|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Reversing drug resistance of soft tumor-repopulating cells by tumor cell-derived chemotherapeutic microparticles显示文摘颠倒使人重新住入肿瘤的房间(TRC ) 的药抵抗或起源的发展中的新奇途径像房间的癌症房间是迫切临床的需要改进癌症病人的结果。这里,我们显示出用肿瘤颠倒 TRC 的药抵抗的一条创新途径包含反肿瘤药的导出房间的 microparticles (T-MPs ) 。由比区分的癌症房间更可变形的优点, TRC 优先地收起 T-MPs 在进入房间以后释放反肿瘤药,它接着导致 TRC 的死亡。内在的机制包括防碍药流出并且支持这些药的原子入口。我们的调查结果在用有希望的临床的应用程序颠倒 TRC 的药抵抗在 T-MPs 的举起和一条新奇途径的有效性表明肿瘤房间柔软的重要性。 | Jingwei Ma Yi Zhang Ke Tang Huafeng Zhang Xiaonan Yin Yong Li Pingwei Xu Yanling Sun Ruihua Ma Tiantian Ji Junwei Chen Shuang Zhang Tianzhen Zhang Shunqun Luo Yang Jin Xiuli Luo Chengyin Li Hongwei Gong Zhixiong Long Jinzhi Lu Zhuowei Hu Xuetao Cao Ning Wang Xiangliang Yang Bo Huang | 2016 | Cell Research2016，26，6： | 17 |
| 2 | Major and trace element geochemistry of the mid-Bay of Bengal surface sediments: implications for provenance显示文摘The major and trace elements in 110 surface sediment samples collected from the middle of the Bay of Bengal(mid-Bay of Bengal) are analyzed to investigate provenance. Si levels are highest, followed by Al, and the distributions of these two elements are identical. The average CIA*(chemical index of alteration) value is 72.07,indicating that the degree of weathering of the sediments in the study area is intermediate between those of sediments of the Himalayan and Indian rivers. Factor analyses and discrimination function analyses imply that the two main provenances are the Himalayan and the Indian continent. The inverse model calculation of the Tinormalized element ratios of the Bay of Bengal sediments indicate an estimated average contribution of 83.5%and 16.5% from the Himalayan and peninsular Indian rivers to the study area, respectively. The Himalayan source contributes more sediment to the eastern part of the study area, whereas the western part receives more sediment from the Indian Peninsula than did the eastern part. The primary mechanisms for deposition of sediments in the study area are the transport of Himalayan matter by turbidity currents and river-diluted water and the transport of Indian matter to the study area by a surface circulation in the Bay of Bengal, particularly the East India Coastal Current. | LI Jingrui LIU Shengfa FENG Xiuli SUN Xingquan SHI Xuefa | 2017 | Acta Oceanologica Sinica2017，36，3： | 12 |
| 3 | Rapid repair of severely earthquake-damaged bridge piers with flexural-shear failure mode显示文摘An experimental study was conducted to investigate the feasibility of a proposed rapid repair technique for severely earthquake-damaged bridge piers with flexural-shear failure mode. Six circular pier specimens were first tested to severe damage in flexural-shear mode and repaired using early-strength concrete with high-fluidity and carbon fiber reinforced polymers (CFRP). After about four days, the repaired specimens were tested to failure again. The seismic behavior of the repaired specimens was evaluated and compared to the original specimens. Test results indicate that the proposed repair technique is highly effective. Both shear strength and lateral displacement of the repaired piers increased when compared to the original specimens, and the failure mechanism of the piers shifted from flexural-shear failure to ductile flexural failure. Finally, a simple design model based on the Seible formulation for post-earthquake repair design was compared to the experimental results. It is concluded that the design equation for bridge pier strengthening before an earthquake could be applicable to seismic repairs after an earthquake if the shear strength contribution of the spiral bars in the repaired piers is disregarded and 1.5 times more FRP sheets is provided. | Sun Zhiguo Wang Dongsheng Du Xiuli Si Bingjun | 2011 | Earthquake Engineering and Engineering Vibration2011，10，4： | 7 |
