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| 1 | 米索前列醇和PG05配伍米非司酮终止早孕的临床多中心随机比较试验显示文摘本研究为一项由十个单位参加的多中心临床试验,随机比较了三种用药方案:1.米非司酮25mgQ12h×5+PG051mg阴道塞药(组Ⅰ),2.米非司酮,同前十米索600μg(组Ⅱ),3.米非司酮200mg+米索600μg(组Ⅲ)终止早孕的安全性、有效性和可接受性。结果显示完全流产率为94.22%(913/969),其中组Ⅲ为91.50%,明显低于组Ⅰ(95.22%)和组Ⅰ(96.12%)(P=0.025);失败率为1.65%(16/969),其中组Ⅲ为3.52%,显著高于组Ⅰ(1.37%)、组Ⅱ(0%)(P=0.001);不完全流产率为2.89%(28/969),失访(结局不明)率为1.24%(12/969),三组间均无明显差异(P>0.05);自应用PG至孕囊排出时间,三组分别为3.06±1.65,2.81±2.75,3.21±1.61h(X±SD),组Ⅱ稍短于其他两组,其差异有统计学意义(P<0.05);阴道出血持续时间和转经时间无明显组间差异(P>0.05)。90%以上的对象均对药物流产方法表示满意。结果提示米索配伍米非司酮的安全性、有效性和可接受性令人满意;米非司酮低剂量多次给药与米索有较好的协同作用。 | He Chang-hai Gao Er-sheng Chen Jun-hang Gu Jiang Gui You-lnn and Cao Feng-zhen et al.(Collabrating Grou) for Clinical Study on Misoprostol to induce Abortion, Shanghai, 200032) | 1994 | 生殖与避孕1994，14，1： | 47 |
| 2 | Process mineralogy of copper-nickel sulphide flotation by a cyclonic-static micro-bubble flotation column显示文摘In our study we investigated a refractory copper-nickel sulfide ore separation by using a cyclonic-static micro-bubble flotation column (FCSMC). The process mineralogy of the main products was studied. Using a scanning electron microscope-energy dispersive system (SEM-EDS) and an X-ray spectrometer the mineral category and content of samples were analyzed. By using a mineral liberation analyzer (MLA) the mineral liberation characteristics were revealed. It is shown that in roughing feed the monomers liberation degree of nickel pyrite and chalcopyrite take up 84.11% and 88.82%, respectively. In tailings, the lost nickel pyrite and chalcopyrite are mainly monomers. Therefore, strengthening the micro-fine particle recovery capacity is the key to increase recovery. | CAO Yi-jun GUI Xia-hui MA Zi-long YU Xiao-xia CHEN Xiao-dong ZHANG Xiu-pin | 2009 | Mining Science and Technology2009，19，6： | 25 |
| 3 | Hydraulic design and pre-whirl regulation law of inlet guide vane for centrifugal pump显示文摘A new hydraulic design method of three-dimensional guide vane for centrifugal pump is proposed on the assumption that the fluid at the outlet of guide vane satisfies the uniform velocity moment condition.The geometry of blade is controlled by the distributed rule of blade angles along the meridional streamline which is described by a fourth-order polynomial.Experiment results demonstrate that the designed guide vane can overcome the drawback of two-dimensional guide vane,enlarge the high efficiency scope and improve the hydraulic performance of centrifugal pump on the off-design operation conditions.In comparison with the performance of the centrifugal pump without inlet guide vane,the peak value of efficiency can be enhanced by 2.13% after the three-dimensional guide vane was being installed.The three-dimensional entire flow field of the centrifugal pump with inlet guide vane is simulated,and the basic principle and mechanism of inlet guide vane pre-whirl regulation are analyzed.The validity of design method has been proved. | TAN Lei ,CAO ShuLiang&GUI ShaoBo State Key Laboratory of Hydroscience and Engineering,Department of Thermal Engineering,Tsinghua University,Beijing 100084,China | 2010 | Science China(Technological Sciences)2010，53，8： | 14 |
