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| 1 | Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine显示文摘 | Tingting Zhu Ian A Roundtree Ping Wang Xiao Wang Li Wang Chang Sun Yuan Tian Jie Li Chuan He Yanhui Xu | 2014 | Cell Research2014，24，12： | 28 |
| 2 | Geospatial-temporal analysis of land-use changes in the Yellow River Delta during the last 40 years显示文摘Comprehensive study on land-use change of spatial pattern and temporal process is the key component in land use/land cover changes (LUCC) study nowadays. According to the theories and methods of Geo-information Tupu (Carto-methodology in Geo-information, CMGI) for geospatial and temporal analysis and integration models of spatial pattern and temporal processes in GIS, the paper puts forward Tupu methodology of land-use change and names the basic synthetic unit of spatial-temporal information Tupu unit. Tupu unit is the synthetic unit for geospatial-temporal analysis, which is synthesized by “space·attribute·process”features and composed of relatively homogeneous geographic unit and temporal unit. Based on the spatial features of 4 stages of land-use change in 1956, 1984, 1991, and 1996, a series of Tupu on land-use change in the Yellow River Delta (YRD) are created and studied in the paper, which includes 3 temporal units of spatial-temporal Tupu, process Tupu of land-use changes during the last 40 years, and reconstructions of a series of “arisen”Tupu, “arisen”process Tupu and pattern Tupu on land-use changes in the last 40 years by remapping tables of a reclassifying system. There are 3 methods of Tupu analysis on land-use change that are used to disclose change processes of land-use spatial conversion in YRD, such as spatial query and statistics, order of Tupu units by area and land-use conversion matrixes. In order to reveal the spatial pattern of land-use change processes, we analyze spatial-temporal changes of each Tupu above in various temporal units and spatial difference of pattern Tupu in the last 40 years by dynamic Tupu units. Tupu analysis on regional land-use is a promising trial on the comprehensive research of “spatial pattern of dynamic process”and “temporal process of spatial pattern”in LUCC research. The geo-information Tupu methodology would be a powerful and efficient tool on integrated studies of spatial pattern and temporal process in geoscience. | YE Qinghua1,3,4,LIU Gaohuan2,TIAN Guoliang1,CHEN Shenliang3,HUANG Chong2,CHEN Shupeng1,2,LIU Qingshen2,CHANG Jun2 & SHI Yanan2 1.State Key Laboratory of Remote Sensing Science,Institute of Remote Sensing Applications(IRSA),Chinese Academy of Science(CAS),Beijing 100101,China 2.Institute of Geographic Sciences and Natural Resources Research,CAS,Beijing 100101,China 3.State Key Laboratory of Estuarine and Coastal Research,East China Normal University,Shanghai 200062,China 4.Institute of Tibetan Plateau Research(ITPR),CAS,Beijing 100085,China Correspondence should be addressed to Ye Qinghua(email: yeqh@itpcas.ac.cn) | 2004 | Science China Earth Sciences2004，47，11： | 22 |
| 3 | Expression and regulation of IL-22 in the IL-17.producing CD4+T lymphocytes显示文摘IL-22 是在工作对感染支持纸巾的天生的免疫的 IL-10 家庭的新奇 cytokine。尽管 CD4+ 助手 T 淋巴细胞(TH ) 作为 IL-22 的来源被发现,这 cytokine 的规定糟糕被理解。这里,我们证明 IL-22 被也做 IL-17 的 TH 房间的一个新奇子集在 mRNA 和蛋白质层次表示。IL-22 和 IL-17 被发现被即时 PCR 以及 ELISA 分析被 TGFbeta 和 IL-6 并列地在 TH 区别期间调整。然而, IL-22 不调整 TH 区别;外长的 IL-22 或一个 IL-22 对手没在 TH 区别上有效果。这些数据表明 IL-17-producing T 房间表示的新奇 cytokine,并且建议在组织发炎和自体免疫的疾病表明小径的 IL-22 和 IL-17 的相互作用和协同作用。 | Yeonseok Chung Xuexian Yang Seon Hee Chang Li Ma Qiang Tian Chen Dong | 2006 | Cell Research2006，16，11： | 20 |