| 4 | Nitrogen application and intercropping change microbial community diversity and physicochemical characteristics in mulberry and alfalfa rhizosphere soil显示文摘Intercropping of mulberry(Morus alba L.)and alfalfa(Medicago sativa L.)is a new forestry-grass compound model in China,which can provide high forage yields with high protein.Nitrogen application is one of the important factors determining the production and quality of this system.To elucidate the advantages of intercropping and nitrogen application,we analyzed the changes of physicochemical properties,enzyme activities,and microbial communities in the rhizosphere soil.We used principal components analysis(PCA)and redundancy discriminators analysis to clarify the relationships among treatments and between treatments and environmental factors,respectively.The results showed that nitrogen application significantly increased pH value,available nitrogen content,soil water content(SWC),and urea(URE)activity in rhizosphere soil of monoculture mulberry.In contrast,intercropping and intercropping+N significantly decreased pH and SWC in mulberry treatments.Nitrogen,intercropping and intercropping+N sharply reduced soil organic matter content and SWC in alfalfa treatments.Nitrogen,intercropping,and intercropping+N increased the values of McIntosh diversity(U),Simpson diversity(D),and Shannon-Weaver diversity(H’)in mulberry treatments.However,PC A scatter plots showed clustering of monoculture mulberry with nitrogen(MNE)and intercropping mulberry without nitrogen(M0).Intercropping reduced both H’and D but nitrogen application showed no effect on diversity of microbial communities in alfalfa.There were obvious differences in using the six types of carbon sources between mulberry and alfalfa treatments.Nitrogen and intercropping increased the numbers of sole carbon substrate in mulberry treatments where the relative use rate exceeded 4%.While the numbers declined in alfalfa with nitrogen and intercropping.RDA indicated that URE was positive when intercropping mulberry was treated with nitrogen,but was negative in monoculture alfalfa treated with nitrogen.Soil pH and SWC were positive with mulberry treatments but were negative with alfalfa treatments.Intercropping with alfalfa benefited mulberry in the absence of nitrogen application.Intercropping with alfalfa and nitrogen application could improve the microbial community function and diversity in rhizosphere soil of mulberry.The microbial community in rhizosphere soil of mulberry and alfalfa is strategically complementary in terms of using carbon sources. | Xiuli Zhang Zhiyuan Teng Huihui Zhang Dunjiang Cai Jingyun Zhang Fanjuan Meng Guangyu Sun | 2021 | Journal of Forestry Research2021，32，5： | 5 |
| 5 | xperimental investigation on cumulative propagation of thin film buckling under cyclic load显示文摘As instrument technology is needed for rapid determination of the smaller,thinner and lighter specimens,more stringent demands are related to thin films such as micro-electro-mechanical systems(MEMS),dielectric coatings and electronic packaging.Therefore,the requirement for testing platforms for rapidly determine the mechanical properties of thin films is increasing.Buckling of a film/substrate system could offer a variety of applications,ranging from stretchable electronics to micro-nanoscale metrology.In this paper,a fatigue-loading device has been designed to make the cyclic loading available for investigating the cumulative propagation of thin film buckling.The straight side buckling of thin compressed titanium film with the thickness of 50 nm deposited on organic glass substrates is investigated by using an optical microscope.The cumulative buckling propagation under the cyclic loading of a sequence of peak compression with the frequency 1 Hz is recorded by CCD camera.The buckling extension lengths are calculated by digital image measurement technology. | WANG ShiBin JIA HaiKun LI LinAn SUN Heng CUI DiQiang GUO ZhenShan XUE XiuLi | 2011 | Science China(Technological Sciences)2011，54，6： | 4 |
| 6 | Phase evolution, microstructure, electric properties of (Ba1–xBi0.67xNa0.33x)(Ti1–xBi0.33xSn0.67x)O3 ceramics显示文摘(Ba1–xBi0.67xNa0.33x)(Ti1–xBi0.33xSn0.67x)O3(abbreviated as BBNTBS,0.02≤x≤0.12)ceramics were fabricated via a traditional solid state reaction method.The phase transition of BBNTBS from tetragonal to pseudo cubic is demonstrated by XRD and Raman spectra.The BBNTBS(x=0.1)ceramics have decent properties with a highεr(~2250),smallΔε/ε25℃ values of±15%over a wide temperature range from–58 to 171℃,and low tanδ≤0.02 from 10 to 200℃.The basic mechanisms of conduction and relaxation processes in the high temperature region were thermal activation,and oxygen vacancies might be the ionic charge transport carriers.Meanwhile,BBNTBS(x=0.1)exhibited decent energy storage density(Jd=0.58 J/cm3)and excellent thermal stability(the variation of Jd is less than 3% in the temperature range of 25–120℃),which could be a potential candidate for high energy density capacitors. | Xiuli CHEN Xu LI Huanfu ZHOU Jie SUN Xiaoxia LI Xiao YAN Congcong SUN Junpeng SHI | 2019 | Journal of Advanced Ceramics2019，8，3： | 4 |
