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| 1 | Correlation of Gut Microbiome Between ASD Children and Mothers and Potential Biomarkers for Risk Assessment显示文摘Variation of maternal gut microbiota may increase the risk of autism spectrum disorders(ASDs) in offspring. Animal studies have indicated that maternal gut microbiota is related to neurodevelopmental abnormalities in mouse offspring, while it is unclear whether there is a correlation between gut microbiota of ASD children and their mothers. We examined the relationships between gut microbiome profiles of ASD children and those of their mothers, and evaluated the clinical discriminatory power of discovered bacterial biomarkers. Gut microbiome was profiled and evaluated by 16S ribosomal RNA gene sequencing in stool samples of 59 mother–child pairs of ASD children and 30 matched mother–child pairs of healthy children. Significant differences were observed in the gut microbiome composition between ASD and healthy children in our Chinese cohort. Several unique bacterial biomarkers, such as Alcaligenaceae and Acinetobacter, were identified. Mothers of ASD children had more Proteobacteria, Alphaproteobacteria, Moraxellaceae, and Acinetobacter than mothers of healthy children. There was a clear correlation between gut microbiome profiles of children and their mothers; however, children with ASD still had unique bacterial biomarkers, such as Alcaligenaceae, Enterobacteriaceae, and Clostridium. Candidate biomarkers discovered in this study had remarkable discriminatory power. The identified patterns of mother–child gut microbiome profiles may be important for assessing risks during the early stage and planning of personalized treatment and prevention of ASD via microbiota modulation. | Ning Li Junjie Yang Jiaming Zhang Cheng Liang Ying Wang Bin Chen Changying Zhao Jingwen Wang Guangye Zhang Dongmei Zhao Yi Liu Lehai Zhang Jun Yang Guimei Li Zhongtao Gai Lei Zhang Guoping Zhao | 2019 | Genomics, Proteomics & Bioinformatics2019，17，1： | 6 |
| 2 | Reducing energy loss via tuning energy levels of polymer acceptors for efficient all-polymer solar cells显示文摘The open-circuit voltage(Voc) of all-polymer solar cells(all-PSCs) is typically lower than 0.9 V even for the most efficient ones.Large energy loss is the main reason for limiting Voc and efficiency of all-PSCs. Herein, through materials design using electron deficient building blocks based on bithiophene imides, the lowest unoccupied molecular orbital(LUMO) energy levels of polymer acceptors can be effectively tuned, which resulted in a reduced energy loss induced by charge generation and recombination loss due to the suppressed charge-transfer(CT) state absorption. Despite a negligible driving force, all-PSC based on the polymer donor and acceptor combination with well-aligned energy levels exhibited efficient charge transfer and achieved an external quantum efficiency over 70% while maintaining a large Voc of 1.02 V, leading to a 9.21% efficiency. Through various spectroscopy approaches, this work sheds light on the mechanism of energy loss in all-PSCs, which paves an avenue to achieving efficient all-PSCs with large Voc and drives the further development of all-PSCs. | Huiliang Sun Bin Liu Jianwei Yu Xianshao Zou Guangye Zhang Yujie Zhang Wei Zhang Mengyao Su Qunping Fan Kun Yang Jianhua Chen He Yan Feng Gao Xugang Guo | 2020 | Science China Chemistry2020，63，12： | 2 |
| 3 | Long-term fertilization effects on grain yield, water-use efficiency and soil fertility in the dryland of Loess Plateau in China显示文摘 | Tinglu Fan B.A. Stewart Wang Yong Luo Junjie Zhou Guangye | 2004 | Agriculture, Ecosystems and Environment2004，，4： | 2 |
| 4 | Activation pretreatment of limonitic laterite ores by alkali-roasting method using sodium carbonate显示文摘 | Qiang Guo Jingkui Qu Tao Qi Guangye Wei Bingbing Han | 2011 | Minerals Engineering2011，，8： | 1 |
| 5 | Pricing policies in a dual-channel supply chain with retail services 显示文摘 | Dan Bin Xu Guangye Liu Can | 2012 | International Journal of Pro- duction Economics2012，139，： | 1 |
| 6 | Trends in grain yields and soil organic earbon in a long-term fertilization experiment in the China loess plateau American-Eurasian 显示文摘 | Tinglu F Minggang X Guangye Z | 2007 | Journal of Agriculture and Environ Science2007，2，： | 1 |