| 4 | miRNA targeted signaling pathway in the early stage of denervated fast and slow muscle atrophy显示文摘Denervation often results in skeletal muscle atrophy.Different mechanisms seem to be involved in the determination between denervated slow and fast skeletal muscle atrophy.At the epigenetic level,mi RNAs are thought to be highly involved in the pathophysiological progress of denervated muscles.We used mi RNA microarrays to determine mi RNA expression profiles from a typical slow muscle(soleus muscle) and a typical fast muscle(tibialis anterior muscle) at an early denervation stage in a rat model.Results showed that mi R-206,mi R-195,mi R-23 a,and mi R-30 e might be key factors in the transformation process from slow to fast muscle in denervated slow muscles.Additionally,certain mi RNA molecules(mi R-214,mi R-221,mi R-222,mi R-152,mi R-320,and Let-7e) could be key regulatory factors in the denervated atrophy process involved in fast muscle.Analysis of signaling pathway networks revealed the mi RNA molecules that were responsible for regulating certain signaling pathways,which were the final targets(e.g.,p38 MAPK pathway; Pax3/Pax7 regulates Utrophin and follistatin by HDAC4; IGF1/PI3K/Akt/m TOR pathway regulates atrogin-1 and Mu RF1 expression via Fox O phosphorylation).Our results provide a better understanding of the mechanisms of denervated skeletal muscle pathophysiology. | Gang Li Qing-shan Li Wen-bin Li Jian Wei Wen-kai Chang Zhi Chen Hu-yun Qiao Ying-wei Jia Jiang-hua Tian Bing-sheng Liang | 2016 | Neural Regeneration Research2016，11，8： | 15 |
| 5 | Variation of cyanobacteria with different environmental conditions in Nansi Lake,China显示文摘Nansi Lake is located on the east line of the South-to-North Water Diversion Project in China.A comprehensive study was carried out to investigate the spatial and temporal distribution of cyanobacteria in the lake from June 2008 to May 2011 based on monthly sample monitoring from five stations.The effect of environmental factors on cyanobacterial abundance was also evaluated.The cyanobacterial community contained 15 genera and 23 species.The cyanobacterial abundance of each monitoring station ranged from 0 to 1.53×10 7 cells/L with an average of 1.45×10 6 cells/L,which accounted for 11.66% of the total phytoplankton abundance.The dominant species of cyanobacteria were Pseudanabaena(32.94%) and Merismopedia(19.85%),not the bloom-forming algae such as Microcystis and Anabaena.In addition,the cyanobacterial community structure and water quality variables changed substantially over the survey period.Redundancy analysis(RDA) suggested that temperature and phosphorus were important environmental factors that affected cyanobacteria.Temperature was the most important factor affecting cyanobacterial abundance.The effect of phosphorus on cyanobacterial abundance was more notable in warm periods than in periods with low temperature. | Chang Tian Haiyan Pei Wenrong Hu Jun Xie | 2012 | Journal of Environmental Sciences2012，24，8： | 14 |
| 6 | Modeling the climate effects of different subregional uplifts within the Himalaya-Tibetan Plateau on Asian summer monsoon evolution显示文摘Considering the different uplifting time of different subregions of the Himalaya-Tibetan Plateau(TP),a series of numerical simulations have been conducted with the Community Atmosphere Model(CAM4) developed at the National Center for Atmospheric Research to explore the effects of the phased tectonic uplift of the Himalaya-TP on the evolution of Asian summer monsoons.The results show that the uplifts of the Himalaya and northern TP significantly affect the evolutions of South Asian summer monsoon and northern East Asian summer monsoon respectively.That is,the tectonic uplift of the Himalaya intensifies the South Asian summer monsoon circulation and increases the precipitation in South Asia,whereas the uplift of the northern TP intensifies the northern East Asian summer monsoon circulation and increases the precipitation in northern East Asia.Compared with previous simulations,current comparative analyses of modeling results for different subregional uplifts within the Himalaya-TP help deepen our understanding of the evolutionary history of Asian monsoons. | ZHANG Ran 1,JIANG DaBang 1,2,3,LIU XiaoDong 4 & TIAN ZhiPing 2,5 1 Climate Change Research Center,Chinese Academy of Sciences,Beijing 100029,China 2 Nansen-Zhu International Research Centre,Institute of Atmospheric Physics,Chinese Academy of Sciences,Beijing 100029,China 3 Key Laboratory of Regional Climate-Environment Research for Temperate East Asia,Chinese Academy of Sciences,Beijing 100029,China 4 State Key Laboratory of Loess and Quaternary Geology,Institute of Earth Environment,Chinese Academy of Sciences,Xi’an 710075,China 5 Graduate University of Chinese Academy of Sciences,Beijing 100049,China | 2012 | Chinese Science Bulletin2012，57，35： | 14 |
