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| 1 | Transcranial direct current stimulation in psychiatric disorders显示文摘The interest in non-invasive brain stimulation techniques is increasing in recent years. Among these techniques, transcranial direct current stimulation(t DCS) has been the subject of great interest among researchers because of its easiness to use, low cost, benign profile of side effects and encouraging results of research in the field. This interest has generated several studies and randomized clinical trials, particularly in psychiatry. In this review, we provide a summary of the development of the technique and its mechanism of action as well as a review of the methodological aspects of randomized clinical trials in psychiatry, including studies in affective disorders, schizophrenia, obsessive compulsive disorder, child psychiatry and substance use disorder. Finally,we provide an overview of t DCS use in cognitive enhancement as well as a discussion regarding its clinical use and regulatory and ethical issues. Although many promising results regarding t DCS efficacy were described, the total number of studies is still low, highlighting the need of further studies aiming to replicate these findings in larger samples as to provide a definite picture regarding t DCS efficacy in psychiatry. | Gabriel Tortella Roberta Casati Luana V M Aparicio Antonio Mantovani Natasha Senco Giordano D’Urso Jerome Brunelin Fabiana Guarienti Priscila Mara Lorencini Selingardi Débora Muszkat Bernardo de Sampaio Pereira Junior Leandro Valiengo Adriano H Moffa Marcel Simis Lucas Borrione André R Brunoni | 2015 | World Journal of Psychiatry2015，5，1： | 6 |
| 2 | Cellular Serpents and Dreaming Spires:New Frontiers in Arginine and Pyrimidine Biology显示文摘The International Conference on Arginine and Pyrimidines(ICAP)had its origin as an arginine workshop organised by a group of microbiologists led by Werner Maas in 1972(Rubio,2003).The shared requirement of carbamoyl phosphate in both arginine and pyrimidine metabolism led to a natural | Gabriel N.Aughey mr Y.Tastan Ji-Long Liu | 2014 | Journal of Genetics and Genomics2014，41，10： | 2 |
| 3 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 4 | G-DBSCAN:A GPU accelerated algorithm for density-based clustering显示文摘 | Guilherme A Gabriel R Daniel M | 2013 | Procedia Computer Science2013，18，： | 1 |
| 5 | Prediction of firmness and soluble solids content of blueberries using hyperspectral reflectance imaging显示文摘 | GABRIEL A L LU R F AGUILERA J M | 2013 | Journal of Food Engineering2013，115，： | 1 |
| 6 | Mapping small elevation changes over large areas: Dif- ferential radar interferometry显示文摘 | GABRIEL A K GOLDSTEIN R M ZEBKER H A | 1989 | Journal of Geophysi- cal Research1989，94，7： | 1 |
| 7 | Crossed Orbit Inter ferometry: Theory and Experimental Results from SIR B 显示文摘 | GABRIEl A K GOLDSTEIN R M | 1988 | International Journal of Remote Sensing1988，9，5： | 1 |
| 8 | High dynamic range image display with halo and clipping prevention显示文摘 | GABRIELE G STEFANO M GIOVANNI R | 2011 | IEEE Transactions on Image Processing2011，20，5： | 1 |
| 9 | Hyperthermia and radiation therapy for inoperable or recurrent parotid carcinoma显示文摘 | Gabriele P Amichetti M Orecchia R | 1995 | Cancer1995，75，4： | 1 |
| 10 | The influence of layered compounds on the properties of starch/layered compound composites 显示文摘 | Helena - M Wilhelm Maria - R Sierakowski Gabriel P Souza | 2003 | Polymer International2003，52，： | 1 |