| 4 | Identification of a Newly Isolated Getah Virus in the China-Laos Border,China显示文摘In this study, we isolated a virus strain(YN12031) from specimens of Armigeres subalbatus collected in the China-Laos border. BHK-21 cells infected with YN12031 exhibited an evident cytopathic effect(CPE) 32 h post-infection. The virus particles were spherical, 70 nm in diameter, and enveloped; they also featured surface fibers. Molecular genetic analysis revealed that YN12031 was closely related to alpha viruses such as Chikungunya virus and Sindbis virus, and located in the same clade as MM2021, the prototype of Getahvirus(GETV) isolated in Malaysia in 1955. Phylogenetic analysis of the E2 and capsid genes further revealed that YN12031 was located in the same clade as the Russian isolate LEIV/16275/Mag. Analysis of the homology of nucleotides and amino acids in the coding area and E2 gene demonstrated that the YN12031 isolated from the China-Laos border(tropical region) was related closest to the LEIV/16275/Mag isolate obtained in Russia(North frigid zone area) among other isolates studied. These results suggest that GETV can adapt to different geographical environments to propagate and evolve. Thus, strengthening the detection and monitoring of GETV and its related diseases is very crucial. | LI Yuan Yuan FU Shi Hong GUO Xiao Fang LEI Wen Wen LI Xiao Long SONG Jing Dong CAO Lei GAO Xiao Yan LYU Zhi HE Ying WANG Huan Yu REN Xiao Jie ZHOU Hong Ning WANG Gui Qin LIANG Guo Dong | 2017 | Biomedical and Environmental Sciences2017，30，3： | 12 |
| 5 | Association between Plasma Metal Levels and Diabetes Risk: a Case-control Study in China显示文摘Objective Many metals, some of which have been classified as environmental endocrine disruptors, are used extensively in everyday consumer products and are ubiquitous in our living environment. In the present study, we aimed to explore the associations between the prevalence risk of type 2 diabetes and plasma levels of 20 trace elements as well as those of heavy metals in a Han Chinese population. Methods We conducted a case-control study to investigate the associations between plasma concentrations of 20 metals and diabetes in Jiangsu province. A total of 122 newly diagnosed cases of type 2 diabetes and 429 matched controls were recruited from community physical examinations in Suzhou City of Jiangsu Province. Plasma metal levels were measured by inductively-coupled plasma mass spectrometry. Results After adjusting for confounders, plasma vanadium, chromium, manganese, copper, zinc, arsenic, selenium, strontium, palladium, cadmium, cesium, and barium were associated with diabetes risk(P < 0.05). The adjusted OR increased with increasing concentration of vanadium, manganese, copper, zinc, and cesium. Conclusion Many metals, including manganese, copper, zinc, arsenic, selenium, and cadmium in plasma, are associated with the morbidity of diabetes. Monitoring of environmental metal levels and further studies are urgently needed. | LI Xiu Ting YU Peng Fei GAO Yan GUO Wen Hui WANG Jun LIU Xin GU Ai Hua JI Gui Xiang DONG Qiu WANG Bo Shen CAO Ying ZHU Bao Li XIAO Hang | 2017 | Biomedical and Environmental Sciences2017，30，7： | 8 |
| 6 | Templated synthesis of Ti02 nanotube macrostructures and their photocatalytic properties显示文摘 | Hongbian Li Qiaoyu Zhou Yuntian Gao Xuchun Gui Long Yang Mingde Du Enzheng Shi Jidong Shi Anyuan Cao Ying Fang | 2015 | Nano Research2015，8，3： | 7 |