| 7 | Hyperbaric Oxygen and Ginkgo Biloba Extract Ameliorate Cognitive and Memory Impairment via Nuclear Factor Kappa-B Pathway in Rat Model of Alzheimer's Disease显示文摘 | Li-Da Zhang Li Ma Li Zhang Jian-Guo Dai Li-Gong Chang Pei-Lin Huang Xiao-Qiang Tian | 2015 | Chinese Medical Journal2015，，22： | 14 |
| 8 | Knockdown of FoxM1 by siRNA interference decreases cell proliferation, induces cell cycle arrest and inhibits cell invasion in MHCC-97H cells in vitro显示文摘 | Qi-fei WU Chang LIU Ming-hui TAI Dong LIU Lei LEI Rui-tao WANG Min TIAN Yi Lü | 2010 | Acta Pharmacologica Sinica2010，31，3： | 13 |
| 9 | Molecular Typing of Brucella Suis Collected from 1960s to 2010s in China by MLVA and PFGE显示文摘Brucellosis is a bacterial anthropozoonosis usually caused by Brucella abortus, Brucella melitensis, Brucella suis and Brucella canis. Brucella suis, the causative agent of swine brucellosis, is classified into five biovars and preferentially infects different animal hosts [1] . | LI Zhen Jun CUI Bu Yun CHEN Hai CHEN Jing Diao ZHAO Hong Yan PIAO Dong Ri JIANG Hai ZHANG Li TANG Xu KE Chang Wen YAO zhen TIAN Guo Zhong | 2013 | Biomedical and Environmental Sciences2013，26，6： | 13 |
| 10 | Pyogenic liver abscesses associated with nonmetastatic colorectal cancers: An increasing problem in Eastern Asia显示文摘AIM: To elaborate the clinicopathologic features of colorectal cancer-related pyogenic liver abscess (PLA). METHODS: Reported cases of colorectal cancer-related PLAs were collected from the literature published up to October 2011 and evaluated for their clinicopathologic features. Data of collected cases included demographics, clinical presentation, microbial findings and treatment. Categorical variables were compared by 2 analysis and continuous variables were evaluated using Student's t test. RESULTS: A total 96 cases of colorectal cancer-related PLA were collected from the previous literature. Most patients (60%) were male and 40% cases occurred in the age group of 61-70 years. Apart from some special types of PLA, there were significant differences in the microbiological spectrum between Eastern Asia and non-Eastern Asian countries, which implied different risk factors and courses of the disease. Gram negative bacteria especially Klebsiella pneumoniae (K. pneu- moniae ) PLA was predominant in Eastern Asia (80.0%) in contrast to non-Eastern Asian countries (P < 0.01). Meanwhile, most of the Eastern Asian patients exhibited smaller size of liver abscess and atypical presentation. Sigmoid colon and rectum (72.73%) were the main sites of tumor in Eastern Asian patients, whereas tumor sites were uneven among most of the non-Easter Asian PLA patients. CONCLUSION:K. pneumoniae PLA was strongly associated with colorectal cancer, especially those occurring in sigmoid colon and rectum, in elderly Eastern Asian male patients. | Kai Qu Chang Liu Zhi-Xin Wang Feng Tian Ji-Chao Wei Ming-Hui Tai Lei Zhou Fan-Di Meng Rui-Tao Wang Xin-Sen Xu | 2012 | World Journal of Gastroenterology2012，18，23： | 12 |