| 11 | Renal impairment and heart failure with preserved ejection fraction early post-myocardial infarction显示文摘AIM:To study if impaired renal function is associated with increased risk of peri-infarct heart failure (HF) in patients with preserved ejection fraction (EF).METHODS:Patients with occluded infarct-related arteries (IRAs) between 1 to 28 d after myocardial infarction (MI) were grouped into chronic kidney disease (CKD) stages based on estimated glomerular filtration rate (eGFR).Rates of early post-MI HF were compared among eGFR groups.Logistic regression was used to explore independent predictors of HF.RESULTS:Reduced eGFR was present in 71.1% of 2160 patients,with significant renal impairment (eGFR < 60 mL/min every 1.73 m2) in 14.8%.The prevalence of HF was higher with worsening renal function:15.5%,17.8% and 29.4% in patients with CKD stages 1,2 and 3 or 4,respectively (P < 0.0001),despite a small absolute difference in mean EF across eGFR groups:48.2 ± 10.0,47.9 ± 11.3 and 46.2 ± 12.1,respectively (P=0.02).The prevalence of HF was again higher with worsening renal function among patients with preserved EF:10.1%,13.6% and 23.6% (P < 0.0001),but this relationship was not significant among patients with depressed EF:27.1%,26.2% and 37.9% (P= 0.071).Moreover,eGFR was an independent correlate of HF in patients with preserved EF (P=0.003) but not in patients with depressed EF (P=0.181).CONCLUSION:A significant proportion of post-MI patients with occluded IRAs have impaired renal function.Impaired renal function was associated with an increased rate of early post-MI HF,the association being strongest in patients with preserved EF.These findings have implications for management of peri-infarct HF. | Vinod Jorapur Gervasio A Lamas Zygmunt P Sadowski Harmony R Reynolds Antonio C Carvalho Christopher E Buller James M Rankin Jean Renkin Philippe Gabriel Steg Harvey D White Carlos Vozzi Eduardo Balcells Michael Ragosta C Edwin Martin Vankeepuram S Srinivas William W Wharton III Staci Abramsky Ana C Mon Shari S Kronsberg Judith S Hochman | 2010 | World Journal of Cardiology2010，2，1： | 1 |
| 12 | Crossed orbit interferometry, theory and experimental results from SIR-B 显示文摘 | GABRIEL A K GOLDSTEIN R M | 1988 | International Journal of Remote Sensing1988，9，5： | 1 |
| 13 | Experimental and analytical investigation of thermal coating effectiveness for 3 m3 LPG tanks engulfed by fire显示文摘 | GABRIELE L MENSO M JOHAN R | 2009 | Journal of Hazardous Materials2009，161，： | 1 |
| 14 | Crossed Orbit Interferometry: Theory and Experimental Results from SIR-B显示文摘 | GABRIEL A K GOLDSTEIN R M | 1988 | International Journal of Remote Sensing1988，9，5： | 1 |
| 15 | Learning about Carbon Capture and Storage : Changing Stakeholder Perceptions with Expert Information 显示文摘 | Jennie C S Jeffrey B Gabriel M R | 2009 | Energy Procedia2009，，1： | 1 |
| 16 | A param eterization for the threshold shear velocity to initiate deflation of dry and wet sediment 显示文摘 | Comelis W M Gabriels D Hartmann R | 2004 | Geomorphology2004，9，： | 1 |
| 17 | Mapping Small E1 evation Changes over Large Areas: Differential Radar Interferometry显示文摘 | Gabriel A K Goldstein R M Zebker H A | 1989 | Journal of Geophysical Research1989，，： | 1 |
| 18 | Crossed orbit interferometry:Theory and experimental results from SIR-B 显示文摘 | Gabriel A K R M Goldstein | 1988 | Int J Remote Sensing1988，9，8： | 1 |
| 19 | Thermo me-chanical and rheological asphalt modification using styrenebutadiene triblock copolymers with different microstructure显示文摘 | Gabriel H G Medina E M Sanchez R | 2006 | Energy and Fuels2006，20，6： | 1 |
| 20 | Electrophy siologic abnormalities of the hippocampus in the pilocarpine/cycloheximide model of chronic spontaneous seizures显示文摘 | Longo B M Sanabria E R Gabriel S | 2002 | J Epilepsia2002，43，5： | 1 |
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