghe River and a reduction of precipitation. The shifts in nutrient chemistry could result in changes in the phytoplankton composition with an increased potential for non-diatom algal blooms. Simple box model was used to estimate the water-mass balance and nutrient budgets for the Bohai Sea. Water budgets indicate that the residual flow changed from out of the Bohai Sea before 1993,but became inflow to the Bohai Sea after then. The nutrient budgets developed indicate that the Bohai Sea was a sink for nutrients except for phosphate in 1959-1960 and 1982-1983 and for silicate in 1982-1983. Net water flow transports nutrients out of the Bohai Sea in 1959-1960,1982-1983 and 1992-1993,but into the sea in 1998-1999 due to climate changes,such as precipitation and subsequent freshwater discharge. The residual fluxes of nutrients are minor relative to atmospheric deposition and riverine inputs. Conversions of phosphate values to carbon by stoichiometric ratios were used to predict that the system was net heterotrophic before 1982-1983 and net autotrophic after then. Nutrient budgets can explain the change of nutrient concentrations in the Bohai Sea except nitrates,which should include the surface runoff. | LIU Sumei ZHANG Jing GAO Huiwang LIU Zhe | 2008 | Acta Oceanologica Sinica2008，27，5： | 3 |
| 4 | Quantitative prediction of mixed-source crude oils and its significance for understanding oil accumulation in subtle pools in the Dongying Depression,Bohai Bay Basin显示文摘常规 geochemical 途径在原油从 Paleogene Shahejie 形成的 Es3 和 Es4 成员导出的混合来源的比例的量的预言被利用。混合来源油在 Niuzhuang 在 Es3 成员(Es3 M ) 的中间的间隔被积累下垂,它是微妙的陷井在主要在 Dongying 消沉开发的 mudstones 以内的透镜的盆地板 turbidite 沙主要的 sags 之一, Bohai 海湾盆。结果证明大约 1892% 混合来源油与 5560% 的一般水准从 Es4 来源岩石被导出。与深差错联系的水库看起来有基因亲密关系上油的更多 Es4。导出 Es4 的油的一个高比例在 Es3 M 微妙的 lithological 发现在 Niuzhuang 的陷井下垂有长迁居距离。这建议包围来源岩石可能未必为微妙的陷井控制烃供应。微妙的迁居小径可以在垂直的油迁居起一个重要作用。在在从包围来源岩石的短迁居距离以内的这些透镜的 turbidite 沙岩陷井的烃累积的传统的概念是没由这研究支持。现在的结果与我们在在 Niuzhuang 的南方斜坡的 Bamianhe 油矿的不成熟的油下垂的以前的调查结果也一致实际上是主要在 Niuzhuang 的 depocenter 从 Es4 采购的混合来源油下垂,并且在 Dongying 消沉的 Es4 成员的石油潜力应该因此被重新估计。 | Li Sumei Liu Keyu Pang Xiongqi Li Maowen Jiang Zhenxue Qiu Guiqiang Gao Yongjin | 2008 | Petroleum Science2008，5，3： | 2 |
| 5 | CmBES1 is a regulator of boundary formation in chrysanthemum ray florets显示文摘Chrysanthemum(Chrysanthemum morifolium)is an ideal model species for studying petal morphogenesis because of the diversity in the flower form across varieties;however,the molecular mechanisms underlying petal development are poorly understood.Here,we show that the brassinosteroid transcription factor BRI1-EMS-SUPPRESSOR 1(CmBES1)in chrysanthemum(C.morifolium cv.Jinba)is important for organ boundary formation because it represses organ boundary identity genes.Chrysanthemum plants overexpressing CmBES1 displayed increased fusion of the outermost ray florets due to the loss of differentiation of the two dorsal petals,which developed simultaneously with the ventral petals.RNA-seq analysis of the overexpression lines revealed potential genes and pathways involved in petal development,such as CUP-SHAPED COTYLEDON(CUC2),CYCLOIDEA 4(CYC4),genes encoding MADS-box transcription factors and homeodomain-leucine zippers(HD-Zips)and auxin pathway-related genes.This study characterizes the role of CmBES1 in ray floret development by its modulation of flower development and boundary identity genes in chrysanthemum. | Peilei Cheng Yanan Liu Yiman Yang Hong Chen Hua Cheng Qian Hu Zixin Zhang Jiaojiao Gao Jiaxin Zhang Lian Ding Weimin Fang Sumei Chen Fadi Chen Jiafu Jiang | 2020 | Horticulture Research2020，7，1： | 2 |
