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| 1 | Landscape of DILI-related adverse drug reaction in China Mainland显示文摘Drug-induced liver injury(DILI)is a type of bizarre adverse drug reaction(ADR)damaging liver(L-ADR)which may lead to substantial hospitalizations and mortality.Due to the general low incidence,detection of L-ADR remains an unsolved public health challenge.Therefore,we used the data of 6.673 million of ADR reports from January 1st,2012 to December 31st,2016 in China National ADR Monitoring System to establish a new database of L-ADR reports for future investigation.Results showed that totally 114,357 ADR reports were retrieved by keywords searching of liver-related injuries from the original heterogeneous system.By cleaning and standardizing the data fields by the dictionary of synonyms and English translation,we resulted 94,593 ADR records reported to liver injury and then created a new database ready for computer mining.The reporting status of L-ADR showed a persistent 1.62-fold change over the past five years.The national population-adjusted reporting numbers of L-ADR manifested an upward trend with age increasing and more evident in men.The annual reporting rate of L-ADR in age group over 80 years old strikingly exceeded the annual DILI incidence rate in general population,despite known underreporting situation in spontaneous ADR reporting system.The percentage of herbal and traditional medicines(H/TM)L-ADR reports in the whole number was 4.5%,while 80.60%of the H/TM reports were new findings.There was great geographical disparity of reported agents,i.e.more cardiovascular and antineoplastic agents were reported in higher socio-demographic index(SDI)regions and more antimicrobials,especially antitubercular agents,were reported in lower SDI regions.In conclusion,this study presented a large-scale,unbiased,unified,and computer-minable L-ADR database for further investigation.Age-,sex-and SDI-related risks of L-ADR incidence warrant to emphasize the precise pharmacovigilance policies within China or other regions in the world. | Jiabo Wang Haibo Song Feilin Ge Peng Xiong Jing Jing Tingting He Yuming Guo Zhuo Shi Chao Zhou Zixin Han Yanzhong Han Ming Niu Zhaofang Bai Guangbin Luo Chuanyong Shen Xiaohe Xiao | 2022 | Acta Pharmaceutica Sinica B2022，12，12： | 12 |
| 2 | The template preparation and characterization of three new shapes of titania nanometer-array systems显示文摘A two-step anodization process was used to prepare highly ordered porous anodic alu- mina template (PAA). The template method was combined with the sol-electrophoresis deposition and sol-gel method to synthesize three types of nano- meter-array systems. The titania nano-arrays have a high specific surface area. The sol-gel template method was also applied to prepare the rod-shaped titania nanowire-arrays. The diameter of titania nanometer-array is about 50 nm; the length is about 20 μm; and the distance of neighboring two nanowires is about 100 nm. Through controlling the pore depth of the template, the membrane with peri- odical modulating titania nanodots was prepared. The diameter of the nanodots on the membrane surface was about 75 nm and the dot distance was about 100 nm. Also a compact structure has been found on the back face of the membrane. The sol-electrophoresis template method was used to prepare the nanowire-array system with the shape of string of candied haws. The diameter of nanowires was about 75 nm and the length was about 20 μm. The periodic concave-convex structures were found in each nanowire and the shape looked like string of candied haws. The three types of nano-array systems have a high specific surface area. It can be predicted that this type of surface modulating array system will have new properties and effects that are different from those of common membranes, nanodots and nanowires. | TIAN Yuming XU Mingxia LIU Xiangzhi GE Lei | 2006 | Chinese Science Bulletin2006，51，12： | 4 |
