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| 1 | Mechanism and control of lake eutrophication显示文摘A review about lake naturally eutrophi- cating, the internal loading of nutrients from lake sediment as well as the mechanism of algal blooms and the control practices was made, especially the eutrophication problem of shallow lakes since sev- enty percent of fresh water lakes in China are shallow lakes. It was found that shallow lakes are apt toward eutrophication than deep lakes. Without any influ- ences of human activity, shallow lakes in the middle and lower reaches of Yangtze River are still easily eutrophicated, which may be owing to the effects of flood in this area. In shallow lakes, sediments are frequently disturbed by wind-wave and resuspended, which result in huge nutrients release to overlying water. This may be the major reason for higher in- ternal loading of nutrients in shallow lakes than in deep lakes. Algal bloom is an extreme response of lake ecosystem to the eutrophication. Appearance of algal blooms is related to physical condition of lakes, such as underwater radiation (or transparency), temperature, and hydrodynamic conditions, or related to geochemical conditions of lakes, like concentra- tions of nutrients and ratio of nitrogen to phosphorus, as well as the physiological advantage of cyanobac- teria such as vacuole for moving towards the radiant energy-rich zone and the mycosporine-like amino acids (MAAs) for resisting the harm of ultraviolet ra- diation. In shallow lakes, these advantages of cyanobacteria are favorable in the competition than in deep lakes. Also being the shallowness, it is more difficult to reduce nutrient loading and to control algae blooms in shallow lakes. For the control of eutrophi- cation, people should follow the sequence from pollution sources control, ecological restoration tocatchment management. To control the internal nu- trient release, physical, chemical, biological tech- niques, and even bionic techniques could be selected. The idea of ecological restoration for a eutrophic lake is to shift the ecosystem from phytoplankton-domi- nant state to macrophyte-dominant state. To realize the shift of ecosystem state, environmental condition improvement is the fundamental work. Nowadays, we should do more work on environmental condition improvement than on planting of macrophytes since we are lack of the knowledge about the relationship between macrophyte and lake ecosystem. Empha- sizing the macrophyte planting, therefore, has blind- ness at present. Because all lakes have different characteristics of environment and ecosystem, ap- plicable lake harness techniques should be selected based on the distinct ecosystem types and environ- mental problems. | QIN Boqiang YANG Liuyan CHEN Feizhou ZHU Guangwei ZHANG Lu CHEN Yiyu | 2006 | Chinese Science Bulletin2006,51,19: | 38 |
| 2 | The kinase AKT1 potentiates the suppressive functions of myeloid-derived suppressor cells in inflammation and cancer显示文摘Myeloid-derived suppressor cells(MDSCs)are a group of heterogeneous cells1 that play crucial negative regulatory roles in immune-associated diseases,including infections,2 cancer,3 transplantation4,and autoimmunity.5 We and others have shown that mTOR signaling and its downstream metabolic pathways regulate MDSC recruitment and function in inflammation and autoimmunity. | Anna Jia Yuexin Wang Yufei Wang Yan Li Qiuli Yang Yejin Cao Ying He Lin Dong Yingjie Dong Yueru Hou Ruoning Wang Yujing Bi Guangwei Liu | 2021 | Cellular & Molecular Immunology2021,18,4: | 7 |
