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| 1 | Interaction Between Variations in Dopamine D2 and Serotonin 2A Receptor is Associated with Short-Term Response to Antipsychotics in Schizophrenia显示文摘Dear Editor,Schizophrenia is a chronic and debilitating brain disorder,which has a strong genetic component with heritability ranging from 66%to 85%[1,2].Currently,antipsychotic drugs remain the most effective treatment for the psychotic symptoms of schizophrenia[3].Because of the severe sideeffects of first-generation antipsychotics(FGAs),secondgeneration antipsychotics(SGAs)have become more widely used in the treatment of schizophrenia. | Liansheng Zhao Huijuan Wang Yamin Zhang Jinxue Wei Peiyan Ni Hongyan Ren Gang Li Qiang Wang Gavin P Reynolds Weihua Yue Wei Deng Hao Yan Liwen Tan Qi Chen Guigang Yang Tianlan Lu Lifang Wang Fuquan Zhang Jianli Yang Keqing Li Luxian Lv Qingrong Tan Yinfei Li Hua Yu Hongyan Zhang Xin Ma Fude Yang Lingjiang Li Chuanyue Wang Huiyao Wang Xiaojing Li Wanjun Guo Xun Hu Yang Tian Xiaohong Ma Jeremy Coid Dai Zhang Chao Chen Tao Li Chinese Antipsychotics Pharmacogenomics Consortium | 2019 | Neuroscience Bulletin2019，35，6： | 3 |
| 2 | Reference surface element modeling of composite plate/shell delamination buckling and postbuckling 显示文摘 | ZHU Ju-fen ZHENG Gang HOWSON W P | 2003 | Compos Struct2003，61，3： | 2 |
| 3 | Rapid phenotypic evolution with shallow genomic differentiation during early stages of high elevation adaptation in Eurasian Tree Sparrows显示文摘Known as the‘third polar region’,the Qinghai-Tibet Plateau represents one of the harshest highland environments in the world and yet a number of organisms thrive there.Previous studies of birds,animals and humans have focused on well-differentiated populations in later stages of phenotypic divergence.The adaptive processes during the initial phase of highland adaptation remain poorly understood.We studied a human commensal,the Eurasian Tree Sparrow,which has followed human agriculture to the Qinghai-Tibet Plateau.Despite strong phenotypic differentiation at multiple levels,in particular in muscle-related phenotypes,highland and lowland populations show shallow genomic divergence and the colonization event occurred within the past few thousand years.In a one-month acclimation experiment investigating phenotypic plasticity,we exposed adult lowland tree sparrows to a hypoxic environment and did not observe muscle changes.Through population genetic analyses,we identified a signature of polygenic adaptation,whereby shifts in allele frequencies are spread across multiple loci,many of which are associated with muscle-related processes.Our results reveal a case of positive selection in which polygenic adaptation appears to drive rapid phenotypic evolution,shedding light on early stages of adaptive evolution to a novel environment. | Yanhua Qu Chunhai Chen Ying Xiong Huishang She Yong E Zhang Yalin Cheng Shane DuBay Dongming Li Per G P Ericson Yan Hao Hongyuan Wang Hongfeng Zhao Gang Song Hailin Zhang Ting Yang Chi Zhang Liping Liang Tianyu Wu Jinyang Zhao Qiang Gao Weiwei Zhai Fumin Lei | 2020 | National Science Review2020，7，1： | 2 |
| 4 | Diagnosis and treatment oftracheobronchial foreign bodies in 1 024 children显示文摘 | Gang W Zhengxia P Hongbo L | 2012 | J PediatrSurg2012，47，11： | 1 |
| 5 | Particle concentration effect and adsorption reversibility显示文摘 | PAN Gang LISS P S KROM M D | 1999 | Colloids and Surface A1999，151，12： | 1 |
| 6 | Quasi-C-Ehresmann semigroups and their subclasses显示文摘 | Gang Li Y Q Guo K P Shum | 2005 | Semigroup Forum2005，70，： | 1 |
| 7 | Indirect chemiluminescence detection for capillary zone electrophoresis of monoamines and catechol using luminol-K3system显示文摘 | YONG Gang H Xinxin L Zhitao P | 2005 | Journal of Chromatography A2005，，1091： | 1 |
| 8 | Fully integrated CMOS power amplifier with efficiency enhancement at power back-off显示文摘 | Liu Gang Haldi P | 2008 | IEEE Journal of Solid-State Circuits2008，，3： | 1 |
| 9 | Fisher information in hybrid censored data显示文摘 | Sangun P Balakrishnan N ZHENG Gang | 2008 | Statistics and Probability Letters2008，78，： | 1 |
| 10 | Midorine appears to be safe and effective for dioeysis-induced hypotension:a systematic review 显示文摘 | PRAKASH S GANG AXHELDENHEIM A P HOUSE A A | 2004 | Nephrol Dial Transplant2004，19，10： | 1 |
| 11 | On left C-Ehresmann cyber groups显示文摘 | Gang Li K P Shum | 2005 | Advances in Algebra and Analysis2005，1，： | 1 |
| 12 | Bile salt biotransformations by human intestinal bacteria显示文摘 | Ridlon J M gang D J Hylemon P B | 2006 | J Lipid Res2006，47，2： | 1 |
| 13 | Analysis of low temperature solar thermal e- lectric generation using regenerative organic Rankine cycle 显示文摘 | Gang P Jing L Jie J | 2010 | Applied Thermal Engineering2010，30，89： | 1 |
| 14 | Compressive sens- ing with chaotic sequenee显示文摘 | LEI Y BARBOT J P GANG Z | 2010 | IEEE Signal Processing Letters2010，17，8： | 1 |
| 15 | Influence of the heating rate on the microstructure and on macroscopic properties of sol - gel SnO2: Sb coatings显示文摘 | Gang D Gasparro G | 1998 | JournalofSol - Gel Science and Technology1998，13，： | 1 |
| 16 | Cardiac surgery in Germany during 1997 显示文摘 | Kalmar P ln'gang E | 1998 | Thorac Cardiovasc Surg1998，46，5： | 1 |
| 17 | Linear response theory in stochastic resonance 显示文摘 | M I Dykman H Hakenb Gang Hud D G Luchinskya R Mannellaa P V E McClintocka C Z Ninggb N D Steina N G Stockse | 1993 | Physics Letters A1993，180，45： | 1 |
| 18 | DNA vaccines expressing B and T cell epitopes can protect mice from FMDV infection in the absence of specific humoral responses 显示文摘 | Borrego B Fernandez-Pacheco P Ganges L | 2006 | Vaccine2006，24，18： | 1 |
| 19 | Adaptive control of plants with unknown dead-zones显示文摘 | Gang T Kokotovic P V | 1994 | IEEE Trans on Automatic Control1994，39，1： | 1 |
| 20 | An on-line algorithm for creating self-organizing fuzzy neural net- works 显示文摘 | GANG L GIRIJESH P THOMAS M M | 2004 | Neural Networks2004，17，10： | 1 |
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