| 3 | Catalytic Oxidative Desulfurization of Gasoline Using Vanadium(V)-substituted Polyoxometalate/H_2O_2/Ionic Liquid Emulsion System显示文摘Aiming at deep desulfurization of gasoline,three amphiphilic catalysts [C18H37N(CH3)3]3+x [PMo12-xVxO40](x=1,2,or 3) were prepared and characterized.The amphiphilic vanadium(V)-substituted polyoxometalates were dissolved in water-immiscible ionic liquid([Bmim]PF6),forming a H2O2-in-[Bmim]PF6 emulsion desulfurization system with 30 m% H2O2 serving as the oxidant.The catalytic oxidation of sulfur-containing model oil has been studied in detail under various reaction conditions using this system.The ionic liquid emulsion system showed high catalytic oxidative activity in the treatment of commodity gasoline.Furthermore,the mechanism of catalytic oxidative desulfurization was also elaborated. | Ge Jianhua Zhou Yuming Yang Yong Xue Mengwei | 2012 | China Petroleum Processing & Petrochemical Technology2012，14，1： | 2 |
| 4 | A Distributed Decision Making Method in Cognitive Radio Networks for Spectrum Management显示文摘 | GE Yuming SUN Yi LU Shan Eryk Dutkiewicz | 2010 | Chinese Journal of Electronics2010，19，2： | 1 |
| 5 | Diabetes mellitus and risk of gastric cancer: a systematic review and meta-analysis of observational studies显示文摘 | Zhenming Ge Qiwen Ben Junbo Qian Yamin Wang Yuming Li | 2011 | European Journal of Gastroenterology & Hepatology2011，，12： | 1 |
| 6 | Dynamic optimization model for cooperative downloading strategy of VANET显示文摘 | Liu Jianhang Ge Yuming Bi Jingping | 2013 | Journal of Internet Technology2013，14，6： | 1 |
| 7 | The existence of multiple positive solutions to boundary value problems of nonlinear delay differential equations with countably many sigularities on infinite interval显示文摘 | Wei Yuming Patricia J Y Wong Ge W G | 2010 | Journal of Computatioral and Applied Mathematics2010，233，： | 1 |
| 8 | Energy-ef- ficiency optimization for MIMO-OFDM mobile multimedia communication systems with QoS constraints 显示文摘 | Ge Xiaohu Huang Xi Wang Yuming | 2014 | IEEE Transaction on Vehicular Technology2014，63，5： | 1 |
| 9 | Nickel-decorated TiO2 nanotube arrays as a self-supporting cathode for lithium-sulfur batteries显示文摘Lithium-sulfur batteries are considered to be one of the strong competitors to replace lithium-ion batteries due to their large energy density.However,the dissolution of discharge intermediate products to the electrolyte,the volume change and poor electric conductivity of sulfur greatly limit their further commercialization.Herein,we proposed a self-supporting cathode of nickel-decorated TiO2 nanotube arrays(TiO2 NTs@Ni)prepared by an anodization and electrodeposition method.The TiO2 NTs with large specific surface area provide abundant reaction space and fast transmission channels for ions and electrons.Moreover,the introduction of nickel can enhance the electric conductivity and the polysulfide adsorption ability of the cathode.As a result,the TiO2 NTs@Ni-S electrode exhibits significant improvement in cycling and rate performance over TiO2 NTs,and the discharge capacity of the cathode maintains 719 mA·h·g−1 after 100 cycles at 0.1 C. | Yuming Chen Wenhao Tang Jingru Ma Ben Ge Xiangliang Wang Yufen Wang Pengfei Ren Ruiping Liu | 2020 | Frontiers of Materials Science2020，14，3： | 0 |
| 10 | MULTIPLE POSITIVE SOLUTIONS TO BOUNDARY VALUE PROBLEMS OF DELAY DIFFERENTIAL EQUATIONS WITH DENUMBERABLE SINGULARITIES ON INFINITE INTERVAL显示文摘This paper deals with the existence of denumberable positive solutions to boundary value problems of delay differential equations with denumberable singularities on infinite intervals. By the fixed-point index theory and a new fixed-point theorem in cones, the existence of denumberable positive solutions is obtained under some suitable growth conditions imposed on the nonlinear term. | Yuming Wei, Yanqiu Tang (School of Mathematical Science, Guangxi Normal University, Guilin 541004, Guangxi) Weigao Ge (Dept. of Math., Beijing Institute of Technology, Beijing 100081) | 2011 | Annals of Differential Equations2011，27，2： | 0 |
| 11 | Synthesis of π-extended dibenzo[d,k]ullazines by a palladium-catalyzed double annulation using arynes显示文摘An efficient Pd-catalyzed double annulation reaction of 1-(2,6-dibro mophenyl)-1 H-pyrroles with arynes is developed to synthesizeπ-extended dibenzo[d,k]ullazines in good to excellent yields.For the first time,the parent dibenzo[d,k]ullazine core is obtained and characterized. | Deping Wang Yan Liu Linhua Wang Hu Cheng Yuming Zhang Ge Gao | 2021 | Chinese Chemical Letters2021，32，4： | 0 |
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