| 3 | In-situ observations of internal dissolved heavy metal release in relation to sediment suspension in lake Taihu, China显示文摘Despite laboratory experiments that have been performed to study internal heavy metal release,our understanding of how heavy metals release in shallow eutrophic lakes remains limited for lacking in-situ evidence.This study used automatic environmental sensors and a water sampling system to conduct high-frequency in-situ observations(1-hr intervals)of water environmental variables and to collect water samples(3-hr intervals),with which to examine the release of internal heavy metals in Lake Taihu,China.Under conditions of disturbance by strong northerly winds,sediment resuspension in both the estuary area and the lake center caused particulate heavy metal resuspension.However,the patterns of concentrations of dissolved heavy metals in these two areas were complex.The concentrations of dissolved Se and Mo increased in both areas,indicating that release of internal dissolved Se and Mo is triggered by sediment resuspension.The concentrations of dissolved Ni,Zn,As,Mn,Cu,V,and Co tended to increase in the estuary area but decrease in the lake center.The different trends between these two areas were controlled by pH and cyanobacteria,which are related to eutrophication.During the strong northerly winds,the decrease in concentrations of dissolved heavy metals in the lake center was attributable primarily to absorption by the increased suspended solids,and to growth-related assimilation or surface adsorption by the increased cyanobacteria.The findings of this study suggest that,short-term changes of environmental conditions are very important in relation to reliable monitoring and risk assessment of heavy metals in shallow eutrophic lakes. | Tingfeng Wu Guangwei Zhu Jianghai Chen Tengteng Yang | 2020 | Journal of Environmental Sciences2020,32,11: | 7 |
| 4 | Artificial Selection in Domestication and Breeding Prevents Speciation in Rice显示文摘Speciation has long been regarded as an irreversible process once the reproductive barriers had been established.However,unlike in natural populations,artificial selection might either accelerate or prevent speciation processes in domesticated species.Asian cultivated rice is a target crop for both domestication and artificial breeding;it contains two subspecies of indica and japonica,which usually produce sterile inter-subspecific hybrids due to reproductive barriers.In this study,we constructed the evolutionary trajectory of a reproductive isolation system S5,which regulates fertility in indica-japonica hybrids via three adjacent genes,based on the data of 606 accessions including two cultivated and 11 wild rice species.Although hybrid sterility haplotypes at S5 lead to establishment of a killer-protector reproductive barrier,origin of wide-compatibility haplotypes by complex hybridization and recombination provides an opposing force to reproductive isolation and thus prevents speciation during domestication.Analysis in a diallel set of 209 crosses involving 21 parents showed that the wide-compatibility genotypes largely rescued fertility of indica-japonica hybrids,indicating that the wide-compatibility gene would enable gene flow to maintain species coherence.This counteracting system indicates that combined effects of natural evolution and artificial selection may result in reversible processes of speciation in rice,which may also have implications for genetic improvement of rice. | Jiaming Mi Guangwei Li Conghao Xu Jiangyi Yang Huihui Yu Gongwei Wang Xianghua Li Jinghua Xiao Huazhi Song Qifa Zhang Yidan Ouyang | 2020 | Molecular Plant2020,13,4: | 6 |
| 5 | IL-17A-dependent gut microbiota is essential for regulating diet-induced disorders in mice显示文摘The gut microbiota plays a key role in obesity and related metabolic disorders, and multiple factors including diet, host genotype, and age regulate it. Many studies have examined the contribution of extrinsic factors to the regulation of the gut microbiota, but the importance of the host genetic constitution cannot be ignored. Interleukin 17A(IL-17A), a pro-inflammatory cytokine, is important in the defense against infection and diseases. Here, we investigated the association among IL-17, a high-fat diet(HFD), and the gut microbiota. Mice deficient in IL-17A were resistant to diet-induced obesity and related diseases. Compared with the Ⅱ-17^(-/-)mice, wild-type(WT) mice challenged with HFD showed obvious weight fluctuations, such as those