| 7 | An-Luo-Hua-Xian Pill Improves the Regression of Liver Fibrosis in Chronic Hepatitis B Patients Treated with Entecavir显示文摘Background and Aims:Chronic hepatitis B(CHB)can cause liver fibrosis and lead to cirrhosis and cancer.As the effectiveness of antiviral therapy to reverse liver fibrosis is limited,We aimed to evaluate the effect of An-Luo-Hua-Xian pill(ALHX)on fibrosis regression in CHB patients treated with entecavir(ETV).Methods:Treatment-naïve patients with CHB were randomly treated with ETV alone or combined with ALHX(ETV+ALHX)between October 1,2013 and December 31,2020.Demographic,laboratory,and liver histology data before and after 78 weeks of treatment were collected.The Ishak fibrosis score(F)was used and fibrosis regression required a decrease in F of≥1 after treatment.Results:A total of 780 patients were enrolled,and 394 with a second liver biopsy after treatment were included in the per-protocol population,132 in ETV group and 262 in ETV+ALHX group.After 78 weeks of treatment,the fibrosis regression rate in the ETV+ALHX group was significantly higher than that of the ETV group at baseline F≥3 patients:124/211(58.8%)vs.45/98(45.9%),p=0.035.The percentage of patients with a decreased liver stiffness measurement(LSM)was higher in the ETV+ALHX group:156/211(73.9%)vs.62/98(63.%),p=0.056.Logistic regression analysis showed that ETV combined with ALHX was associated with fibrosis regression[odds ratio(OR)=1.94,p=0.018],and a family history of hepatocellular carcinoma was on the contrary.(OR=0.41,p=0.031).Conclusions:ETV combined with ALHX increased liver fibrosis regression in CHB patients. | Yi-Qi Liu Chi Zhang Jia-Wen Li Li-Hua Cao Zhan-Qing Zhang Wei-Feng Zhao Qing-Hua Shang Da-Zhi Zhang An-Lin Ma Qing Xie Hong-Lian Gui Guo Zhang Ying-Xia Liu Jia Shang Shi-Bin Xie Jun Li Xu-Qing Zhang Zhi-Qiang Zou Yu-Ping Chen Zong Zhang Ming-Xiang Zhang Jun Cheng Fu-Chun Zhang Li-Hua Huang Jia-Bin Li Qing-Hua Meng Hai-Bin Yu Yu-Qiang Mi Yan-Zhong Peng Zhi-Jin Wang Li-Ming Chen Fan-Ping Meng Wan-Hua Ren Lang Bai Yi-Lan Zeng Rong Fan Xian-Zhi Lou Wei-Feng Liang Hui Liu Hui Zhuang Hong Zhao Gui-Qiang Wang | 2023 | Journal of Clinical and Translational Hepatology2023，11，2： | 7 |
| 8 | A draft sequence of the rice (Oryza sativa ssp. indica) genome显示文摘The sequence of the rice genome holds fundamental information for its biology, including physiology, genetics, development, and evolution, as well as information on many beneficial phenotypes of economic significance. Using a 'whole genome shotgun' approach, we have pro-duced a draft rice genome sequence of Oryza sativa ssp. in-dica, the major crop rice subspecies in China and many other regions of Asia. The draft genome sequence is constructed from over 4.3 million successful sequencing traces with an accumulative total length of 2214.9 Mb. The initial assembly of the non-redundant sequences reached 409.76 Mb in length, based on 3.30 million successful sequencing traces with a total length of 1797.4 Mb from an indica variant cultivar 93-11, giving an estimated coverage of 95.29% of the rice genome with an average base accuracy of higher than 99%. The coverage of the draft sequence, the randomness of the sequence distribution, and the consistency of BIG-ASSEM-BLER, a custom-designed software package | YU Jun, HU Songnian, WANG Jun,LI Songgang WONG Ka-Shu Gane, LIU Bin,DENG Yajun, DAI Li, ZHOU Yan,ZHANG Xiuqing, CAO Mengliang, LIU Jing,SUN Jiandong , TANG Jiabin, CHEN Yanjiong,HUANG Xiaobing, LIN Wei, YE Chen, TONG Wei,CONG Lijuan, GENG Jianing, HAN Yujun, LI Lin,LI Wei, HU Guangqiang, HUANG Xiangang,LI Wenjie, LI Jian, LIU Zhanwei, LI Long,LIU Jianping, Ql Qiuhui, LIU Jinsong, LI Li,WANG