| 7 | Pharmacokinetic investigation on nteraction between hydrophilic lithospermic acid B and lipophilic tanshinone IIA in rats:an experimental study显示文摘OBJECTIVE:To elucidate the interaction between hydrophilic lithospermic acid B and lipophilic tanshinone Ⅱ A in rats.METHODS:A reliable high-performance liquid chromatography method was adopted for simultaneous determination of lithospermic acid B and tanshinone Ⅱ A in rat plasma,through which the pharmacokinetic interaction between lithospermic acid B and tanshinone Ⅱ A by intravenous injection was investigated.RESULTS:The simultaneous intravenous injection of tanshinone Ⅱ A and lithospermic acid B significantly altered the pharmacokinetic parameters of both compounds when compared with the individual intravenous administration of each compound.The area under the concentration-time curve of tanshinone Ⅱ A and lithospermic acid B increased by 18.35 and 59.31%,respectively.The mean retention time of tanshinone Ⅱ A and lithospermic acid B increased,respectively,from 9.3 to 32.8 h and20.2 to 49.1 h.The concomitant use of tanshinoneⅡ A magnified the volume of distribution at steady state(V_(ss)) and time for the drug in the plasma to reduce the highest concentration by half(t_(1/2)) of lithospermic acid B,while at the same time the V_(ss) and t_(1/2)of tanshinone Ⅱ A changed significantly in the presence of lithospermic acid B.CONCLUSION:Lithospermic acid B and tanshinone D A interact with each other following simultaneous intravenous injection in rats and this observation may expand the clinical use of Danshen(Radix Salviae Miltiorrhizae). | Wang Xiuli Gao Wei Sun Mao | 2015 | Journal of Traditional Chinese Medicine2015，35，2： | 3 |
| 8 | Pan-cancer analysis of somatic mutations across 21 neuroendocrine tumor types显示文摘 | Yanan Cao Weiwei Zhou Lin Li Jiaqian Wang Zhibo Gao Yiran Jiang Xiuli Jiang Aijing Shan Matthew H. Bailey Kuan-lin Huang Sam Q. Sun Michael D. McLellan Beifang Niu Weiqing Wang Li Ding Guang Ning | 2018 | Cell Research2018，28，5： | 3 |
| 9 | Friction and Wear Properties of TiAl and Ti_2AlN/TiAl Composites at High Temperature显示文摘The high-temperature friction and wear properties of TiAl alloys and Ti2 AlN/TiAl composites(TTC) in contact with nickel-based superalloy were studied.The results showed that,at 800 and 1 000 ℃,the coefficient of the friction(COF) decreased with the increase of sliding velocity and the wear loss of the TTC decreased with the increase of volume fraction of Ti2 AlN.The wear mechanisms of the pairs are adhesive wear and the wear debris mainly comes from the contacting nickel-based superalloy.The intergranular fracture and the cracking of the phase boundary in the lamellar structure are the wear mode of TiAl alloy.The wear mode of TTC is phase boundary fracture and adhesive spalling.The abrasive resistance of TTC is slightly higher than that of TiAl alloy. | 孙东立 SUN Tao WANG Qing HAN Xiuli GUO Linlin | 2013 | Journal of Wuhan University of Technology(Materials Science)2013，28，5： | 3 |
| 10 | Experimental and mechanistic study on chemical looping combustion of caking coal显示文摘Under high-temperature batch fluidized bed conditions and by employing juye coal as the raw material,the present study determined the effects of the bed material,temperature,OC/C ratio,steam flow and oxygen carrier cycle on the chemical looping combustion of coal.In addition,the variations taking place in the surface functional groups of coal under different reaction times were investigated,and the variations achieved by the gas released under the pyrolysis and combustion of Juye coal were analyzed.As revealed from the results,the carbon conversion ratio and rate were elevated significantly,and the volume fraction of the outlet CO_(2)remained more than 92%under the oxygen carriers.The optimized reaction conditions to achieve the chemical looping combustion of Juye coal consisted of a temperature of 900℃,an OC/C ratio of 2,as well as a steam flow rate of 0.5 g·min^(-1).When the coal was undergoing the chemical looping combustion,volatiles primarily originated from the pyrolysis of aliphatic-CH_(3)and-CH_(2),and CO and H_(2)were largely generated from the gasification of aromatic carbon.In the CLC process,H_(2)O and CO_(2)began to separate out at 270℃,CH4 and tar began to precipitate at 370℃,and the amount of CO_(2)was continuously elevated with the rise of the temperature. | Xiuli Zhang Zhengdong Gao Yongzhuo Liu Yuanhao Hou Xiaoqing Sun Qingjie Guo | 2021 | Chinese Journal of Chemical Engineering2021，34，9： | 2 |