seen in type 2 diabetes, and hematological changes similar to those associated with metabolic syndrome. However, housing WT mice and Ⅱ-17a^(-/-)mice together significantly alleviated these symptoms in the WT mice. A metagenomic analysis of the mouse feces indicated that the microbial community compositions of these two groups differed before HFD feeding. The HFD mediated shifts in the gut microbial compositions, which were associated with the mouse phenotypes.We also identified potentially beneficial and harmful species present during this period, and drew networks of the most abundant species. A functional analysis indicated pathway changes in the WT and Ⅱ-17a^(-/-)mice when fed the HFD. Collectively, these data underscore the importance of the host factor IL-17 A in shaping and regulating the gut microbiota, which conversely, influences the host health. | Yujing Bi Chunxiao Li Lin Liu Jiyuan Zhou Zhengchao Li Huimin Deng Chunyan Wu Yanping Han Yajun Song Yafang Tan Xiaoyi Wang Zongmin Du Yujun Cui Yanfeng Yan Fachao Zhi Guangwei Liu Nan Qin Heping Zhang Ruifu Yang | 2017 | Science Bulletin2017,62,15: | 5 |
| 6 | Efficient Image Transmission Schemes over Zigbee-Based Image Sensor Networks显示文摘Image transmission is one of the biggest challenges in wireless sensor networks because of the limited resource on sensor nodes. We proposed two image transmission schemes driven by reliability and real time considerations in order to transfer JPEG images over Zigbee-based sensor networks. By adding two bytes counter in the header of data packet, we can easily solve the repeated data reception problem caused by retransmission mechanism in traditional Zigbees network layer. We proposed an efficient retransmission and acknowledgment mechanism in Zigbees application layer. By classifying different data reception response events, we can provide data packets with differential responses and ensure that image packets can be transferred quickly even with large maximum number of retransmission. Practical results show the effectiveness of our solutions to make image transmission over Zigbee-based sensor networks efficient. | TAO Dan YANG Guangwei CHEN Houjin WU Hao LIU Pingping | 2016 | Chinese Journal of Electronics2016,25,2: | 5 |
| 7 | Glucocorticoid receptor promotes the function of myeloid-derived suppressor cells by suppressing HIF1α-dependent glycolysis显示文摘Immunomodulatory signaling imposes tight regulations on metabolic programs within immune cells and consequentially determines immune response outcomes.Although the glucocorticoid receptor(GR)has been recently implicated in regulating the function of myeloid-derived suppressor cells(MDSCs),whether the dysregulation of GR in MDSCs is involved in immune-mediated hepatic diseases and how GR regulates the function of MDSCs in such a context remains unknown.Here,we revealed the dysregulation of GR expression in MDSCs during innate immunological hepatic injury(IMH)and found that GR regulates the function of MDSCs through modulating HIF1α-dependent glycolysis.Pharmacological modulation of GR by its agonist(dexamethasone,Dex)protects IMH mice against inflammatory injury.Mechanistically,GR signaling suppresses HIF1αand HIF1α-dependent glycolysis in MDSCs and thus promotes the immune suppressive activity of MDSCs.Our studies reveal a role of GR-HIF1αin regulating the metabolism and function of MDSCs and further implicate MDSC GR signaling as a potential therapeutic target in hepatic diseases that are driven by innate immune cell-mediated systemic inflammation. | Yun Lu Huanrong Liu Yujing Bi Hui Yang Yan Li Jian Wang Zhengguo Zhang Yu Wang Chunxiao Li Anna Jia Linian Han Ying Hu Yong Zhao Ruoning Wang Guangwei Liu | 2018 | Cellular & Molecular Immunology2018,15,6: | 4 |
