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| 1 | Towards a global One Health index: a potential assessment tool for One Health performance显示文摘Background:A One Health approach has been increasingly mainstreamed by the international community, as it provides for holistic thinking in recognizing the close links and inter-dependence of the health of humans, animals and the environment. However, the dearth of real-world evidence has hampered application of a One Health approach in shaping policies and practice. This study proposes the development of a potential evaluation tool for One Health performance, in order to contribute to the scientific measurement of One Health approach and the identification of gaps where One Health capacity building is most urgently needed.Methods:We describe five steps towards a global One Health index (GOHI), including (i) framework formulation;(ii) indicator selection;(iii) database building;(iv) weight determination;and (v) GOHI scores calculation. A cell-like framework for GOHI is proposed, which comprises an external drivers index (EDI), an intrinsic drivers index (IDI) and a core drivers index (CDI). We construct the indicator scheme for GOHI based on this framework after multiple rounds of panel discussions with our expert advisory committee. A fuzzy analytical hierarchy process is adopted to determine the weights for each of the indicators.Results:The weighted indicator scheme of GOHI comprises three first-level indicators, 13 second-level indicators, and 57 third-level indicators. According to the pilot analysis based on the data from more than 200 countries/territories the GOHI scores overall are far from ideal (the highest score of 65.0 out of a maximum score of 100), and we found considerable variations among different countries/territories (31.8–65.0). The results from the pilot analysis are consistent with the results from a literature review, which suggests that a GOHI as a potential tool for the assessment of One Health performance might be feasible.Conclusions:GOHI—subject to rigorous validation—would represent the world’s first evaluation tool that constructs the conceptual framework from a holistic perspective of One Health. Future application of GOHI might promote a common understanding of a strong One Health approach and provide reference for promoting effective measures to strengthen One Health capacity building. With further adaptations under various scenarios, GOHI, along with its technical protocols and databases, will be updated regularly to address current technical limitations, and capture new knowledge. | Xiao-Xi Zhang Jing-Shu Liu Le-Fei Han Shang Xia Shi-Zhu Li Odel YLi Kokouvi Kassegne Min Li Kun Yin Qin-Qin Hu Le-Shan Xiu Yong-Zhang Zhu Liang-Yu Huang Xiang-Cheng Wang Yi Zhang Han-Qing Zhao Jing-Xian Yin Tian-Ge Jiang Qin Li Si-Wei Fei Si-Yu Gu Fu-Min Chen Nan Zhou Zi-Le Cheng Yi Xie Hui-Min Li Jin Chen Zhao-Yu Guo Jia-Xin Feng Lin Ai Jing-Bo Xue Qian Ye Liz Grant Jun-Xia Song Geoff Simm Jürg Utzinger Xiao-Kui Guo Xiao-Nong Zhou | 2022 | Infectious Diseases of Poverty2022，11，3： | 3 |
| 2 | Efficacy, safety and tolerability of bosentan in Chinese patients with pulmonary arterial hypertension显示文摘 | Zhi-Cheng Jing Geoff Strange Xian-Yang Zhu Da-Xin Zhou Jie-Yan Shen Hong Gu Zhen-Kun Yang Xin Pan Mei-Xiang Xiang Hua Yao Dong-Bao Zhao Brad S. Dalton Zhuo-Li Zhang Yong Wang Xian-Sheng Cheng Yue-Jin Yang | 2010 | Journal of Heart and Lung Transplantation2010，，2： | 1 |
| 3 | Partial carbon per- mits allocation of potential emission trading scheme in Aus- tralian electricity market 显示文摘 | ZHOU Xun GEOFF J ARIEL L | 2010 | IEEE Transactions on Power Systems2010，25，1： | 1 |
| 4 | Hyperhomocysteinemia and its role in the development of atherosclerosis显示文摘 | A.B. Lawrence de Koning Geoff H. Werstuck Ji Zhou Richard C. Austin | 2003 | Clinical Biochemistry2003，，6： | 1 |
| 5 | Association of multiple cellular stress pathways with accelerated atherosclerosis in hyperhomocysteinemic apolipoprotein E-deficient mice显示文摘 | Zhou MD Geoff Werstuck Sarka Lhotak | 2004 | Circulation2004，13，7： | 1 |
| 6 | Electro-Fenton method for the removal of methyl red in an efficient electrochemical system显示文摘 | Minghua Zhou Qinghong Yu Lecheng Lei Geoff Barton | 2007 | Separation and Purification Technology2007，，2： | 1 |
| 7 | Association of Multiple Cellular Stress Pathways With Accelerated Atherosclerosis in Hyperhomocysteinemic Apolipoprotein E-Deficient Mice显示文摘 | Ji Zhou Geoff H. Werstuck ?árka Lhoták A.B. Lawrence de Koning Sudesh K. Sood Gazi S. Hossain Jan M?ller Merel Ritskes-Hoitinga Erling Falk Sanjana Dayal Steven R. Lentz Richard C. Austin | 2004 | Circulation: Journal of the American Heart Association2004，，2： | 1 |
| 8 | Routing to Manage Resolution and Waiting Time in Call Centers with Heterogeneous Servers 显示文摘 | Mehrotra Vijay Ross Kevin Ryder Geoff Zhou Yong Pin | 2012 | Manufacturing & Service Operations Management2012，14，1： | 1 |
| 9 | Hyperhomocysteinemia and its role in the development of atherosclerosis显示文摘 | A.B. Lawrence de Koning Geoff H. Werstuck Ji Zhou Richard C. Austin | 2003 | Clinical Biochemistry2003，，6： | 1 |
| 10 | A calorimetric investigation of thermodynamic and molecular mobility contributions to the physical stability of two pharmaceutical glasses显示文摘 | Zhou Deling Grant David J W Zhang Geoff G Z | 2007 | Pharm Sci2007，96，： | 1 |
| 11 | Partial carbon permits allocation of potential emission trading scheme in Australian electricity market显示文摘 | ZHOU Xun GEOFF J ARIEL L | | 0，，01： | 1 |
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