Xuegang, LU Hong, WU Tingling,ZHU Miao, Nl Peixiang, HAN Hua, DONG Wei,REN Xiaoyu, FENG Xiaoli, GUI Peng,LI Xianran, WANG Hao, XU Xin, ZHAI Wenxue,XU Zhao, ZHANG Jinsong, HE Sijie,ZHANG Jianguo, XU Jichen, ZHANG Kunlin,ZHENG Xianwu, DONG Jianhai, ZENG Wanyong,TAO Lin, CHEN Xuewei, HE Jun, LIU Daofeng,TIAN Wei, TIAN Chaoguang, XIA Hongai,LI Gang, GAO Hui, LI Ping, CHEN Wei ,WANG Xudong, ZHANG Yong, HU Jianfei,WANG Jing, LIU Song, YANG Jian,ZHANG Guangyu, XIONG Yuqing, LI Zhijie,MAO Long, ZHOU Chengshu, ZHU Zhen,CHEN Runsheng, HAO Bailin,ZHENG Weimou, CHEN Shouyi, QUO Wei,LI Guojie, LIU Siqi, HUANG Guyang,TAO Ming, WANG Jian, ZHU Lihuang,YUAN Longping& YANG HuanmingBeijing Genomics Institute/Center of Genomics & Bioinformatics, Chinese Academy of Sciences, Beijing 101300, China Hangzhou Genomics Institute/Institute of Bioinformatics of Zhejiang University/Key Laboratory of Bioinformatics of Zhejiang Province, Hangzhou 310007, China Institute of Genetics, Chinese Academy of Sciences, Beijing 100101, China National Hybrid Rice R & D Center, Changsha 410125, China Laboratory of Bioinformatics, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China College of Life Sciences, Peking University, Beijing 100871, China Institute of Theoretical Physics, Chinese Academy of Sciences, Beijing 1Q0080, China Digital China Ltd., Beijing 100080, China Institute of Computing Technology, Chinese Academy of Sciences, Beijing 100080, China Medical College, Xi’an Jiaotong University, Xi’an 710061, ChinaThese authors contributed equally to this work.Corresponding author.Corresponden | 2001 | Chinese Science Bulletin2001，46，23： | 6 |
| 9 | Clinical Characteristics of Hospitalized Patients with SARS-CoV-2 and Hepatitis B Virus Co-infection显示文摘Dear Editor,Coronavirus disease 2019(COVID-19)is a global pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-Co V-2).SARS-Co V-2 infection was first detected in Wuhan,China in late December 2019.The virus was spreading rapidly to other cities of China and accumulating cases had been reported(Li et al.2020). | Xiaoping Chen Qunqun Jiang Zhiyong Ma Jiaxin Ling Wenjia Hu Qian Cao Pingzheng Mo Lei Yao Rongrong Yang Shicheng Gao Xien Gui Wei Hou Yong Xiong Jinlin Li Yongxi Zhang | 2020 | Virologica Sinica2020，35，6： | 6 |
| 10 | Two new eudesmane sesquiterpenes from Lactuca sativa var.anagustata L显示文摘<正>Two new eudesmane sesquiterpene lactones were isolated from the stalk of Lactuca sativa var.anagustata L and their structureswere elucidated by means of spectroscopic methods,including 2D NMR(~1H-~1H COSY,HMBC and NOESY) as 1β-O-β-D-glucopyranosyl-4α-hydroxyl-5α,6β,11βH-eudesma-12,6α-olide(1) and 1β-hydroxyl-15-O-(p-methoxyphenylacetyl)-5α,6β,11βH-eudesma-3-en-12,6α-olide(2). | Yi Feng Han Gui Xiu Cao Min Xia | 2009 | Chinese Chemical Letters2009，20，10： | 4 |
| 11 | CNN-Based Intelligent Safety Surveillance in Green IoT Applications显示文摘Safety surveillance is considered one of the most important factors in many constructing industries for green internet of things(IoT)applications.However,traditional safety monitoring methods require a lot of labor source.In this paper,we propose intelligent safety surveillance(ISS)method using a convolutional neural network(CNN),which is an autosupervised method to detect workers whether or not wearing helmets.First,to train the CNN-based ISS model,the labeled datasets mainly come from two aspects:1)our labeled datasets with the full labeled on both