| 8 | Decaying evolution dynamics of double-pulse mode-locking显示文摘Taking advantage of the dispersive Fourier transformation technique, the decaying evolution processes of doublepulse mode-locking in a single-walled carbon-nanotube-based Er-doped fiber laser are observed in detail for the first time to our knowledge. The decaying dynamics of the double-pulse mode-locking state is analyzed in the spectral and temporal domains. We reveal that the two pulses in one cluster disappear either simultaneously or one by one during the decaying processes of double-pulse mode-locking states. In addition, the spectral evolution patterns of the special double-pulse states(i.e., bound states) are extremely distinct at different decline rates of the pump power. | GUOMEI WANG GUANGWEI CHEN WENLEI LI CHAO ZENG HUIRAN YANG | 2018 | Photonics Research2018,6,8: | 4 |
| 9 | Regorafenib-loaded poly(lactide-co-glycolide) microspheres designed to improve transarterial chemoembolization therapy for hepatocellular carcinoma显示文摘Transarterial chemoembolization(TACE)has been widely introduced to treat hepatocellular carcinoma(HCC)especially for unresectable patients for decades.However,TACE evokes an angiogenic response due to the secretion of vascular endothelial growth factor(VEGF),resulting in the formation of new blood vessels and eventually tumor recurrence.Thus,we aimed to develop regorafenib(REGO)-loaded poly(lactide-co-glycolide)(PLGA)microspheres that enabled localized and sustained drug delivery to limit proangiogenic responses following TACE in HCC treatment.REGO-loaded PLGA microspheres were prepared using the emulsion-solvent evaporation/extraction method,in which DMF was selected as an organic phase co-solvent.Accordingly,we optimized the proportion of DMF,which the optimal ratio to DCM was 1:9(v/v).After preparation,the microspheres provided high drug loading capacity of 28.6%,high loading efficiency of 91.5%,and the average particle size of 149μm for TACE.IR spectra and XRD were applied to confirming sufficient REGO entrapment.The in vitro release profiles demonstrated sustained drug release of microspheres for more than 30 d To confirm the role of REGO-loaded microspheres in TACE,the cell cytotoxic activity on HepG2 cells and anti-angiogenic effects in HUVECs Tube-formation assay were studied in combination with miriplatin.Moreover,the microspheres indicated the potential of antagonizing miriplatin resistance of HepG2 cells in vitro.Pharmacokinetics preliminary studies exhibited that REGO could be sustainably released from microspheres for more than 30d after TACE in vivo.In vivo anti-tumor efficacy was further determined in HepG2 xenograft tumor mouse model,demonstrating that REGO microspheres could improve the antitumor efficacy of miriplatin remarkably compared with miriplatin monotherapy.In conclusion,the obtained REGO microspheres demonstrated promising therapeutic effects against HCC when combined with TACE. | Xiang Li Guangwei He Feng Su Zhaoxing Chu Leiming Xu Yazhong Zhang Jianping Zhou Yang Ding | 2020 | Asian Journal of Pharmaceutical Sciences2020,15,6: | 4 |
| 10 | Phyllotaxis-inspired nanosieves with multiplexed orbital angular momentum显示文摘Nanophotonic platforms such as metasurfaces,achieving arbitrary phase profiles within ultrathin thickness,emerge as miniaturized,ultracompact and kaleidoscopic optical vortex generators.However,it is often required to segment or interleave independent sub-array metasurfaces to multiplex optical vortices in a single nano-device,which in turn affects the device’s compactness and channel capacity.Here,inspired by phyllotaxis patterns in pine cones and sunflowers,we theoretically prove and experimentally report that multiple optical vortices can be produced in a single compact phyllotaxis nanosieve,both in free space and on a chip,where one meta-atom may contribute to many vortices simultaneously.The time-resolved dynamics of on-chip interference wavefronts between multiple plasmonic vortices was revealed by ultrafast time-resolved photoemission electron microscopy.Our nature-inspired optical vortex generator would facilitate various vortex-related optical applications,including structured wavefront shaping,free-space and plasmonic vortices,and high-capacity information metaphotonics. | Zhongwei Jin David Janoschka Junhong Deng Lin Ge Pascal Dreher Bettina Frank Guangwei Hu Jincheng Ni Yuanjie Yang Jing Li Changyuan Yu Dangyuan Lei Guixin Li Shumin Xiao Shengtao Mei Harald Giessen Frank Meyer zu Heringdorf Cheng-Wei Qiu | 2021 | eLight2021,1,1: | 3 |
