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| 1 | High quality reference genome of drumstick tree(Moringa oleifera Lam.), a potential perennial crop显示文摘The drumstick tree(Moringa oleifera Lam.) is a perennial crop that has gained popularity in certain developing countries for its high-nutrition content and adaptability to arid and semi-arid environments. Here we report a high-quality draft genome sequence of M. oleifera. This assembly represents 91.78% of the estimated genome size and contains 19,465 protein-coding genes. Comparative genomic analysis between M. oleifera and related woody plant genomes helps clarify the general evolution of this species, while the identification of several species-specific gene families and positively selected genes in M. oleifera may help identify genes related to M. oleifera's high protein content, fast-growth, heat and stress tolerance. This reference genome greatly extends the basic research on M. oleifera, and may further promote applying genomics to enhanced breeding and improvement of M. oleifera. | TIAN Yang ZENG Yan ZHANG Jing YANG Cheng Guang YAN Liang WANG XuanJun SHI ChongYing XIE Jing DAI TianYi PENG Lei ZENG HUAN Yu XU An Ni HUANG YeWei ZHANG JiaJin MA Xiao DONG Yang HAO ShuMei SHENG Jun | 2015 | Science China(Life Sciences)2015，58，7： | 10 |
| 2 | Activatingα7nAChR ameliorates abdominal aortic aneurysm through inhibiting pyroptosis mediated by NLRP3 inflammasome显示文摘Abdominal aortic aneurysm(AAA)is defined as a dilated aorta in diameter at least 1.5 times of a normal aorta.Our previous studies found that activatingα7 nicotinic acetylcholine receptor(α7nAChR)had a protective effect on vascular injury.This work was to investigate whether activatingα7nAChR could influence AAA formation and explore its mechanisms.AAA models were established by angiotensin II(Ang II)infusion in ApoE^(-/-)mice or in wild type andα7nAChR^(-/-)mice.In vitro mouse aortic smooth muscle(MOVAS)cells were treated with tumor necrosis factor-α(TNF-α).PNU-282987 was chosen to activateα7nAChR.We found that cell pyroptosis effector GSDMD and NLRP3 inflammasome were activated in abdominal aorta,and inflammatory cytokines in serum were elevated in AAA models of ApoE^(-/-)mice.Activatingα7nAChR reduced maximal aortic diameters,preserved elastin integrity and decreased inflammatory responses in ApoE^(-/-)mice with Ang II infusion.Whileα7nAChR^(-/-)mice led to aggravated aortic injury and increased inflammatory cytokines with Ang II infusion when compared with wild type.Moreover,activatingα7nAChR inhibited NLRP3/caspase-1/GSDMD pathway in AAA model of ApoE^(-/-)mice,whileα7nAChR deficiency promoted this pathway.In vitro,N-acetylcysteine(NAC)inhibited NLRP3 inflammasome activation and NLRP3 knockdown reduced GSDMD expression,in MOVAS cells treated with TNF-α.Furthermore,activatingα7nAChR inhibited oxidative stress,reduced NLRP3/GSDMD expression,and decreased cell pyroptosis in MOVAS cells with TNF-α.In conclusion,our study found that activatingα7nAChR retarded AAA through inhibiting pyroptosis mediated by NLRP3 inflammasome.These suggested thatα7nAChR would be a potential pharmacological target for AAA. | Hui Fu Qi-rui Shen Yi Zhao Min Ni Can-can Zhou Ji-kuai Chen Chen Chi Dong-jie Li Guang Liang Fu-ming Shen | 2022 | Acta Pharmacologica Sinica2022，43，10： | 3 |