| 7 | Optimal extent of fluorination enabling strong temperature-dependent aggregation, favorable blend morphology and high-efficiency polymer solar cells显示文摘Temperature-dependent aggregation is a key property for some donor polymers to realize favorable bulk-heterojunction(BHJ)morphologies and high-efficiency(>10%) polymer solar cells.Previous studies find that an important structural feature that enables such temperature-dependent aggregation property is the 2nd position branched alkyl chains sitting between two thiophene units.In this report,we demonstrate that an optimal extent of fluorination on the polymer backbone is a second essential structural feature that enables the strong temperature-dependent aggregation property.We compare the properties of three structurally similar polymers with 0,2 or 4 fluorine substitutions in each repeating unit through an in-depth morphological study.We show that the non-fluorinated polymer does not aggregate in solution(0.02 mg mL^(-1) in chlorobenzene) at room temperature,which results in poor polymer crystallinity and extremely large polymer domains.On the other hand,the polymer with four fluorine atoms in each repeating unit exhibits an excessively strong tendency to aggregate,which makes it difficult to process and causes a large domain.Only the polymer with two fluorine atoms in each repeating unit exhibits a suitable extent of temperature-dependent aggregation property.As a result,its blend film achieves a favorable morphology and high power conversion efficiency.This provides another key design rationale for developing donor polymers with suitable temperature-dependent aggregation properties and thus high performance. | Guofang Yang Zhengke Li Kui Jiang Jie Zhang Jianya Chen Guangye Zhang Fei Huang Wei Ma He Yan | 2017 | Science China Chemistry2017，60，4： | 1 |
| 8 | Three phase to four phase transformer for four phase power transmission system显示文摘 | Liu Guangye Yang Yihan | 2002 | IEEE Transaction on Power Delivery2002，17，4： | 1 |
| 9 | Effect of gradient thermal distribution on butt joining of magnesium alloy to steel with Cu–Zn alloy interlayer by hybrid laser–tungsten inert gas welding显示文摘 | Gang Song Guangye An Liming Liu | 2011 | Materials and Design2011，，： | 1 |
| 10 | Effect of gradient thermal distribution on butt joining of magnesium alloy to steel with Cu-Zn alloy interlayer by hybrid laser-tungsten inert gas welding显示文摘 | Song Gang An Guangye Liu Liming | 2012 | Ma- terials and Design2012，35，： | 1 |
| 11 | Coordinating adual-channel supply chain with risk-averse under a two-way revenuesharing contract 显示文摘 | Xu Guangye Dan Bin Zhang Xumei | 2014 | International Journal of Production Economics2014，，147： | 1 |
| 12 | Coordinating a dual-channel supply chain with risk-ave~e under a two- way revenue sharing contract 显示文摘 | XU Guangye DAN Bin ZHANG Xumei | 2014 | International Journal of Production Economics2014，，1： | 1 |
| 13 | Pricing policies in a dual- channel supply chain with retail services显示文摘 | Dan Bin Xu Guangye Liu Can | 2012 | International Journal of Production Economics2012，139，1： | 1 |
| 14 | Elucidating the Molecular Mechanism of Dynamic Photodamage of Photosystem II Membrane Protein Complex by Integrated Proteomics Strategy显示文摘Photosystem II(PSII),as a multiple-subunit chloroplast membrane-associated pigment-protein complex on the thylakoid membrane,is a primary target of light-induced photodamage.However,the overall molecular details of the conformation and composition dynamics of PSII photodamage are still controversial.In this study,we investigated systematically the dynamic conformation,degradation,and oxidation processes of PSII photodamage by integrating chemical cross-linking and top-down proteomics strategies. | Ye Zhou Zheyi Liu Mingdong Yao Jun Chen Yanan Xiao Guangye Han Jian-Ren Shen Fangjun Wang | 2022 | CCS Chemistry2022，4，1： | 1 |
| 15 | Fabrication of hollow zeolite spheres using oil/water emulsions as templates显示文摘 | Xia Lixin Liu Guangye Liu Jingfu | 2011 | Inor ganic Chemistry Communications2011，14，8： | 1 |
| 16 | Pricing Policies in a Dual-channel Supply Chain with Retail Services 显示文摘 | Bin Dan Guangye Xu Can Liu | 2012 | International Journal ofProduction Economics2012，，139： | 1 |
| 17 | Three-phase to four-phase transformer for four-phase power transmission systems显示文摘 | Yang Yihan | 2002 | IEEE Trans on Power Delivery2002，17，4： | 1 |
| 18 | Pricing policies in a dual- channel supply chain with retail services显示文摘 | Dan Bin Xu Guangye Liu Can | 2012 | International Journal of Production Economics2012，，： | 1 |
| 19 | Cascade Compression Induced by Nonlinear Barriers in Propagation of Optical Solitons显示文摘 | Guangye Yang Ruiyu Hao Lu Li | 2006 | Opt Commun2006，260，： | 1 |
| 20 | Pricing policies in a dual-channel supply chain with retail services 显示文摘 | Bin Dan Guangye Xu Can Liu | 2012 | International Journal of Production Economics2012，139，： | 1 |
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