| 11 | Persistence of Cry1Ac Protein from Transgenic Bt Cotton Cultivation and Residue Returning in Fields and Its Effect on Functional Diversity of Soil Microbial Communities显示文摘The persistence of Cry1 Ac protein in the soil and its effect on soil microbial communities are a core issue in assessing the ecological risk of transgenic Bacillus thuringiensis(Bt) cotton. In this study a field experiment was conducted on the cultivation of transgenic Bt cotton(Jin 26 and BtJ i 668) with the immediate returning of residues to the fields, in order to quantify the Cry1 Ac protein content in the fields and investigate its effects on the functional diversity of soil microbial communities. Cry1 Ac protein in the residue-soil mixture was gradually degraded in the transgenic Bt cotton fields. After transgenic Bt cotton straw was returned to the fields for 30 d, 63.73%and 58.33% of the initial amounts of Cry1 Ac protein were degraded in the Jin 26 and BtJ i 668 fields, respectively. Before the crops were sown in the following year(180 d after returning the straw), no Cry1 Ac protein was detected in the fields. After returning the cotton straw to the fields for 30 d, the Shannon-Wiener and McIntosh indices of soil microbial communities in the transgenic Bt cotton fields were significantly higher than those in the non-transgenic cotton fields. Meanwhile, the utilization of carbon sources including amino acids, amines, and carbohydrates by the soil microbial communities significantly increased. Both the McIntosh index and the utilization of carbohydrates increased until 180 d. Principal component analysis revealed that amino acids, amides, and carbohydrates were the main carbon sources distinguishing the two principal component factors. These findings indicated that Cry1 Ac protein did not accumulate in the fields after transgenic Bt cotton was planted for one year and the residues were immediately returned to the fields; however, the original functional diversity of soil microbial communities was affected continuously. | ZHANG Meijun FENG Meichen XIAO Lujie SONG Xiaoyan Guangwei DING YANG Wude | 2019 | Pedosphere2019,29,1: | 2 |
| 12 | Moderate sewage sludge biochar application on alkaline soil for corn growth:a field study显示文摘In view of the risks induced by the inhibitory effects of applying impracticably large amounts of sewage sludge biochar(SSB)to the alkaline soil,this field study investigated the influence of moderate biochar amendments(0,1500,4500,and 9000 kg/hm2)on corn growth,alkaline soil properties,and the uptake of potentially toxic elements(PTEs).The results showed that applying more SSB would decrease the ammonium nitrogen concentration and increase the available phosphorus and potassium concentrations,which inhibited corn plant growth because of high background nutrient levels of the alkaline soil.When the alkaline soil was amended with 1500 kg/hm2 SSB,the dry weight of 100 niblets increased from 32.11 g in the control to 35.07 g.There was no significant variation in the total concentration of PTEs in the soil.The concentrations of Mn,Ni,Cu,and Zn in niblets decreased from 5.54,0.83,2.26,and 27.15 mg/kg in the control to 4.47,0.62,1.30,and 23.45 mg/kg,respectively.Accordingly,the health risk from corn consumption was significantly reduced.Furthermore,the combination of SSB and fertilizer improved corn growth and reduced the risk of consumption of PTEs.Therefore,considering the increase in corn fruit yield and the decrease in consumption risk,applying 1500 kg/hm2 of biochar to alkaline soils is a realistically achievable rate,which can broaden the utilization of SSB for remediation of different types of soil. | Shengyu Xie Guangwei Yu Ruqing Jiang Jianli Ma Xiaofu Shang Gang Wang Yin Wang Yongan Yang Chunxing Li | 2021 | Biochar2021,3,2: | 2 |
