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| 1 | Novel therapeutic agents in the treatment of metastatic colorectal cancer显示文摘Over the past couple of decades considerable progress has been made in the management of metastatic colorectal cancers(mCRC) leading to a significant improvement in five-year survival. Although part of this success has been rightly attributed to aggressive surgical management and advances in other adjunct treatments, our understanding of the pathogenesis of cancer and emergence of newer molecular targets for colon cancer has created a powerful impact. In this review article we will discuss various targeted therapies in the management of mCRC. Newer agents on the horizon soon to be incorporated in clinical practice will be briefly reviewed as well. | sachin gopalkrishna pai jyotsna fuloria | 2016 | World Journal of Gastrointestinal Oncology2016，8，1： | 2 |
| 2 | Amenability to dry processing of high ash thermal coal using a pneumatic table显示文摘High ash thermal coal from India was used to conduct the dry processing of fine coal using a pneumatic table to evolve a techno-economically novel technique. The fine as-received sample having 55.2% ash was subjected to washability studies at variant densities from 1.4 to 2.2 to assess the amenability to separation. The experiments were conducted using a central composite design for assessing the interactive effects of the variable parameters of a pneumatic table on the product yield and ash content. The performance of the pneumatic table was analyzed in terms of clean coal yield, recovery of combustibles,separation efficiency(E sp) and useful heat value of clean coal. The combustibles of clean coal obtained through a single stage operation at 35% and 38.7% ash were 40% and 63% respectively. However, the two stage processing was more effective in reducing the ash content in the clean coal. The rougher concentrate generated at higher ash level was subsequently processed in different conditions at 35% ash level, and 58% combustibles could be recovered. Hence, two stage processing increases the combustibles by 18 units and the useful heat value of clean coal increases from 1190 kcal/kg to 3750 kcal/kg. | Dey Shobhana Gangadhar B. Gopalkrishna S.J. | 2015 | International Journal of Mining Science and Technology2015，25，6： | 2 |
| 3 | A high frequency of human papillomavirus DNA sequences in cervical carcinomas of Indian women as revealed by Southern blot hybridization and polymerase chain reaction显示文摘 | Das BC Sharma JK Gopalkrishna V | 1992 | J Med Virol1992，36，： | 1 |
| 4 | Can bilateral bronchospasm be a sign of unilateral phrenic nerve palsy after supraclavicular brachial plexus block? 显示文摘 | Chaudhuri S Gopalkrishna M Paul C | 2012 | J Anaesthesiol Clin Pharmacol2012，28，2： | 1 |
| 5 | Detection of My coplasma species in cell culture by PCR and RFLP based method effect of BM cyclin to cure infections显示文摘 | Gopalkrishna V Verma H Kumbhar NS | 2007 | Indian J Med Microbiol2007，25，4： | 1 |
| 6 | Changing profile of prostatic abscess显示文摘 | Bhagut SK Kekre NS Gopalkrishna G | 2008 | Int Braz J Urol2008，34，： | 1 |
| 7 | Absence of human papillomavirus DNA in breast cancer as revealed by polymcrase chain reaction显示文摘 | Gopalkrishna V Singh UR Sodhani P | 1996 | Breast Cancer Res Treat1996，39，2： | 1 |
| 8 | Absence of human papillomavirus DNA in breast cancer as revealed by polymerase chain reaction显示文摘 | V. Gopalkrishna U. R. Singh P. Sodhani J. K. Sharma S. T. Hedau A. K. Mandal B. C. Das | 1996 | Breast Cancer Research and Treatment1996，，2： | 1 |
| 9 | Circulation of multiple enterovirus serotypes causing hand, foot and mouth disease in India 显示文摘 | Gopalkrishna V Patil PR Patil GP et 01 | 2012 | J Med Microbiol2012，61，3： | 1 |
| 10 | Circulation of multiple enterovirus serotypes causing hand,foot and mouth disease in India显示文摘 | Gopalkrishna V Patil PR Patil GP | 2012 | J Med Microbiol2012，61，3： | 1 |
| 11 | Biotypes and virulence factors Of Gardne-rella vaginalis isolated from cases of bacterialVaginosis 显示文摘 | Udayalaxrni J Gopalkrishna BK Kotigadde S | 2011 | India Journal of Medical Microbiology2011，29，2： | 1 |
| 12 | Circulation of multipleentemvirus semtypes causing hand, foot and mouth disease inlndia显示文摘 | Gopalkrishna V Patil P R Patil G P | 2012 | J Med Microbiol2012，61，3： | 1 |
| 13 | Circulation of multiple enterovirus serotypes causing hand,foot and mouth disease in India显示文摘 | Gopalkrishna V Patil P R Patil G P Chitambar S D | 2012 | J Med Microbiol2012，61，3： | 1 |
| 14 | Circulation of multiple enterovirus serotypes causing hand, foot and mouth disease in India 显示文摘 | Gopalkrishna V Patil Pr Patil G P | 2012 | J Med Microbiol2012，61，3： | 1 |
| 15 | Burden,Characteristics,and Outcome of Injury among Females:Observations from Bengaluru,India显示文摘 | Rajesh Kavita Nagarajarao Girish Gopalkrishna Gururaj | | 0，，04： | 1 |
| 16 | A high frequency of human papillomavirus DNA sequences in cervical carcinomas of Indian women as revealed by Southern blot hybridization and polymerase chain reaction显示文摘 | Das BC Sharma JK Gopalkrishna V | 1992 | J Med Virol1992，36，4： | 1 |
| 17 | A Frequency of human papillomavirus DNA sequences incervical carcinomas of Indian women as revealed by southern blot hybridization and polymerase chain reaction显示文摘 | Das BC Shanna JK Gopalkrishna V | 1992 | J Med Virol1992，36，4： | 1 |
| 18 | Can bilateral bronchospasm be a sign of unilateral phrenic nerve palsy after supraclavicular brachial plexus block 显示文摘 | Chaudhuri S Gopalkrishna M Paul C | 2012 | J Anaesthesiol Clin Pharmacol2012，28，2： | 1 |
| 19 | Circulation of multiple enterovirus serotypes causing hand,foot and mouth disease in India显示文摘 | GOPALKRISHNA V PATIL PR PATIL GP | 2012 | Journal of medical microbiology2012，61，3： | 1 |
| 20 | Circulation of multiple enterovirus serotypes causing hand,foot and mouth disease in India显示文摘 | Gopalkrishna V Patil P R Patil G P | 2012 | J Med Microbial2012，61，3： | 1 |
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