| 11 | Translation and validation of the Nepean Dyspepsia Index for functional dyspepsia in China显示文摘AIM:To assess the reliability and validity of the translated version of Nepean Dyspepsia Index (NDI) in Chinese patients with documented functional dyspepsia (FD).METHODS: The translation process included forward translation, back translation, pretest and cross-cultural adaptation. Reliability and validity of the translated version were examined by asking 300 subjects to complete the Chinese version of the NDI. The mean age of subjects was 39.24 years and 68.7% of the subjects were women. Internal consistency analysis with Cronbach's α was performed to test the reliability. Correlation analysis was used to assess the content validity. Factor analysis and structural equation models were used to assess the construct validity.RESULTS: The Cronbach's α coefficients ranged 0.833-0.960, well above the acceptable level of 0.70. Correlation analysis showed that each item had a strong correlation with the corresponding domain, but a weak correlation with other domains. Confi rmatory factor analysis indicated that the comparative fit index was 0.94, higher than the acceptable level of 0.90.CONCLUSION: The Chinese version of the NDI is a reliable and valid scale for measuring health-related quality of life and disease severity in Chinese patients with FD. | Xiao-Ping Tian Ying Li Fan-Rong Liang Guo-Jie Sun Jie Yan Xiao-Rong Chang Ting-Ting Ma Shu-Yuan Yu Xu-Guang Yang | 2009 | World Journal of Gastroenterology2009，15，25： | 11 |
| 12 | Schwannomatosis: a new member of neurofibromatosis family显示文摘 | CHEN Shan-lin LIU Chang LIU Bo YI Chuan-jun WANG Zhi-xin RONG Yan-bo ZHU Jin DING Yi TIAN Guang-lei | 2013 | Chinese Medical Journal2013，，14： | 11 |
| 13 | Environmental factors influencing cyanobacteria community structure in Dongping Lake, China显示文摘The present study was conducted to provide a detailed understanding of the variation in cyanobacterial communities of Dongping Lake, which is the final water volume adjusting and storing lake in the east route of the South-to-North Water Diversion Project in China. The spatial and temporal distribution of cyanobacteria was assessed from May 2010 to October 2012 based on monthly samples collected from three stations. Over the 30-month survey, 15 genera and 25 species of cyanobacteria were identified, with cyanobacterial abundance at each monitoring station ranging from undetected to 3.04×107 cells/L, average of 4.27×106 cells/L. The dominant cyanobacterial species were Pseudanabaena limnetica and Aphanizomenon issatschenkoi and not the usual bloom-forming genera such as Microcystis and Anabaena. Cyanobacterial community structure and water quality variables exhibited substantial changes over the period of survey. Redundancy analysis, Pearson correlations, and regression analysis were applied to analyze the relationships among the variables. The results suggested that temperature and chemical oxygen demand were key drivers of the cyanobacterial community composition in Dongping Lake. In addition, the concentration of inorganic nitrogen in the lake had a profound efect on the cyanobacterial abundance as a non-limiting factor in warm periods. | Xuetang Lu Chang Tian Haiyan Pei Wenrong Hu Jun Xie | 2013 | Journal of Environmental Sciences2013，25，11： | 11 |
| 14 | Designation and development of biomedical Ti alloys with finer biomechanical compatibility in long-term surgical implants显示文摘与优秀 biomechanical 相容性开发新钛合金是一个重要研究方向外科植入材料。现在的纸总结生物医学的钛合金的国际研究和开发。瞄准增加 biomechanical 相容性,它也介绍合金设计的探索和改进,机械处理,微观结构和阶段转变,并且以后最后为关于生物医学的钛合金的科学研究构画出方向。 | Zhen-Tao YU Ming-Hua ZHANG Yu-Xing TIAN Jun CHENG Xi-Qun MA Han-Yuan LIU Chang WANG | 2014 | Frontiers of Materials Science2014，8，3： | 9 |
| 15 | (+)-Borneol is neuroprotective against permanent cerebral ischemia in rats by suppressing production of proinflammatory cytokines显示文摘Stroke is one of the leading causes of disability and death globally.It occurs when a major artery is occluded in the brain and leads to death of cells within the injured tissue.