| 13 | Network level pavement evaluation with 1 mm 3D survey system显示文摘The latest iteration of Pave Vision3D Ultra can obtain true 1 mm resolution 3D data at fulllane coverage in all 3 directions at highway speed up to 60 mph.This paper introduces the Pave Vision3D Ultra technology for rapid network level pavement survey on approximately1280 center miles of Oklahoma interstate highways.With sophisticated automated distress analyzer(ADA)software interface,the collected 1 mm 3D data provide Oklahoma Department of Transportation(ODOT)with comprehensive solutions for automated evaluation of pavement surface including longitudinal profile for roughness,transverse profile for rutting,predicted hydroplaning speed for safety analysis,and cracking and various surface defects for distresses.The pruned exact linear time(PELT)method,an optimal partitioning algorithm,is implemented to identify change points and dynamically determine homogeneous segments so as to assist ODOT effectively using the available 1 mm 3D pavement surface condition data for decision-making.The application of 1 mm 3D laser imaging technology for network survey is unprecedented.This innovative technology allows highway agencies to access its options in using the 1 mm 3D system for its design and management purposes,particularly to meet the data needs for pavement management system(PMS),pavement ME design and highway performance monitoring system(HPMS). | Kelvin C.P.Wang Qiang Joshua Li Guangwei Yang You Zhan Yanjun Qiu | 2015 | Journal of Traffic and Transportation Engineering(English Edition)2015,2,6: | 2 |
| 14 | SCFP, a novel fiber-specific promoter in cotton显示文摘To investigate the expression pattern of GhSCFP which was isolated from cotton fiber cDNA library, a 1006 bp upstream fragment of the gene was cloned by chromosome walking and fused to GUS and GFP respectively. Histochemical GUS and GFP fluorescence analysis revealed that the expression of the report genes driven by the promoter sequence was detectable only in outer layer cells during the seed development in the transgentic tobaccos. In transgenic cotton, strong GUS activity was observed in spherical protrusions on 0 dpa (days post anthesis) ovule surface, and in the 2―36 dpa fiber cells, while no GUS signals were detected in the root, leaves, stem, corolla, anther and stigma. Our data demonstrated that GhSCFP upstream sequence is a cotton fiber-specific promoter and this promoter will be useful in the molecular research on fiber cell development and in cotton fiber improvements by genetic modification. | HOU Lei LIU Hao LI JiaBao YANG Xia XIAO YueHua LUO Ming SONG ShuiQing YANG GuangWei PEI Yan | 2008 | Chinese Science Bulletin2008,53,17: | 2 |
| 15 | A New Key Exchange Protocol for Threer parties显示文摘 | Yang Xiumei Zhou Fucai Liu Guangwei Chang Guiran | 2009 | Joumal o f Northeastern University( Natural Science)2009,30,7: | 1 |
| 16 | Hysteroscopic surgery of ectopic pregnancy in the cesarean section scar显示文摘 | YANG Qing PIAO Shuhua WANG Guangwei | 2009 | Journal of Minimally Invasive Gynecology2009,16,4: | 1 |
| 17 | A novel sparse repre- sentation based framework for face image super- resolution 显示文摘 | Guangwei Gao Jian Yang | 2014 | Neurocomputing2014,134,25: | 1 |
| 18 | The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing Diabetes Prevention Study: a 20-year follow-up study显示文摘 | Guangwei Li Ping Zhang Jinping Wang Edward W Gregg Wenying Yang Qiuhong Gong Hui Li Hongliang Li Yayun Jiang Yali An Ying Shuai Bo Zhang Jingling Zhang Theodore J Thompson Robert B Gerzoff Gojka Roglic Yinghua Hu Peter H Bennett | 2008 | 2008 (9626)2008,,9626: | 1 |
| 19 | Transient Inclusion Evolution during RH Degassing显示文摘 | Guangwei Yang Xinhua Wang Fuxiang Huang Wanjun Wang Yuqun Yin | 2014 | steel research int2014,,1: | 1 |
| 20 | Evaluation of the Efficacy of Laparoscopic Resection for the Management of Exogenous Cesarean Scar Pregnancy显示文摘 | guangwei Wang xiaofei Liu fangfang Bi lili Yin rina Sa dandan Wang qing Yang | 2014 | Fertility and Sterility2014,,: | 1 |