| 11 | Preparation and characterization of poly (vinylidene fluoride)/ Ti02 hybrid membranes显示文摘 | Weiying LI Xiuli SUN Chen WEN Hui LU Zhiwei WANG | 2013 | Frontiers of Environmental Science & Engineering2013，7，4： | 2 |
| 12 | Integrating Oxaliplatin with Highly Luminescent Carbon Dots: An Unprecedented Theranostic Agent for Personalized Medicine显示文摘 | Min Zheng Shi Liu Jing Li Dan Qu Haifeng Zhao Xingang Guan Xiuli Hu Zhigang Xie Xiabin Jing Zaicheng Sun | 2014 | Mater2014，，21： | 2 |
| 13 | Combining immune checkpoint blockade with ATP-based immunogenic cell death amplifier for cancer chemo-immunotherapy显示文摘Amplifying“eat me signal”during tumor immunogenic cell death(ICD)cascade is crucial for tumor immunotherapy.Inspired by the indispensable role of adenosine triphosphate(ATP,a necessary“eat me signal”for ICD),a versatile ICD amplifier was developed for chemotherapy-sensitized immunotherapy.Doxorubicin(DOX),ATP and ferrous ions(Fe^(2+))were co-assembled into nanosized amplifier(ADO-Fe)throughπ‒πstacking and coordination effect.Meanwhile,phenylboric acid-polyethylene glycol-phenylboric acid(PBA-PEG-PBA)was modified on the surface of ADO-Fe(denoted as PADO-Fe)by the virtue of d-ribose unit of ATP.PADO-Fe could display active targetability against tumor cells via sialic acid/PBA interaction.In acidic microenvironment,PBA-PEG-PBA would dissociate from amplifier.Moreover,high H_(2)O_(2)concentration would induce hydroxyl radical(·OH)and oxygen(O_(2))generation through Fenton reaction by Fe^(2+).DOX and ATP would be released from the amplifier,which could induce ICD effect and“ICD adjuvant”to amplify this process.Together with programmed death ligands 1(PD-L1)checkpoint blockade immunotherapy,PADO-Fe could not only activate immune response against primary tumor,but also strong abscopal effect against distant tumor.Our simple and multifunctional ICD amplifier opens a new window for enhancing ICD effect and immune checkpoint blockade therapy. | Jiulong Zhang Xiaoyan Sun Xiufeng Zhao Chunrong Yang Menghao Shi Benzhuo Zhang Haiyang Hu Mingxi Qiao Dawei Chen Xiuli Zhao | 2022 | Acta Pharmaceutica Sinica B2022，12，9： | 2 |
| 14 | High energy storage density and power density achieved simultaneously in NaNbO_(3)-based lead-free ceramics via antiferroelectricity enhancement显示文摘High-performance lead-free dielectric ceramics with simultaneously high energy storage density and power density are in high demanded for pulse power systems.To realize excellent energy-storage characteristics,a strategy to enhance antiferroelectricity and construct a local random field simultaneously was proposed in this study.Based on the above strategy,a series of(1-x)NaNbO_(3)-xBi(Ni_(1/2)Sn_(1/2))O3[xBNS,x=0.05,0.10,0.15,0.20,and 0.22]solid solutions were designed and fabricated.An ultrahigh energy storage density(Utotal)of 7.35 J/cm^(3),and recoverable energy density(Urec)of 5.00 J/cm^(3) were achieved in the 0.10BNS ceramics.In addition,an adequate stability of energy storage properties at a range of temperatures(20e140℃),frequencies(1e100 Hz),and fatigue test durations(1e1-10^(4) cycles)were realized in 0.10BNS ceramics.0.10BNS ceramics displayed a high current density of 1005 A/cm2,an ultrahigh power density of 100.5 MW/cm^(3,)and an ultrashort discharge time of 46.5 ns?This remarkable performance not only justified our strategy but also confirmed 0.10BNS ceramics as a promising candidate for energy storage. | Xiaoyan Dong Xu Li Xiuli Chen Hongyun Chen Congcong Sun Junpeng Shi Feihong Pang Huanfu Zhou | 2021 | Journal of Materiomics2021，7，3： | 2 |