| 6 | The over-expression of a chrysanthemum gene encoding an RNA polymerase II CTD phosphatase-like 1 enzyme enhances tolerance to heat stress显示文摘The enzyme RNAPII CTD phosphatase-like 1 is known as a transcriptional regulator of the plant response to various abiotic stresses.Here,the isolation of CmCPL1,a chrysanthemum(Chrysanthemum morifolium)gene encoding this enzyme is described.Its predicted 955 residue gene product includes the FCPH catalytic domain,two double-stranded RNA binding motifs,and a nuclear localization signal.A sub-cellular localization assay confirmed that CmCPL1 was expressed in the nucleus.CmCPL1 transcription was shown to be significantly inducible by heat stress.The over-expression and knockdown of CmCPL1,respectively,increased and diminished the tolerance of chrysanthemum to heat stress,which maybe dependent on the regulation of CmCPL1 and on the expression of downstream heat stress-responsive genes. | Yuying Qi Yanan Liu Zixin Zhang Jiaojiao Gao Zhiyong Guan Weimin Fang Sumei Chen Fadi Chen Jiafu Jiang | 2018 | Horticulture Research2018，5，1： | 2 |
| 7 | Distribution of DDT in a Typical DDT Waste Contaminated Site显示文摘 | Wenbin Liu Changliang Li Minghui Zheng Li Wang Sumei Li Te Ba Guijin Su Lirong Gao Lifei Zhang | 2008 | Bulletin of Environmental Contamination and Toxicology2008，，3： | 1 |
| 8 | Serine proteases excite myenteric neurons through protease-activated receptors in guinea pig small intestine 显示文摘 | Gao Chuanyun Liu Sumei Hu Hongzhen | 2002 | Gastroenterology2002，123，5： | 1 |
| 9 | Overexpression of CmSOS1 confers waterlogging tolerance in Chrysanthemum显示文摘Plants experiencing hypoxia(a shortage of oxygen)are unable to maintain aerobic respiration,which leads to an energy and carbohydrate deficit.The pervasive and rapid accumulation of ethylene is an early and reliable response to hypoxic stress(Sasidharan and Voesenek 2015),producing an uptick in the accumulation of reactive oxygen species(ROS).This in turn triggers apoptosis in root cortex cells,eventually leading to the formation of lysigenous aerenchyma,a tissue from which ethylene is readily lost(Loreti et al.2016).In plants exposed to prolonged waterlogging,group VII ethylene response factors operate to activate the suite of genes required to establish anaerobic metabolism(Gibbs et al.2011);some of these genes are also modulated by ROS(Narsai et al.2011;Sasidharan and Voesenek 2015).The transcriptional activation of genes encoding group VII ethylene response factors is regulated by the hypoxia response attenuator 1(HRA1)protein(Pucciariello and Perata 2017).A link between the oxygen sensing and ROS signaling has been established involving the hypoxia‐responsive universal stress protein 1(HRU1),which interacts with the respiratory burst oxidase homolog D(RBOHD)(Gonzali et al.2015).Salinity also tends to induce ROS production(You and Chan 2015). | Lijun Wang Jiaojiao Gao Zixin Zhang Weimiao Liu Peilei Cheng Wenting Mu Tong Su Sumei Chen Fadi Chen Jiafu Jiang | 2020 | Journal of Integrative Plant Biology2020，62，8： | 1 |
| 10 | Chrysanthemum CmWRKY53 negatively regulates the resistance of chrysanthemum to the aphid Macrosiphoniella sanborni显示文摘Chrysanthemum is frequently attacked by aphids,which greatly hinders the growth and ornamental value of this plant species.WRKY transcription factors play an important role in the response to biotic stresses such as pathogen and insect stresses.Here,chrysanthemum CmWRKY53 was cloned,and its expression was induced by aphid infestation.To verify the role of CmWRKY53 in resistance to aphids,CmWRKY53 transgenic chrysanthemum was generated.CmWRKY53 was found to mediate the susceptibility of chrysanthemum to aphids.The expression levels of secondary metabolite biosynthesis genes,such as peroxidase-and polyphenol oxidase-encoding genes,decreased in CmWRKY53-overexpressing(CmWRKY53-Oe)plants but dramatically increased in chimeric dominant repressor(CmWRKY53-SRDX)plants,suggesting that CmWRKY53 contributes to the susceptibility of chrysanthemum to aphids,possibly due to its role in the regulation of secondary metabolites. | Wanwan Zhang Tianwei Gao Peiling Li Chang Tian Aiping Song Jiafu Jiang Zhiyong Guan Weimin Fang Fadi Chen Sumei Chen | 2020 | Horticulture Research2020，7，1： | 1 |