(+)-Borneol,a simple bicyclic monoterpene extracted from traditional Chinese medicine,is widely used in various types of diseases.However,no study has proved the effects of(+)-borneol on functional recovery from permanent ischemic stroke and the mechanism is still unknown.Here,we report that in the rat model of permanent cerebral ischemia,we found that(+)-borneol(1.0 mg/kg) significantly ameliorated infarct size and neurological scores via reducing the expression of inducible nitric oxide synthase(iNOS)and tumor necrosis factor-alpha(TNF-α) in a dose dependent manner.Notably,(+)-borneol showed long-term effects on the improvement of sensorimotor functions in the photothrombotic model of stroke,which decreased the number of foot faults in the grid-walking task and forelimb asymmetry scores in the cylinder task,at least in part through reducing loss of dendritic spines in the length,brunch number and density.These findings suggest that(+)-borneol could serve as a therapeutic target for ischemic stroke. | Lei Chang Chun-Yu Yin Hai-Yin Wu Bin-Bin Tian Yan Zhu Chun-Xia Luo Dong-Ya Zhu | 2017 | The Journal of Biomedical Research2017，31，4： | 9 |
| 16 | Rapid Detection of Haemophilus influenzae and Haemophilus parainfluenzae in Nasopharyngeal Swabs by Multiplex PCR显示文摘Objective To establish multiplex PCR-based assays for detecting H.influenzae and H.parainfluenzae.And the PCR-based assays were applied to detect the carriage rates of H.influenzae and H.parainfluenzae in nasopharyngeal swab specimens which were collected from healthy children.Methods Multiplex primers for species-specific PCR were designed by using DNAstar soft based on the sequences of 16S rRNA genes from genus Haemophilus to detect H.influenzae and H.parainfluenzae.Results The sensitivity of the 16S rRNA PCR assay for detecting H.influenzae and H.parainfluenzae was 97.53% and 100% respectively,and the specificity was 95.89% and 96.63% respectively.Youden's Index on the ability to detect H.influenzae and H.parainfluenzae was 0.9342 and 0.9663 respectively.666 nasopharyngeal swab specimens were collected from healthy children.The detection rates of H.influenzae and H.parainfluenzae were 14.11% and 16.07% respectively by using isolation and culture methods.The detection rates of H.influenzae and H.parainfluenzae were 43.54% and 57.96% respectively by 16S rRNA PCR assays.The carriage rates of serotypes a,b,c,d,e,f and non-typeable isolates were 0% (0/666),0.15% (1/666),1.20% (8/666),0.15% (1/666),1.20% (8/666),1.80% (12/666),95.50% (636/666) respectively.Conclusion The multiplex PCR assays were very rapid,reliable and feasible methods for detection of H.influenzae and H.parainfluenzae in pharyngeal swab specimens which were compared to conventional isolation and culture methods.95.5% of H.influenzae strains in healthy children were nontypeable.The encapsulated or typable strains were mainly three serotypes which was c,e,and f serotype. | TIAN Guo Zhong ZHANG Li Juan WANG Xiao Lei ZHANG Li LI Shu Feng GU Chang Mei SUN Jian CUI Bu Yun | 2012 | Biomedical and Environmental Sciences2012，25，3： | 8 |
| 17 | Estimation of reproduction numbers of COVID-19 in typical countries and epidemic trends under different prevention and control scenarios显示文摘The coronavirus disease 2019(COVID-19)has become a life-threatening pandemic.The epidemic trends in different countries vary considerably due to different policy-making and resources mobilization.We calculated basic reproduction number(R0)and the time-varying estimate of the effective reproductive number(Rt)of COVID-19 by using the maximum likelihood method and the sequential Bayesian method,respectively.European and North American countries possessed higher (R0)and unsteady Rt fluctuations,whereas some heavily affected Asian countries showed relatively low (R0)and declining Rt now.The numbers of patients in Africa and Latin America are still low,but the potential risk of huge outbreaks cannot be ignored.Three scenarios were then simulated,generating distinct outcomes by using SEIR(susceptible,exposed,infectious,and removed)model.First,evidence-based prompt responses yield lower transmission rate followed by decreasing Rt.Second,implementation of effective control policies at a relatively late stage,in spite of