helmet and pedestrian;2)public labeled datasets with the parts labeled either on the helmet or pedestrian.To fully take advantage of all datasets,we redesign CNN structure of network and loss functions based on YOLOv3.Then,we test our proposed ISS method based on the specific detection evaluation metrics.Finally,experimental results are given to show that our proposed ISS method enables the model to fully learn the labeled information from all datasets.When the threshold of intersection over union(IoU)between the predicted box and ground truth is set to 0.5,the average precision of pedestrians and helmets can reach 0.864 and 0.891,respectively. | Wengang Cao Jianing Zhang Changxin Cai Quan Chen Yu Zhao Yimo Lou Wei Jiang Guan Gui | 2021 | China Communications2021，18，1： | 4 |
| 12 | Enhanced bioactivity and interfacial bonding strength of Ti3Zr2Sn3Mo25Nb alloy through graded porosity and surface bioactivation显示文摘The gradient porous Ti3Zr2Sn3Mo25Nb(TLM)alloy rods were fabricated through sintering the alloyed powder to a solid core.The porous sample was then modified by a Micro Arc Oxidation(MAO)treatment in an electrolyte containing calcium and phosphate,a hydrothermal treatment enabled secondary microporous hydroxyapatite(HA)coating,and a further bone morphogenetic protein-2(BMP-2)loading treatment through immersion and freeze-drying.The treatment led to an orderly secondary microporous coating containing HA nano-particles and evenly distributed BMP-2 in the porous coatings.As a result,osteoblasts could adhere and grow well on the coatings with a high cell adhesion rate and cell functional activity.The in-situ shear testing indicated that the interfacial strength had been enhanced significantly.Improvement of the bond formation and osseointegration with the titanium implant is attributed to increased surface area for the cell to attach,creating voids for the cell to grow in,and activating titanium surface by introducing bioactive ingredients such as HA and BMP-2. | Sen Yu Zhe Yu Dagang Guo Hui Zhu Minghua Zhang Jianye Han Zhentao Yu Yemin Cao Gui Wang | 2022 | Journal of Materials Science & Technology2022，，5： | 3 |
| 13 | A single-center retrospective long-term analysis of 80 cases of ovarian Sertoli-Leydig cell tumors显示文摘To the Editor:Sertoli-Leydig cell tumors(SLCTs)are a rare type of sex cord-stromal tumor of the ovary,accounting for<0.5%of all ovarian tumors.[1]An accurate diagnosis and the knowledge of prognosis based on clinical and pathological features have important therapeutic implications;however,the rarity of SLCT renders collecting reliable data difficult.We aimed to analyze the features of SLCTs to clarify their relationship with the behavior of the tumor and explore reasonable modes of therapy. | Ni Yang Ting Gui Dong-Yan Cao Keng Shen Yan You | 2021 | Chinese Medical Journal2021，，19： | 3 |
| 14 | Effect of Octreotide on cell-cycle kinetics and serum CEA level in hepatic metastases of colonic adenocarcinoma显示文摘EfectofOctreotideoncelcyclekineticsandserumCEAlevelinhepaticmetastasesofcolonicadenocarcinomaLIURui1,WANGYuanHe2,TANGYan1an... | LIU Rui 1, WANG Yuan He 2, TANG Yan 1 and CAO Gui Song 1 | 1997 | World Journal of Gastroenterology1997，3，2： | 3 |