| 3 | Norovirus Infection and Histo-blood Group Antigens in Children Hospitalized with Diarrhea in Lulong and Chenzhou in China显示文摘Norovirus(No V)is a pathogen that commonly causes viral diarrhea in children.Studies indicate that No V recognizes human histo-blood group antigens(HBGAs)as cell attachment factors.In order to explore the correlation between of No V infection and HBGAs,a cross-sectional study was conducted in children less than five years old who were hospitalized with diarrhea in two areas of China between November 2014 and February 2015. | SUN Xiao Man YAN Xiao Feng HE Zhi Gang Li Jing Xin GUO Ni Jun XU Zi Qian JIN Miao LI Dan Di ZHOU Yong Kang XIE Guang Cheng Pang Li Li ZHANG Qing LIU Na DUAN Zhao Jun | 2016 | Biomedical and Environmental Sciences2016，29，4： | 3 |
| 4 | Panda X-III: Searching for neutrinoless double beta decay with high pressure ^(136)Xe gas time projection chambers显示文摘Searching for the neutrinoless double beta decay(NLDBD)is now regarded as the topmost promising technique to explore the nature of neutrinos after the discovery of neutrino masses in oscillation experiments.Panda X-III(particle and astrophysical xenon experiment III)will search for the NLDBD of136Xe at the China Jin Ping Underground Laboratory(CJPL).In the first phase of the experiment,a high pressure gas Time Projection Chamber(TPC)will contain 200 kg,90%136Xe enriched gas operated at10 bar.Fine pitch micro-pattern gas detector(Microbulk Micromegas)will be used at both ends of the TPC for the charge readout with a cathode in the middle.Charge signals can be used to reconstruct the electron tracks of the NLDBD events and provide good energy and spatial resolution.The detector will be immersed in a large water tank to ensure~5 m of water shielding in all directions.The second phase,a ton-scale experiment,will consist of five TPCs in the same water tank,with improved energy resolution and better control over backgrounds. | Xun Chen Chang Bo Fu Javier Galan Karl Giboni Franco Giuliani Ling Hui Gu Ke Han Xiang Dong Ji Heng Lin Jiang Lai Liu Kai Xiang Ni Hiroki Kusano Xiang Xiang Ren Shao Bo Wang Yong Yang Dan Zhang Tao Zhang Li Zhao Xiang Ming Sun Shou Yang Hu Si Yu Jian Xing Long Li Xiao Mei Li Hao Liang Huan Qiao Zhang Ming Rui Zhao Jing Zhou Ya Jun Mao Hao Qiao Si Guang Wang Ying Yuan Meng Wang Amir N.Khan Neill Raper Jian Tang Wei Wang Jia Ning Dong Chang Qing Feng Cheng Li Jian Bei Liu Shu Bin Liu Xiao Lian Wang Dan Yang Zhu Juan F.Castel Susana Cebri'an Theopisti Dafni Javier G.Garza Igor G.Irastorza Francisco J.Iguaz Gloria Luz ′on Hector Mirallas Stephan Aune Eric Berthoumieux Yann Bedfer Denis Calvet Nicole d'Hose Alain Delbart Maria Diakaki Esther Ferrer-Ribas Andrea Ferrero Fabienne Kunne Damien Neyret Thomas Papaevangelou Franck Sabatie Maxence Vanderbroucke AnDi Tan Wick Haxton Yuan Mei Chinorat Kobdaj Yu-Peng Yan | 2017 | Science China(Physics,Mechanics & Astronomy)2017，60，6： | 2 |
| 5 | The application of automatic acquisition of knowledge to mix design of concrete显示文摘 | WANG JI - ZONG NI HONG - GUANG HE JIN - YUN | 1999 | Cement and Concrete Research1999，29，12： | 1 |
