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| 1 | Thermal cracking of aviation kerosene for scramjet applications显示文摘Thermal cracking of China No.3 aviation kerosene was studied experimentally and analytically under supercritical conditions relevant to regenerative cooling system for Mach-6 scramjet applications. A two-stage heated tube system with cracked products collection/analysis was used and it can achieve a fuel temperature range of 700―1100 K,a pressure range of 3.5―4.5 MPa and a residence time of ap-proximately 0.5―1.3 s. Compositions of the cracked gaseous products and mass flow rate of the kerosene flow at varied temperatures and pressures were obtained experimentally. A one-step lumped model was developed with the cracked mixtures grouped into three categories:unreacted kerosene,gaseous products and residuals including liquid products and carbon deposits. Based on the model,fuel conversion on the mass basis,the reaction rate and the residence time were estimated as functions of temperature. Meanwhile,a sonic nozzle was used for the control of the mass flow rate of the cracked kerosene,and correlation of the mass flow rate gives a good agreement with the measurements. | ZHONG FengQuan FAN XueJun YU Gong LI JianGuo | 2009 | Science China(Technological Sciences)2009，52，9： | 18 |
| 2 | Neural Networks Combined with Importance Sampling Techniques for Reliability Evaluation of Explosive Initiating Device显示文摘Concerning the issue of high-dimensions and low-failure probabilities including implicit and highly nonlinear limit state function, reliability analysis based on the directional importance sampling in combination with the radial basis function (RBF) neural network is used, and the RBF neural network based on first-order reliability method (FORM) is to approximate the unknown implicit limit state functions and calculate the most probable point (MPP) with iterative algorithm. For good efficiency, based on the ideas that directional sampling reduces dimensionality and importance sampling focuses on the domain contributing to failure probability, the joint probability density function of importance sampling is constructed, and the sampling center is moved to MPP to ensure that more random sample points draw belong to the failure domain and the simulation efficiency is improved. Then the numerical example of initiating explosive devices for rocket booster explosive bolts demonstrates the applicability, versatility and accuracy of the approach compared with other reliability simulation algorithm. | GONG Qi ZHANG Jianguo TAN Chunlin WANG Cancan | 2012 | Chinese Journal of Aeronautics2012，25，2： | 10 |
| 3 | Controlled WISP-1 shRNA Delivery Using Thermosensitive Biodegradable Hydrogel in the Treatment of Osteoarthritis显示文摘 | Gong Yubao Ma Hecheng Liu Jianguo | 2015 | Journal of Bionic Engineering2015，12，2： | 3 |
| 4 | Exome sequencing reveals genetic architecture in patients with isolated or syndromic short stature显示文摘Short stature is among the most common endocrinological disease phenotypes of childhood and may occur as an isolated finding or in conjunction with other clinical manifestations.Although the diagnostic utility of clinical genetic testing in short stature has been implicated,the genetic architecture and the utility of genomic studies such as exome sequencing(ES)in a sizable cohort of patients with short stature have not been investigated systematically.In this study,we recruited 561 individuals with short stature from two centers in China during a 4-year period.We performed ES for all patients and available parents.All patients were retrospectively divided into two groups:an isolated short stature group(group I,n=257)and an apparently syndromic short stature group(group II,n=304).Causal variants were identified in 135 of 561(24.1%)patients.In group I,29 of 257(11.3%)of the patients were solved by variants in 24 genes.In group II,106 of 304(34.9%)patients were solved by variants in 57 genes.Genes involved in fundamental cellularprocess played an important role in the genetic architecture of syndromic short stature.Distinct genetic architectures and pathophysiological processes underlie isolated and syndromic short stature. | Xin Fan Sen Zhao Chenxi Yu Di Wu Zihui Yan Lijun Fan Yanning Song Yi Wang Chuan Li Yue Ming Baoheng Gui Yuchen Niu Xiaoxin Li Xinzhuang Yang Shiyu Luo Qiang Zhang Xiuli Zhao Hui Pan Mei Li Weibo Xia Guixing Qiu Pengfei Liu Shuyang Zhang Jianguo Zhang Zhihong Wu James R.Lupski Jennifer E.Posey Shaoke Chen Chunxiu Gong Nan Wu | 2021 | Journal of Genetics and Genomics2021，48，5： | 2 |
