维普中文期刊产品整合服务
62篇 您的检索式:作者名="Garg P C"
    题名 作者 年代 出处 被引量
1Combination immunotherapy with Survivin and luteinizing hormone-releasing hormone fusion protein in murine breast cancer model显示文摘AIM To investigate the therapeutic potential of two recombinant proteins, Survivin and luteinizing hormone-releasing hormone (LHRH) fusion protein [LHRH(6 leu)-LTB] for immunotherapy of breast cancer.METHODS Murine 4 T-1 breast cancer model was used to evaluate the efficacy of recombinant proteins in vivo. Twenty four Balb/c mice were divided into 4 groups of 6 mice each. Recombinant Survivin and LHRH fusion protein, alone or in combination, were administered along with immunomodulator Mycobacterium indicus pranii (MIP) in Balb/c mice. Unimmunized or control group mice were administered with phosphate buffer saline. Each group was then challenged with syngeneic 4 T-1 cells to induce the growth of breast tumor. Tumor growth was monitored to evaluate the efficacy of immune-response in preventing the growth of cancer cells.RESULTS Preventive immunization with 20 μg recombinant Survivin and MIP was effective in suppressing growth of 4 T-1 mouse model of breast cancer (P = 0.04) but 50 μg dose was ineffective in suppressing tumor growth. However, combination of Survivin and LHRH fusion protein was more effective in suppressing tumor growth (P = 0.02) as well as metastasis in vivo in comparison to LHRH fusion protein as vaccine antigen alone.CONCLUSION Recombinant Survivin and MIP suppress tumor growth significantly. Combining LHRH fusion protein with Survivin and MIP enhances tumor suppressive effects marginally which provides evidence for recombinant Survivin and LHRH fusion protein as candidates for translating the combination cancer immunotherapy approaches.Himani Garg Rohit Singh Hada Jagdish C Gupta G P Talwar Shweta Dubey 2018World Journal of Clinical Oncology2018,9,8:2
2Laparoscopic repair of perforatedpeptic ulcer with delayed presentation 显示文摘Vaidya B B Garg C P Shah J B 20097 Laparoendosc AdvSurg Tech A2009,19,2:1
3An experimental study on the effect of ultrasonication on viscosity and heat transfer performance of multi-wall carbonnanotube-based aqueous nanofluids 显示文摘Garg P Alvarado J L Marsh C 2009International Journal of Heat and Mass Transfer2009,52,21:1
4A study of collaboration in laser science and technology 显示文摘GARG K C PADHI P 2001Scientometrics2001,51,2:1
5'Optimal Growth with depletable Resources'显示文摘Garg P C Sweeney J L 1978Resources and Energy1978,,1:1
6Regulation of miR-200 family microRNAs and ZEB transcription factors in ovarian cancer:Evidence supporting a mesothelial-toepithelial transition显示文摘Bendoraite A Knouf E C Garg K S Parkin R K Kroh E M O'Briant K C Ventura A P Godwin A K Karlan B Y Drescher C W and others 0,,01:1
7The NIH human microbiome project显示文摘NIH HMP Working Group Peterson J Garges S Giovanni M McInnes P Wang L Schloss JA Bonazzi V McEwen JE Wetterstrand KA Deal C Baker CC Di Francesco V Howcroft TK Karp RW Lunsford RD Wellington CR Belachew T Wright M Giblin C David H Mills M Salomon R Mullins C Akolkar B Begg L Davis C Grandison L Humble M Khalsa J Little AR Peavy H Pontzer C Portnoy M Sayre MH Starke-Reed P Zakhari S Read J Watson B Guyer M 2009Genome Res2009,19,12:1
82010, Antimicrobial and phyto- chemical studies of fresh ripe pulp and dried unripe pulp of Mangiem indica (AMCHUR)显示文摘Gupta C Garg A P Gupta S 2010Middle-East Journal of Scientific Research2010,5,2:1
9Vermicomposting of sugar industry waste(press mud)mixed with cow dung employing an epigeic earthworm Eisenia fetida显示文摘Sangwan P Kaushik C P Garg V K 2010Waste Management&Research2010,28,1:1
10Impact of SERC's funding on research in chemical sciences 显示文摘Jain A Garg K C Sharma P 1998Scientometrics1998,41,3:1
11Biobhaehing effect of Streptomyces thermoviolaceus mase preparations on birchwood kraft pulp显示文摘Garg A P Mocathy A J Roberts J C 1996Enzyme Microbial Technol1996,18,:1
12Lack of association between migraine headache and patent foramen ovale:Results of a case-control study显示文摘GARG P SERVOSS S J WU J C 2010Circulation2010,121,:1
13Caveolin-1 expression is associated with high-grade bladder cancer显示文摘Rajjayabun P H Garg S Durkan G C 2001Urology2001,58,5:1
14An ex- perimental study on the effect of uhrasonication on viscosi- ty and heat transfer performance of multi-wall carbon nanotube-based aqueous nanofluids显示文摘GARG P ALVARADO J L MARSH C 2009International Jour- nal of Heat and Mass Transfer2009,52,2122:1
15Optimal growth with depletable resources显示文摘Garg P C Sweeney J L 1978Resources and Energy1978,1,1:1
16Impact of SERC's funding on research in chemical sciences显示文摘Jain A Garg K C Sharma P 1998Scientometrics1998,41,3:1
17Design curves for conventional solar air heaters 显示文摘Choudhury C Chauhan P M Garg H P 1995Renewable Energy1995,6,7:1
18Efficacy of laparoscopy in complicated appendicitis显示文摘Garg C P Vaidya B B Chengalath M M 2009Int J Surg2009,7,3:1
19Optimal growth with deletable resources显示文摘Garg P C Sweeney J L 1978Res Energy1978,1,:1
20Patent statistics as indicators of competition an analysis of patenting in biotechnology显示文摘BANERJEE P GUPTA B M GARG K C 2000Scientometrics2000,47,:1
返回顶部 每页显示:
共4页 首页 上一页 第1页 下一页 末页 /4 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费