| 6 | Fabrication and Magnetic Properties of Co67Ni33 Alloy Nanowire Array显示文摘 | Hao Zhu Shaoguang Yang Guang Ni | 2001 | Scripta Mater2001，44，： | 1 |
| 7 | Poisson equation,poincare-lelong equation and decay on complete kahler manifold显示文摘 | Lei ni Yu guang shi Luen fai tam | 2001 | Differential Geometry2001，57，： | 1 |
| 8 | Transjugular intrahepatic portosystemic shunt induced short- and long-term cerebral blood flow variations in cirrhotic patients: an arterial spin labeling MRI study显示文摘 | Gang Zheng Long Jiang Zhang Yue Cao Zhiying Pan Rong Feng Qi Ling Ni Donghong Shi Xinxin Fan Guang Ming Lu | 2013 | Metabolic Brain Disease2013，，3： | 1 |
| 9 | Survival Benefit of Traditional Chinese Herbal Medicine (a Herbal Formula for Invigorating Spleen) for Patients With Advanced Gastric Cancer显示文摘 | Yan Xu Ai Guang Zhao Zhao Yan Li Gang Zhao Yong Cai Xiao Hong Zhu Ni Da Cao Jin Kun Yang Jian Zheng Yin Gu Ying Ying Han Ying Jie Zhu Jin Zu Yang Feng Gao Qiang Wang | 2013 | Integrative Cancer Therapies2013，，5： | 1 |
| 10 | Investigation on Technology of Automobile Vibration and Noise Reduction Based on Body-In-White Structure显示文摘 | Hu Qiao Sheng Ni Feng Zuo Shu Guang Lin Jian Ping Fang De Guang Guo Fu Xiang | 2011 | 2011 (474)2011，，474： | 1 |
| 11 | Enhancement effect of phase-conjugate waves of third order nonlinear medium in the Bragg microcavity显示文摘阶段结合波浪的改进效果由第三份订单生产了非线性的光媒介在一(AB ) N (D) 2 (BA ) 用一个维的 photonic 晶体做的 N 布拉格 microcavity 被学习。当回声条件被这个事件满足时,阶段结合波浪的获得因素被导出光波浪和布拉格 microcavity 模式。因为到布拉格 microcavity 给的事件泵横梁的更强壮的回声改进,阶段结合波浪的改进效果由在布拉格 microcavity 内的非线性的光媒介是比引起了由那突出的更多的第三份订单生产了裸体第三份订单非线性的光媒介。理论分析和数字计算证明当回声条件被这个事件满足时,有时期的更大的 numberN 的布拉格 microcavity 与一个 Fabry-Perot 洞是相同的光波浪和布拉格 microcavity 模式。CLC 数字 O734 文件代码 | JIANG Mei-ping CHEN Guang SHEN Xiao-ming GHEN Xian-feng NI Chong-wen SHI Du-fang | 2006 | Optoelectronics Letters2006，2，1： | 1 |
| 12 | Accumulation Pattern of Jurassic Tight Oil in Sichuan Basin and Its Exploration & Development Prospect显示文摘Jurassic tight oil in Sichuan Basin is chiefly distributed over the central basin with an area of about 4.2×104 km2.Since the first drilling in 1953,it has experienced four stages,including the Central Sichuan Basin Brought under Exploration and Development,Progressive Exploration and Development,Setting A Goal of 30×104 t/a,and Adjusting and Keeping A Stable Production.More than sixty-year exploration and development | LI Yaohua YANG Guang TAO Shizhen NI Chao CHEN Shijia LI Zhou | 2015 | Acta Geologica Sinica(English Edition)2015，89，A01： | 1 |
| 13 | Tetrahydrosalen backboned gadolinium complex as initiator for the ring-opening polymerization of ε-caprolactone显示文摘Tetrahydrosalen ligand was employed in the synthesis of gadolinium complex.The ligand was deprotoned by LiBu,and the afforded lithium salt was reacted with anhydrous GdCl_3 to produce the gadolinium complex through salt metathesis.This complex was successfully used to initiate the ring-opening polymerization ofε-caprolactone.The initiation conditions in different temperature,monomer-to-initiator ratio and time were investigated.Under the condition:[ε-caprolactone]:[catalyst]=600, 56℃,toluene:2 ml,poly(ε-caprolactone)(PCL)with Mw=11,2782 and PDI=1.96 was achieved. | Guang Ming Wu Xu Feng Ni Wei Lin Sun Zhi Quan Shen | 2008 | Chinese Chemical Letters2008，19，6： | 1 |