| 5 | Serotonin in human skin显示文摘In this review the authors summarize data of a potential role for serotonin in human skin physiology and pathology. The uncovering of endogenous serotonin synthesis and its transformation to melatonin underlines a putative important role of this pathway in melanocyte physiology and pathology. Pathways of the biosynthesis and biodegradation of serotonin have been characterized in human beings and its major cellular populations. Moreover, receptors of serotonin are expressed on keratinocytes, melanocytes, and fibroblasts and these mediate phenotypic actions on cellular proliferation and differentiation. And the widespread expression of a cutaneous seorotoninergic system indicates considerable selectivity of action to facilitate intra-, auto-, or paracrine mechanisms that define and influence skin function in a highly compartmentalized manner. Melatonin, in turn, can also act as a hormone, neurotransmitter, cytokine, biological modifier and immunomodulator. Thus, Serotonin local synthesis and cellular localization could thus become of great importance in the diagnosis and management of cutaneous pathology. | Jianguo Huang Qiying Gong Guiming Li | 2005 | Journal of Nanjing Medical University2005，19，4： | 2 |
| 6 | All five COVID-19 outbreaks during epidemic period of 2020/2021 in China were instigated by asymptomatic or pre-symptomatic individuals显示文摘Introduction:The significance of asymptomatic or pre-asymptomatic individuals in driving the COVID-19 epidemic in China or other countries remains uncertain.Method:We collected and analyzed all the epidemiologic and virological diagnostic details of the infected individuals released by public health authorities and reiterated every episode of outbreak on a timeline.All individuals associated with the five outbreaks had tested positive for SARS-CoV-2 infection.Results:In this study,all five COVID-19 outbreaks reported in China since October 2020 were analyzed.The Kashgar outbreak in Xinjiang province came into light for the first time on October 22,2020.However,it was initiated before October 11,2020,by a local asymptomatic import and export worker,who was infected at the working place.Subsequently,his wife caught the infection,which led to 430 more infections reported in the outbreak.The Beijing outbreak with 41 cases was noticed for the first time on December 22,2020.However,our analysis revealed that it was initiated by an asymptomatic individual from Indonesia on December 10,2020.The Shenyang outbreak,with 38 cases,noticed for the first time on December 23,2020,was initiated by a pre-symptomatic individual from South Korea on December 13,2020.Conclusion:The asymptomatic or pre-symptomatic individuals during the asymptomatic period were unsuspectingly infected by SARS-CoV-2,and unintentionally transmitted the virus to a large number of people.These findings suggest that early detection of asymptomatic or pre-symptomatic individuals is of critical importance in preventing future outbreaks or epidemics. | Caixin Yang Sihui Zhang Shan Lu Jing Yang Yanpeng Cheng Yue Liu Lijun Zhao Jian Gong Jianguo Xu | 2021 | Journal of Biosafety and Biosecurity2021，3，1： | 1 |
| 7 | Investigation of Vaporized Kerosene Injection and Combustion in a Super- sonic Model Combustion 显示文摘 | Fan Xuejun Yu Gong Li Jianguo | 2006 | Journal of Propulsion and Power2006，22，1： | 1 |
| 8 | Action Categorization with Modified Hidden Conditional Random Field显示文摘 | Jianguo Zhang Shaogang Gong | 2010 | Pat- tern Recognition2010，43，： | 1 |
| 9 | EIS study of corrosion behaviour of organic coating/Dacromet composite systems显示文摘 | Liu Jianguo Gong Gaoping Yan Chuanwei | 2005 | Electrochimica Acta2005，50，1617： | 1 |
| 10 | One-step Synthesis of Cobalt-phthalovyanine/Iron Nanocomposite Partieles with High Magnetie Susceptibility显示文摘 | Gaun Jianguo Wang Wei Gong Rongzhou | 2002 | Langmuir2002，18，： | 1 |
| 11 | Enhancement of the Erosion-corrosion Resistance of Dcomet with Hybrid SiO2 Sol-gel显示文摘 | Liu Jianguo Gong Gaoping Yah Chuanwei | | 0，，： | 1 |
| 12 | Action categorization withmodified hidden conditional random field 显示文摘 | Zhang Jianguo Gong Shaogang | 2010 | Pattern Recog- nition2010，43，1： | 1 |
| 13 | Action categorization by structuralprobabilistic latent semantic analysis显示文摘 | Zhang Jianguo Gong Shaogang | 2010 | Computer Vision and Im-age Understanding2010，114，8： | 1 |
| 14 | Action categorization with modified hidden conditional random field显示文摘 | Jianguo Zhang Shaogang Gong | 2010 | Pattern Reconition2010，43，1： | 1 |
| 15 | Novel method for preparation of quaternary ammonium ionomer from epoxidized SBS and its use as compatibilizer显示文摘 | Xie Hongquan Chen Yong Gong Jianguo | 2006 | J Appl Polym Sci2006，99，4： | 1 |
| 16 | Action Gategorization with Modified Hidden Conditional Random Field显示文摘 | Zhang Jianguo Gong Shaogang | 2010 | Pattern rec- ognition2010，43，： | 1 |
| 17 | EIS study of corrosion behaviour of organic coating/Dacromet composite systems显示文摘 | Liu Jianguo Gong Gaoping Yan Chuanwei | 2004 | Electrochimica Acta2004，，16： | 1 |
| 18 | 显示文摘 | Guan Jianguo Wang Wei Gong Rongzhou | 2002 | Langmuir2002，18，11： | 1 |
| 19 | 查看详情显示文摘 | Lv Jianguo Gong Wanbing Huang Kai | | 0，，02： | 1 |
| 20 | Highly transparent conductive and near-infrared reflective ZnO:Al thin films显示文摘 | Li Gong Zhizhen Ye Jianguo Lu Liping Zhu Jingyun Huang Xiuquan Gu Binghui Zhao | 2010 | Vacuum2010，，7： | 1 |
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