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| 1 | Performance of the Montreal classification for inflammatory bowel diseases显示文摘AIM:To validate the Montreal classification system for Crohn's disease(CD) and ulcerative colitis(UC) within the Netherlands.METHODS:A selection of 20 de-identified medical records with an appropriate representation of the inflammatory bowel disease(IBD) sub phenotypes were scored by 30 observers with different professions(gastroenterologist specialist in IBD,gastroenterologist in training and IBD-nurses) and experience level with IBD patient care.Patients were classified according to the Montreal classification.In addition,participants were asked to score extra-intestinal manifestations(EIM) and disease severity in CD based on their clinical judgment.The inter-observer agreement was calculated by percentages of correct answers(answers identical to the 'expert evaluation') and Fleiss-kappa(k).Kappa cutoffs:< 0.4-poor; 0.41-0.6-moderate; 0.61-0.8-good; > 0.8 excellent.RESULTS:The inter-observer agreement was excellent for diagnosis(k = 0.96),perianal disease(k = 0.92) and disease location in CD(k = 0.82) and good for age of onset(k = 0.67),upper gastrointestinal disease(k = 0.62),disease behaviour in CD(k = 0.79) and disease extent in UC(k = 0.65).Disease severity in UC was scored poor(k = 0.23).The additional items resulted in a good inter-observer agreement for EIM(k = 0.68) and a moderate agreement for disease severity in CD(k = 0.44).Percentages of correct answers over all Montreal items give a good reflection of the inter-observer agreement(> 80%),except for disease severity(48%-74%).IBD-nurses were significantly worse in scoring upper gastrointestinal disease in CD compared to gastroenterologists(P = 0.008) and gastroenterologists in training(P = 0.040).Observers with less than 10 years of experience were significantly better at scoring UC severity than observers with 10-20 years(P = 0.003) and more than 20 years(P = 0.003) of experience with IBD patient care.Observers with 10-20 years of experience with IBD patient care were significantly better at scoring upper gastrointestinal disease in CD than observers with less than 10 years(P = 0.007) and more than 20 years(P = 0.007) of experience with IBD patient care.CONCLUSION:We found a good to excellent interobserver agreement for all Montreal items except for disease severity in UC(poor). | Lieke M Spekhorst Marijn C Visschedijk Rudi Alberts Eleonora A Festen Egbert-Jan van der Wouden Gerard Dijkstra Rinse K Weersma | 2014 | World Journal of Gastroenterology2014，20，41： | 4 |
| 2 | Application of an electronic nose to correlate with descriptive sensory analysis of aged cheddar cheese显示文摘 | DRAKEA M A GERARD P D KLEINHENZ J P | 2003 | Lebensm Wiss U Technol2003，36，： | 1 |
| 3 | Alginate hydrogels as synthetic extraeellular matrix materials 显示文摘 | Jon A R Gerard M Mooney D J | 1999 | Biomaterials1999，20，： | 1 |
| 4 | 显示文摘 | Jon A R Gerard M | 1999 | Biomaterials1999，20，： | 1 |
| 5 | IR Seeker Simulator and IR Scene Generation to Evaluate IR Decoy Effectiveness显示文摘 | Wim de Jong Frans A M Dam Gerard J Kunz | 2004 | SPIE Technologies for Optical Countermeasures2004，5615，： | 1 |
| 6 | Six percent oxygen enrichment of room air at simulated 5000m altitude improves sneuropsychological function显示文摘 | Mcelroy M K Taylir M J | 2000 | High Alt Med Biol2000，1，1： | 1 |
| 7 | Staging laparoscopy with laparoscopic ultrasonography: optimizing resectability in hepatobiliary and pancreatic malignancy显示文摘 | Mark P Callery Steven M Strasberg Gerard M Doherty Nathaniel J Soper Jeffrey A Norton | 1997 | Journal of the American College of Surgeons1997，，1： | 1 |
| 8 | Nocturnal 02 onrichment of room air at high altitude increases daytime 02 Saturation without changing control of ventilation显示文摘 | Gerard A Powell F L | 2000 | High Alt Med Biol2000，1，3： | 1 |
| 9 | Sub-pixel image scaling for color-matrix displays 显示文摘 | Klompenhouwer M A de Gerard H | 2003 | Journal of the SID2003，11，1： | 1 |
| 10 | Upper echelons research revisited:antecedents,ele-ments,and consequences of top management team corn position显示文摘 | CARPENTER M A GELETKANYCZ M A GERARD S W | | 0，，06： | 1 |
| 11 | Influence of ozonation of humic and fulvic acids on diuron adsorption on activated carbon显示文摘 | Gerard M C Barthelemy J P Copin A | 2003 | Ozone-Science and Engineering2003，25，5： | 1 |
| 12 | Internationalization and firm governance: The roles of CEO compensation, top team composition, and board structure显示文摘 | W M Gerard Sanders and Mason A Carpenter | 1998 | The Academy of Management Journal1998，41，2： | 1 |
| 13 | The effects of key switch stiffness on typing force, finger electromyography, and subjective discomfort显示文摘 | Gerard M J Armstrong T J Franzblau A | 1999 | American Industrial Hygiene Association Journal1999，60，6： | 1 |
| 14 | Population bottleneck andeffective size in Bonamia ostreae-resistant populations of Ostrea edulis as inferred by microsatellite markers显示文摘 | Launey S Barrc M Gerard A | 2001 | Genet Res Camb2001，78，3： | 1 |
| 15 | Lysine 394 is a novel Rad6B-induced ubiquitination site on beta-catenin 显示文摘 | Gerard B Sanders M A Yisscher D W | 2012 | Biochim Biophys Acta2012，1823，10： | 1 |
| 16 | Determination of the Stoiehiometrie Composition of High-Temper-ature Superconductors by ICP-OES for Production Control显示文摘 | Geilenberg D Gerards M Broekaert J A C | | 0，，： | 1 |
| 17 | Relationship between instrumental and sensory measurements of cheese texture 显示文摘 | DRAKE M A GERARD P D TRUONG V D | 1999 | Journal of Texture Studies1999，30，4： | 1 |
| 18 | 1/N Expansion for Exclusive and Inclusive Charm Decays显示文摘 | Buras A J Gerard J M Ruckl R | 1986 | Nucl Phys1986，268，： | 1 |
| 19 | FoxO transcription factors blunt cardiac hypertrophy by inhibiting calcineurin signaling显示文摘 | Ni Y G Berenji K Wang N Oh M Sachan N Dey A Cheng J Lu G Morris D J Castrillon D H Gerard R D Rothermel B A Hill J A | | 0，，： | 1 |
| 20 | FoxO transcription factors activate Akt and attenuate insulin signaling in heart by inhibiting protein phosphatases显示文摘 | Ni Y G Wang N Cao D J Sachan N Morris D J Gerard R D Kuro-O M Rothermel B A Hill J A | | 0，，： | 1 |
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