| 14 | Inhibition mechanism and model of an angiotensin I converting enzyme ( ACE ) -Inhibitory Hexapeptide fromYeast (Saccharomyces cerevisiae)显示文摘 | He Ni Lin Li Guang Liu | 2012 | Plos one2012，7，37： | 1 |
| 15 | Prevalence of human metapneumovirus in children with acute lower respiratory infection in Changsha, China显示文摘 | Ni‐guang Xiao Bing Zhang Zhi‐ping Xie Qiong‐hua Zhou Rong‐fang Zhang Li‐li Zhong Xiao‐fang Ding Jia Li Jing‐rong Song Han‐chun Gao Yun‐de Hou Zhao‐jun Duan | 2013 | J. Med. Virol2013，，： | 1 |
| 16 | Prevalence and risk factors of fatty liver disease in young and middle‐aged population: One center study in southwestern C hina显示文摘 | Shao‐Jun Xiao Guang‐Jian Fu Ya‐Lan Lv Xiao‐Ni Zhong Run‐Hua Wang | 2014 | J Gastroenterol Hepatol2014，，2： | 1 |
| 17 | A NEW CHEMICAL OSCILLATOR WITH A MACROCYCLIC COPPER(Ⅱ) COMPLEX AS THE CATALYST AND MALIC ACID AS THE SUBSTRATE显示文摘ANEWCHEMICALOSCILLATORWITHAMACROCYCLICCOPPER(Ⅱ)COMPLEXASACIDASTHESUBSTRATELiangZHAO;GuangLiHU;FuXinXIE;ZhiQiangXUandShiShengN... | Liang ZHAO Guang Li HU Fu Xin XIE Zhi Qiang XU and Shi Sheng NI(Department of Chemistry, Anhui University, Hefei 230039)(State Key Lab. of Coord. Chem., Nanjing Univ., Nanjing 210093) | 1996 | Chinese Chemical Letters1996，7，6： | 0 |
| 18 | NONTEMPLATE SYNTHESIS OF TWO N_2O_2S MACROCYCLES DERIVED FROM THIOPHENE,AND Hg(Ⅱ), Pb(Ⅱ), Cd(Ⅱ) COMPLEXES显示文摘NONTEMPLATESYNTHESISOFTWON_2O_2SMACROCYCLESDERIVEDFROMTHIOPHENE,ANDHg(Ⅱ),Pb(Ⅱ),Cd(Ⅱ)COMPLEXES￥LingZHAO;FuXinXIE;ZhiQiangXU;Gua... | Ling ZHAO Fu Xin XIE Zhi Qiang XU Guang YANG and Shi Sheng NI (Department of Chemistry,Anhui University ,Hefei 230039State Key Lab. of Coord. Chem., Nanjing University, Nanjing 210008) | 1994 | Chinese Chemical Letters1994，5，8： | 0 |
| 19 | SYNTHESIS AND CHARACTERIZATION OF A NEW THERMOTROPIC LIQUID CRYSTALLINE POLYESTER-ETHER SULFONE显示文摘A new aromatic thermotropic liquid crystalline polyester-ethersulfone(PEES)was prepared from 4,4-bis(4-hydroxyphenoxy)diphenylsulfone(BHPDS),terephthalic acid(TPA)and p-hydroxybenzoic acid(P-HBA).Somefactors that affected melting viscosity of polymer such as prepolymerizationreaction medium and post-polymerization etc,were discussed.The liquidcrystalline properties were characterized by DSC,polarizing microscope witha hot stage and WAXD measurements. | Yu Shan NI Yun Hui WANG Guang LI Xiao Ming JIN Meng Xian DING Changchun Institute of Applied Chemistry,Academia Sinica,Changchun 130022 | 1993 | Chinese Chemical Letters1993，4，2： | 0 |
| 20 | THE NON-TEMPLATE SYNTHESIS OF MACROCYCLIC SCHIFF BASE DERIVED FROM THIOPHENE,AND ITS Ag(Ⅰ),Hg(Ⅱ) COMPLEXES显示文摘THE NON-TEMPLATE SYNTHESIS OF MACROCYCLIC SCHIFF BASE DERIVED FROM THIOPHENE,AND ITS Ag(Ⅰ),Hg(Ⅱ) COMPLEXESTHENON-TEMPLATESYNT... | Liang ZHAO Fu Xin XIE Zhi Qiang XU Guang YANG and Shi Sheng NI(Department of Chemistry,Andui University,Hehi,230039)(National Key Lab. of Coord. Chem.in Nanjing University,Naming,210008) | 1994 | Chinese Chemical Letters1994，5，4： | 0 |
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