huge casualties at early phase,can still achieve containment and mitigation.Third,wisely taking advantage of the time-window for developing countries in Africa and Latin America to adopt adequate measures can save more people’s life.Our mathematical modeling provides evidence for international communities to develop sound design of containment and mitigation policies for COVID-19. | Chen Xu Yinqiao Dong Xiaoyue Yu Huwen Wang Lhakpa Tsamlag Shuxian Zhang Ruijie Chang Zezhou Wang Yuelin Yu Rusi Long Ying Wang Gang Xu Tian Shen Suping Wang Xinxin Zhang Hui Wang Yong Cai | 2020 | Frontiers of Medicine2020，14，5： | 8 |
| 18 | Kinesin-4 Functions in Vesicular Transport on Cortical Microtubules and Regulates Cell Wall Mechanics during Cell Elongation in Plants显示文摘在植物,各向异性的房间扩大取决于作为轨道服务哪个大分子和泡被未知身份的马达 kinesins 搬运的外皮的微导管。我们使用了经历了柔韧的延伸发现涉及房间延伸并且发现 Gh KINESIN-4A 的 kinesins 的纤维富有地表示了的棉花(Gossypium hirsutum ) 。马达被 immunofluorescence 在与外皮的微导管被联系的像泡的结构上检测。在 Arabidopsis thaliana,在 KINESIN-4A/FRA1 的 orthologous 马达,以前在纤维细胞在第二等的生长期间在纤维素免职含有,被实时房间的成像在表示荧光灯地标注的功能的蛋白质的细胞检验。马达装饰了与 0.89m/min 的平均速度沿着外皮的微导管展出一个线性运动的像泡的粒子,它与连接到纤维素生合成的那些显著地不同。我们也在 KINESIN-4A/FRA1 发现了那并且在细胞墙力学,细胞延伸,和各种各样的植物、繁殖的器官的轴的生长在 KINESIN-4C 玩联系了冗余的角色,,损失在极大地提高的 KINESIN-4C,缺点在 KINESIN-4A/FRA1 地点由一个空变化引起了。双异种显示了房间墙在快速的房间延伸的正常阶段弄软的缺乏。而且,提高了包含 arabinose 的免职糖类在 kinesin-4 异种被检测。我们的调查结果建立了在在 flowering 植物沿着外皮的微导管和房间墙力学和房间延伸包含非有纤维质的部件的货物的 Kinesin-4-based 运输之间的一个连接。 | Zhaosheng Kong Motohide Ioki Siobhan Braybrook Shundai Li Zheng-Hua Ye Yuh-Ru Julie Lee Takashi Hotta Anny Chang Juan Tian Guangda Wang Bo Liu | 2015 | Molecular Plant2015，8，7： | 8 |
| 19 | Effective genome editing and identification of a regiospecific gallic acid 4-O-glycosyltransferase in pomegranate(Punica granatum L.)显示文摘Pomegranate(Punica granatum L.)trees are woody perennials that bear colorful and nutritious fruits rich in phenolic metabolites,e.g.,hydrolyzable tannins(HTs)and flavonoids.We here report genome editing and gene discovery in pomegranate hairy roots using Clustered Regularly Interspaced Short Palindromic Repeats(CRISPR)/CRISPR-associated protein 9(Cas9)(CRISPR/Cas9),coupled with transcriptome and biochemical analyses.Single guide RNAs(sgRNAs)were designed to target two UDP-dependent glycosyltransferases(UGTs),PgUGT84A23 and PgUGT84A24,which possess overlapping activities inβ-glucogallin(a galloylglucose ester;biosynthetic precursor of HTs)biosynthesis.A unique accumulation of gallic acid 3-O-and 4-O-glucosides(galloylglucose ethers)was observed in the PgUGT84A23 and PgUGT84A24 dual CRISPR/Cas9-edited lines(i.e.,ugt84a23 ugt84a24)but not the control(empty vector)or PgUGT84A23/PgUGT84A24 single edited lines(ugt84a23 or ugt84a24).Transcriptome and real-time qPCR analyses identified 11 UGTs with increased expression in the ugt84a23 ugt84a24 hairy roots compared to the controls.Of the 11 candidate UGTs,only PgUGT72BD1 used gallic acid as substrate and produced a regiospecific product gallic acid 4-O-glucoside.This work demonstrates that the CRISPR/Cas9 method can facilitate functional genomics studies in pomegranate and shows promise for capitalizing on the metabolic potential of pomegranate for germplasm improvement. | Lijing Chang Sheng Wu Li Tian | 2019 | Horticulture Research2019，6，1： | 8 |
| 20 | Editor’s note显示文摘In 1961, the Global Network Isotopes in Precipitation (GNIP) was operated by the IAEA in collaboration with WMO, and over 500 stations across the globe participated in this program. The initial objective of this program was the sys- | YAO TanDong & TIAN LiDe Key Laboratory of Tibetan Environment Changes and Land Surface Processes, Institute of Tibetan Plateau Research, Chinese Academy of Sciences, Beijing 100085, China State Key Laboratory of Cryosphere Sciences, Cold and Arid Regions Environment and Engineering Research Institute, Chinese Academy of Sciences, Lanzhou 730000, China | 2009 | Chinese Science Bulletin2009，54，16： | 8 |
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