| 15 | Multidimensional clinical data denoising via Bayesian CP factorization显示文摘CANDECOMP/PARAFAC(CP) tensor factorization is an efficient technique for incomplete tensor-data processing through capturing the multilinear latent factors. Based on the incorporate a sparsity-inducing prior over multiple latent factors and appropriate hyper-priors over all hyper-parameters, a Bayesian-based hierarchical probabilistic CP factorization model could be formed. By this way, the rank of the incomplete tensor can be determined automatically. In this paper, we explored the tensor completion method in processing incomplete multidimensional electroencephalogram(EEG) and magnetic resonance imaging(MRI) clinical data. The empirical results indicated that the Bayesian CP tensor factorization of incomplete data method can effectively recover EEG signal with missing data and denoised the noisy MRI data. | CUI GaoChao ZHU Li GUI LiHua ZHAO QiBin ZHANG JianHai CAO JianTing | 2020 | Science China(Technological Sciences)2020，63，2： | 3 |
| 16 | Comparative study of HFACS and the 24Model accident causation models显示文摘A comparative study is conducted to compare the theory and application effect of two accident causation models, the human factors analysis and classification system(HFACS) and the accident causation ‘‘2-4'' model(24 Model), as well as to provide a reference for safety researchers and accident investigators to select an appropriate accident analysis method. The two models are compared in terms of their theoretical foundations, cause classifications, accident analysis processes, application ranges, and accident prevention strategies. A coal and gas outburst accident is then analyzed using both models, and the application results are compared. This study shows that both the 24 Model and HFACS have strong theoretical foundations, and they can each be applied in various domains. In addition, the cause classification in HFACS is more practical, and its accident analysis process is more convenient. On the other hand, the 24 Model includes external factors, which makes the cause analysis more systematic and comprehensive. Moreover, the 24 Model puts forward more corresponding measures to prevent accidents. | Gui Fu Jia-Lin Cao Lin Zhou Yuan-Chi Xiang | 2017 | Petroleum Science2017，14，3： | 3 |
| 17 | Effect of coarse TiN inclusions and microstructure on impact toughness fluctuation in Ti micro-alloyed steel显示文摘 | Tao Liu Mu-jun Long Deng-fu Chen Hua-mei Duan Lin-tao Gui Sheng Yu Jun-sheng Cao Hua-biao Chen He-lin Fan | 2018 | Journal of Iron and Steel Research(International)2018，25，10： | 3 |
| 18 | Chidamide combined with cyclophosphamide,doxorubicin,vincristine and prednisone in previously untreated patients with peripheral T-cell lymphoma显示文摘Objective:Chidamide is an oral histone deacetylase subtype-selective inhibitor approved for relapsed or refractory peripheral T-cell lymphoma(PTCL).This phase 1 b study evaluated the safety,pharmacokinetics,and preliminary efficacy of chidamide in combination with cyclophosphamide,doxorubicin,vincristine and prednisone(CHOP)for treatment-na?ve PTCL patients.Methods:This study was an open-label,multicenter trial composed of dose escalation and dose expansion.Patients received CHOP for six 21-d cycles and chidamide on d 1,4,8 and 11 in each cycle.Four dose levels of chidamide(20,25,30 and 35 mg)were evaluated.The primary objective was to evaluate the safety and tolerability of the combination regimen.Results:A total of 30 patients were evaluated in this study:15 in the dose-escalation part and 15 in the doseexpansion part.In the dose-escalation study,three patients were enrolled in the 35 mg