| 11 | Research and de-sign of school ICT platform显示文摘 | LIU Ziyi GAO Sumei GAO Yaqun | 2005 | Electrical and mechani-cal product development2005，，2： | 1 |
| 12 | Liposome trade-off strategy in mitochondria-targeted NIR-cyanine: balancing blood circulation and cell retention for enhanced antitumor phototherapy in vivo显示文摘Cancer phototheranostics involving optical imaging-guided photodynamic therapy(PDT)and photothermal therapy(PTT)is a localized noninvasive approach in treating cancer.Mitochondria-targeted near-infrared(NIR)cyanines are excellent therapeutic photosensitizers of cancer.However,most mitochondria-targeted cyanines exist in the form of hydrophobic structures,which in vivo may cause cyanine aggregation during blood circulation,resulting in poor biocompatibility and limited therapeutic efficacy.Therefore,we developed a trade-off strategy by encapsulating mitochondria-targeted cyanines into liposomal bilayers(CyBI7-LPs),which balanced hydrophilicity that favored blood circulation and hydrophobicity that enhanced mitochondria tumor targeting.Moreover,CyBI7-LPs greatly minimized photobleaching of cyanine as self-generated reactive oxygen species(ROS)could rapidly escape from the liposomal bilayer,affording enhanced PTT/PDT efficacy.Bioorthogonal-mediated targeting strategy was further employed to improve uptake of tumor cells by modifying the liposomal surface to generate CyBI7-LPB.The CyBI7-LPB probe produced a tumor-to-background ratio(TBR)of approximately 6.4 at 24 HPI.Guiding by highly sensitive imaging resulted in excellent anti-tumor therapy outcomes using CyBI7-LPB due to the enhanced photothermal and photodynamic effects.This proposed liposomal nanoplatform exhibited a simple and robust approach as an imaging-guided synergistic anti-tumor therapeutic strategy. | Xianghan Zhang Sumei Zhao Zhiqing Gao Jialin Zhou Yuqiong Xia Jie Tian Changhong Shi Zhongliang Wang | 2021 | Nano Research2021，14，7： | 0 |
| 13 | Comparison of two methods for evaluating lower urinary tract symptoms in cervical cancer patients following radical hysterectomy显示文摘Objective:To compare the degree of agreement and consistency of urodynamic studies(UDS)with low urinary tract symptoms(LUTS)questionnaires for evaluating LUTS in cervical cancer patients following radical hysterectomy(RH)and pelvic lymphadenectomy.Methods:From January 2012 to March 2015,204 cervical cancer patients who underwent RH in 13 hospitals were evaluated using the Incontinence Questionnaire-Female Lower Urinary Tract Symptoms(ICIQ-FLUTS)and the Overactive Bladder Symptom Score(OABSS).Urodynamic tests were also performed on these patients during the same period.Results:Study participants’age ranged from 23 to 75 years,with a mean(standard deviation)of 48.0±9.3 years.Using questionnaires,the prevalence of patients with LUTS symptoms,including storage symptoms,voiding symptoms,stress urinary incontinence(SUI)and overactive bladder(OAB)was 86.3%,77.0%,62.7%,52.9%and 14.7%,respectively.For UDS,the corresponding prevalence was 89.7%,70.1%,66.7%,46.6%and 13.2%,respectively.The diagnostic concordance of questionnaires and UDS for storage symptoms,voiding symptoms,SUI and OAB was 79.9%,66.7%,66.7%,57.4%and 79.9%,respectively.For voiding symptoms,the correlation coefficient was 0.272,which was higher than that of storage symptoms,SUI and OAB. | Fang An Sha Wang Zhiqi Wang Lingying Wu Qiubo Lv Aiming Lv Hongwu Wen Jinsong Han Yumei Wu Yunong Gao Qing Liu Sumei Wang Hongxia Li Luwen Wang Yanlong Wang Ruifang Wu Huan Li Xiuli Sun | 2021 | Gynecology and Obstetrics Clinical Medicine2021，1，2： | 0 |
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