| 15 | Defect-engineered Mn_(3)O_(4)/CNTs composites enhancing reaction kinetics for zinc-ions storage performance显示文摘The designing of reasonable nanocomposite materials and proper introduction of defect engineering are of great significance for the improvement of the poor electronic conductivity and slow reaction kinetics of manganese-based compounds. Herein, we report manganese-deficient Mn_(3)O_(4) nanoparticles which grow in-situ on highly conductive carbon nanotubes(CNTs)(denoted as DMOC) as an advanced cathode material for aqueous rechargeable zinc-ion batteries(RAZIBs). According to experimental and calculation results, the DMOC cathode integrates the advantages of enriched Mn defects and small particle size. These features not only enhance electronic conductivity but also create more active site and contribute to fast reaction kinetics. Moreover, the structure of DMOC is maintained during the charging and discharging process, thus benefiting for excellent cycle stability. As a result, the DMOC electrode delivers a high specific capacity of 420.6 m A h g^(-1) at 0.1 A g^(-1) and an excellent cycle life of 2800 cycles at 2.0 A g^(-1) with a high-capacity retention of 84.1%. In addition, the soft-packaged battery assembled with DMOC cathode exhibits long cycle life and high energy density of 146.3 Wh kg^(-1) at 1.0 A g^(-1) . The results are beneficial for the development of Zn/Mn_(3)O_(4) battery for practical energy storage. | Xiuli Guo Hao Sun Chunguang Li Siqi Zhang Zhenhua Li Xiangyan Hou Xiaobo Chen Jingyao Liu Zhan Shi Shouhua Feng | 2022 | Journal of Energy Chemistry2022，31，5： | 1 |
| 16 | Twining and dynamic precipitation upon hot compression of a Mg-Gd-Y-Nd-Gr alloy 显示文摘 | Hou Xiuli Cao Zhanyi Sun Xu | 2012 | Journal of Alloys and Compounds2012，525，： | 1 |
| 17 | Fabrication of in situ Ti_2AlN/TiAl Composites by Reaction Hot Pressing and Their Properties显示文摘Ti2AlN/TiAl composites with different volume fractions of reinforcement were successfully fabricated by hot-pressing sintering method(reaction hot pressing) using Ti, Al and TiN powders as starting materials. The synthesis process includes four stages: first, the reactions between Al and Ti powers and between Al and TiN powders respectively occur and result in TiAl3 phase; secondly, Al powders in the sample are exhausted; the remaining Ti cores react with TiAl3 layer to form Ti-Al intermetallics; moreover, a few Ti2AlN particles precipitate from the TiAl3 phase; thirdly, Ti-Al intermetallics react with the remaining Ti cores to form Ti3Al and TiAl phases. TiAl phase and original TiN powers are in direct contact each other; finally, the residual TiN powers react with TiAl phase and result in a plenty of Ti2AlN phase. Compared with TiAl matrix, the hardness, elastic modulus and high-temperature compressive strength of Ti2AlN/TiAl composite are improved obviously and they are all enhanced with increasing the volume fraction of Ti2AlN phase. | 孙东立 SUN Tao WANG Qing HAN Xiuli GUO Qiang WU Gaohui | 2014 | Journal of Wuhan University of Technology(Materials Science)2014，29，1： | 1 |
| 18 | Hot deformation behavior of a near alpha titanium alloy with/without thermal hydrogen processing显示文摘The true stress-true strain curves of Ti-6Al-2Zr-1Mo-1V alloy with hydrogen were obtained by hot compression test.The microstructures of the alloy before and after thermo-compression were observed.The apparent activation energies of deformation were calculated for the alloy with and without hydrogen.The behavior and mechanism of deformation for hydrogenated Ti-6Al-2Zr-1Mo-1V alloy at high temperature were analyzed.The relationship between hydrogenation time and hydrogen content at 800 ℃ can be expressed as the equation:CH(t)=1.2-1.2exp(-t/120).The true stress-true strain curves of hot compression for Ti-6Al-2Zr-1Mo-1V alloy with hydrogen first move down and then move up as hydrogen content increases.Appropriate hydrogen content can reduce the peak of flow stress to minimal value.The apparent activation energies of deformation of the alloy with 0.47% hydrogen content and without hydrogen were calculated as 140 kJ·mol-1 and 390 kJ·mol-1,respectively,at 800 ℃ and at strain rate 8.3×10-4 s-1.The apparent activation energy of deformation increases when the strain rate enhances from 8.3×10-4 s-1 to 8.3×10-2 s-1. | Qing WANG Dongli SUN Xiuli HAN Weigong WANG | 2010 | Acta Metallurgica Sinica(English Letters)2010，23，2： | 1 |
| 19 | Crystallization behavior of asymmetric PLLA/PDLA blends 显示文摘 | SUN Jingru YU Haiyang ZHUANG Xiuli | 2011 | J Phys Chem B2011，115，12： | 1 |
| 20 | Design and operation of a CFB gasification and power generation system for rice husk显示文摘 | Yin Xiuli Wu Chuangzhi Sun Pengzheng | 2002 | Biomass and Bioenergy2002，23，3： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员