chidamide cohort.One had dose-limiting toxicity with grade 3 vascular access complications,and one had grade 2 neutropenia with a sustained temperature>38°C.Dose escalation was stopped at this chidamide dose level.The most common(≥10%)grade 3 or 4 adverse events(AEs)were leukopenia(90.0%),neutropenia(83.3%),vomiting(13.3%),thrombocytopenia(10.0%)and febrile neutropenia(10.0%).No significant changes in chidamide pharmacokinetic properties were observed before and after combination treatment.The objective response rate for the 28 patients evaluable for preliminary efficacy was 89.3%(25/28),with 16(57.1%)achieving complete response or unconfirmed complete response.The estimated median progression-free survival was 14.0 months.In summary,we chose chidamide 30 mg as the recommended dose for phase 2.Conclusions:The addition of chidamide to standard CHOP chemotherapy was tolerable with promising preliminary efficacy in previously untreated PTCL patients,which supports further clinical studies with this combination regimen for the frontline treatment of PTCL. | Lin Gui Junning Cao Dongmei Ji Huilai Zhang Qian Fan Jun Zhu Yuqin Song Shiyu Jiang Zhiqiang Ning Jia Yu Yuankai Shi | 2021 | Chinese Journal of Cancer Research2021，33，5： | 3 |
| 19 | Simultaneous elimination of cancer stem cells and bulk cancer cells by cationic-lipid-assisted nanoparticles for cancer therapy显示文摘有说服力的证据显示在恶意的肿瘤以内的癌症干细胞(CSC ) 的存在为化疗的失败主要负责。因此而不是仅仅指向体积癌症房间, CSC 和体积癌症房间的同时的消除是必要的改进治疗学的结果。此处,我们设计了 cationic-lipid-assisted nanoparticles DTXL NP 为常规化学疗法的 agentdocetaxel (DTXL ) 和指向 BMI-1 (siBMI-1 ) 的小介入 RNA (siRNA ) 的同时的封装的 siRNA 。我们证实了那 nanoparticles DTX LNP siBMI-1 有效地交付两个治疗学的代理人进 CSC 和体积癌症房间。体积癌症房间被在 DTX LNP siBMI-1 。在胸 CSC, BMI-1 表示是显著地由 DTX LNP siBMI-1 ;因而, stemness 被减少,到 DTXL 的 CSC 的 chemosensitivity 被提高,导致 CSC 的消除。因此,经由 DTX LNP siBMI-1 , siBMI-1 和 DTXL 的联合完全禁止了肿瘤生长并且由在一个 MDA-MB-231 orthotropic 肿瘤的一个鼠科的模型 CSC 和体积癌症房间杀死的 synergistic 阻止了恶化。 | Kaige Chen Song Shen Gui Zhao Zhiting Cao Xianzhu Yang Jun Wang | 2018 | Nano Research2018，11，8： | 2 |
| 20 | Characteristics of the subglacially-formed debris-rich chemical deposits and related subglacial processes of Qiangyong Glacier,Tibet显示文摘Subglacially-formed debris-rich chemical deposits were found both on bedrock surface and in bedrock crevice on the edge of Qiangyong Glacier, one of the continental glaciers in Tibet. Grain size distribution, internal structures and chemical components of the chemical deposits were analyzed. It can be inferred that the temperature of some part of the ice-bedrock interface is close to the melting point and there exists pressure melting water under Qiangyong Glacier. Debris, especially those from continental aerosols, can release Ca^++ in the water. At the lee-side of obstacles on glacier bed the CO2 in the melting water might escape from the water and the melting water might refreeze due to the dramatically reduced pressure, making the enrichment and precipitation of CaCO3. The existence of subglacial melting water and the process of regelation under Qiangyong Glacier indicate that sliding could contribute some proportion to the entire movement of Qiangyong Glacier and it belongs to multiolex cold-temperate glaciers. | LUO Risheng, CAO Jim, LIU Gengnian, GUI Zhijiu(College of Environmental Sciences, Peking University, Beijing 100871, China) | 2003 | Journal of Geographical Sciences2003，13，4： | 2 |
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